Carbamimidothioic acid, methyl ester (BioDeep_00000841750)
代谢物信息卡片
化学式: C2H6N2S (90.0251676)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CSC(=N)N
InChI: InChI=1S/C2H6N2S/c1-5-2(3)4/h1H3,(H3,3,4)
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Ashwani Kumar Sharma, Anmoldeep Kaur, Tajpreet Kaur, Sarabjit Kaur, Devendra Pathak, Amrit Pal Singh. Ameliorative role of inducible nitric oxide synthase inhibitors against sodium arsenite-induced renal and hepatic dysfunction in rats.
Drug and chemical toxicology.
2022 Sep; 45(5):2255-2261. doi:
10.1080/01480545.2021.1926109
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Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040
. [PMID: 33910017] - Honghong Xing, Lijun An, Ziteng Song, Shanshan Li, Huimei Wang, Chunyan Wang, Jie Zhang, Muhetaer Tuerhong, Munira Abudukeremu, Dihua Li, Dongho Lee, Jing Xu, Namrita Lall, Yuanqiang Guo. Anti-Inflammatory ent-Kaurane Diterpenoids from Isodon serra.
Journal of natural products.
2020 10; 83(10):2844-2853. doi:
10.1021/acs.jnatprod.9b01281
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Experimental gerontology.
2017 10; 97(?):38-48. doi:
10.1016/j.exger.2017.07.016
. [PMID: 28757113] - Yan-Yuen Poon, Ching-Yi Tsai, Chung-Dar Cheng, Alice Y W Chang, Samuel H H Chan. Endogenous nitric oxide derived from NOS I or II in thoracic spinal cord exerts opposing tonic modulation on sympathetic vasomotor tone via disparate mechanisms in anesthetized rats.
American journal of physiology. Heart and circulatory physiology.
2016 09; 311(3):H555-62. doi:
10.1152/ajpheart.00246.2016
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Anatomical record (Hoboken, N.J. : 2007).
2016 Feb; 299(2):246-55. doi:
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Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova.
2015 Aug; 101(8):921-8. doi:
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Connective tissue research.
2014 Oct; 55(5-6):367-77. doi:
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Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.].
2013 May; 13(3):225-9. doi:
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Naunyn-Schmiedeberg's archives of pharmacology.
2012 Nov; 385(11):1127-39. doi:
10.1007/s00210-012-0789-0
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Nitric oxide : biology and chemistry.
2012 Oct; 27(3):137-42. doi:
10.1016/j.niox.2012.06.005
. [PMID: 22743255] - Zeki Ilker Kunak, Enis Macit, Hakan Yaren, Halil Yaman, Erdinc Cakir, Ibrahim Aydin, Turker Turker, Yasemin Gulcan Kurt, Ayhan Ozcan, Bulent Uysal, Salim Isbilir, Emin Ozgur Akgul, Tuncer Cayci, Ahmet Korkmaz, Levent Kenar. Protective effects of melatonin and S-methylisothiourea on mechlorethamine induced nephrotoxicity.
The Journal of surgical research.
2012 Jun; 175(1):e17-23. doi:
10.1016/j.jss.2011.11.002
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Journal of molecular histology.
2012 Jun; 43(3):351-60. doi:
10.1007/s10735-012-9397-z
. [PMID: 22374168] - Xiaowei Nie, Shasha Song, Lei Zhang, Zhaoping Qiu, Shuai Shi, Yun Liu, Lan Yao, Daling Zhu. 15-Hydroxyeicosatetraenoic acid (15-HETE) protects pulmonary artery smooth muscle cells from apoptosis via inducible nitric oxide synthase (iNOS) pathway.
Prostaglandins & other lipid mediators.
2012 Jan; 97(1-2):50-9. doi:
10.1016/j.prostaglandins.2011.11.003
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Brain research.
2011 Oct; 1417(?):137-45. doi:
10.1016/j.brainres.2011.08.042
. [PMID: 21907329] - Yesim Oztas, Bulent Uysal, Umit Kaldirim, Yavuz Poyrazoglu, Mehmet Yasar, Tuncer Cayci, Yavuz Cekli, Serdar Sadir, Mehmet Ozler, Turgut Topal, Sukru Oter, Ahmet Korkmaz. Inhibition of iNOS reduces the therapeutic effects of ozone in acute necrotizing pancreatitis: an in vivo animal study.
Scandinavian journal of clinical and laboratory investigation.
2011 Sep; 71(5):370-7. doi:
10.3109/00365513.2011.572183
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Nitric oxide : biology and chemistry.
2010 Dec; 23(4):284-8. doi:
10.1016/j.niox.2010.08.004
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Nitric oxide : biology and chemistry.
2010 Jan; 22(1):1-10. doi:
10.1016/j.niox.2009.10.002
. [PMID: 19836458] - Laura M López-Sánchez, Fernando J Corrales, Montserrat Barcos, Isabel Espejo, Juan R Muñoz-Castañeda, Antonio Rodríguez-Ariza. Inhibition of nitric oxide synthesis during induced cholestasis ameliorates hepatocellular injury by facilitating S-nitrosothiol homeostasis.
Laboratory investigation; a journal of technical methods and pathology.
2010 Jan; 90(1):116-27. doi:
10.1038/labinvest.2009.104
. [PMID: 19806079] - Jie Peng, Yang-Kai Wang, Li-Gang Wang, Wen-Jun Yuan, Ding-Feng Su, Xin Ni, Xiao-Ming Deng, Wei-Zhong Wang. Sympathoinhibitory mechanism of moxonidine: role of the inducible nitric oxide synthase in the rostral ventrolateral medulla.
Cardiovascular research.
2009 Nov; 84(2):283-91. doi:
10.1093/cvr/cvp202
. [PMID: 19535378] - Agostino Virdis, Rocchina Colucci, Matteo Fornai, Antonio Polini, Elena Daghini, Emiliano Duranti, Narcisa Ghisu, Daniele Versari, Angela Dardano, Corrado Blandizzi, Stefano Taddei, Mario Del Tacca, Fabio Monzani. Inducible nitric oxide synthase is involved in endothelial dysfunction of mesenteric small arteries from hypothyroid rats.
Endocrinology.
2009 Feb; 150(2):1033-42. doi:
10.1210/en.2008-1112
. [PMID: 18927216] - Silvia Bertuglia. Intermittent hypoxia modulates nitric oxide-dependent vasodilation and capillary perfusion during ischemia-reperfusion-induced damage.
American journal of physiology. Heart and circulatory physiology.
2008 Apr; 294(4):H1914-22. doi:
10.1152/ajpheart.01371.2007
. [PMID: 18296561] - Ahmet Guven, Bulent Uysal, Ozgur Akgul, Hakan Cermik, Gokhan Gundogdu, Ilhami Surer, Haluk Ozturk, Ahmet Korkmaz. Scavenging of peroxynitrite reduces renal ischemia/reperfusion injury.
Renal failure.
2008; 30(7):747-54. doi:
10.1080/08860220802213039
. [PMID: 18704824] - Yung Hsiang Hsu, Bang Gee Hsu, Hsing I Chen. Malignant alterations following early blockade of nitric oxide synthase in hypertensive rats.
The Chinese journal of physiology.
2007 Dec; 50(6):283-93. doi:
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. [PMID: 18442011] - Shashi Bhushan, Ajay Kumar, Fayaz Malik, Samar Singh Andotra, Vijay Kumar Sethi, Indu Pal Kaur, Subhash Chandra Taneja, Ghulam Nabi Qazi, Jaswant Singh. A triterpenediol from Boswellia serrata induces apoptosis through both the intrinsic and extrinsic apoptotic pathways in human leukemia HL-60 cells.
Apoptosis : an international journal on programmed cell death.
2007 Oct; 12(10):1911-26. doi:
10.1007/s10495-007-0105-5
. [PMID: 17636381] - V D Pinto, G J S Cutini, C L Sartório, A S Paigel, D V Vassallo, I Stefanon. Enhanced beta-adrenergic response in rat papillary muscle by inhibition of inducible nitric oxide synthase after myocardial infarction.
Acta physiologica (Oxford, England).
2007 Jun; 190(2):111-7. doi:
10.1111/j.1748-1716.2007.01684.x
. [PMID: 17394569] - Suzanne Heemskerk, Arianne van Koppen, Luc van den Broek, Geert J M Poelen, Alfons C Wouterse, Henry B P M Dijkman, Frans G M Russel, Rosalinde Masereeuw. Nitric oxide differentially regulates renal ATP-binding cassette transporters during endotoxemia.
Pflugers Archiv : European journal of physiology.
2007 May; 454(2):321-34. doi:
10.1007/s00424-007-0210-x
. [PMID: 17285300] - Chain Fa Su, Fwu Lin Yang, Hsing I Chen. Inhibition of inducible nitric oxide synthase attenuates acute endotoxin-induced lung injury in rats.
Clinical and experimental pharmacology & physiology.
2007 Apr; 34(4):339-46. doi:
10.1111/j.1440-1681.2007.04553.x
. [PMID: 17324147] - Ch Bopp, R Gust, F Taut, A Gries, E Martin, A Klein. Responsiveness to inhaled NO in isolated-perfused lungs from endotoxin-challenged rats is dependent on endogenous nitrite/nitrate synthesis.
European journal of anaesthesiology.
2007 Apr; 24(4):362-9. doi:
10.1017/s0265021506001463
. [PMID: 17094870] - G L Tipoe, T M Leung, E Liong, H So, K M Leung, T Y H Lau, W M Tom, M L Fung, S T Fan, A A Nanji. Inhibitors of inducible nitric oxide (NO) synthase are more effective than an NO donor in reducing carbon-tetrachloride induced acute liver injury.
Histology and histopathology.
2006 11; 21(11):1157-65. doi:
10.14670/hh-21.1157
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Die Pharmazie.
2006 Jun; 61(6):568-70. doi:
"
. [PMID: 16826982] - Giuseppe Esposito, Daniele De Filippis, Carla Cirillo, Giovanni Sarnelli, Rosario Cuomo, Teresa Iuvone. The astroglial-derived S100beta protein stimulates the expression of nitric oxide synthase in rodent macrophages through p38 MAP kinase activation.
Life sciences.
2006 May; 78(23):2707-15. doi:
10.1016/j.lfs.2005.10.023
. [PMID: 16376947] - Cheng-Dean Shih, Jih-Jung Chen, Hsinn-Hsing Lee. Activation of nitric oxide signaling pathway mediates hypotensive effect of Muntingia calabura L. (Tiliaceae) leaf extract.
The American journal of Chinese medicine.
2006; 34(5):857-72. doi:
10.1142/s0192415x0600434x
. [PMID: 17080550] - Georg Baumgarten, Pascal Knuefermann, Gerrit Schuhmacher, Volker Vervölgyi, Joscha von Rappard, Ulrike Dreiner, Klaus Fink, Chryso Djoufack, Andreas Hoeft, Christian Grohé, A A Knowlton, Rainer Meyer. Toll-like receptor 4, nitric oxide, and myocardial depression in endotoxemia.
Shock (Augusta, Ga.).
2006 Jan; 25(1):43-9. doi:
10.1097/01.shk.0000196498.57306.a6
. [PMID: 16369185] - N E Maksimovich. [Platelet aggregation in modulation of the pathway L-arginine-NO in rats with cerebral ischemia].
Patologicheskaia fiziologiia i eksperimental'naia terapiia.
2005 Oct; ?(4):14-5. doi:
NULL
. [PMID: 16408659] - Chia-Chi Lee, Nien-Tseng Lin, Yung Hsing Hsu, Hsing I Chen. Inducible nitric oxide synthase inhibition potentiates multiple organ dysfunction induced by endotoxin in conscious rats.
Journal of cardiovascular pharmacology.
2005 May; 45(5):396-403. doi:
10.1097/01.fjc.0000157438.72483.ae
. [PMID: 15821434] - Carmem Luíza Sartório, Valber Dias Pinto, Gustavo Julio de Salles Cutini, Dalton Valentim Vassallo, Ivanita Stefanon. Effects of inducible nitric oxide synthase inhibition on the rat tail vascular bed reactivity three days after myocardium infarction.
Journal of cardiovascular pharmacology.
2005 Apr; 45(4):321-6. doi:
10.1097/01.fjc.0000156822.58081.be
. [PMID: 15772520] - Yoshikuni Kimura, Yoshitaka Hirooka, Yoji Sagara, Koji Ito, Takuya Kishi, Hiroaki Shimokawa, Akira Takeshita, Kenji Sunagawa. Overexpression of inducible nitric oxide synthase in rostral ventrolateral medulla causes hypertension and sympathoexcitation via an increase in oxidative stress.
Circulation research.
2005 Feb; 96(2):252-60. doi:
10.1161/01.res.0000152965.75127.9d
. [PMID: 15591232] - Lee-Wei Chen, Bonnie Hwang, Jyh-Seng Wang, Jin-Shyr Chen, Ching-Mei Hsu. Hypertonic saline-enhanced postburn gut barrier failure is reversed by inducible nitric oxide synthase inhibition.
Critical care medicine.
2004 Dec; 32(12):2476-84. doi:
10.1097/01.ccm.0000147831.07329.32
. [PMID: 15599154] - Lee-Wei Chen, Bonnie Hwang, Wei-Jung Chang, Jyh-Seng Wang, Jin-Shyr Chen, Ching-Mei Hsu. Inducible nitric oxide synthase inhibitor reverses exacerbating effects of hypertonic saline on lung injury in burn.
Shock (Augusta, Ga.).
2004 Nov; 22(5):472-7. doi:
10.1097/01.shk.0000140304.71215.f7
. [PMID: 15489641] - Toshiko Tanaka, Hiroaki Sato, Toshiro Kita, Noriyuki Tanaka. Involvement of inducible nitric oxide synthase in renal failure after mild hemorrhage.
Legal medicine (Tokyo, Japan).
2004 Oct; 6(4):203-12. doi:
10.1016/j.legalmed.2004.05.002
. [PMID: 15363445] - Bin Zheng, Lin-Sheng Cao, Qiu-Tang Zeng, Xiang Wang, Da-Zhu Li, Yu-Hua Liao. Inhibition of NOS2 ameliorates cardiac remodeling, improves heart function after myocardial infarction in rats.
Basic research in cardiology.
2004 Jul; 99(4):264-71. doi:
10.1007/s00395-004-0470-y
. [PMID: 15221344] - R P Korolkiewicz, J Sein-Anand, J Ruczyński, P Rekowski, L Bieniaszewski, Z Chodorowski, J Petrusewicz, M Ujda, J Dabkowski, M Bitel, S Kato, K Takeuchi. The role and interactions of nitric oxide (NO), carbon monoxide (CO), and prostanoids in the pathogenesis of postoperative ileus in rats.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract.
2004 Mar; 8(3):346-57. doi:
10.1016/j.gassur.2003.11.004
. [PMID: 15019933] - A Turan Isik, M Refik Mas, Bilgin Comert, Mehmet Yasar, Ahmet Korkmaz, Cemal Akay, Salih Deveci, Ilker Tasci, Nuket Mas, Yuksel Ates, I Hakki Kocar. The effect of combination therapy of hyperbaric oxygen, meropenem, and selective nitric oxide synthase inhibitor in experimental acute pancreatitis.
Pancreas.
2004 Jan; 28(1):53-7. doi:
10.1097/00006676-200401000-00008
. [PMID: 14707730] - Rosa A González-Polo, Germán Soler, Andrea Rodríguezmartín, Jose M Morán, José M Fuentes. Protection against MPP+ neurotoxicity in cerebellar granule cells by antioxidants.
Cell biology international.
2004; 28(5):373-80. doi:
10.1016/j.cellbi.2004.03.005
. [PMID: 15193280] - Lee-Wei Chen, Jyh-Seng Wang, Bonnie Hwang, Jin-Shyr Chen, Ching-Mei Hsu. Reversal of the effect of albumin on gut barrier function in burn by the inhibition of inducible isoform of nitric oxide synthase.
Archives of surgery (Chicago, Ill. : 1960).
2003 Nov; 138(11):1219-25. doi:
10.1001/archsurg.138.11.1219
. [PMID: 14609870] - Shoshiro Okada, Keiko Yokotani, Kunihiko Yokotani. Inducible nitric oxide synthase is involved in corticotropin-releasing hormone-mediated central sympatho-adrenal outflow in rats.
European journal of pharmacology.
2003 Sep; 477(2):95-100. doi:
10.1016/j.ejphar.2003.08.009
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Critical care medicine.
2003 Aug; 31(8):2170-7. doi:
10.1097/01.ccm.0000079605.28852.d0
. [PMID: 12973176] - Lionel Valenti, Jacques Mathieu, Yves Chancerelle, Maryse Levacher, Brigitte Chanaud, Martine De Sousa, Suzanne Strzalko, Anh Tuan Dinh-Xuan, Jean-Paul Giroud, Irène Florentin. Nitric oxide inhibits spleen cell proliferative response after burn injury by inducing cytostasis, apoptosis, and necrosis of activated T lymphocytes: role of the guanylate cyclase.
Cellular immunology.
2003 Jan; 221(1):50-63. doi:
10.1016/s0008-8749(03)00064-9
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American journal of physiology. Heart and circulatory physiology.
2002 Jul; 283(1):H339-45. doi:
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Clinical nutrition (Edinburgh, Scotland).
2002 Apr; 21(2):111-7. doi:
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Shock (Augusta, Ga.).
2002 Apr; 17(4):280-5. doi:
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American journal of respiratory and critical care medicine.
2001 Nov; 164(10 Pt 1):1890-5. doi:
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Pancreas.
2001 Oct; 23(3):296-301. doi:
10.1097/00006676-200110000-00011
. [PMID: 11590326] - X Xu, L X Cubeddu, A Malave. Expression of inducible nitric oxide synthase in primary culture of rat bladder smooth muscle cells by plasma from cyclophosphamide-treated rats.
European journal of pharmacology.
2001 Mar; 416(1-2):1-9. doi:
10.1016/s0014-2999(01)00846-9
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Naunyn-Schmiedeberg's archives of pharmacology.
2001 Mar; 363(3):353-7. doi:
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. [PMID: 11284451] - D Brandhorst, H Brandhorst, A Zwolinski, F Nahidi, R G Bretzel. Prevention of early islet graft failure by selective inducible nitric oxide synthase inhibitors after pig to nude rat intraportal islet transplantation.
Transplantation.
2001 Jan; 71(2):179-84. doi:
10.1097/00007890-200101270-00002
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The journal of extra-corporeal technology.
2000 Dec; 32(4):190-5. doi:
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Toxicology.
2000 Nov; 155(1-3):37-44. doi:
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Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology.
2000 Nov; 16(4):314-7. doi:
NULL
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Critical care medicine.
2000 Sep; 28(9):3257-67. doi:
10.1097/00003246-200009000-00022
. [PMID: 11008990] - C M Hsu, C H Liu, L W Chen. Nitric oxide synthase inhibitor ameliorates oral total parenteral nutrition-induced barrier dysfunction.
Shock (Augusta, Ga.).
2000 Feb; 13(2):135-9. doi:
10.1097/00024382-200013020-00007
. [PMID: 10670843] - C Mitaka, Y Hirata, Y Masaki, T Takei, K Yokoyama, T Imai. S-Methylisothiourea sulfate improves renal, but not hepatic dysfunction in canine endotoxic shock model.
Intensive care medicine.
2000 Jan; 26(1):117-24. doi:
10.1007/s001340050023
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