Monoisononyl phthalate (BioDeep_00000841929)
代谢物信息卡片
Monoisononyl phthalate
化学式: C17H24O4 (292.1674504)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)CCCCCCOC(=O)C1=CC=CC=C1C(=O)O
InChI: InChI=1S/C17H24O4/c1-13(2)9-5-3-4-8-12-21-17(20)15-11-7-6-10-14(15)16(18)19/h6-7,10-11,13H,3-5,8-9,12H2,1-2H3,(H,18,19)
描述信息
A phthalic acid monoester obtained by formal condensation of one of the carboxy groups of phthalic acid with the hydroxy group of isononanol.
同义名列表
1 个代谢物同义名
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:132593
- PubChem: 110394
- CAS: 106610-61-1
- CAS: 68515-53-7
- MetaboLights: MTBLC132593
- RefMet: Monoisononyl phthalate
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Seung-Hyun Jeong, Ji-Hun Jang, Hea-Young Cho, Yong-Bok Lee. Toxicokinetics of diisobutyl phthalate and its major metabolite, monoisobutyl phthalate, in rats: UPLC-ESI-MS/MS method development for the simultaneous determination of diisobutyl phthalate and its major metabolite, monoisobutyl phthalate, in rat plasma, urine, feces, and 11 various tissues collected from a toxicokinetic study.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2020 Nov; 145(?):111747. doi:
10.1016/j.fct.2020.111747. [PMID: 32926938] - Anna Mentor, Björn Brunström, Anna Mattsson, Maria Jönsson. Developmental exposure to a human relevant mixture of endocrine disruptors alters metabolism and adipogenesis in zebrafish (Danio rerio).
Chemosphere.
2020 Jan; 238(?):124584. doi:
10.1016/j.chemosphere.2019.124584. [PMID: 31470313] - Hiroshi Iwata, Masatomo Goto, Norifumi Sakai, Hiroshi Suemizu, Hiroshi Yamazaki. Predictability of human pharmacokinetics of diisononyl phthalate (DINP) using chimeric mice with humanized liver.
Xenobiotica; the fate of foreign compounds in biological systems.
2019 Nov; 49(11):1311-1322. doi:
10.1080/00498254.2018.1564087. [PMID: 30589368] - Tomonori Miura, Hiroshi Suemizu, Masatomo Goto, Norifumi Sakai, Hiroshi Iwata, Makiko Shimizu, Hiroshi Yamazaki. Human urinary concentrations of monoisononyl phthalate estimated using physiologically based pharmacokinetic modeling and experimental pharmacokinetics in humanized-liver mice orally administered with diisononyl phthalate.
Xenobiotica; the fate of foreign compounds in biological systems.
2019 May; 49(5):513-520. doi:
10.1080/00498254.2018.1471753. [PMID: 29708805] - Anastasia Repouskou, Emily Panagiotidou, Lydia Panagopoulou, Pernilla Larsdotter Bisting, Astrud R Tuck, Marcus O D Sjödin, Johan Lindberg, Evangelos Bozas, Joëlle Rüegg, Chris Gennings, Carl-Gustaf Bornehag, Pauliina Damdimopoulou, Antonios Stamatakis, Efthymia Kitraki. Gestational exposure to an epidemiologically defined mixture of phthalates leads to gonadal dysfunction in mouse offspring of both sexes.
Scientific reports.
2019 04; 9(1):6424. doi:
10.1038/s41598-019-42377-6. [PMID: 31015488] - Bin Wang, Hexing Wang, Wei Zhou, Yue Chen, Ying Zhou, Qingwu Jiang. Urinary excretion of phthalate metabolites in school children of China: implication for cumulative risk assessment of phthalate exposure.
Environmental science & technology.
2015 Jan; 49(2):1120-9. doi:
10.1021/es504455a. [PMID: 25496010] - Ulla Nordström Joensen, Niels Jørgensen, Michael Meldgaard, Hanne Frederiksen, Anna-Maria Andersson, Torkil Menné, Jeanne Duus Johansen, Berit Christina Carlsen, Steen Stender, Pal Bela Szecsi, Niels Erik Skakkebæk, Ewa Rajpert-De Meyts, Jacob P Thyssen. Associations of filaggrin gene loss-of-function variants with urinary phthalate metabolites and testicular function in young Danish Men.
Environmental health perspectives.
2014 Apr; 122(4):345-50. doi:
10.1289/ehp.1306720. [PMID: 24380925] - Ulla Nordström Joensen, Hanne Frederiksen, Martin Blomberg Jensen, Mette Petri Lauritsen, Inge Ahlmann Olesen, Tina Harmer Lassen, Anna-Maria Andersson, Niels Jørgensen. Phthalate excretion pattern and testicular function: a study of 881 healthy Danish men.
Environmental health perspectives.
2012 Oct; 120(10):1397-403. doi:
10.1289/ehp.1205113. [PMID: 22832070] - Gurusankar Saravanabhavan, Janine Murray. Human biological monitoring of diisononyl phthalate and diisodecyl phthalate: a review.
Journal of environmental and public health.
2012; 2012(?):810501. doi:
10.1155/2012/810501. [PMID: 22505951] - Lena Olsén, Erik Lampa, Detlef A Birkholz, Lars Lind, P Monica Lind. Circulating levels of bisphenol A (BPA) and phthalates in an elderly population in Sweden, based on the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS).
Ecotoxicology and environmental safety.
2012 Jan; 75(1):242-8. doi:
10.1016/j.ecoenv.2011.09.004. [PMID: 21955883] - Antonia M Calafat, Lee-Yang Wong, Manori J Silva, Ella Samandar, James L Preau, Lily T Jia, Larry L Needham. Selecting adequate exposure biomarkers of diisononyl and diisodecyl phthalates: data from the 2005-2006 National Health and Nutrition Examination Survey.
Environmental health perspectives.
2011 Jan; 119(1):50-5. doi:
10.1289/ehp.1002316. [PMID: 20870567] - Malene Boas, Hanne Frederiksen, Ulla Feldt-Rasmussen, Niels E Skakkebæk, Laszlo Hegedüs, Linda Hilsted, Anders Juul, Katharina M Main. Childhood exposure to phthalates: associations with thyroid function, insulin-like growth factor I, and growth.
Environmental health perspectives.
2010 Oct; 118(10):1458-64. doi:
10.1289/ehp.0901331. [PMID: 20621847] - Yayoi Suzuki, Mayu Niwa, Jun Yoshinaga, Yoshifumi Mizumoto, Shigeko Serizawa, Hiroaki Shiraishi. Prenatal exposure to phthalate esters and PAHs and birth outcomes.
Environment international.
2010 Oct; 36(7):699-704. doi:
10.1016/j.envint.2010.05.003. [PMID: 20605637] - Hanne Frederiksen, Niels Jørgensen, Anna-Maria Andersson. Correlations between phthalate metabolites in urine, serum, and seminal plasma from young Danish men determined by isotope dilution liquid chromatography tandem mass spectrometry.
Journal of analytical toxicology.
2010 Sep; 34(7):400-10. doi:
10.1093/jat/34.7.400. [PMID: 20822678] - Fumio Kondo, Yoshitomo Ikai, Rumiko Hayashi, Masanao Okumura, Satoshi Takatori, Hiroyuki Nakazawa, Shun-ichiro Izumi, Tsunehisa Makino. Determination of five phthalate monoesters in human urine using gas chromatography-mass spectrometry.
Bulletin of environmental contamination and toxicology.
2010 Jul; 85(1):92-6. doi:
10.1007/s00128-010-0051-8. [PMID: 20574658] - Sonia Hernández-Díaz, Allen A Mitchell, Katherine E Kelley, Antonia M Calafat, Russ Hauser. Medications as a potential source of exposure to phthalates in the U.S. population.
Environmental health perspectives.
2009 Feb; 117(2):185-9. doi:
10.1289/ehp.11766. [PMID: 19270786] - Elizabeth E Hatch, Jessica W Nelson, M Mustafa Qureshi, Janice Weinberg, Lynn L Moore, Martha Singer, Thomas F Webster. Association of urinary phthalate metabolite concentrations with body mass index and waist circumference: a cross-sectional study of NHANES data, 1999-2002.
Environmental health : a global access science source.
2008 Jun; 7(?):27. doi:
10.1186/1476-069x-7-27. [PMID: 18522739] - Richard W Stahlhut, Edwin van Wijngaarden, Timothy D Dye, Stephen Cook, Shanna H Swan. Concentrations of urinary phthalate metabolites are associated with increased waist circumference and insulin resistance in adult U.S. males.
Environmental health perspectives.
2007 Jun; 115(6):876-82. doi:
10.1289/ehp.9882. [PMID: 17589594] - Manori J Silva, John A Reidy, James L Preau, Larry L Needham, Antonia M Calafat. Oxidative metabolites of diisononyl phthalate as biomarkers for human exposure assessment.
Environmental health perspectives.
2006 Aug; 114(8):1158-61. doi:
10.1289/ehp.8865. [PMID: 16882519] - G Lottrup, A-M Andersson, H Leffers, G K Mortensen, J Toppari, N E Skakkebaek, K M Main. Possible impact of phthalates on infant reproductive health.
International journal of andrology.
2006 Feb; 29(1):172-80; discussion 181. doi:
10.1111/j.1365-2605.2005.00642.x. [PMID: 16466537] - Manori J Silva, Dana B Barr, John A Reidy, Nicole A Malek, Carolyn C Hodge, Samuel P Caudill, John W Brock, Larry L Needham, Antonia M Calafat. Urinary levels of seven phthalate metabolites in the U.S. population from the National Health and Nutrition Examination Survey (NHANES) 1999-2000.
Environmental health perspectives.
2004 Mar; 112(3):331-8. doi:
10.1289/ehp.6723. [PMID: 14998749]