7-(Dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol (BioDeep_00000841821)

   


代谢物信息卡片


7-(Dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol

化学式: C16H25NO (247.193604)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCCN(CCC)C1CCC2=C(C1)C=C(C=C2)O
InChI: InChI=1S/C16H25NO/c1-3-9-17(10-4-2)15-7-5-13-6-8-16(18)12-14(13)11-15/h6,8,12,15,18H,3-5,7,9-11H2,1-2H3

描述信息

D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018491 - Dopamine Agonists

同义名列表

1 个代谢物同义名

7-(Dipropylamino)-5,6,7,8-tetrahydronaphthalen-2-ol



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Eriko Ikeda, Naoya Matsunaga, Keisuke Kakimoto, Kengo Hamamura, Akane Hayashi, Satoru Koyanagi, Shigehiro Ohdo. Molecular mechanism regulating 24-hour rhythm of dopamine D3 receptor expression in mouse ventral striatum. Molecular pharmacology. 2013 May; 83(5):959-67. doi: 10.1124/mol.112.083535. [PMID: 23429911]
  • Jose R Eguibar, Ma del Carmen Cortes, Manuel Lara-Lozano, Diana M Mendiola. Dopaminergic D2-like agonists produce yawning in the myelin mutant taiep and Sprague-Dawley rats. Pharmacology, biochemistry, and behavior. 2012 Jul; 102(1):118-23. doi: 10.1016/j.pbb.2012.03.020. [PMID: 22497991]
  • P Benjamin Everett, Susan E Senogles. D3 dopamine receptor signals to activation of phospholipase D through a complex with Rho. Journal of neurochemistry. 2010 Feb; 112(4):963-71. doi: 10.1111/j.1471-4159.2009.06508.x. [PMID: 20021566]
  • Mark J Ferris, Charles F Mactutus, Janelle M Silvers, Ulla Hasselrot, Stephane A Beaudin, Barbara J Strupp, Rosemarie M Booze. Sex mediates dopamine and adrenergic receptor expression in adult rats exposed prenatally to cocaine. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 2007 Nov; 25(7):445-54. doi: 10.1016/j.ijdevneu.2007.08.009. [PMID: 17933484]
  • P Benjamin Everett, Susan E Senogles. D3 dopamine receptor activates phospholipase D through a pertussis toxin-insensitive pathway. Neuroscience letters. 2004 Nov; 371(1):34-9. doi: 10.1016/j.neulet.2004.08.033. [PMID: 15500962]
  • Rui Pedrosa, Pedro Gomes, Ulrich Hopfer, Pedro A Jose, Patrício Soares-da-Silva. Gialpha3 protein-coupled dopamine D3 receptor-mediated inhibition of renal NHE3 activity in SHR proximal tubular cells is a PLC-PKC-mediated event. American journal of physiology. Renal physiology. 2004 Nov; 287(5):F1059-66. doi: 10.1152/ajprenal.00139.2004. [PMID: 15265766]
  • Wayne G Brake, Tie Yuan Zhang, Josie Diorio, Michael J Meaney, Alain Gratton. Influence of early postnatal rearing conditions on mesocorticolimbic dopamine and behavioural responses to psychostimulants and stressors in adult rats. The European journal of neuroscience. 2004 Apr; 19(7):1863-74. doi: 10.1111/j.1460-9568.2004.03286.x. [PMID: 15078560]
  • Woo-Kyu Park, Daeyoung Jeong, Cheol-Won Yun, Sunghou Lee, Heeyeong Cho, Gun-Do Kim, Hun Yeong Koh, Ae Nim Pae, Yong Seo Cho, Kyung Il Choi, Ji Young Jung, Sun Ho Jung, Jae Yang Kong. Pharmacological actions of a novel and selective dopamine D3 receptor antagonist, KCH-1110. Pharmacological research. 2003 Dec; 48(6):615-22. doi: 10.1016/s1043-6618(03)00242-1. [PMID: 14527827]
  • Judith Varady, Xihan Wu, Xueliang Fang, Ji Min, Zengjian Hu, Beth Levant, Shaomeng Wang. Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach. Journal of medicinal chemistry. 2003 Oct; 46(21):4377-92. doi: 10.1021/jm030085p. [PMID: 14521403]
  • Gerd Luippold, Claudia Zimmermann, Matthias Mai, Doris Kloor, Dorothea Starck, Gerhard Gross, Bernd Mühlbauer. Dopamine D(3) receptors and salt-dependent hypertension. Journal of the American Society of Nephrology : JASN. 2001 Nov; 12(11):2272-2279. doi: 10.1681/asn.v12112272. [PMID: 11675403]
  • Vihang A Narkar, Tahir Hussain, Carlos Pedemonte, Mustafa F Lokhandwala. Dopamine D(2) receptor activation causes mitogenesis via p44/42 mitogen-activated protein kinase in opossum kidney cells. Journal of the American Society of Nephrology : JASN. 2001 Sep; 12(9):1844-1852. doi: 10.1681/asn.v1291844. [PMID: 11518777]
  • E M Byrnes, J J Byrnes, R S Bridges. Increased sensitivity of dopamine systems following reproductive experience in rats. Pharmacology, biochemistry, and behavior. 2001 Mar; 68(3):481-9. doi: 10.1016/s0091-3057(01)00449-x. [PMID: 11325402]
  • G Luippold, S Schneider, V Vallon, H Osswald, B Mühlbauer. Postglomerular vasoconstriction induced by dopamine D(3) receptor activation in anesthetized rats. American journal of physiology. Renal physiology. 2000 Apr; 278(4):F570-5. doi: 10.1152/ajprenal.2000.278.4.f570. [PMID: 10751217]
  • B Mühlbauer, E Küster, G Luippold. Dopamine D(3) receptors in the rat kidney: role in physiology and pathophysiology. Acta physiologica Scandinavica. 2000 Jan; 168(1):219-23. doi: 10.1046/j.1365-201x.2000.00665.x. [PMID: 10691804]
  • A Raurich, G Mengod, F Artigas, R Cortés. Displacement of the binding of 5-HT(1A) receptor ligands to pre- and postsynaptic receptors by (-)pindolol. A comparative study in rodent, primate and human brain. Synapse (New York, N.Y.). 1999 Oct; 34(1):68-76. doi: 10.1002/(sici)1098-2396(199910)34:1<68::aid-syn8>3.0.co;2-z. [PMID: 10459173]
  • N Sartania, P G Strange. Role of conserved serine residues in the interaction of agonists with D3 dopamine receptors. Journal of neurochemistry. 1999 Jun; 72(6):2621-4. doi: 10.1046/j.1471-4159.1999.0722621.x. [PMID: 10349875]
  • G Luippold, E Küster, V Vallon, H Osswald, B Mühlbauer. Dopamine D3 receptors in the rat kidney: glomerular and tubular actions. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 1999; 14 Suppl 4(?):24-5. doi: 10.1093/ndt/14.suppl_4.24. [PMID: 10463201]
  • G Luippold, E Küster, T O Joos, B Mühlbauer. Dopamine D3 receptor activation modulates renal function in anesthetized rats. Naunyn-Schmiedeberg's archives of pharmacology. 1998 Dec; 358(6):690-3. doi: 10.1007/pl00005314. [PMID: 9879731]
  • P Barili, A Ricci, E Baldoni, F Mignini, F Amenta. Pharmacological characterisation and autoradiographic localisation of a putative dopamine D3 receptor in the rat kidney. European journal of pharmacology. 1997 Oct; 338(1):89-95. doi: 10.1016/s0014-2999(97)01303-4. [PMID: 9408008]
  • G Flores, G K Wood, J J Liang, R Quirion, L K Srivastava. Enhanced amphetamine sensitivity and increased expression of dopamine D2 receptors in postpubertal rats after neonatal excitotoxic lesions of the medial prefrontal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience. 1996 Nov; 16(22):7366-75. doi: . [PMID: 8929443]
  • V J Watts, K A Neve. Sensitization of endogenous and recombinant adenylate cyclase by activation of D2 dopamine receptors. Molecular pharmacology. 1996 Oct; 50(4):966-76. doi: . [PMID: 8863843]
  • K Uvnäs-Moberg, S Ahlenius, P Alster, V Hillegaart. Effects of selective serotonin and dopamine agonists on plasma levels of glucose, insulin and glucagon in the rat. Neuroendocrinology. 1996 Mar; 63(3):269-74. doi: 10.1159/000126970. [PMID: 8677015]
  • M Kurashima, M Domae, T Inoue, M Nagashima, K Yamada, K Shirakawa, T Furukawa. Inhibitory effects of putative dopamine D3 receptor agonists, 7-OH-DPAT and quinpirole, on prolactin secretion in rats. Pharmacology, biochemistry, and behavior. 1996 Feb; 53(2):379-83. doi: 10.1016/0091-3057(95)02037-3. [PMID: 8808147]
  • K Uvnäs-Moberg, P Alster, V Hillegaart, S Ahlenius. Suggestive evidence for a DA D3 receptor-mediated increase in the release of oxytocin in the male rat. Neuroreport. 1995 Jun; 6(9):1338-40. doi: 10.1097/00001756-199506090-00027. [PMID: 7669999]
  • S K Sharma, K Dakshinamurti. Effects of serotonergic agents on plasma prolactin levels in pyridoxine-deficient adult male rats. Neurochemical research. 1994 Jun; 19(6):687-92. doi: 10.1007/bf00967707. [PMID: 8065526]
  • J G Hensler, R C Ferry, D M Labow, G B Kovachich, A Frazer. Quantitative autoradiography of the serotonin transporter to assess the distribution of serotonergic projections from the dorsal raphe nucleus. Synapse (New York, N.Y.). 1994 May; 17(1):1-15. doi: 10.1002/syn.890170102. [PMID: 8042142]
  • G Machata, G L Dadisch. [Current possibilities for analysis of etilefrin]. Beitrage zur gerichtlichen Medizin. 1978; 36(?):37-9. doi: NULL. [PMID: 31157]