Erbstatin (BioDeep_00000841746)
代谢物信息卡片
Erbstatin
化学式: C9H9NO3 (179.05824040000002)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=C(C=C1O)C=CNC=O)O
InChI: InChI=1S/C9H9NO3/c11-6-10-4-3-7-5-8(12)1-2-9(7)13/h1-6,12-13H,(H,10,11)/b4-3+
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Thanos Ghelis, Gérard Bolbach, Gilles Clodic, Yvette Habricot, Emile Miginiac, Bruno Sotta, Emmanuelle Jeannette. Protein tyrosine kinases and protein tyrosine phosphatases are involved in abscisic acid-dependent processes in Arabidopsis seeds and suspension cells.
Plant physiology.
2008 Nov; 148(3):1668-80. doi:
10.1104/pp.108.124594. [PMID: 18768909] - Takeshi Kumazawa, Takaki Hiwasa, Masaki Takiguchi, Osamu Suzuki, Keizo Sato. Activation of Ras signaling pathways by pyrroloquinoline quinone in NIH3T3 mouse fibroblasts.
International journal of molecular medicine.
2007 May; 19(5):765-70. doi:
10.3892/ijmm.19.5.765. [PMID: 17390081] - Being-Sun Wung, Ming-Chun Hsu, Chun-Ching Wu, Chia-Wen Hsieh. Piceatannol upregulates endothelial heme oxygenase-1 expression via novel protein kinase C and tyrosine kinase pathways.
Pharmacological research.
2006 Feb; 53(2):113-22. doi:
10.1016/j.phrs.2005.09.006. [PMID: 16243536] - Qiusheng Tong, James D Stockand. Receptor tyrosine kinases mediate epithelial Na(+) channel inhibition by epidermal growth factor.
American journal of physiology. Renal physiology.
2005 Jan; 288(1):F150-61. doi:
10.1152/ajprenal.00261.2004. [PMID: 15454394] - Won-Hwan Park, Shin-Tak Joo, Kwan-Kyu Park, Young-Chae Chang, Cheorl-Ho Kim. Effects of the Geiji-Bokryung-Hwan on carrageenan-induced inflammation in mice and cyclooxygenase-2 in hepatoma cells of HepG2 and Hep3B.
Immunopharmacology and immunotoxicology.
2004 Feb; 26(1):103-12. doi:
10.1081/iph-120029948. [PMID: 15106735] - Andrew P Feranchak, Gordan Kilic, Paul A Wojtaszek, Ishtiaq Qadri, J Gregory Fitz. Volume-sensitive tyrosine kinases regulate liver cell volume through effects on vesicular trafficking and membrane Na+ permeability.
The Journal of biological chemistry.
2003 Nov; 278(45):44632-8. doi:
10.1074/jbc.m301958200. [PMID: 12939281] - T Watanabe, R Pakala, T Katagiri, C R Benedict. Lipid peroxidation product 4-hydroxy-2-nonenal acts synergistically with serotonin in inducing vascular smooth muscle cell proliferation.
Atherosclerosis.
2001 Mar; 155(1):37-44. doi:
10.1016/s0021-9150(00)00526-8. [PMID: 11223424] - D Haynes-Johnson, M T Lai, C Campen, S Palmer. Diverse effects of tyrosine kinase inhibitors on follicle-stimulating hormone-stimulated estradiol and progesterone production from rat granulosa cells in serum-containing medium and serum-free medium containing epidermal growth factor.
Biology of reproduction.
1999 Jul; 61(1):147-53. doi:
10.1095/biolreprod61.1.147. [PMID: 10377043] - B S McIntyre, P W Sylvester. Genistein and erbstatin inhibition of normal mammary epithelial cell proliferation is associated with EGF-receptor down-regulation.
Cell proliferation.
1998 Feb; 31(1):35-46. doi:
10.1046/j.1365-2184.1998.00108.x. [PMID: 9666817] - F Watson, L Gasmi, S W Edwards. Stimulation of intracellular Ca2+ levels in human neutrophils by soluble immune complexes. Functional activation of FcgammaRIIIb during priming.
The Journal of biological chemistry.
1997 Jul; 272(29):17944-51. doi:
10.1074/jbc.272.29.17944. [PMID: 9218419] - A Ota, S Yoshida, T Nomura, S Matsui, Y Hagino, K Umezawa, S Katoh, T Nagatsu. Tetrahydrobiopterin biosynthesis enhanced by lipopolysaccharide stimulation in murine neuroblastoma cell line N1E-115.
Journal of neurochemistry.
1996 Dec; 67(6):2540-8. doi:
10.1046/j.1471-4159.1996.67062540.x. [PMID: 8931488] - T Tsakiridis, C Taha, S Grinstein, A Klip. Insulin activates a p21-activated kinase in muscle cells via phosphatidylinositol 3-kinase.
The Journal of biological chemistry.
1996 Aug; 271(33):19664-7. doi:
10.1074/jbc.271.33.19664. [PMID: 8702668] - J C Jonas, T D Plant, P Gilon, P Detimary, M Nenquin, J C Henquin. Multiple effects and stimulation of insulin secretion by the tyrosine kinase inhibitor genistein in normal mouse islets.
British journal of pharmacology.
1995 Feb; 114(4):872-80. doi:
10.1111/j.1476-5381.1995.tb13285.x. [PMID: 7773549] - T Kusunoki, S Tsuruta, H Higashi, S Hosoi, D Hata, K Sugie, M Mayumi, H Mikawa. Involvement of CD11b/CD18 in enhanced neutrophil adhesion by Fc gamma receptor stimulation.
Journal of leukocyte biology.
1994 Jun; 55(6):735-42. doi:
10.1002/jlb.55.6.735. [PMID: 7910840] - A M Thompson, G W Rewcastle, M Tercel, E M Dobrusin, D W Fry, A J Kraker, W A Denny. Tyrosine kinase inhibitors. 1. Structure-activity relationships for inhibition of epidermal growth factor receptor tyrosine kinase activity by 2,3-dihydro-2-thioxo-1H-indole-3-alkanoic acids and 2,2'-dithiobis(1H-indole-3-alkanoic acids).
Journal of medicinal chemistry.
1993 Aug; 36(17):2459-69. doi:
10.1021/jm00069a003. [PMID: 8355247] - D Sugata, K Yamashita, K Umezawa. Inhibition of serum-induced M-phase progression by a tyrosine kinase inhibitor, erbstatin.
Biochemical and biophysical research communications.
1993 Jul; 194(1):239-45. doi:
10.1006/bbrc.1993.1810. [PMID: 8333839] - K Yasui, E L Becker, R I Sha'afi. Lipopolysaccharide in combination with serum potentiates the stimulated activity of phospholipase D in human neutrophils via CD14.
Membrane biochemistry.
1993 Apr; 10(2):81-9. doi:
10.3109/09687689309150255. [PMID: 7689689] - M Gaudry, A C Caon, C Gilbert, S Lille, P H Naccache. Evidence for the involvement of tyrosine kinases in the locomotory responses of human neutrophils.
Journal of leukocyte biology.
1992 Feb; 51(2):103-8. doi:
10.1002/jlb.51.2.103. [PMID: 1385557] - N Takekura, W Yasui, E Kyo, K Yoshida, T Kameda, Y Kitadai, K Abe, K Umezawa, E Tahara. Effects of tyrosine kinase inhibitor, erbstatin, on cell growth and growth-factor/receptor gene expression in human gastric carcinoma cells.
International journal of cancer.
1991 Apr; 47(6):938-42. doi:
10.1002/ijc.2910470626. [PMID: 1849125] - K Umezawa, K Tanaka, T Hori, S Abe, R Sekizawa, M Imoto. Induction of morphological change by tyrosine kinase inhibitors in Rous sarcoma virus-transformed rat kidney cells.
FEBS letters.
1991 Feb; 279(1):132-6. doi:
10.1016/0014-5793(91)80267-7. [PMID: 1704855] - K Umezawa. [Inhibitors of oncogene product functions].
Gan to kagaku ryoho. Cancer & chemotherapy.
1990 Mar; 17(3 Pt 1):315-21. doi:
NULL. [PMID: 2155583] - K Umezawa, T Hori, H Tajima, M Imoto, K Isshiki, T Takeuchi. Inhibition of epidermal growth factor-induced DNA synthesis by tyrosine kinase inhibitors.
FEBS letters.
1990 Jan; 260(2):198-200. doi:
10.1016/0014-5793(90)80102-o. [PMID: 2298299] - M Imoto, K Umezawa, T Sawa, T Takeuchi, H Umezawa. In situ inhibition of tyrosine protein kinase by erbstatin.
Biochemistry international.
1987 Nov; 15(5):989-95. doi:
NULL. [PMID: 3501720] - M Imoto, K Umezawa, K Komuro, T Sawa, T Takeuchi, H Umezawa. Antitumor activity of erbstatin, a tyrosine protein kinase inhibitor.
Japanese journal of cancer research : Gann.
1987 Apr; 78(4):329-32. doi:
. [PMID: 3108212]