Thyronamine (BioDeep_00000840973)
代谢物信息卡片
Thyronamine
化学式: C14H15NO2 (229.1103)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=CC=C1CCN)OC2=CC=C(C=C2)O
InChI: InChI=1S/C14H15NO2/c15-10-9-11-1-5-13(6-2-11)17-14-7-3-12(16)4-8-14/h1-8,16H,9-10,15H2
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Lorenza Bellusci, Massimiliano Runfola, Vittoria Carnicelli, Simona Sestito, Federica Fulceri, Filippo Santucci, Paola Lenzi, Francesco Fornai, Simona Rapposelli, Nicola Origlia, Riccardo Zucchi, Grazia Chiellini. Endogenous 3-Iodothyronamine (T1AM) and Synthetic Thyronamine-like Analog SG-2 Act as Novel Pleiotropic Neuroprotective Agents Through the Modulation of SIRT6.
Molecules (Basel, Switzerland).
2020 Feb; 25(5):. doi:
10.3390/molecules25051054. [PMID: 32110992] - Josef Köhrle. Thyroid Hormones and Derivatives: Endogenous Thyroid Hormones and Their Targets.
Methods in molecular biology (Clifton, N.J.).
2018; 1801(?):85-104. doi:
10.1007/978-1-4939-7902-8_9. [PMID: 29892819] - Carolin Stephanie Hoefig, Riccardo Zucchi, Josef Köhrle. Thyronamines and Derivatives: Physiological Relevance, Pharmacological Actions, and Future Research Directions.
Thyroid : official journal of the American Thyroid Association.
2016 12; 26(12):1656-1673. doi:
10.1089/thy.2016.0178. [PMID: 27650974] - Rosalba Senese, Federica Cioffi, Pieter de Lange, Fernando Goglia, Antonia Lanni. Thyroid: biological actions of 'nonclassical' thyroid hormones.
The Journal of endocrinology.
2014 May; 221(2):R1-12. doi:
10.1530/joe-13-0573. [PMID: 24464019] - Carolin S Hoefig, Kostja Renko, Susanne Piehl, Thomas S Scanlan, Mariarita Bertoldi, Thomas Opladen, Georg Friedrich Hoffmann, Jeannette Klein, Oliver Blankenstein, Ulrich Schweizer, Josef Köhrle. Does the aromatic L-amino acid decarboxylase contribute to thyronamine biosynthesis?.
Molecular and cellular endocrinology.
2012 Feb; 349(2):195-201. doi:
10.1016/j.mce.2011.10.024. [PMID: 22061622] - Gunnar Kleinau, Juliane Pratzka, Daniela Nürnberg, Annette Grüters, Dagmar Führer-Sakel, Heiko Krude, Josef Köhrle, Torsten Schöneberg, Heike Biebermann. Differential modulation of Beta-adrenergic receptor signaling by trace amine-associated receptor 1 agonists.
PloS one.
2011; 6(10):e27073. doi:
10.1371/journal.pone.0027073. [PMID: 22073124] - Hung-Yun Lin, Faith B Davis, Mary K Luidens, Shaker A Mousa, James H Cao, Min Zhou, Paul J Davis. Molecular basis for certain neuroprotective effects of thyroid hormone.
Frontiers in molecular neuroscience.
2011; 4(?):29. doi:
10.3389/fnmol.2011.00029. [PMID: 22016721] - Alessandro Saba, Grazia Chiellini, Sabina Frascarelli, Maja Marchini, Sandra Ghelardoni, Andrea Raffaelli, Massimo Tonacchera, Paolo Vitti, Thomas S Scanlan, Riccardo Zucchi. Tissue distribution and cardiac metabolism of 3-iodothyronamine.
Endocrinology.
2010 Oct; 151(10):5063-73. doi:
10.1210/en.2010-0491. [PMID: 20739399] - M T Ackermans, L P Klieverik, P Ringeling, E Endert, A Kalsbeek, E Fliers. An online solid-phase extraction-liquid chromatography-tandem mass spectrometry method to study the presence of thyronamines in plasma and tissue and their putative conversion from 13C6-thyroxine.
The Journal of endocrinology.
2010 Sep; 206(3):327-34. doi:
10.1677/joe-10-0060. [PMID: 20603264] - Lars P Klieverik, Ewout Foppen, Mariëtte T Ackermans, Mireille J Serlie, Hans P Sauerwein, Thomas S Scanlan, David K Grandy, Eric Fliers, Andries Kalsbeek. Central effects of thyronamines on glucose metabolism in rats.
The Journal of endocrinology.
2009 Jun; 201(3):377-86. doi:
10.1677/joe-09-0043. [PMID: 19273499] - Alexandra G Ianculescu, Kathleen M Giacomini, Thomas S Scanlan. Identification and characterization of 3-iodothyronamine intracellular transport.
Endocrinology.
2009 Apr; 150(4):1991-9. doi:
10.1210/en.2008-1339. [PMID: 19074582] - L J Braulke, M Klingenspor, A DeBarber, S C Tobias, D K Grandy, T S Scanlan, G Heldmaier. 3-Iodothyronamine: a novel hormone controlling the balance between glucose and lipid utilisation.
Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology.
2008 Feb; 178(2):167-77. doi:
10.1007/s00360-007-0208-x. [PMID: 17912534] - Maria Moreno, Pieter de Lange, Assunta Lombardi, Elena Silvestri, Antonia Lanni, Fernando Goglia. Metabolic effects of thyroid hormone derivatives.
Thyroid : official journal of the American Thyroid Association.
2008 Feb; 18(2):239-53. doi:
10.1089/thy.2007.0248. [PMID: 18279024] - Sing-Yung Wu, William L Green, Wen-Sheng Huang, Marguerite T Hays, Inder J Chopra. Alternate pathways of thyroid hormone metabolism.
Thyroid : official journal of the American Thyroid Association.
2005 Aug; 15(8):943-58. doi:
10.1089/thy.2005.15.943. [PMID: 16131336]
