Fumaraldehyde (BioDeep_00000841792)
代谢物信息卡片
化学式: C4H4O2 (84.0211284)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(=CC=O)C=O
InChI: InChI=1S/C4H4O2/c5-3-1-2-4-6/h1-4H/b2-1+
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Weifeng Yang, Lina Ma, Sidi Li, Kaiyu Cui, Lei Lei, Zuguang Ye. Evaluation of the Cardiotoxicity of Evodiamine In Vitro and In Vivo.
Molecules (Basel, Switzerland).
2017 Jun; 22(6):. doi:
10.3390/molecules22060943
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Physiology & behavior.
2016 Apr; 157(?):39-46. doi:
10.1016/j.physbeh.2016.01.037
. [PMID: 26825251] - M I Churchwell, R C Scheri, L S Von Tungeln, G Gamboa da Costa, F A Beland, D R Doerge. Evaluation of serum and liver toxicokinetics for furan and liver DNA adduct formation in male Fischer 344 rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2015 Dec; 86(?):1-8. doi:
10.1016/j.fct.2015.08.029
. [PMID: 26364877] - Alex E Grill, Thaddeus Schmitt, Leah A Gates, Ding Lu, Dipankar Bandyopadhyay, Jian-Min Yuan, Sharon E Murphy, Lisa A Peterson. Abundant Rodent Furan-Derived Urinary Metabolites Are Associated with Tobacco Smoke Exposure in Humans.
Chemical research in toxicology.
2015 Jul; 28(7):1508-16. doi:
10.1021/acs.chemrestox.5b00189
. [PMID: 26114498] - Ying-Zhong He, Xue-Fan Gu, Li-Hua Lu, Li-Li Liang. The oxidative molecular regulation mechanism of NOX in children with phenylketonuria.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience.
2014 Nov; 38(?):178-83. doi:
10.1016/j.ijdevneu.2014.09.002
. [PMID: 25256805] - Enting Wang, Fang Chen, Xiaosong Hu, Yuan Yuan. Protective effects of apigenin against furan-induced toxicity in mice.
Food & function.
2014 Aug; 5(8):1804-12. doi:
10.1039/c4fo00038b
. [PMID: 24914499] - Da-wei Zhang, Zhen-lin Wang, Wei Qi, Wei Lei, Guang-yue Zhao. Cordycepin (3'-deoxyadenosine) down-regulates the proinflammatory cytokines in inflammation-induced osteoporosis model.
Inflammation.
2014 Aug; 37(4):1044-9. doi:
10.1007/s10753-014-9827-z
. [PMID: 24493324] - Lin Yuan, Xuezhu Gu, Zhenhua Yin, Wenyi Kang. Antioxidant activities in vitro and hepatoprotective effects of Nelumbo nucifera leaves in vivo.
African journal of traditional, complementary, and alternative medicines : AJTCAM.
2014; 11(3):85-91. doi:
10.4314/ajtcam.v11i3.12
. [PMID: 25371567] - Miaomiao Wu, Hao Xiao, Wenkai Ren, Jie Yin, Bie Tan, Gang Liu, Lili Li, Charles Martin Nyachoti, Xia Xiong, Guoyao Wu. Therapeutic effects of glutamic acid in piglets challenged with deoxynivalenol.
PloS one.
2014; 9(7):e100591. doi:
10.1371/journal.pone.0100591
. [PMID: 24984001] - Shariq Naeem Syed, Waseem Rizvi, Anil Kumar, Aijaz Ahmad Khan, Shagufta Moin, Akif Ahsan. In vitro antioxidant and in vivo hepatoprotective activity of leave extract of Raphanus sativus in rats using CCL4 model.
African journal of traditional, complementary, and alternative medicines : AJTCAM.
2014; 11(3):102-6. doi:
10.4314/ajtcam.v11i3.15
. [PMID: 25371570] - Haipeng Gu, Xuezhu Gu, Qitai Xu, Wen-yi Kang. Antioxidant activity in vitro and hepatoprotective effect of Phlomis maximowiczii in vivo.
African journal of traditional, complementary, and alternative medicines : AJTCAM.
2014; 11(3):46-52. doi:
10.4314/ajtcam.v11i3.8
. [PMID: 25371563] - Gang Wang, Bing Han, Haoxin Zhou, Linfeng Wu, Yongwei Wang, Guang Jia, Jiachen Lv, Zhuoxin Cheng, Shangha Pan, Ji Liu, Yinan Zhou, Bei Sun. Inhibition of hydrogen sulfide synthesis provides protection for severe acute pancreatitis rats via apoptosis pathway.
Apoptosis : an international journal on programmed cell death.
2013 Jan; 18(1):28-42. doi:
10.1007/s10495-012-0770-x
. [PMID: 23054084] - Chunchao Han, Jianyou Guo. Antibacterial and anti-inflammatory activity of traditional Chinese herb pairs, Angelica sinensis and Sophora flavescens.
Inflammation.
2012 Jun; 35(3):913-9. doi:
10.1007/s10753-011-9393-6
. [PMID: 21976127] - Xiu-Hua Zhang, Hong Lei, Ai-Jun Liu, Ying-Xin Zou, Fu-Ming Shen, Ding-Feng Su. Increased oxidative stress is responsible for severer cerebral infarction in stroke-prone spontaneously hypertensive rats.
CNS neuroscience & therapeutics.
2011 Dec; 17(6):590-8. doi:
10.1111/j.1755-5949.2011.00271.x
. [PMID: 22117799] - Lisa A Peterson, Martin B Phillips, Ding Lu, Mathilde M Sullivan. Polyamines are traps for reactive intermediates in furan metabolism.
Chemical research in toxicology.
2011 Nov; 24(11):1924-36. doi:
10.1021/tx200273z
. [PMID: 21842885] - Carolin Hamberger, Marco Kellert, Ute M Schauer, Wolfgang Dekant, Angela Mally. Hepatobiliary toxicity of furan: identification of furan metabolites in bile of male f344/n rats.
Drug metabolism and disposition: the biological fate of chemicals.
2010 Oct; 38(10):1698-706. doi:
10.1124/dmd.109.031781
. [PMID: 20639435] - Jian-Hua Chen, Xin-Guo Zhang, Yu-Tao Jiang, Lu-Ying Yan, Li Tang, Yi-Wei Yin, Dai-Shuang Cheng, Jing Chen, Min Wang. Bioactivity and pharmacokinetics of two human serum albumin-thymosin alpha1-fusion proteins, rHSA-Talpha1 and rHSA-L-Talpha1, expressed in recombinant Pichia pastoris.
Cancer immunology, immunotherapy : CII.
2010 Sep; 59(9):1335-45. doi:
10.1007/s00262-010-0862-9
. [PMID: 20473755] - Ding Lu, Lisa A Peterson. Identification of furan metabolites derived from cysteine-cis-2-butene-1,4-dial-lysine cross-links.
Chemical research in toxicology.
2010 Jan; 23(1):142-51. doi:
10.1021/tx9003215
. [PMID: 20043645] - Ding Lu, Mathilde M Sullivan, Martin B Phillips, Lisa A Peterson. Degraded protein adducts of cis-2-butene-1,4-dial are urinary and hepatocyte metabolites of furan.
Chemical research in toxicology.
2009 Jun; 22(6):997-1007. doi:
10.1021/tx800377v
. [PMID: 19441776] - Bei Zhou, Li-Jun Wu, Lin-Hao Li, Shin-ichi Tashiro, Satoshi Onodera, Fumiaki Uchiumi, Takashi Ikejima. Silibinin protects against isoproterenol-induced rat cardiac myocyte injury through mitochondrial pathway after up-regulation of SIRT1.
Journal of pharmacological sciences.
2006 Dec; 102(4):387-95. doi:
10.1254/jphs.fpj06005x
. [PMID: 17170512] - Dong-sheng Chi, Wen-hua Ling, Jing Ma, Min Xia, Meng-jun Hou, Qing Wang, Hui-lian Zhu, Zhi-hong Tang, Xiao-ping Yu. [Relationship between paraoxonase 1 55 Met/Leu, paraoxonase 2 148 Ala/Gly genetic polymorphisms and coronary artery disease].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics.
2006 Jun; 23(3):289-93. doi:
. [PMID: 16767666]
- Choua C Vu, Lisa A Peterson. Synthesis of a 2'-deoxyguanosine adduct of cis-2-butene-1,4-dial, a reactive metabolite of furan.
Chemical research in toxicology.
2005 Jun; 18(6):1012-7. doi:
10.1021/tx049647d
. [PMID: 15962936] - Dan Meng, Xiang-Jian Chen, Yun-Yun Bian, Ping Li, Di Yang, Ji-Nan Zhang. Effect of astragalosides on intracellular calcium overload in cultured cardiac myocytes of neonatal rats.
The American journal of Chinese medicine.
2005; 33(1):11-20. doi:
10.1142/s0192415x05002618
. [PMID: 15844829] - A Chandra, S K Srivastava. A synthesis of 4-hydroxy-2-trans-nonenal and 4-(3H) 4-hydroxy-2-trans-nonenal.
Lipids.
1997 Jul; 32(7):779-82. doi:
10.1007/s11745-997-0100-6
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