N-Tert-butyl-alpha-phenylnitrone (BioDeep_00000841706)
代谢物信息卡片
n-tert-butyl-n-[(e)-phenylmethylene]amine oxide
化学式: C11H15NO (177.115358)
中文名称: N-叔丁基-а-苯基硝酮
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)(C)[N+](=CC1=CC=CC=C1)[O-]
InChI: InChI=1S/C11H15NO/c1-11(2,3)12(13)9-10-7-5-4-6-8-10/h4-9H,1-3H3/b12-9-
描述信息
D002491 - Central Nervous System Agents > D018696 - Neuroprotective Agents
D020011 - Protective Agents
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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文献列表
- Qing-Lin Ye, Da-Ming Wang, Xin Wang, Zhi-Qiang Zhang, Qi-Xing Tian, Shi-Yao Feng, Zhi-Hui Zhang, De-Xin Yu, De-Mao Ding, Dong-Dong Xie. Sirt1 inhibits kidney stones formation by attenuating calcium oxalate-induced cell injury.
Chemico-biological interactions.
2021 Sep; 347(?):109605. doi:
10.1016/j.cbi.2021.109605. [PMID: 34333021] - Beatriz Chamorro, David García-Vieira, Daniel Diez-Iriepa, Estíbaliz Garagarza, Mourad Chioua, Dimitra Hadjipavlou-Litina, Francisco López-Muñoz, José Marco-Contelles, María Jesús Oset-Gasque. Synthesis, Neuroprotection, and Antioxidant Activity of 1,1'-Biphenylnitrones as α-Phenyl-N-tert-butylnitrone Analogues in In Vitro Ischemia Models.
Molecules (Basel, Switzerland).
2021 Feb; 26(4):. doi:
10.3390/molecules26041127. [PMID: 33672652] - Donny W H Merkx, Lorenz Plankensteiner, Yafei Yu, Peter A Wierenga, Marie Hennebelle, John P M Van Duynhoven. Evaluation of PBN spin-trapped radicals as early markers of lipid oxidation in mayonnaise.
Food chemistry.
2021 Jan; 334(?):127578. doi:
10.1016/j.foodchem.2020.127578. [PMID: 32721836] - Beatriz Chamorro, Daniel Diez-Iriepa, Belén Merás-Sáiz, Mourad Chioua, David García-Vieira, Isabel Iriepa, Dimitra Hadjipavlou-Litina, Francisco López-Muñoz, Ricardo Martínez-Murillo, Daniel Gonzàlez-Nieto, Israel Fernández, José Marco-Contelles, María Jesús Oset-Gasque. Synthesis, antioxidant properties and neuroprotection of α-phenyl-tert-butylnitrone derived HomoBisNitrones in in vitro and in vivo ischemia models.
Scientific reports.
2020 08; 10(1):14150. doi:
10.1038/s41598-020-70690-y. [PMID: 32843666] - Alicia Jiménez-Almarza, Daniel Diez-Iriepa, Mourad Chioua, Beatriz Chamorro, Isabel Iriepa, Ricardo Martínez-Murillo, Dimitra Hadjipavlou-Litina, María Jesús Oset-Gasque, José Marco-Contelles. Synthesis, neuroprotective and antioxidant capacity of PBN-related indanonitrones.
Bioorganic chemistry.
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Journal of the American College of Cardiology.
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2006 Dec; 195(6):1707-14. doi:
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Analytical biochemistry.
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Environmental toxicology and chemistry.
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Toxicological sciences : an official journal of the Society of Toxicology.
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Experimental gerontology.
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Toxicology.
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Bioorganic & medicinal chemistry letters.
2005 Jun; 15(12):3012-5. doi:
10.1016/j.bmcl.2005.04.043. [PMID: 15896960] - Young-Sook Kang, Kyeong-Eun Lee, Na-Young Lee, Tetsuya Terasaki. Donepezil, tacrine and alpha-phenyl-n-tert-butyl nitrone (PBN) inhibit choline transport by conditionally immortalized rat brain capillary endothelial cell lines (TR-BBB).
Archives of pharmacal research.
2005 Apr; 28(4):443-50. doi:
10.1007/bf02977674. [PMID: 15918518] - Joaquín Velasco, Mogens L Andersen, Leif H Skibsted. Electron spin resonance spin trapping for analysis of lipid oxidation in oils: inhibiting effect of the spin trap alpha-phenyl-N-tert-butylnitrone on lipid oxidation.
Journal of agricultural and food chemistry.
2005 Mar; 53(5):1328-36. doi:
10.1021/jf049051w. [PMID: 15740002] - H Hirano, Y Tabuchi, T Kondo, Q-L Zhao, R Ogawa, Z-G Cui, L B Feril, S Kanayama. Analysis of gene expression in apoptosis of human lymphoma U937 cells induced by heat shock and the effects of alpha-phenyl N-tert-butylnitrone (PBN) and its derivatives.
Apoptosis : an international journal on programmed cell death.
2005 Mar; 10(2):331-40. doi:
10.1007/s10495-005-0807-5. [PMID: 15843894] - Chang Won Choi, Jong Hee Hwang, Yun Sil Chang, Son Moon Shin, Won Soon Park, Munhyang Lee. Effects of alpha-phenyl-N-tert-butyl nitrone (PBN)on brain cell membrane function and energy metabolism during transient global cerebral hypoxia-ischemia and reoxygenation-reperfusion in newborn piglets.
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Brain research.
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Brain research.
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Drug metabolism and drug interactions.
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Shock (Augusta, Ga.).
2002 Mar; 17(3):210-6. doi:
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Arthritis research.
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