Methyl clofenapate (BioDeep_00000841790)

   


代谢物信息卡片


Methyl clofenapate

化学式: C17H17ClO3 (304.0866)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)(C(=O)OC)OC1=CC=C(C=C1)C2=CC=C(C=C2)Cl
InChI: InChI=1S/C17H17ClO3/c1-17(2,16(19)20-3)21-15-10-6-13(7-11-15)12-4-8-14(18)9-5-12/h4-11H,1-3H3

描述信息

D057847 - Lipid Regulating Agents > D000960 - Hypolipidemic Agents
D009676 - Noxae > D000963 - Antimetabolites

同义名列表

1 个代谢物同义名

Methyl clofenapate



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • L Jackson, W Wahli, L Michalik, S A Watson, T Morris, K Anderton, D R Bell, J A Smith, C J Hawkey, A J Bennett. Potential role for peroxisome proliferator activated receptor (PPAR) in preventing colon cancer. Gut. 2003 Sep; 52(9):1317-22. doi: 10.1136/gut.52.9.1317. [PMID: 12912864]
  • N J Plant, N J Horley, M Dickins, S Hasmall, C R Elcombe, D R Bell. The coordinate regulation of DNA synthesis and suppression of apoptosis is differentially regulated by the liver growth agents, phenobarbital and methylclofenapate. Carcinogenesis. 1998 Sep; 19(9):1521-7. doi: 10.1093/carcin/19.9.1521. [PMID: 9771920]
  • N J Plant, N J Horley, R L Savory, C R Elcombe, T J Gray, D R Bell. The peroxisome proliferators are hepatocyte mitogens in chemically-defined media: glucocorticoid-induced PPAR alpha is linked to peroxisome proliferator mitogenesis. Carcinogenesis. 1998 May; 19(5):925-31. doi: 10.1093/carcin/19.5.925. [PMID: 9635884]
  • C R Elcombe, D R Bell, E Elias, S C Hasmall, N J Plant. Peroxisome proliferators: species differences in response of primary hepatocyte cultures. Annals of the New York Academy of Sciences. 1996 Dec; 804(?):628-35. doi: 10.1111/j.1749-6632.1996.tb18649.x. [PMID: 8993577]
  • D R Bell, R G Bars, C R Elcombe. Differential tissue-specific expression and induction of cytochrome P450IVA1 and acyl-CoA oxidase. European journal of biochemistry. 1992 Jun; 206(3):979-86. doi: 10.1111/j.1432-1033.1992.tb17009.x. [PMID: 1376690]
  • D R Bell, C R Elcombe. Regulation of differentially spliced transcripts of acyl-CoA oxidase in the rat. Biochimica et biophysica acta. 1991 Oct; 1090(2):211-5. doi: 10.1016/0167-4781(91)90103-s. [PMID: 1932112]
  • B M Elliott, C R Elcombe. Lack of DNA damage or lipid peroxidation measured in vivo in the rat liver following treatment with peroxisomal proliferators. Carcinogenesis. 1987 Sep; 8(9):1213-8. doi: 10.1093/carcin/8.9.1213. [PMID: 3621460]
  • J K Reed, M A Raftery. Properties of the tetrodotoxin binding component in plasma membranes isolated from Electrophorus electricus. Biochemistry. 1976 Mar; 15(5):944-53. doi: 10.1021/bi00650a002. [PMID: 3213]
  • D N Brindley, M Bowley. Drugs affecting the synthesis of glycerides and phospholipids in rat liver. The effects of clofibrate, halofenate, fenfluramine, amphetamine, cinchocaine, chlorpromazine, demethylimipramine, mepyramine and some of their derivatives. The Biochemical journal. 1975 Jun; 148(3):461-9. doi: 10.1042/bj1480461. [PMID: 1200988]
  • M C Stone, J M Thorp, J S Wain. Experimental and clinical evaluation of two 'Atromid-S' analogues in relation to their differential modes of action. Advances in experimental medicine and biology. 1975; 63(?):151-65. doi: 10.1007/978-1-4684-3258-9_10. [PMID: 173146]
  • J K Reddy, T P Krishnakantha, M S Rao. Microbody (peroxisome) proliferation in mouse kidney induced by methyl clofenapate. Virchows Archiv. B, Cell pathology. 1975; 17(4):295-306. doi: 10.1007/bf02912856. [PMID: 806162]