3-O-Methyl-d-glucose (BioDeep_00000840578)
代谢物信息卡片
3-O-Methyl-d-glucose
化学式: C7H14O6 (194.079)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC(C(C=O)O)C(C(CO)O)O
InChI: InChI=1S/C7H14O6/c1-13-7(5(11)3-9)6(12)4(10)2-8/h3-8,10-12H,2H2,1H3/t4-,5+,6-,7-/m1/s1
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Xiang Zhang, Zhiqiang Cheng, Shuohui Dong, Christopher Rayner, Tongzhi Wu, Mingwei Zhong, Guangyong Zhang, Kexin Wang, Sanyuan Hu. Effects of ileal glucose infusion on enteropancreatic hormone secretion in humans: relationship to glucose absorption.
Metabolism: clinical and experimental.
2022 06; 131(?):155198. doi:
10.1016/j.metabol.2022.155198. [PMID: 35395220] - Sarah K Kirschner, Nicolaas E P Deutz, Renate Jonker, Steven W M Olde Damink, Rajesh I Harrykissoon, Anthony J Zachria, Srinivasan Dasarathy, Mariëlle P K J Engelen. Intestinal function is impaired in patients with Chronic Obstructive Pulmonary Disease.
Clinical nutrition (Edinburgh, Scotland).
2021 04; 40(4):2270-2277. doi:
10.1016/j.clnu.2020.10.010. [PMID: 33873268] - Maryam Hajishafiee, Rachel A Elovaris, Karen L Jones, Leonie K Heilbronn, Michael Horowitz, Sally D Poppitt, Christine Feinle-Bisset. Effects of intragastric administration of L-tryptophan on the glycaemic response to a nutrient drink in men with type 2 diabetes - impacts on gastric emptying, glucoregulatory hormones and glucose absorption.
Nutrition & diabetes.
2021 01; 11(1):3. doi:
10.1038/s41387-020-00146-9. [PMID: 33414406] - Hung Pham, Iselin S Holen, Liza K Phillips, Seva Hatzinikolas, Lian Q Huynh, Tongzhi Wu, Trygve Hausken, Christopher K Rayner, Michael Horowitz, Karen L Jones. The Effects of a Whey Protein and Guar Gum-Containing Preload on Gastric Emptying, Glycaemia, Small Intestinal Absorption and Blood Pressure in Healthy Older Subjects.
Nutrients.
2019 Nov; 11(11):. doi:
10.3390/nu11112666. [PMID: 31694157] - Cintia Garro, Antonio Brun, William H Karasov, Enrique Caviedes-Vidal. Small intestinal epithelial permeability to water-soluble nutrients higher in passerine birds than in rodents.
Journal of animal physiology and animal nutrition.
2018 Dec; 102(6):1766-1773. doi:
10.1111/jpn.12969. [PMID: 30073711] - Gabriella A Heruc, Tanya J Little, Michael R Kohn, Sloane Madden, Simon D Clarke, Michael Horowitz, Christine Feinle-Bisset. Effects of starvation and short-term refeeding on gastric emptying and postprandial blood glucose regulation in adolescent girls with anorexia nervosa.
American journal of physiology. Endocrinology and metabolism.
2018 10; 315(4):E565-E573. doi:
10.1152/ajpendo.00149.2018. [PMID: 29969316] - Ofer Shamni, Guy Cohen, Arie Gruzman, Hilal Zaid, Amira Klip, Erol Cerasi, Shlomo Sasson. Regulation of GLUT4 activity in myotubes by 3-O-methyl-d-glucose.
Biochimica et biophysica acta. Biomembranes.
2017 Oct; 1859(10):1900-1910. doi:
10.1016/j.bbamem.2017.06.013. [PMID: 28648676] - Michael J Coady, Bernadette Wallendorff, Jean-Yves Lapointe. Characterization of the transport activity of SGLT2/MAP17, the renal low-affinity Na+-glucose cotransporter.
American journal of physiology. Renal physiology.
2017 Aug; 313(2):F467-F474. doi:
10.1152/ajprenal.00628.2016. [PMID: 28592437] - Tongzhi Wu, Cong Xie, Hang Wu, Karen L Jones, Michael Horowitz, Christopher K Rayner. Metformin reduces the rate of small intestinal glucose absorption in type 2 diabetes.
Diabetes, obesity & metabolism.
2017 02; 19(2):290-293. doi:
10.1111/dom.12812. [PMID: 27761984] - Sony S Thazhath, Tongzhi Wu, Michelle J Bound, Helen L Checklin, Scott Standfield, Karen L Jones, Michael Horowitz, Christopher K Rayner. Effects of intraduodenal hydroxycitrate on glucose absorption, incretin release, and glycemia in response to intraduodenal glucose infusion in health and type 2 diabetes: A randomised controlled trial.
Nutrition (Burbank, Los Angeles County, Calif.).
2016 May; 32(5):553-9. doi:
10.1016/j.nut.2015.11.004. [PMID: 26792024] - Palash Kar, Karen L Jones, Michael Horowitz, Marianne J Chapman, Adam M Deane. Measurement of gastric emptying in the critically ill.
Clinical nutrition (Edinburgh, Scotland).
2015 Aug; 34(4):557-64. doi:
10.1016/j.clnu.2014.11.003. [PMID: 25491245] - Robert L Dobbins, Frank L Greenway, Lihong Chen, Yaping Liu, Sharon L Breed, Susan M Andrews, Jeffrey A Wald, Ann Walker, Chari D Smith. Selective sodium-dependent glucose transporter 1 inhibitors block glucose absorption and impair glucose-dependent insulinotropic peptide release.
American journal of physiology. Gastrointestinal and liver physiology.
2015 Jun; 308(11):G946-54. doi:
10.1152/ajpgi.00286.2014. [PMID: 25767259] - Nam Q Nguyen, Tamara L Debreceni, Jenna E Bambrick, Bridgette Chia, Judith Wishart, Adam M Deane, Chris K Rayner, Michael Horowitz, Richard L Young. Accelerated intestinal glucose absorption in morbidly obese humans: relationship to glucose transporters, incretin hormones, and glycemia.
The Journal of clinical endocrinology and metabolism.
2015 Mar; 100(3):968-76. doi:
10.1210/jc.2014-3144. [PMID: 25423571] - Sibel Cetik, Aigun Rzajeva, Emeline Hupkens, Willy J Malaisse, Abdullah Sener. Uptake and metabolism of D-glucose in isolated acinar and ductal cells from rat submandibular glands.
Cell biochemistry and function.
2014 Jul; 32(5):470-5. doi:
10.1002/cbf.3039. [PMID: 24888554] - David L Sigalet, Dragan Kravarusic, Decker Butzner, Bolette Hartmann, Jens J Holst, Jon Meddings. A pilot study examining the relationship among Crohn disease activity, glucagon-like peptide-2 signalling and intestinal function in pediatric patients.
Canadian journal of gastroenterology = Journal canadien de gastroenterologie.
2013 Oct; 27(10):587-92. doi:
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Diabetes.
2013 Oct; 62(10):3532-41. doi:
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Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.
2013 Jan; 164(1):71-6. doi:
10.1016/j.cbpa.2012.09.008. [PMID: 23000883] - Anthony J Cura, Anthony Carruthers. AMP kinase regulation of sugar transport in brain capillary endothelial cells during acute metabolic stress.
American journal of physiology. Cell physiology.
2012 Oct; 303(8):C806-14. doi:
10.1152/ajpcell.00437.2011. [PMID: 22763120] - Sarunyoo Songkro, Maleewan Jenboonlap, Munchalee Boonprasertpon, Duangkhae Maneenuan, Khemmarat Bouking, Nattha Kaewnopparat. Effects of glucam P-20, vanillin, and fixolide on mosquito repellency of citronella oil lotions.
Journal of medical entomology.
2012 May; 49(3):672-7. doi:
10.1603/me11141. [PMID: 22679876] - Juan Gabriel Angeles-Núñez, Axel Tiessen. Regulation of AtSUS2 and AtSUS3 by glucose and the transcription factor LEC2 in different tissues and at different stages of Arabidopsis seed development.
Plant molecular biology.
2012 Mar; 78(4-5):377-92. doi:
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Critical care medicine.
2012 Jan; 40(1):50-4. doi:
10.1097/ccm.0b013e31822d71a6. [PMID: 21926614] - George G Schweitzer, Gregory D Cartee. Postexercise skeletal muscle glucose transport is normal in kininogen-deficient rats.
Medicine and science in sports and exercise.
2011 Jul; 43(7):1148-53. doi:
10.1249/mss.0b013e31820a7f65. [PMID: 21200341] - Paul Kuo, Max Bellon, Judith Wishart, André J Smout, Richard H Holloway, Robert J L Fraser, Michael Horowitz, Karen L Jones, Christopher K Rayner. Effects of metoclopramide on duodenal motility and flow events, glucose absorption, and incretin hormone release in response to intraduodenal glucose infusion.
American journal of physiology. Gastrointestinal and liver physiology.
2010 Dec; 299(6):G1326-33. doi:
10.1152/ajpgi.00476.2009. [PMID: 20829521] - Suenje Fischer, Anne Navarrete Santos, René Thieme, Nicole Ramin, Bernd Fischer. Adiponectin stimulates glucose uptake in rabbit blastocysts.
Biology of reproduction.
2010 Nov; 83(5):859-65. doi:
10.1095/biolreprod.110.084665. [PMID: 20686181] - Jing Ma, Jessica Chang, Helen L Checklin, Richard L Young, Karen L Jones, Michael Horowitz, Christopher K Rayner. Effect of the artificial sweetener, sucralose, on small intestinal glucose absorption in healthy human subjects.
The British journal of nutrition.
2010 Sep; 104(6):803-6. doi:
10.1017/s0007114510001327. [PMID: 20420761] - Adam M Deane, Marianne J Chapman, Robert J L Fraser, Matthew J Summers, Antony V Zaknic, James P Storey, Karen L Jones, Christopher K Rayner, Michael Horowitz. Effects of exogenous glucagon-like peptide-1 on gastric emptying and glucose absorption in the critically ill: relationship to glycemia.
Critical care medicine.
2010 May; 38(5):1261-9. doi:
10.1097/ccm.0b013e3181d9d87a. [PMID: 20228679] - Reinhard Duehlmeier, Anja Hacker, Andrea Widdel-Bigdely, Wolfgang von Engelhardt, Hans-Peter Sallmann. Insulin stimulates GLUT4 translocation in the semitendinosus muscle of Shetland ponies.
Veterinary journal (London, England : 1997).
2010 May; 184(2):176-81. doi:
10.1016/j.tvjl.2009.01.024. [PMID: 19278877] - Xiao Ma, Nobumasa Iwanaka, Shinya Masuda, Kouhei Karaike, Tatsuro Egawa, Taku Hamada, Taro Toyoda, Licht Miyamoto, Kazuwa Nakao, Tatsuya Hayashi. Morus alba leaf extract stimulates 5'-AMP-activated protein kinase in isolated rat skeletal muscle.
Journal of ethnopharmacology.
2009 Feb; 122(1):54-9. doi:
10.1016/j.jep.2008.11.022. [PMID: 19101621] - Dong Wang, Hong Yang, Lei Shi, Li Ma, Tatsuya Fujii, Kristin Engelstad, Juan M Pascual, Darryl C De Vivo. Functional studies of the T295M mutation causing Glut1 deficiency: glucose efflux preferentially affected by T295M.
Pediatric research.
2008 Nov; 64(5):538-43. doi:
10.1203/pdr.0b013e318184d2b5. [PMID: 18614966] - A N Sferruzzi-Perri, J A Owens, P Standen, C T Roberts. Maternal insulin-like growth factor-II promotes placental functional development via the type 2 IGF receptor in the guinea pig.
Placenta.
2008 Apr; 29(4):347-55. doi:
10.1016/j.placenta.2008.01.009. [PMID: 18339421] - Edward B Arias, Gregory D Cartee. In vitro simulation of calorie restriction-induced decline in glucose and insulin leads to increased insulin-stimulated glucose transport in rat skeletal muscle.
American journal of physiology. Endocrinology and metabolism.
2007 Dec; 293(6):E1782-8. doi:
10.1152/ajpendo.00531.2007. [PMID: 17925453] - Farah S L Thong, Jamie S V Lally, David J Dyck, Felicia Greer, Arend Bonen, Terry E Graham. Activation of the A1 adenosine receptor increases insulin-stimulated glucose transport in isolated rat soleus muscle.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.
2007 Aug; 32(4):701-10. doi:
10.1139/h07-039. [PMID: 17622285] - Reawika Chaikomin, Keng Liang Wu, Selena Doran, Karen L Jones, Andre J P M Smout, Willem Renooij, Richard H Holloway, James H Meyer, Michael Horowitz, Christopher K Rayner. Concurrent duodenal manometric and impedance recording to evaluate the effects of hyoscine on motility and flow events, glucose absorption, and incretin release.
American journal of physiology. Gastrointestinal and liver physiology.
2007 Apr; 292(4):G1099-104. doi:
10.1152/ajpgi.00519.2006. [PMID: 17204542] - Hakam Alkhateeb, Adrian Chabowski, Arend Bonen. Viability of the isolated soleus muscle during long-term incubation.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.
2006 Aug; 31(4):467-76. doi:
10.1139/h06-022. [PMID: 16900237] - David J Coman, K G Sinclair, C J Burke, D B Appleton, J T Pelekanos, C M O'Neil, G B Wallace, F G Bowling, D Wang, D C De Vivo, J J McGill. Seizures, ataxia, developmental delay and the general paediatrician: glucose transporter 1 deficiency syndrome.
Journal of paediatrics and child health.
2006 May; 42(5):263-7. doi:
10.1111/j.1440-1754.2006.00852.x. [PMID: 16712556] - María Cecilia Rauch, María Eliana Ocampo, Joanna Bohle, Rodolfo Amthauer, Alejandro J Yáñez, Joan E Rodríguez-Gil, Juan Carlos Slebe, Juan G Reyes, Ilona I Concha. Hexose transporters GLUT1 and GLUT3 are colocalized with hexokinase I in caveolae microdomains of rat spermatogenic cells.
Journal of cellular physiology.
2006 May; 207(2):397-406. doi:
10.1002/jcp.20582. [PMID: 16419038] - John X Wilson, Magdalena Dragan. Sepsis inhibits recycling and glutamate-stimulated export of ascorbate by astrocytes.
Free radical biology & medicine.
2005 Oct; 39(8):990-8. doi:
10.1016/j.freeradbiomed.2005.05.020. [PMID: 16198226] - E M Bingham, J T Dunn, D Smith, J Sutcliffe-Goulden, L J Reed, P K Marsden, S A Amiel. Differential changes in brain glucose metabolism during hypoglycaemia accompany loss of hypoglycaemia awareness in men with type 1 diabetes mellitus. An [11C]-3-O-methyl-D-glucose PET study.
Diabetologia.
2005 Oct; 48(10):2080-9. doi:
10.1007/s00125-005-1900-6. [PMID: 16143864] - Masanori Iwase, Udai Nakamura, Yuji Uchizono, Sakae Nohara, Nobuhiro Sasaki, Kazuo Sonoki, Mitsuo Iida. Nateglinide, a non-sulfonylurea rapid insulin secretagogue, increases pancreatic islet blood flow in rats.
European journal of pharmacology.
2005 Aug; 518(2-3):243-50. doi:
10.1016/j.ejphar.2005.05.044. [PMID: 16023099] - Reinhard Duhlmeier, Anja Hacker, Andrea Widdel, Wolfgang von Engelhardt, Hans-Peter Sallmann. Mechanisms of insulin-dependent glucose transport into porcine and bovine skeletal muscle.
American journal of physiology. Regulatory, integrative and comparative physiology.
2005 Jul; 289(1):R187-97. doi:
10.1152/ajpregu.00502.2004. [PMID: 15817843] - Tuansheng Shi, Jörg Schönherr, Lukas Schreiber. Accelerators increase permeability of cuticles for the lipophilic solutes metribuzin and iprovalicarb but not for hydrophilic methyl glucose.
Journal of agricultural and food chemistry.
2005 Apr; 53(7):2609-15. doi:
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Acta physiologica Scandinavica.
2005 Apr; 183(4):357-66. doi:
10.1111/j.1365-201x.2005.01408.x. [PMID: 15799772] - Frédéric Tremblay, AnneMarie Gagnon, Alain Veilleux, Alexander Sorisky, André Marette. Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes.
Endocrinology.
2005 Mar; 146(3):1328-37. doi:
10.1210/en.2004-0777. [PMID: 15576463] - L K Bryant, R J Fraser, R Vozzo, B Zacharakis, G M Matthews, R Butler. Stimulation of small intestinal burst activity in the postprandial state differentially affects lipid and glucose absorption in healthy adult humans.
American journal of physiology. Gastrointestinal and liver physiology.
2004 Nov; 287(5):G1028-34. doi:
10.1152/ajpgi.00091.2004. [PMID: 15191881] - Dorthe Villadsen, Steven M Smith. Identification of more than 200 glucose-responsive Arabidopsis genes none of which responds to 3-O-methylglucose or 6-deoxyglucose.
Plant molecular biology.
2004 Jul; 55(4):467-77. doi:
10.1007/s11103-004-1050-0. [PMID: 15604693] - David L Sigalet, Gary R Martin, Jon B Meddings. 3-0 methylglucose uptake as a marker of nutrient absorption and bowel length in pediatric patients.
JPEN. Journal of parenteral and enteral nutrition.
2004 May; 28(3):158-62. doi:
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The Journal of biological chemistry.
2004 Mar; 279(11):9703-12. doi:
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Experimental parasitology.
2004 Mar; 106(3-4):126-34. doi:
10.1016/j.exppara.2004.03.012. [PMID: 15172220] - Li-Bin Liu, Waka Omata, Itaru Kojima, Hiroshi Shibata. Insulin recruits GLUT4 from distinct compartments via distinct traffic pathways with differential microtubule dependence in rat adipocytes.
The Journal of biological chemistry.
2003 Aug; 278(32):30157-69. doi:
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Canadian journal of veterinary research = Revue canadienne de recherche veterinaire.
2003 May; 67(2):88-93. doi:
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Plant physiology.
2003 Feb; 131(2):824-37. doi:
10.1104/pp.010538. [PMID: 12586906] - Gary R Martin, Jonathan B Meddings, David L Sigalet. 3-0 methylglucose absorption in vivo correlates with nutrient absorption and intestinal surface area in experimental short bowel syndrome.
JPEN. Journal of parenteral and enteral nutrition.
2003 Jan; 27(1):65-70. doi:
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The American journal of gastroenterology.
2002 Dec; 97(12):3123-30. doi:
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Plant & cell physiology.
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Journal of veterinary internal medicine.
2002 Nov; 16(6):669-73. doi:
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Diabetes care.
2002 Oct; 25(10):1857-61. doi:
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Metabolism: clinical and experimental.
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Diabetes.
2002 Jul; 51(7):2199-206. doi:
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BMC plant biology.
2002 May; 2(?):4. doi:
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Growth factors (Chur, Switzerland).
2002 Mar; 20(1):17-25. doi:
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Journal of applied physiology (Bethesda, Md. : 1985).
2002 Feb; 92(2):657-64. doi:
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Plant molecular biology.
2001 Nov; 47(5):621-31. doi:
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Life sciences.
2001 Oct; 69(20):2383-98. doi:
10.1016/s0024-3205(01)01325-x. [PMID: 11681625] - D Y Hwang, F Ismail-Beigi. Stimulation of GLUT-1 glucose transporter expression in response to hyperosmolarity.
American journal of physiology. Cell physiology.
2001 Oct; 281(4):C1365-72. doi:
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Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
2001 Oct; 21(10):1160-70. doi:
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Biochimica et biophysica acta.
2001 Aug; 1520(2):174-8. doi:
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American journal of physiology. Renal physiology.
2001 Aug; 281(2):F374-80. doi:
10.1152/ajprenal.2001.281.2.f374. [PMID: 11457730] - Z Dagher, N Ruderman, K Tornheim, Y Ido. Acute regulation of fatty acid oxidation and amp-activated protein kinase in human umbilical vein endothelial cells.
Circulation research.
2001 Jun; 88(12):1276-82. doi:
10.1161/hh1201.092998. [PMID: 11420304] - E Debru, G R Martin, D L Sigalet. In vivo measurement of intestinal absorption using 3-0 methylglucose in short bowel syndrome.
Journal of pediatric surgery.
2001 May; 36(5):745-9. doi:
10.1053/jpsu.2001.22951. [PMID: 11329580] - D Topstad, G Martin, D Sigalet. Systemic GLP-2 levels do not limit adaptation after distal intestinal resection.
Journal of pediatric surgery.
2001 May; 36(5):750-4. doi:
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