Poacic acid (BioDeep_00000840542)
代谢物信息卡片
化学式: C19H18O6 (342.11033280000004)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC1=CC(=CC(=C1O)C=CC2=CC(=C(C=C2)O)OC)C=CC(=O)O
InChI: InChI=1S/C19H18O6/c1-24-16-10-12(4-7-15(16)20)3-6-14-9-13(5-8-18(21)22)11-17(25-2)19(14)23/h3-11,20,23H,1-2H3,(H,21,22)/b6-3+,8-5+
描述信息
A hydroxycinnamic acid that is (2E)-3-phenylprop-2-enoic acid in which the hydrogens at positions 3, 4 and 5 are replaced by 2-(4-hydroxy-3-methoxyphenyl)ethenyl, hydroxy and methoxy groups, respectively. It is a natural product found in maize bran which exhibits antifungal activities against several fungal and oomycete pathogens including Sclerotinia sclerotiorum, Alternaria solani, and Phytophthora sojae. It inhibits beta-1,3-glucan synthesis in cells walls resulting in rapid cell lysis.
同义名列表
1 个代谢物同义名
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:156511
- PubChem: 10337420
- ChEMBL: CHEMBL4218130
- CAS: 160097-32-5
- MetaboLights: MTBLC156511
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 265497 - Catalpa ovata: 10.1021/ACS.JNATPROD.7B00139
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Adi Yona, Micha Fridman. Poacic Acid, a Plant-Derived Stilbenoid, Augments Cell Wall Chitin Production, but Its Antifungal Activity Is Hindered by This Polysaccharide and by Fungal Essential Metals.
Biochemistry.
2024 Apr; 63(8):1051-1065. doi:
10.1021/acs.biochem.3c00595. [PMID: 38533731] - Raúl García, Kaori Itto-Nakama, José Manuel Rodríguez-Peña, Xiaolin Chen, Ana Belén Sanz, Alba de Lorenzo, Mónica Pavón-Vergés, Karen Kubo, Shinsuke Ohnuki, César Nombela, Laura Popolo, Yoshikazu Ohya, Javier Arroyo. Poacic acid, a β-1,3-glucan-binding antifungal agent, inhibits cell-wall remodeling and activates transcriptional responses regulated by the cell-wall integrity and high-osmolarity glycerol pathways in yeast.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2021 09; 35(9):e21778. doi:
10.1096/fj.202100278r. [PMID: 34383971] - Yun-Seo Kil, Seong Min Kim, Unwoo Kang, Hae Young Chung, Eun Kyoung Seo. Peroxynitrite-Scavenging Glycosides from the Stem Bark of Catalpa ovata.
Journal of natural products.
2017 08; 80(8):2240-2251. doi:
10.1021/acs.jnatprod.7b00139. [PMID: 28787158] - Jeff S Piotrowski, Hiroki Okada, Fachuang Lu, Sheena C Li, Li Hinchman, Ashish Ranjan, Damon L Smith, Alan J Higbee, Arne Ulbrich, Joshua J Coon, Raamesh Deshpande, Yury V Bukhman, Sean McIlwain, Irene M Ong, Chad L Myers, Charles Boone, Robert Landick, John Ralph, Mehdi Kabbage, Yoshikazu Ohya. Plant-derived antifungal agent poacic acid targets β-1,3-glucan.
Proceedings of the National Academy of Sciences of the United States of America.
2015 Mar; 112(12):E1490-7. doi:
10.1073/pnas.1410400112. [PMID: 25775513]