Thioacetamide-S-oxide (BioDeep_00000841898)
代谢物信息卡片
化学式: C2H5NOS (91.009184)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=S=O)N
InChI: InChI=1S/C2H5NOS/c1-2(3)5-4/h3H2,1H3
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Takujiro Homma, Takaya Shirato, Ryusuke Akihara, Sho Kobayashi, Jaeyong Lee, Ken-Ichi Yamada, Satoshi Miyata, Motoko Takahashi, Junichi Fujii. Mice deficient in aldo-keto reductase 1a (Akr1a) are resistant to thioacetamide-induced liver injury.
Toxicology letters.
2018 Sep; 294(?):37-43. doi:
10.1016/j.toxlet.2018.05.015
. [PMID: 29763686] - Diganta Sarma, Heather Hajovsky, Yakov M Koen, Nadezhda A Galeva, Todd D Williams, Jeffrey L Staudinger, Robert P Hanzlik. Covalent modification of lipids and proteins in rat hepatocytes and in vitro by thioacetamide metabolites.
Chemical research in toxicology.
2012 Sep; 25(9):1868-77. doi:
10.1021/tx3001658
. [PMID: 22667464] - Heather Hajovsky, Gang Hu, Yakov Koen, Diganta Sarma, Wenqi Cui, David S Moore, Jeff L Staudinger, Robert P Hanzlik. Metabolism and toxicity of thioacetamide and thioacetamide S-oxide in rat hepatocytes.
Chemical research in toxicology.
2012 Sep; 25(9):1955-63. doi:
10.1021/tx3002719
. [PMID: 22867114] - Jaya Chilakapati, Midhun C Korrapati, Ronald A Hill, Alan Warbritton, John R Latendresse, Harihara M Mehendale. Toxicokinetics and toxicity of thioacetamide sulfoxide: a metabolite of thioacetamide.
Toxicology.
2007 Feb; 230(2-3):105-16. doi:
10.1016/j.tox.2006.11.050
. [PMID: 17187915] - Teck Yew Low, Chon Kar Leow, Manuel Salto-Tellez, Maxey C M Chung. A proteomic analysis of thioacetamide-induced hepatotoxicity and cirrhosis in rat livers.
Proteomics.
2004 Dec; 4(12):3960-74. doi:
10.1002/pmic.200400852
. [PMID: 15526343] - M C Dyroff, R A Neal. Studies of the mechanism of metabolism of thioacetamide s-oxide by rat liver microsomes.
Molecular pharmacology.
1983 Jan; 23(1):219-27. doi:
NULL
. [PMID: 6408387] - H V Vadi, R A Neal. Microsomal activation of thioacetamide-S-oxide to a metabolite(s) that covalently binds to calf thymus DNA and other polynucleotides.
Chemico-biological interactions.
1981 Apr; 35(1):25-38. doi:
10.1016/0009-2797(81)90061-2
. [PMID: 6162577]