Methanesulfinate (BioDeep_00000840598)
代谢物信息卡片
Methanesulfinate
化学式: CH3O2S- (78.9854)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CS(=O)[O-]
InChI: InChI=1S/CH4O2S/c1-4(2)3/h1H3,(H,2,3)/p-1
相关代谢途径
Reactome(0)
PlantCyc(0)
代谢反应
1 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(1)
- dimethyl sulfide degradation II (oxidation):
H+ + NADPH + O2 + dimethyl sulfide ⟶ H2O + NADP+ + dimethyl sulfoxide
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Shakil A Saghir, Barry L Yano, Carol L Zablotny, Kathy A Brzak, Amy J Clark, Jennifer L Staley. Role of iodine in the toxicity of diiodomethyl-p-tolylsulfone (DIMPTS) in rats: ADME.
Regulatory toxicology and pharmacology : RTP.
2012 Apr; 62(3):482-95. doi:
10.1016/j.yrtph.2011.09.006. [PMID: 21986257] - Oludotun Adebayo Phillips, Edet Ekpenyong Udo, Reny Varghese. Antimycobacterial Activities of Novel 5-(1H-1,2,3-Triazolyl)Methyl Oxazolidinones.
Tuberculosis research and treatment.
2012; 2012(?):289136. doi:
10.1155/2012/289136. [PMID: 22577542] - Matthew Hoffmann, Gondi Kumar, Peter Schafer, Dorota Cedzik, Lori Capone, Kei-Lai Fong, Zheming Gu, Dennis Heller, Hao Feng, Sekhar Surapaneni, Oscar Laskin, Anfan Wu. Disposition, metabolism and mass balance of [(14)C]apremilast following oral administration.
Xenobiotica; the fate of foreign compounds in biological systems.
2011 Dec; 41(12):1063-75. doi:
10.3109/00498254.2011.604745. [PMID: 21859393] - Kelem Kassahun, W Cameron Black, Deborah Nicoll-Griffith, Ian McIntosh, Nathalie Chauret, Stephen Day, Elizabeth Rosenberg, Kenneth Koeplinger. Pharmacokinetics and metabolism in rats, dogs, and monkeys of the cathepsin k inhibitor odanacatib: demethylation of a methylsulfonyl moiety as a major metabolic pathway.
Drug metabolism and disposition: the biological fate of chemicals.
2011 Jun; 39(6):1079-87. doi:
10.1124/dmd.110.037184. [PMID: 21422190] - Khaled M Elokely, Mohamed A Eldawy, Mohamed A Elkersh, Tarek F El-Moselhy. Fluorescence Spectrometric Determination of Drugs Containing α-Methylene Sulfone/Sulfonamide Functional Groups Using N-Methylnicotinamide Chloride as a Fluorogenic Agent.
International journal of analytical chemistry.
2011; 2011(?):840178. doi:
10.1155/2011/840178. [PMID: 21647288] - David G Levitt. Quantitative relationship between the octanol/water partition coefficient and the diffusion limitation of the exchange between adipose and blood.
BMC clinical pharmacology.
2010 Jan; 10(?):1. doi:
10.1186/1472-6904-10-1. [PMID: 20055995] - Jiyan Liu, Dingfei Hu, Guibin Jiang, Jerald L Schnoor. In vivo biotransformation of 3,3',4,4'-tetrachlorobiphenyl by whole plants-poplars and switchgrass.
Environmental science & technology.
2009 Oct; 43(19):7503-9. doi:
10.1021/es901244h. [PMID: 19848168] - Renée Dallaire, Eric Dewailly, Daria Pereg, Serge Dery, Pierre Ayotte. Thyroid function and plasma concentrations of polyhalogenated compounds in Inuit adults.
Environmental health perspectives.
2009 Sep; 117(9):1380-6. doi:
10.1289/ehp.0900633. [PMID: 19750101] - David M Pettigrew, Pietro Roversi, Stephen G Davies, Angela J Russell, Susan M Lea. A structural study of the interaction between the Dr haemagglutinin DraE and derivatives of chloramphenicol.
Acta crystallographica. Section D, Biological crystallography.
2009 Jun; 65(Pt 6):513-22. doi:
10.1107/s0907444909005113. [PMID: 19465765] - Heli Routti, Robert J Letcher, Augustine Arukwe, Bert Van Bavel, Nigel G Yoccoz, Shaogang Chu, Geir W Gabrielsen. Biotransformation of PCBs in relation to phase I and II xenobiotic-metabolizing enzyme activities in ringed seals (Phoca hispida) from Svalbard and the Baltic Sea.
Environmental science & technology.
2008 Dec; 42(23):8952-8. doi:
10.1021/es801682f. [PMID: 19192824] - Khaled R A Abdellatif, Morshed Alam Chowdhury, Ying Dong, Carlos Velázquez, Dipankar Das, Mavanur R Suresh, Edward E Knaus. Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-hydroxymethylphenyl)-1-(4-aminosulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its methanesulfonyl analog: synthesis, biological evaluation and nitric oxide release studies.
Bioorganic & medicinal chemistry.
2008 Nov; 16(22):9694-8. doi:
10.1016/j.bmc.2008.10.001. [PMID: 18930406] - Linda Linderholm, June-Soo Park, Anton Kocan, Tomas Trnovec, Maria Athanasiadou, Ke Bergman, Irva Hertz-Picciotto. Maternal and cord serum exposure to PCB and DDE methyl sulfone metabolites in eastern Slovakia.
Chemosphere.
2007 Sep; 69(3):403-10. doi:
10.1016/j.chemosphere.2007.04.081. [PMID: 17574648] - Jonathan Verreault, Robert J Letcher, Erik Ropstad, Ellen Dahl, Geir W Gabrielsen. Organohalogen contaminants and reproductive hormones in incubating glaucous gulls (Larus hyperboreus) from the Norwegian Arctic.
Environmental toxicology and chemistry.
2006 Nov; 25(11):2990-6. doi:
10.1897/05-634r.1. [PMID: 17089723] - Melissa A McKinney, Sylvain De Guise, Daniel Martineau, Pierre Béland, Michel Lebeuf, Robert J Letcher. Organohalogen contaminants and metabolites in beluga whale (Delphinapterus leucas) liver from two Canadian populations.
Environmental toxicology and chemistry.
2006 May; 25(5):1246-57. doi:
10.1897/05-284r.1. [PMID: 16704055] - Yoshihisa Kato, Koichi Haraguchi, Tomoaki Yamazaki, Ryohei Kimura, Nobuyuki Koga, Shizuo Yamada, Masakuni Degawa. The decrease in level of serum thyroxine by 2,2',4,5,5'-pentachlorobiphenyl in rats and mice: no correlation with formation of methylsulfonyl metabolites.
Drug metabolism and disposition: the biological fate of chemicals.
2005 Nov; 33(11):1661-5. doi:
10.1124/dmd.105.006189. [PMID: 16109825] - Koichi Haraguchi, Nobuyuki Koga, Yoshihisa Kato. Comparative metabolism of polychlorinated biphenyls and tissue distribution of persistent metabolites in rats, hamsters, and Guinea pigs.
Drug metabolism and disposition: the biological fate of chemicals.
2005 Mar; 33(3):373-80. doi:
10.1124/dmd.104.002444. [PMID: 15608140] - Hideki Fukata, Mariko Omori, Hisao Osada, Emiko Todaka, Chisato Mori. Necessity to measure PCBs and organochlorine pesticide concentrations in human umbilical cords for fetal exposure assessment.
Environmental health perspectives.
2005 Mar; 113(3):297-303. doi:
10.1289/ehp.7330. [PMID: 15743718] - K Haraguchi, Y Kato, N Koga, M Degawa. Species differences in the tissue distribution of catechol and methylsulphonyl metabolites of 2,4,5,2',5'-penta- and 2,3,4,2',3',6'-hexachlorobiphenyls in rats, mice, hamsters and guinea pigs.
Xenobiotica; the fate of foreign compounds in biological systems.
2005 Jan; 35(1):85-96. doi:
10.1080/00498250400026456. [PMID: 15788370] - Koichi Haraguchi, Yoshihisa Kato, Nobuyuki Koga, Masakuni Degawa. Metabolism of polychlorinated biphenyls by Gunn rats: identification and serum retention of catechol metabolites.
Chemical research in toxicology.
2004 Dec; 17(12):1684-91. doi:
10.1021/tx0498096. [PMID: 15606145] - Shaogang Chu, Adrian Covaci, Koichi Haraguchi, Stefan Voorspoels, Kristin Van de Vijver, Krishna Das, Jean-Marie Bouquegneau, Wim De Coen, Ronny Blust, Paul Schepens. Levels and enantiomeric signatures of methyl sulfonyl PCB and DDE metabolites in livers of harbor porpoises (Phocoena phocoena) from the Southern North Sea.
Environmental science & technology.
2003 Oct; 37(20):4573-8. doi:
10.1021/es034241t. [PMID: 14594363] - Shaogang Chu, Adrian Covaci, Werner Jacobs, Koichi Haraguchi, Paul Schepens. Distribution of methyl sulfone metabolites of polychlorinated biphenyls and p,p'-DDE in human tissues.
Environmental health perspectives.
2003 Jul; 111(9):1222-7. doi:
10.1289/ehp.6141. [PMID: 12842777] - Ji Y Zhang, Josh J Yuan, Yue-Fen Wang, Roy H Bible, Alan P Breau. Pharmacokinetics and metabolism of a COX-2 inhibitor, valdecoxib, in mice.
Drug metabolism and disposition: the biological fate of chemicals.
2003 Apr; 31(4):491-501. doi:
10.1124/dmd.31.4.491. [PMID: 12642477] - Dong-an Wang, Jian Ji, Yong-hong Sun, Jia-cong Shen, Lin-xian Feng, Jennifer H Elisseeff. In situ immobilization of proteins and RGD peptide on polyurethane surfaces via poly(ethylene oxide) coupling polymers for human endothelial cell growth.
Biomacromolecules.
2002 Nov; 3(6):1286-95. doi:
10.1021/bm0255950. [PMID: 12425667] - Stanley J Ulijaszek. Serum insulin-like growth factor-I, insulin-like growth factor binding protein-3, and the pubertal growth spurt in the female rhesus monkey.
American journal of physical anthropology.
2002 May; 118(1):77-85. doi:
10.1002/ajpa.10072. [PMID: 11953947]
