2H-pyran (BioDeep_00000840968)
代谢物信息卡片
CHEBI:35592
化学式: C5H6O (82.0419)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C=CC=CO1
InChI: InChI=1S/C5H6O/c1-2-4-6-5-3-1/h1-4H,5H2
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 33090 - 砂仁: -
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Serena Fiorito, Chiara Collevecchio, Roberto Spogli, Francesco Epifano, Salvatore Genovese. Novel procedures for olive leaves extracts processing: Selective isolation of oleuropein and elenolic acid.
Food chemistry.
2024 Jul; 447(?):139038. doi:
10.1016/j.foodchem.2024.139038. [PMID: 38507946] - A Cervantes-Díaz, M Mateo-Miranda, N H Torrado-Cubero, J L Alonso-Prados, P Sandín-España. Stereoisomeric separation of the chiral herbicide profoxydim and residue method development in rice by QuEChERS and LC-MS/MS.
Food chemistry.
2024 Jun; 443(?):138536. doi:
10.1016/j.foodchem.2024.138536. [PMID: 38277930] - Young-Joon Park, Bo Eun Nam, Chung-Mo Park. Environmentally adaptive reshaping of plant photomorphogenesis by karrikin and strigolactone signaling.
Journal of integrative plant biology.
2024 May; 66(5):865-882. doi:
10.1111/jipb.13602. [PMID: 38116738] - Qiming Qiu, Shengchun Sun, Hao Yuan, Shiyi Zhang, Yuyan Feng, Fanghao Wang, Yihang Zhu, Mingchuan Zhou, Yixian Wang. Second near-infrared fluorescent Metal-Organic framework sensors for in vivo extracellular adenosine triphosphate monitoring.
Biosensors & bioelectronics.
2024 May; 251(?):116114. doi:
10.1016/j.bios.2024.116114. [PMID: 38354495] - Xiuwei Shen, Chen Chen, Congcong Wen, Shuaishuai Yu, Huamin Liu, Xiaomin Gao, Lianguo Chen. A newly developed UPLC-MS/MS method for simultaneous quantitative analysis of ajuforrestin A, ajuforrestin B, ajugamacrin and 8-O-acetylharpagide derived from Ajuga plants in mice blood and the in vivo pharmacokinetics.
Drug development and industrial pharmacy.
2024 Apr; 50(4):354-362. doi:
10.1080/03639045.2024.2328731. [PMID: 38456836] - Shannon A Stirling, Angelica M Guercio, Ryan M Patrick, Xing-Qi Huang, Matthew E Bergman, Varun Dwivedi, Ruy W J Kortbeek, Yi-Kai Liu, Fuai Sun, W Andy Tao, Ying Li, Benoît Boachon, Nitzan Shabek, Natalia Dudareva. Volatile communication in plants relies on a KAI2-mediated signaling pathway.
Science (New York, N.Y.).
2024 Mar; 383(6689):1318-1325. doi:
10.1126/science.adl4685. [PMID: 38513014] - Ruonan Gao, Yilin Ren, Peng Xue, Yingyue Sheng, Qin Yang, Yuanyuan Dai, Xiaoyue Zhang, Ziming Lin, Tianhao Liu, Yan Geng, Yuzheng Xue. Protective Effect of the Polyphenol Ligustroside on Colitis Induced with Dextran Sulfate Sodium in Mice.
Nutrients.
2024 Feb; 16(4):. doi:
10.3390/nu16040522. [PMID: 38398846] - Kai Wang, Xiao-Lin Wen, Xu-Yang Chen, Ying Yue, Yu-Shun Yang, Hai-Liang Zhu, Miao-Yan Wang, Hao-Xiang Jiang. Promoting In Vivo NIR-II Fluorescent Imaging for Lipid in Lipid Metabolism Diseases Diagnosis.
Analytical chemistry.
2024 02; 96(5):2264-2272. doi:
10.1021/acs.analchem.3c05676. [PMID: 38266388] - Hong Che, Linlin Li, Bingjie Zhao, Lian Hu, Li Xiao, Peijia Liu, Songshan Liu, Zhufa Hou. Asperuloside alleviates cyclophosphamide-induced myelosuppression by promoting AMPK/mTOR pathway-mediated autophagy.
Journal of biochemical and molecular toxicology.
2024 Feb; 38(2):e23641. doi:
10.1002/jbt.23641. [PMID: 38348709] - Yuping Lu, Ian W Burton, Paula Ashe, Antony D St-Jacques, Nandhakishore Rajagopalan, Fanny Monteil-Rivera, Michele C Loewen. Characterization of a partially saturated and glycosylated apocarotenoid from wheat that is depleted upon leaf rust infection.
Gene.
2024 Jan; 893(?):147927. doi:
10.1016/j.gene.2023.147927. [PMID: 38374023] - Chao Yan, Zhihao Liu, Waner Xie, Ting Zhang, Jiyao Zhang, Guodong Li, Xiaoyan Xu, Lei Ye, Jianwei Gong. Cornuside protects against ischemic stroke in rats by suppressing the IL-17F/TRAF6/NF-κB pathway via the brain-gut axis.
Experimental neurology.
2023 Dec; 373(?):114672. doi:
10.1016/j.expneurol.2023.114672. [PMID: 38169196] - Shraddha I Khairnar, Yogesh A Kulkarni, S Murugesan, Kavita Singh. Effects of Acute and Repeated Dose Toxicity Profiling of Chelidonic Acid in Rats: in Silico and in Vivo Evidence.
Chemistry & biodiversity.
2023 Dec; 20(12):e202301241. doi:
10.1002/cbdv.202301241. [PMID: 37983725] - Muhammad Kamran, Kim T Melville, Mark T Waters. Karrikin signalling: impacts on plant development and abiotic stress tolerance.
Journal of experimental botany.
2023 Nov; ?(?):. doi:
10.1093/jxb/erad476. [PMID: 38001035] - Mark T Waters, David C Nelson. Karrikin perception and signalling.
The New phytologist.
2023 03; 237(5):1525-1541. doi:
10.1111/nph.18598. [PMID: 36333982] - Yuyue Qin, Linhu Zou, Xiaoguang Lei, Jiewei Su, Rixiu Yang, Wanjuan Xie, Wanshan Li, Guangying Chen. OSMAC strategy integrated with molecular networking discovery peniciacetals A-I, nine new meroterpenoids from the mangrove-derived fungus Penicillium sp. HLLG-122.
Bioorganic chemistry.
2023 01; 130(?):106271. doi:
10.1016/j.bioorg.2022.106271. [PMID: 36402026] - Run-Xin Liu, Yan-Ni Liang, Xuan-Xuan Ren, Qian-Qian Wu, Can Huang, Shi-Nian Cao, Yu Wan, Sheng-Liang Zhou, Rui Yuan, Hui Wu. Synthesis and Antibacterial Activity of Spiro[4H-pyran-3,3'-oxindoles] Catalyzed by Tröger's Base Derivative.
Current organic synthesis.
2023; 20(8):870-879. doi:
10.2174/1570179419666220614142611. [PMID: 35702794] - Marieke Dubois. KUFfed by drought: A KARRIKIN-upregulated F-box protein compromises plant growth and survival under drought.
Plant physiology.
2022 11; 190(4):2087-2089. doi:
10.1093/plphys/kiac413. [PMID: 36063030] - Xiujuan Lan, Ziyue Ying, Shengnan Guo, Yang Duan, Xinyu Cui, Aijing Leng, Xixiang Ying. Two novel amide alkaloids from Portulaca oleracea L. and their anti-inflammatory activities.
Natural product research.
2022 Nov; 36(21):5567-5574. doi:
10.1080/14786419.2021.2021519. [PMID: 34963386] - Okunola Adenrele Alabi, Halimat Chisom Atanda, John A V Olumurewa. Cytogenotoxicity of the aqueous extract of Parquetina nigrescens leaf using Allium cepa assay.
Protoplasma.
2022 Nov; 259(6):1417-1425. doi:
10.1007/s00709-022-01741-6. [PMID: 35146572] - Shuyan Han, Yongjin Wang, Zhongxiang Fang, Yiren Zhang, Wei Zeng, Emad Karrar, Hui Zhang, Qingzhe Jin, Gangcheng Wu, Xingguo Wang. Effect of olive polyphenols on lipid oxidation of high-fat beef during digestion.
Food research international (Ottawa, Ont.).
2022 11; 161(?):111843. doi:
10.1016/j.foodres.2022.111843. [PMID: 36192973] - Pingping Song, Bo Xu, Zhenying Liu, Yunxia Cheng, Zhimao Chao. The Difference of Volatile Compounds in Female and Male Buds of Trichosanthes anguina L. Based on HS-SPME-GC-MS and Multivariate Statistical Analysis.
Molecules (Basel, Switzerland).
2022 Oct; 27(20):. doi:
10.3390/molecules27207021. [PMID: 36296619] - Stephanie E Martinez, Caitlin E Conn, Angelica M Guercio, Claudia Sepulveda, Christopher J Fiscus, Daniel Koenig, Nitzan Shabek, David C Nelson. A KARRIKIN INSENSITIVE2 paralog in lettuce mediates highly sensitive germination responses to karrikinolide.
Plant physiology.
2022 Sep; 190(2):1440-1456. doi:
10.1093/plphys/kiac328. [PMID: 35809069] - He Liu, Mengnan An, Hongyang Si, Yuhang Shan, Chuantao Xu, Gang Hu, Yunbo Xie, Dongyang Liu, Shujun Li, Rui Qiu, Chong Zhang, Yuanhua Wu. Identification of Cyclic Dipeptides and a New Compound (6-(5-Hydroxy-6-methylheptyl)-5,6-dihydro-2H-pyran-2-one) Produced by Streptomyces fungicidicus against Alternaria solani.
Molecules (Basel, Switzerland).
2022 Sep; 27(17):. doi:
10.3390/molecules27175649. [PMID: 36080412] - Zhi-Peng Ling, Qing Tang, Can-Jie Li, Jin-Lin Tan, Hai-Yue Zhao, Yi-Kun Hao, Zhao-Chun Zhan, Zhong-Nan Wu, Yu-Bo Zhang, Qing Zheng, Guo-Cai Wang. Two new clerodane diterpenoids and a new pyran-2-one derivative with anti-neuroinflammatory activities from Croton crassifolius.
Journal of natural medicines.
2022 Sep; 76(4):849-856. doi:
10.1007/s11418-022-01630-5. [PMID: 35639239] - Jun-Zhuo Shi, Xiao-Ming Zheng, Yun-Feng Zhou, Lu-Yao Yun, Dong-Mei Luo, Jiao-Jiao Hao, Peng-Fei Liu, Wei-Ku Zhang, Jie-Kun Xu, Yi Yan, Xin-Mei Xie, Yang-Yang He, Xiao-Bin Pang. Cornuside Is a Potential Agent against Alzheimer's Disease via Orchestration of Reactive Astrocytes.
Nutrients.
2022 Aug; 14(15):. doi:
10.3390/nu14153179. [PMID: 35956355] - Yichen Tong, Wentao Zhu, Tianzhi Wen, Zere Mukhamejanova, Fang Xu, Qi Xiang, Jiyan Pang. Xyloketal B Reverses Nutritional Hepatic Steatosis, Steatohepatitis, and Liver Fibrosis through Activation of the PPARα/PGC1α Signaling Pathway.
Journal of natural products.
2022 07; 85(7):1738-1750. doi:
10.1021/acs.jnatprod.2c00259. [PMID: 35749236] - Ze-Xing Wang, Wen-Wen Lian, Jun He, Xiao-Li He, Yu-Ming Wang, Chen-Hao Pan, Mei Li, Wei-Ku Zhang, Lian-Qi Liu, Jie-Kun Xu. Cornuside ameliorates cognitive impairments in scopolamine induced AD mice: Involvement of neurotransmitter and oxidative stress.
Journal of ethnopharmacology.
2022 Jul; 293(?):115252. doi:
10.1016/j.jep.2022.115252. [PMID: 35405255] - Jae Young Kim, Young-Joon Park, June-Hee Lee, Chung-Mo Park. SMAX1 Integrates Karrikin and Light Signals into GA-Mediated Hypocotyl Growth during Seedling Establishment.
Plant & cell physiology.
2022 Jul; 63(7):932-943. doi:
10.1093/pcp/pcac055. [PMID: 35477800] - Maxime Hamon-Josse, José Antonio Villaécija-Aguilar, Karin Ljung, Ottoline Leyser, Caroline Gutjahr, Tom Bennett. KAI2 regulates seedling development by mediating light-induced remodelling of auxin transport.
The New phytologist.
2022 07; 235(1):126-140. doi:
10.1111/nph.18110. [PMID: 35313031] - Qiuying Zhang, Hui Liu, Dongmei Wu, Hongyan Yu, Kun Wang, Weijie Jiao, Xu Zhao. Methysticin Acts as a Mechanism-Based Inactivator of Cytochrome P450 2C9.
Chemical research in toxicology.
2022 06; 35(6):1117-1124. doi:
10.1021/acs.chemrestox.2c00098. [PMID: 35583123] - Haidy E Michel, Mariam M Tadros, Moataz S Hendy, Shereen Mowaka, Bassam M Ayoub. Omarigliptin attenuates rotenone-induced Parkinson's disease in rats: Possible role of oxidative stress, endoplasmic reticulum stress and immune modulation.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2022 Jun; 164(?):113015. doi:
10.1016/j.fct.2022.113015. [PMID: 35439590] - Yuri N Antonenko, Marta Jędrzejczyk, Tatyana I Rokitskaya, Ljudmila S Khailova, Elena A Kotova, Adam Huczyński. Rate of translocation across lipid bilayer of triphenylphosphonium-linked salinomycin derivatives contributes significantly to their K+/H+ exchange activity on membranes.
Bioelectrochemistry (Amsterdam, Netherlands).
2022 Jun; 145(?):108089. doi:
10.1016/j.bioelechem.2022.108089. [PMID: 35299152] - Qia Wang, Steven M Smith, Jinling Huang. Origins of strigolactone and karrikin signaling in plants.
Trends in plant science.
2022 05; 27(5):450-459. doi:
10.1016/j.tplants.2021.11.009. [PMID: 34876337] - Ochuko L Erukainure, Olubunmi Atolani, Aliyu Muhammad, Sanusi B Katsayal, Osadolor O Ebhuoma, Collins U Ibeji, M Ahmed Mesaik. Targeting the initiation and termination codons of SARS-CoV-2 spike protein as possible therapy against COVID-19: the role of novel harpagide 5-O-β-D-glucopyranoside from Clerodendrum volubile P Beauv. (Labiatae).
Journal of biomolecular structure & dynamics.
2022 04; 40(6):2475-2488. doi:
10.1080/07391102.2020.1840439. [PMID: 33140706] - Huihui Ti, Zixi Zhuang, Yan Li, Guozhu Wei, Fei Wang. Three new phenanthrenes from Pholidota chinensis Lindl. and their antibacterial activity.
Natural product research.
2022 Apr; 36(8):2056-2062. doi:
10.1080/14786419.2020.1845168. [PMID: 33185142] - Claudia Sepulveda, Michael A Guzmán, Qingtian Li, José Antonio Villaécija-Aguilar, Stephanie E Martinez, Muhammad Kamran, Aashima Khosla, Wei Liu, Joshua M Gendron, Caroline Gutjahr, Mark T Waters, David C Nelson. KARRIKIN UP-REGULATED F-BOX 1 (KUF1) imposes negative feedback regulation of karrikin and KAI2 ligand metabolism in Arabidopsis thaliana.
Proceedings of the National Academy of Sciences of the United States of America.
2022 03; 119(11):e2112820119. doi:
10.1073/pnas.2112820119. [PMID: 35254909] - Yongjie Meng, Kartikye Varshney, Norbert Incze, Eszter Badics, Muhammad Kamran, Sabrina F Davies, Larissa M F Oppermann, Kévin Magne, Marion Dalmais, Abdel Bendahmane, Richard Sibout, John Vogel, Debbie Laudencia-Chingcuanco, Charles S Bond, Vilmos Soós, Caroline Gutjahr, Mark T Waters. KARRIKIN INSENSITIVE2 regulates leaf development, root system architecture and arbuscular-mycorrhizal symbiosis in Brachypodium distachyon.
The Plant journal : for cell and molecular biology.
2022 03; 109(6):1559-1574. doi:
10.1111/tpj.15651. [PMID: 34953105] - Haifan Gong, Julia Bandura, Guan-Lei Wang, Zhong-Ping Feng, Hong-Shuo Sun. Xyloketal B: A marine compound with medicinal potential.
Pharmacology & therapeutics.
2022 02; 230(?):107963. doi:
10.1016/j.pharmthera.2021.107963. [PMID: 34375691] - Dongmei Hu, Shaojie Huang, Yi Ding, Xian Zhao, Wei Zhang, Haixia Chen, Jingwen Wang. Specnuezhenide reduces carbon tetrachloride-induced liver injury in mice through inhibition of oxidative stress and hepatocyte apoptosis.
The Journal of pharmacy and pharmacology.
2022 Feb; 74(2):191-199. doi:
10.1093/jpp/rgab164. [PMID: 34923584] - Xin-Ge Ke, Yi-Yi Xiong, Bing Yu, Chong Yuan, Peng-Yu Chen, Yan-Fang Yang, He-Zhen Wu. Mollugin induced oxidative DNA damage via up-regulating ROS that caused cell cycle arrest in hepatoma cells.
Chemico-biological interactions.
2022 Feb; 353(?):109805. doi:
10.1016/j.cbi.2022.109805. [PMID: 35007525] - Ryota Ochi, Kaori Yoneyama, Hisashi Nishiwaki, Satoshi Yamauchi. Structure-activity relationship of the aromatic moiety of 6-substituted 5,6-dihydro-2H-pyran-2-one to find the novel compound showing higher plant growth inhibitory activity.
Bioscience, biotechnology, and biochemistry.
2022 Jan; 86(2):165-169. doi:
10.1093/bbb/zbab185. [PMID: 34694328] - José Antonio Villaécija-Aguilar, Caroline Körösy, Lukas Maisch, Maxime Hamon-Josse, Andrea Petrich, Sonja Magosch, Philipp Chapman, Tom Bennett, Caroline Gutjahr. KAI2 promotes Arabidopsis root hair elongation at low external phosphate by controlling local accumulation of AUX1 and PIN2.
Current biology : CB.
2022 01; 32(1):228-236.e3. doi:
10.1016/j.cub.2021.10.044. [PMID: 34758285] - Yu-Luan Chen, Yao Shi, Amber LaFayette, Lei Shi, Kenneth S Koblan, Gerald R Galluppi. A sensitive LC-MS/MS method for simultaneous quantification of ulotaront and its N-desmethyl metabolite in human plasma and application to a clinical study.
Journal of pharmaceutical and biomedical analysis.
2022 Jan; 207(?):114404. doi:
10.1016/j.jpba.2021.114404. [PMID: 34700199] - Suzanne L Benedict, Orla M Mahony, Talon S McKee, Philip J Bergman. Evaluation of bexagliflozin in cats with poorly regulated diabetes mellitus.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire.
2022 Jan; 86(1):52-58. doi:
NULL. [PMID: 34975223] - Cho R Hong, Chantal D Buckley, Way W Wong, Praju V Anekal, Benjamin D Dickson, Gib Bogle, Kevin O Hicks, Michael P Hay, William R Wilson. Radiosensitisation of SCCVII tumours and normal tissues in mice by the DNA-dependent protein kinase inhibitor AZD7648.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.
2022 01; 166(?):162-170. doi:
10.1016/j.radonc.2021.11.027. [PMID: 34861268] - Adila Tuerxuntayi, Abudourusuli Tusun, Abulikemu Tajiguli. Rapid detection and structural characterization of methysticin metabolites generated from rat and human liver microsomes and hepatocytes using ultra-high-performance liquid chromatography coupled with high-resolution mass spectrometry.
Rapid communications in mass spectrometry : RCM.
2021 Dec; 35(24):e9208. doi:
10.1002/rcm.9208. [PMID: 34606659] - Ling Li, Kelei Qian, Yuli Sun, Yong Zhao, Yun Zhou, Ying Xue, Xinyu Hong. Omarigliptin ameliorated high glucose-induced nucleotide oligomerization domain-like receptor protein 3 (NLRP3) inflammasome activation through activating adenosine monophosphate-activated protein kinase α (AMPKα) in renal glomerular endothelial cells.
Bioengineered.
2021 12; 12(1):4805-4815. doi:
10.1080/21655979.2021.1957748. [PMID: 34338149] - Zeyu Li, Hong Wang, Kanglin Wu, Lianfeng Zhang. Omarigliptin protects against nonalcoholic fatty liver disease by ameliorating oxidative stress and inflammation.
Journal of biochemical and molecular toxicology.
2021 Dec; 35(12):e22914. doi:
10.1002/jbt.22914. [PMID: 34533252] - Takashi Akazawa, Hikaru Itami, Toshio Furumoto, Chie Nozaki, Hiroyuki Koike, Saika Iritani, Naoyuki Amimoto, Masahiro Ogawa. Impact of an Olive Leaf Polyphenol 3,4-DHPEA-EDA on Physical Properties of Food Protein Gels.
Journal of agricultural and food chemistry.
2021 Dec; 69(47):14250-14258. doi:
10.1021/acs.jafc.1c04661. [PMID: 34730369] - Heng Zhang, Junfeng Lu, Hao Liu, Lingling Guan, Shiqing Xu, Zai Wang, Yang Qiu, Honglin Liu, Liang Peng, Xiuli Men. Ajugol enhances TFEB-mediated lysosome biogenesis and lipophagy to alleviate non-alcoholic fatty liver disease.
Pharmacological research.
2021 12; 174(?):105964. doi:
10.1016/j.phrs.2021.105964. [PMID: 34732369] - Omar Azzam, Revathy Carnagarin, Leslie Marisol Lugo-Gavidia, Janis Nolde, Vance B Matthews, Markus P Schlaich. Bexagliflozin for type 2 diabetes: an overview of the data.
Expert opinion on pharmacotherapy.
2021 Nov; 22(16):2095-2103. doi:
10.1080/14656566.2021.1959915. [PMID: 34292100] - Yurong Wang, Yan Wang, Kai Xue, Feng Gao, Chengde Li, Hui Fang. Elevated reactivity of Apelin inhibited renal fibrosis induced by chronic intermittent hypoxia.
Archives of biochemistry and biophysics.
2021 10; 711(?):109021. doi:
10.1016/j.abb.2021.109021. [PMID: 34464591] - Fatemeh Kalantari, Ali Ramazani, Mohammad Reza Poor Heravi, Hamideh Aghahosseini, Katarzyna Ślepokura. Magnetic Nanoparticles Functionalized with Copper Hydroxyproline Complexes as an Efficient, Recoverable, and Recyclable Nanocatalyst: Synthesis and Its Catalytic Application in a Tandem Knoevenagel-Michael Cyclocondensation Reaction.
Inorganic chemistry.
2021 Oct; 60(19):15010-15023. doi:
10.1021/acs.inorgchem.1c02470. [PMID: 34533947] - Gerald R Galluppi, Daniel G Polhamus, Jeannine M Fisher, Seth C Hopkins, Kenneth S Koblan. Population pharmacokinetic analysis of ulotaront in subjects with schizophrenia.
CPT: pharmacometrics & systems pharmacology.
2021 10; 10(10):1245-1254. doi:
10.1002/psp4.12692. [PMID: 34292664] - Faheem Afzal Shah, Jun Ni, Caiguo Tang, Xue Chen, Wenjie Kan, Lifang Wu. Karrikinolide alleviates salt stress in wheat by regulating the redox and K+/Na+ homeostasis.
Plant physiology and biochemistry : PPB.
2021 Oct; 167(?):921-933. doi:
10.1016/j.plaphy.2021.09.023. [PMID: 34555666] - Hilmican Caliskan, Merve Ozer, Temine Sabudak, H Hulya Orak. A new pyran derivative analog from the whole plant of Cirsium italicum.
Journal of Asian natural products research.
2021 Oct; 23(10):1009-1014. doi:
10.1080/10286020.2020.1816977. [PMID: 32924587] - Yunwei Lu, Renjuan Hao, Yingchao Hu, Yuyan Wei, Yuyan Xie, Yu Shen, Qinglin Rui, Guran Yu. Harpagide alleviate neuronal apoptosis and blood-brain barrier leakage by inhibiting TLR4/MyD88/NF-κB signaling pathway in Angiotensin II-induced microglial activation in vitro.
Chemico-biological interactions.
2021 Oct; 348(?):109653. doi:
10.1016/j.cbi.2021.109653. [PMID: 34516974] - Sanchita Gupta, Tripti Mishra, Salil Varshney, Vinita Kushawaha, Nilesh Khandelwal, Prashant Rai, Richa Garg, Kapil Dev, Abhishek Gupta, Durgesh Kumar, Vishal M Balaramnavar, Kamal Ram Arya, Jiaur R Gayen, Tadigoppula Narender, Anil Nilkanth Gaikwad. Coelogin ameliorates metabolic dyshomeostasis by regulating adipogenesis and enhancing energy expenditure in adipose tissue.
Pharmacological research.
2021 10; 172(?):105776. doi:
10.1016/j.phrs.2021.105776. [PMID: 34450319] - Katharina Bursch, Ella T Niemann, David C Nelson, Henrik Johansson. Karrikins control seedling photomorphogenesis and anthocyanin biosynthesis through a HY5-BBX transcriptional module.
The Plant journal : for cell and molecular biology.
2021 09; 107(5):1346-1362. doi:
10.1111/tpj.15383. [PMID: 34160854] - Makoto Ohara, Hiroe Nagaike, Tomoki Fujikawa, Yo Kohata, Maiho Ogawa, Takemasa Omachi, Risa Sasajima, Hirotoshi Chiba, Toshimasa Ara, Ayuka Sugawara, Munenori Hiromura, Michishige Terasaki, Yusaku Mori, Tomoyasu Fukui, Tsutomu Hirano, Hiroki Yokoyama, Sho-Ichi Yamagishi. Effects of omarigliptin on glucose variability and oxidative stress in type 2 diabetes patients: A prospective study.
Diabetes research and clinical practice.
2021 Sep; 179(?):108999. doi:
10.1016/j.diabres.2021.108999. [PMID: 34390762] - Suparna Mercy Basu, Sunil Kumar Yadava, Ruby Singh, Jyotsnendu Giri. Lipid nanocapsules co-encapsulating paclitaxel and salinomycin for eradicating breast cancer and cancer stem cells.
Colloids and surfaces. B, Biointerfaces.
2021 Aug; 204(?):111775. doi:
10.1016/j.colsurfb.2021.111775. [PMID: 33940518] - Yong-Er Chen, Shi-Jie Xu, Ying-Yu Lu, Shu-Xian Chen, Xian-Hua Du, Shao-Zhen Hou, Hai-Yang Huang, Jian Liang. Asperuloside suppressing oxidative stress and inflammation in DSS-induced chronic colitis and RAW 264.7 macrophages via Nrf2/HO-1 and NF-κB pathways.
Chemico-biological interactions.
2021 Aug; 344(?):109512. doi:
10.1016/j.cbi.2021.109512. [PMID: 33974900] - Amir Arellano-Saab, Michael Bunsick, Hasan Al Galib, Wenda Zhao, Stefan Schuetz, James Michael Bradley, Zhenhua Xu, Claresta Adityani, Asrinus Subha, Hayley McKay, Alexandre de Saint Germain, François-Didier Boyer, Christopher S P McErlean, Shigeo Toh, Peter McCourt, Peter J Stogios, Shelley Lumba. Three mutations repurpose a plant karrikin receptor to a strigolactone receptor.
Proceedings of the National Academy of Sciences of the United States of America.
2021 07; 118(30):. doi:
10.1073/pnas.2103175118. [PMID: 34301902] - Ravi Prakash, Tripti Mishra, Kapil Dev, Kriti Sharma, Jitendra Kuldeep, Aijaz Ahmad John, Alok Tripathi, Chetan Sharma, Kamal Ram Arya, Brijesh Kumar, Mohd Imran Siddiqi, Narender Tadigoppula, Divya Singh. Phenanthrenoid Coelogin Isolated from Coelogyne cristata Exerts Osteoprotective Effect Through MAPK-Mitogen-Activated Protein Kinase Signaling Pathway.
Calcified tissue international.
2021 07; 109(1):32-43. doi:
10.1007/s00223-021-00818-3. [PMID: 33675370] - Lixian Chen, Tianhao Zhou, Tori White, April O'Brien, Sanjukta Chakraborty, Suthat Liangpunsakul, Zhihong Yang, Lindsey Kennedy, Romil Saxena, Chaodong Wu, Fanyin Meng, Qiaobing Huang, Heather Francis, Gianfranco Alpini, Shannon Glaser. The Apelin-Apelin Receptor Axis Triggers Cholangiocyte Proliferation and Liver Fibrosis During Mouse Models of Cholestasis.
Hepatology (Baltimore, Md.).
2021 06; 73(6):2411-2428. doi:
10.1002/hep.31545. [PMID: 32964473] - Han Luo, Yong-Feng Lv, Hong Zhang, Jiang-Miao Hu, Hong-Mei Li, Shou-Jin Liu. Synthesis and Antitumor Activity of 1-Substituted 1,2,3-Triazole-Mollugin Derivatives.
Molecules (Basel, Switzerland).
2021 May; 26(11):. doi:
10.3390/molecules26113249. [PMID: 34071319] - Rongbo Zhang, Jin Liu, Bin Xu, You Wu, Shunli Liang, Qiang Yuan. Cornuside alleviates experimental autoimmune encephalomyelitis by inhibiting Th17 cell infiltration into the central nervous system.
Journal of Zhejiang University. Science. B.
2021 May; 22(5):421-430. doi:
10.1631/jzus.b2000771. [PMID: 33973423] - Farhad Rostami, Kamran Taherpour, Hossein Ali Ghasemi, Mohammad Akbari Gharaei, Hassan Shirzadi. Effects of Scrophularia striata hydroalcoholic extract in comparison to salinomycin on growth performance, intestinal health and immunity in broiler chickens following a mixed-species Eimeria challenge.
Veterinary parasitology.
2021 May; 293(?):109417. doi:
10.1016/j.vetpar.2021.109417. [PMID: 33819905] - Soumava Santra, Sandhya Kortagere, Seenuvasan Vedachalam, Sanjib Gogoi, Tamara Antonio, Maarten E A Reith, Aloke K Dutta. Novel Potent Dopamine-Norepinephrine and Triple Reuptake Uptake Inhibitors Based on Asymmetric Pyran Template and Their Molecular Interactions with Monoamine Transporters.
ACS chemical neuroscience.
2021 04; 12(8):1406-1418. doi:
10.1021/acschemneuro.1c00078. [PMID: 33844493] - Seth C Hopkins, Nina Dedic, Kenneth S Koblan. Effect of TAAR1/5-HT1A agonist SEP-363856 on REM sleep in humans.
Translational psychiatry.
2021 04; 11(1):228. doi:
10.1038/s41398-021-01331-9. [PMID: 33879769] - Aqeel Ahmad, Iqra Shahzadi, Samavia Mubeen, Nasim Ahmad Yasin, Waheed Akram, Waheed Ullah Khan, Tingquan Wu. Karrikinolide alleviates BDE-28, heat and Cd stressors in Brassica alboglabra by correlating and modulating biochemical attributes, antioxidative machinery and osmoregulators.
Ecotoxicology and environmental safety.
2021 Apr; 213(?):112047. doi:
10.1016/j.ecoenv.2021.112047. [PMID: 33601172] - Hui Sun, Weina Ding, Wanying Duan, Jie Zhou, Lanping Guo. Proteomic reveals the influences of smoke-water and karrikinolide on the biosynthesis of salvianolic acids and lignins in Salvia miltiorrhiza hairy roots.
Planta.
2021 Apr; 253(5):87. doi:
10.1007/s00425-021-03619-y. [PMID: 33811528] - Hussein M El-Zaher, Sherif Y Eid, Mahmoud M Shaaban, Omar A Ahmed-Farid, Ahmed M Abd El Tawab, Mostafa S A Khattab. Ovarian activity and antioxidant indices during estrous cycle of Barki ewes under effect of thyme, celery and salinomycin as feed additives.
Zygote (Cambridge, England).
2021 Apr; 29(2):155-160. doi:
10.1017/s0967199420000611. [PMID: 33228827] - Dóra Oláh, Árpád Molnár, Vilmos Soós, Zsuzsanna Kolbert. Nitric oxide is associated with strigolactone and karrikin signal transduction in Arabidopsis roots.
Plant signaling & behavior.
2021 03; 16(3):1868148. doi:
10.1080/15592324.2020.1868148. [PMID: 33446007] - Raquel Bridi, Gilsane Lino von Poser, Miguel Gómez, Marcelo E Andia, Juan Esteban Oyarzún, Paula Núñez, Ariadsna Jael Vasquez Arias, Christian Espinosa-Bustos. Hepatoprotective species from the Chilean medicinal flora: Junellia spathulata (Verbenaceae).
Journal of ethnopharmacology.
2021 Mar; 267(?):113543. doi:
10.1016/j.jep.2020.113543. [PMID: 33152429] - Bassam M Ayoub, Haidy E Michel, Shereen Mowaka, Moataz S Hendy, Mariam M Tadros. Repurposing of Omarigliptin as a Neuroprotective Agent Based on Docking with A2A Adenosine and AChE Receptors, Brain GLP-1 Response and Its Brain/Plasma Concentration Ratio after 28 Days Multiple Doses in Rats Using LC-MS/MS.
Molecules (Basel, Switzerland).
2021 Feb; 26(4):. doi:
10.3390/molecules26040889. [PMID: 33567615] - Liping Zeng, Tianyi Xu, Jie Meng, Dingfang Wu, Shihua Wu. H2O-Induced Hydrophobic Interactions in MS-Guided Counter-Current Chromatography Separation of Anti-Cancer Mollugin from Rubia cordifolia.
Molecules (Basel, Switzerland).
2021 Feb; 26(3):. doi:
10.3390/molecules26030751. [PMID: 33540504] - Tin Myo Thant, Nanik Siti Aminah, Alfinda Novi Kristanti, Rico Ramadhan, Preecha Phuwapraisirisan, Yoshiaki Takaya. A new pyrano coumarin from Clausena excavata roots displaying dual inhibition against α-glucosidase and free radical.
Natural product research.
2021 Feb; 35(4):556-561. doi:
10.1080/14786419.2019.1586696. [PMID: 30908081] - Huan Shen, Changquan Calvin Sun, Lichun Kang, Xiaoyue Tan, Peng Shi, Lingyu Wang, Ergang Liu, Junbo Gong. Low-dose salinomycin inhibits breast cancer metastasis by repolarizing tumor hijacked macrophages toward the M1 phenotype.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2021 Feb; 157(?):105629. doi:
10.1016/j.ejps.2020.105629. [PMID: 33176191] - Hui Sun, Qian Liu, Jie Zhou, Lanping Guo. Metabolomics reveals the influences of smoke-water and karrikinolide on the biosynthesis of flavonoids and terpenoids in Salvia miltiorrhiza.
Functional plant biology : FPB.
2021 02; 48(3):321-332. doi:
10.1071/fp20172. [PMID: 33242388] - Muhammad Ishaq, Duyen Tran, Yijia Wu, Krzysztof Nowak, Bianca J Deans, Joycelin Tan Zhu Xin, Hui Lin Loh, Wen Ying Ng, Chin Wen Yee, Benjamin Southam, Silvia Vicenzi, Cameron Randall, Cheng Yang, Ee Tan, Manideepika Pasupuleti, Avneet Kaur Grewal, Tauseef Ahmad, Madhur Shastri, Carmelo Vicario, Maurizio Ronci, Mariachiara Zuccarini, Martin Bleasel, Paul Scowen, William Raffaeli, Gianvicenzo D'Andrea, Dinesh Kumar Chellappan, Glenn Jacobson, Alex C Bissember, Jason A Smith, Raj Eri, Juan Canales, Miguel Iglesias, Nuri Guven, Vanni Caruso. Asperuloside Enhances Taste Perception and Prevents Weight Gain in High-Fat Fed Mice.
Frontiers in endocrinology.
2021; 12(?):615446. doi:
10.3389/fendo.2021.615446. [PMID: 33927690] - Robert Gintrowicz, Klemens Pawloy, Antje Degel. Social distancing in advanced emergency medicine courses - can it work?.
GMS journal for medical education.
2021 ; 38(1):Doc22. doi:
10.3205/zma001418. [PMID: 33659627] - Qin-Qin Wang, Shan Han, Xin-Xing Li, Renyikun Yuan, Youqiong Zhuo, Xinxin Chen, Chenwei Zhang, Yangling Chen, Hongwei Gao, Li-Chun Zhao, Shilin Yang. Nuezhenide Exerts Anti-Inflammatory Activity through the NF-κB Pathway.
Current molecular pharmacology.
2021; 14(1):101-111. doi:
10.2174/1874467213666200611141337. [PMID: 32525787] - Aurora Salamanca, Paula Almodóvar, Irene Jarama, Daniel González-Hedström, Marin Prodanov, Antonio Manuel Inarejos-García. Anti-influenza virus activity of the elenolic acid rich olive leaf (Olea europaea L.) extract Isenolic®.
Antiviral chemistry & chemotherapy.
2021 Jan; 29(?):20402066211063391. doi:
10.1177/20402066211063391. [PMID: 34839747] - Dan Gao, Vinh Le Ba, Rustamov Rustam, Chong Woon Cho, Seo Young Yang, Xiang Dong Su, Young Ho Kim, Jong Seong Kang. Isolation of bioactive components with soluble epoxide hydrolase inhibitory activity from Stachys sieboldii MiQ. by ultrasonic-assisted extraction optimized using response surface methodology.
Preparative biochemistry & biotechnology.
2021; 51(4):395-404. doi:
10.1080/10826068.2020.1821217. [PMID: 32940554] - Lei Dou, Xinxin Zhang, Mohammad Mahdi Zangeneh, Yi Zhang. Efficient biogenesis of Cu2O nanoparticles using extract of Camellia sinensis leaf: Evaluation of catalytic, cytotoxicity, antioxidant, and anti-human ovarian cancer properties.
Bioorganic chemistry.
2021 01; 106(?):104468. doi:
10.1016/j.bioorg.2020.104468. [PMID: 33229117] - Samy Carbonnel, Salar Torabi, Maximilian Griesmann, Elias Bleek, Yuhong Tang, Stefan Buchka, Veronica Basso, Mitsuru Shindo, François-Didier Boyer, Trevor L Wang, Michael Udvardi, Mark T Waters, Caroline Gutjahr. Lotus japonicus karrikin receptors display divergent ligand-binding specificities and organ-dependent redundancy.
PLoS genetics.
2020 12; 16(12):e1009249. doi:
10.1371/journal.pgen.1009249. [PMID: 33370251] - Anis Ali Shah, Waheed Ullah Khan, Nasim Ahmad Yasin, Waheed Akram, Aqeel Ahmad, Muhammad Abbas, Aamir Ali, Muhammad Naeem Safdar. Butanolide alleviated cadmium stress by improving plant growth, photosynthetic parameters and antioxidant defense system of brassica oleracea.
Chemosphere.
2020 Dec; 261(?):127728. doi:
10.1016/j.chemosphere.2020.127728. [PMID: 32731022] - Wei-Hsiang Hsu, Bing-Ze Lin, Jyh-Der Leu, Pin-Ho Lo, Hsueh-Yen Yu, Chao-Tsung Chen, Yuan-Heng Tu, Yun-Lian Lin, Yi-Jang Lee. Involvement of 8-O-acetylharpagide for Ajuga taiwanensis mediated suppression of senescent phenotypes in human dermal fibroblasts.
Scientific reports.
2020 11; 10(1):19731. doi:
10.1038/s41598-020-76797-6. [PMID: 33184359] - Ji-Long Zhang, Xiaoting Liu, Hong-Xing Zhang. Interaction Mechanism of the Germination Stimulants Karrikins and Their Receptor ShKAI2iB.
The journal of physical chemistry. B.
2020 11; 124(44):9812-9819. doi:
10.1021/acs.jpcb.0c06734. [PMID: 33089685] - Claudio Frezza, Daniela de Vita, Chiara Toniolo, Antonio Ventrone, Lamberto Tomassini, Sebastiano Foddai, Marcello Nicoletti, Marcella Guiso, Armandodoriano Bianco, Mauro Serafini. Harpagide: Occurrence in plants and biological activities - A review.
Fitoterapia.
2020 Nov; 147(?):104764. doi:
10.1016/j.fitote.2020.104764. [PMID: 33122133] - Reza Abbasi, Bahman Abdi-Hachesoo, Seyed Mostafa Razavi, Fatemeh Namazi, Saeed Nazifi. In vitro and in vivo activity of cinnamaldehyde against Eimeria kofoidi in chukar partridge (Alectoris chukar).
Experimental parasitology.
2020 Nov; 218(?):107978. doi:
10.1016/j.exppara.2020.107978. [PMID: 32853633] - Ibtissem Ben Hammouda, Gloria Márquez-Ruiz, Francisca Holgado, Ammar Sonda, Krystyna Skalicka-Wozniak, Mohamed Bouaziz. RP-UHPLC-DAD-QTOF-MS As a Powerful Tool of Oleuropein and Ligstroside Characterization in Olive-Leaf Extract and Their Contribution to the Improved Performance of Refined Olive-Pomace Oil during Heating.
Journal of agricultural and food chemistry.
2020 Oct; 68(43):12039-12047. doi:
10.1021/acs.jafc.0c05509. [PMID: 33054204] - Amana Khatoon, Shafiq Ur Rehman, Muhammad Mudasar Aslam, Muhammad Jamil, Setsuko Komatsu. Plant-Derived Smoke Affects Biochemical Mechanism on Plant Growth and Seed Germination.
International journal of molecular sciences.
2020 Oct; 21(20):. doi:
10.3390/ijms21207760. [PMID: 33092218] - Nikolaos Tsakiris, Frédérique Fauvet, Samia Ruby, Alain Puisieux, Adrien Paquot, Giulio G Muccioli, Arnaud M Vigneron, Véronique Préat. Combined nanomedicines targeting colorectal cancer stem cells and cancer cells.
Journal of controlled release : official journal of the Controlled Release Society.
2020 10; 326(?):387-395. doi:
10.1016/j.jconrel.2020.07.025. [PMID: 32702392] - Sai Kiran S S Pindiprolu, Chirravuri S Phani Kumar, Venu Sampath Kumar Golla, Likitha P, Shreyas Chandra K, Esub Basha S K, Ramachandra R K. Pulmonary delivery of nanostructured lipid carriers for effective repurposing of salinomycin as an antiviral agent.
Medical hypotheses.
2020 Oct; 143(?):109858. doi:
10.1016/j.mehy.2020.109858. [PMID: 32516655] - K V Sivak, K I Stosman, T A Rassokha, A G Aleksandrov, N N Kuzmich, Ya R Orshanskaya, T N Savateeva-Lubimova, E E Lesiovskaya. The Effect of TLR4 Blockade on Some Indicators of Systemic Inflammatory Response to Proteus mirabilis LPS in Rats.
Bulletin of experimental biology and medicine.
2020 Oct; 169(6):795-797. doi:
10.1007/s10517-020-04981-9. [PMID: 33098506] - Zhen Xiao, Cilong Chu, Lingjia Zhou, Zhihui Zhou, Qian Zhang, Feiyi Yang, Zunhua Yang, Pengwu Zheng, Shan Xu, Wufu Zhu. Discovery of thiapyran-pyrimidine derivatives as potential EGFR inhibitors.
Bioorganic & medicinal chemistry.
2020 10; 28(19):115669. doi:
10.1016/j.bmc.2020.115669. [PMID: 32912435] - Juan Li, Jin-Ling Zhang, Xue-Peng Gong, Meng Xiao, Yuan-Yuan Song, Hui-Fang Pi, Guang Du. Anti-inflammatory Activity of Mollugin on DSS-induced Colitis in Mice.
Current medical science.
2020 Oct; 40(5):910-916. doi:
10.1007/s11596-020-2262-5. [PMID: 33123905]
