Spirobrassinin (BioDeep_00000840835)
代谢物信息卡片
化学式: C11H10N2OS2 (250.0235)
中文名称:
谱图信息:
最多检出来源 () %
分子结构信息
SMILES: CSC1=NCC2(S1)C(=O)NC1=C2C=CC=C1
InChI: InChI=1S/C11H10N2OS2/c1-15-10-12-6-11(16-10)7-4-2-3-5-8(7)13-9(11)14/h2-5H,6H2,1H3,(H,13,14)
描述信息
(s)-spirobrassinin is a member of the class of compounds known as indolines. Indolines are compounds containing an indole moiety, which consists of pyrrolidine ring fused to benzene to form 2,3-dihydroindole (s)-spirobrassinin is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). (s)-spirobrassinin can be found in brassicas, which makes (s)-spirobrassinin a potential biomarker for the consumption of this food product.
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome()
BioCyc()
PlantCyc()
代谢反应
个相关的代谢反应过程信息。
Reactome()
BioCyc()
WikiPathways()
Plant Reactome()
INOH()
PlantCyc()
COVID-19 Disease Map()
PathBank()
PharmGKB()
个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Kaori Ryu, Seikou Nakamura, Souichi Nakashima, Hisashi Matsuda. One-pot enantioselective synthesis of (S)-spirobrassinin and non-natural (S)-methylspirobrassinin from amino acids using a turnip enzyme.
Journal of natural medicines.
2021 Mar; 75(2):308-318. doi:
10.1007/s11418-020-01468-9. [PMID: 33389552] - Tae Hyun Lee, Zahra Khan, Sun Yeou Kim, Kang Ro Lee. Thiohydantoin and Hydantoin Derivatives from the Roots of Armoracia rusticana and Their Neurotrophic and Anti-neuroinflammatory Activities.
Journal of natural products.
2019 11; 82(11):3020-3024. doi:
10.1021/acs.jnatprod.9b00527. [PMID: 31625742] - Andrew P Klein, Elizabeth S Sattely. Two cytochromes P450 catalyze S-heterocyclizations in cabbage phytoalexin biosynthesis.
Nature chemical biology.
2015 Nov; 11(11):837-9. doi:
10.1038/nchembio.1914. [PMID: 26389737] - M Soledade C Pedras, Paulos B Chumala, Wei Jin, Mohammed S Islam, Dominic W Hauck. The phytopathogenic fungus Alternaria brassicicola: phytotoxin production and phytoalexin elicitation.
Phytochemistry.
2009 Feb; 70(3):394-402. doi:
10.1016/j.phytochem.2009.01.005. [PMID: 19223049] - M Soledade C Pedras, Denis P O Okinyo. Remarkable incorporation of the first sulfur containing indole derivative: another piece in the biosynthetic puzzle of crucifer phytoalexins.
Organic & biomolecular chemistry.
2008 Jan; 6(1):51-4. doi:
10.1039/b714743k. [PMID: 18075646] - M S C Pedras, M Hossain, M G Sarwar, S Montaut. Determination of the enantiomeric purity of the phytoalexins spirobrassinins by 1H NMR using chiral solvation.
Bioorganic & medicinal chemistry letters.
2004 Nov; 14(22):5469-71. doi:
10.1016/j.bmcl.2004.09.014. [PMID: 15482905] - R Mezencev, J Mojzis, M Pilatova, P Kutschy. Antiproliferative and cancer chemopreventive activity of phytoalexins: focus on indole phytoalexins from crucifers.
Neoplasma.
2003; 50(4):239-45. doi:
. [PMID: 12937834] - K Monde, N Harada, M Takasugi, P Kutschy, M Suchy, M Dzurilla. Enantiomeric excess of a cruciferous phytoalexin, spirobrassinin, and its enantiomeric enrichment in an achiral HPLC system.
Journal of natural products.
2000 Sep; 63(9):1312-4. doi:
10.1021/np000043t. [PMID: 11000049] - N Loreau, C Lepreux, R Ardaillou. Calcitonin-sensitive adenylate cyclase in rat renal tubular membranes.
The Biochemical journal.
1975 Sep; 150(3):305-14. doi:
10.1042/bj1500305. [PMID: 2153]
