N-[5-[[4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl]sulfamoyl]-4-methyl-1,3-thiazol-2-yl]acetamide (BioDeep_00000841904)

   


代谢物信息卡片


N-[5-[[4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl]sulfamoyl]-4-methyl-1,3-thiazol-2-yl]acetamide

化学式: C15H13F6N3O4S2 (477.025165)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC1=C(SC(=N1)NC(=O)C)S(=O)(=O)NC2=CC=C(C=C2)C(C(F)(F)F)(C(F)(F)F)O
InChI: InChI=1S/C15H13F6N3O4S2/c1-7-11(29-12(22-7)23-8(2)25)30(27,28)24-10-5-3-9(4-6-10)13(26,14(16,17)18)15(19,20)21/h3-6,24,26H,1-2H3,(H,22,23,25)

描述信息

同义名列表

1 个代谢物同义名

N-[5-[[4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl]sulfamoyl]-4-methyl-1,3-thiazol-2-yl]acetamide



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

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PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

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文献列表

  • Siqi Wang, Wenlin Deng, Fang Li, Y E Chen, P U Wang. Blockade of T helper 17 cell function ameliorates recurrent Clostridioides difficile infection in mice. Acta biochimica et biophysica Sinica. 2021 Oct; 53(10):1290-1299. doi: 10.1093/abbs/gmab107. [PMID: 34379099]
  • P C Wei, L Tong, R Li. [Effect of RORC inhibitor on HIF-1α and VEGF in nasal mucosa of allergic rhinitis of mice]. Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery. 2018 Oct; 53(10):751-756. doi: 10.3760/cma.j.issn.1673-0860.2018.10.007. [PMID: 30347534]
  • Cuipei Lin, Hanqing Wang, Hua Sun, Chengju Xiao, Yunxia Xue, Jun Liu, Ting Fu, Yifei Wang, Dong Dong, Zhijie Li. Development and validation of an ultra-performance liquid chromatography-tandem mass spectrometry method for quantification of SR1001, an inverse agonist of retinoid-related orphan receptors, and its application to pharmacokinetic studies in streptozotocin-induced diabetic mice. Journal of pharmaceutical and biomedical analysis. 2017 Sep; 143(?):94-100. doi: 10.1016/j.jpba.2017.05.022. [PMID: 28578255]
  • Yuko Nishiyama, Masahiko Nakamura, Takashi Misawa, Madoka Nakagomi, Makoto Makishima, Minoru Ishikawa, Yuichi Hashimoto. Structure-activity relationship-guided development of retinoic acid receptor-related orphan receptor gamma (RORγ)-selective inverse agonists with a phenanthridin-6(5H)-one skeleton from a liver X receptor ligand. Bioorganic & medicinal chemistry. 2014 May; 22(9):2799-808. doi: 10.1016/j.bmc.2014.03.007. [PMID: 24702856]
  • Naresh Kumar, Laura A Solt, Juliana J Conkright, Yongjun Wang, Monica A Istrate, Scott A Busby, Ruben D Garcia-Ordonez, Thomas P Burris, Patrick R Griffin. The benzenesulfoamide T0901317 [N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide] is a novel retinoic acid receptor-related orphan receptor-alpha/gamma inverse agonist. Molecular pharmacology. 2010 Feb; 77(2):228-36. doi: 10.1124/mol.109.060905. [PMID: 19887649]