3alpha,7alpha,12alpha-Trihydroxy-5beta-cholan-24-oate (BioDeep_00000840541)
代谢物信息卡片
3alpha,7alpha,12alpha-Trihydroxy-5beta-cholan-24-oate
化学式: C24H39O5- (407.2797344)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(CCC(=O)[O-])C1CCC2C1(C(CC3C2C(CC4C3(CCC(C4)O)C)O)O)C
InChI: InChI=1S/C24H40O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29)/p-1/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-/m1/s1
描述信息
COVID info from COVID-19 Disease Map
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
同义名列表
相关代谢途径
Reactome(11)
- Metabolism
- Metabolism of proteins
- Post-translational protein modification
- Asparagine N-linked glycosylation
- Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
- Synthesis of substrates in N-glycan biosythesis
- Metabolism of lipids
- Metabolism of steroids
- Bile acid and bile salt metabolism
- Synthesis of bile acids and bile salts
- Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
PlantCyc(0)
代谢反应
67 个相关的代谢反应过程信息。
Reactome(66)
- Post-translational protein modification:
NAD + SPM ⟶ 1,3-diaminopropane + H+ + NADH - Metabolism of proteins:
EIF5A + NAD + SPM ⟶ 1,3-diaminopropane + EIF5A(Dhp) + H+ + NADH - Post-translational protein modification:
EIF5A + NAD + SPM ⟶ 1,3-diaminopropane + EIF5A(Dhp) + H+ + NADH - Asparagine N-linked glycosylation:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Synthesis of substrates in N-glycan biosythesis:
GlcNGc-6-P + H2O ⟶ CCA + GlcN6P - Synthesis of UDP-N-acetyl-glucosamine:
GlcNGc-6-P + H2O ⟶ CCA + GlcN6P - Metabolism of proteins:
NAD + SPM ⟶ 1,3-diaminopropane + H+ + NADH - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Asparagine N-linked glycosylation:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Synthesis of substrates in N-glycan biosythesis:
GlcNGc-6-P + H2O ⟶ CCA + GlcN6P - Synthesis of UDP-N-acetyl-glucosamine:
GlcNGc-6-P + H2O ⟶ CCA + GlcN6P - Metabolism of proteins:
EIF5A + NAD + SPM ⟶ 1,3-diaminopropane + EIF5A(Dhp) + H+ + NADH - Post-translational protein modification:
EIF5A + NAD + SPM ⟶ 1,3-diaminopropane + EIF5A(Dhp) + H+ + NADH - Asparagine N-linked glycosylation:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Synthesis of UDP-N-acetyl-glucosamine:
AcGlcN1P + UTP ⟶ PPi + UDP-GlcNAc - Synthesis of substrates in N-glycan biosythesis:
GlcNGc-6-P + H2O ⟶ CCA + GlcN6P - Synthesis of UDP-N-acetyl-glucosamine:
GlcNGc-6-P + H2O ⟶ CCA + GlcN6P - Metabolism of proteins:
NAD + SPM ⟶ 1,3-diaminopropane + H+ + NADH - Post-translational protein modification:
NAD + SPM ⟶ 1,3-diaminopropane + H+ + NADH - Asparagine N-linked glycosylation:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Synthesis of substrates in N-glycan biosythesis:
GlcNGc-6-P + H2O ⟶ CCA + GlcN6P - Synthesis of UDP-N-acetyl-glucosamine:
GlcNGc-6-P + H2O ⟶ CCA + GlcN6P - Metabolism of proteins:
EIF5A + NAD + SPM ⟶ 1,3-diaminopropane + H+ + NADH + Q9GU68 - Post-translational protein modification:
EIF5A + NAD + SPM ⟶ 1,3-diaminopropane + H+ + NADH + Q9GU68 - Asparagine N-linked glycosylation:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Synthesis of substrates in N-glycan biosythesis:
GlcNGc-6-P + H2O ⟶ CCA + GlcN6P - Synthesis of UDP-N-acetyl-glucosamine:
GlcNGc-6-P + H2O ⟶ CCA + GlcN6P - Metabolism of proteins:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Post-translational protein modification:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Asparagine N-linked glycosylation:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Synthesis of substrates in N-glycan biosythesis:
GlcNGc-6-P + H2O ⟶ CCA + GlcN6P - Synthesis of UDP-N-acetyl-glucosamine:
GlcNGc-6-P + H2O ⟶ CCA + GlcN6P - Metabolism of proteins:
EIF5A + NAD + SPM ⟶ 1,3-diaminopropane + EIF5A(Dhp) + H+ + NADH - Post-translational protein modification:
EIF5A + NAD + SPM ⟶ 1,3-diaminopropane + EIF5A(Dhp) + H+ + NADH - Asparagine N-linked glycosylation:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Synthesis of substrates in N-glycan biosythesis:
GlcNGc-6-P + H2O ⟶ CCA + GlcN6P - Synthesis of UDP-N-acetyl-glucosamine:
GlcNGc-6-P + H2O ⟶ CCA + GlcN6P - Metabolism of proteins:
EIF5A + NAD + SPM ⟶ 1,3-diaminopropane + EIF5A(Dhp) + H+ + NADH - Post-translational protein modification:
EIF5A + NAD + SPM ⟶ 1,3-diaminopropane + EIF5A(Dhp) + H+ + NADH - Asparagine N-linked glycosylation:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Synthesis of substrates in N-glycan biosythesis:
GlcNGc-6-P + H2O ⟶ CCA + GlcN6P - Synthesis of UDP-N-acetyl-glucosamine:
GlcNGc-6-P + H2O ⟶ CCA + GlcN6P - Metabolism of proteins:
EIF5A + NAD + SPM ⟶ 1,3-diaminopropane + EIF5A(Dhp) + H+ + NADH - Post-translational protein modification:
EIF5A + NAD + SPM ⟶ 1,3-diaminopropane + EIF5A(Dhp) + H+ + NADH - Asparagine N-linked glycosylation:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Synthesis of substrates in N-glycan biosythesis:
GlcNGc-6-P + H2O ⟶ CCA + GlcN6P - Synthesis of UDP-N-acetyl-glucosamine:
GlcNGc-6-P + H2O ⟶ CCA + GlcN6P - Metabolism of proteins:
EIF5A + NAD + SPM ⟶ 1,3-diaminopropane + EIF5A(Dhp) + H+ + NADH - Post-translational protein modification:
EIF5A + NAD + SPM ⟶ 1,3-diaminopropane + EIF5A(Dhp) + H+ + NADH - Asparagine N-linked glycosylation:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Synthesis of substrates in N-glycan biosythesis:
GlcNGc-6-P + H2O ⟶ CCA + GlcN6P - Synthesis of UDP-N-acetyl-glucosamine:
GlcNGc-6-P + H2O ⟶ CCA + GlcN6P - Metabolism of proteins:
NAD + SPM + eif5a ⟶ 1,3-diaminopropane + H+ + NADH + eif5a - Post-translational protein modification:
NAD + SPM + eif5a ⟶ 1,3-diaminopropane + H+ + NADH + eif5a - Asparagine N-linked glycosylation:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein:
DOLP + UDP-GlcNAc ⟶ GlcNAcDOLDP + UMP - Synthesis of substrates in N-glycan biosythesis:
ATP + MVA5PP ⟶ ADP + IPPP + Pi + carbon dioxide
BioCyc(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Frederik G Tidemand, Sara Blemmer, Nicolai T Johansen, Lise Arleth, Martin Cramer Pedersen. Non-ionic detergent assists formation of supercharged nanodiscs and insertion of membrane proteins.
Biochimica et biophysica acta. Biomembranes.
2022 06; 1864(6):183884. doi:
10.1016/j.bbamem.2022.183884. [PMID: 35182589] - Juntao Yin, Yantao Hou, Xiaoyong Song, Peiqing Wang, Yang Li. Cholate-modified polymer-lipid hybrid nanoparticles for oral delivery of quercetin to potentiate the antileukemic effect.
International journal of nanomedicine.
2019; 14(?):4045-4057. doi:
10.2147/ijn.s210057. [PMID: 31213814] - Yoichiro Asai, Tetsuya Yamada, Sohei Tsukita, Kei Takahashi, Masamitsu Maekawa, Midori Honma, Masanori Ikeda, Keigo Murakami, Yuichiro Munakata, Yuta Shirai, Shinjiro Kodama, Takashi Sugisawa, Yumiko Chiba, Yasuteru Kondo, Keizo Kaneko, Kenji Uno, Shojiro Sawada, Junta Imai, Yasuhiro Nakamura, Hiroaki Yamaguchi, Kozo Tanaka, Hironobu Sasano, Nariyasu Mano, Yoshiyuki Ueno, Tooru Shimosegawa, Hideki Katagiri. Activation of the Hypoxia Inducible Factor 1α Subunit Pathway in Steatotic Liver Contributes to Formation of Cholesterol Gallstones.
Gastroenterology.
2017 05; 152(6):1521-1535.e8. doi:
10.1053/j.gastro.2017.01.001. [PMID: 28088462] - Roshan W Gunasekara, Yan Zhao. Conformationally switchable water-soluble fluorescent bischolate foldamers as membrane-curvature sensors.
Langmuir : the ACS journal of surfaces and colloids.
2015 Apr; 31(13):3919-25. doi:
10.1021/acs.langmuir.5b00379. [PMID: 25782344] - Lin Yang, Feifei Feng, J Paul Fawcett, Ian G Tucker. Kinetic and equilibrium studies of bile salt-liposome interactions.
Journal of liposome research.
2015 Mar; 25(1):58-66. doi:
10.3109/08982104.2014.928888. [PMID: 24960448] - Lakmini Widanapathirana, Yan Zhao. Tuning nanopore formation of oligocholate macrocycles by carboxylic acid dimerization in lipid membranes.
The Journal of organic chemistry.
2013 May; 78(9):4610-4. doi:
10.1021/jo400455x. [PMID: 23578030] - Tuo Wang, Lakmini Widanapathirana, Yan Zhao, Mei Hong. Aggregation and dynamics of oligocholate transporters in phospholipid bilayers revealed by solid-state NMR spectroscopy.
Langmuir : the ACS journal of surfaces and colloids.
2012 Dec; 28(49):17071-8. doi:
10.1021/la303661p. [PMID: 23153411] - Gong Chen, Lin Yang, Hu Zhang, Ian G Tucker, J Paul Fawcett. Effect of ketocholate derivatives on methotrexate uptake in Caco-2 cell monolayers.
International journal of pharmaceutics.
2012 Aug; 433(1-2):89-93. doi:
10.1016/j.ijpharm.2012.04.077. [PMID: 22575673] - Lakmini Widanapathirana, Xueshu Li, Yan Zhao. Hydrogen bond-assisted macrocyclic oligocholate transporters in lipid membranes.
Organic & biomolecular chemistry.
2012 Jul; 10(26):5077-83. doi:
10.1039/c2ob25301a. [PMID: 22627275] - Lakmini Widanapathirana, Yan Zhao. Effects of amphiphile topology on the aggregation of oligocholates in lipid membranes: macrocyclic versus linear amphiphiles.
Langmuir : the ACS journal of surfaces and colloids.
2012 May; 28(21):8165-73. doi:
10.1021/la301090t. [PMID: 22563986] - Lakmini Widanapathirana, Yan Zhao. Aromatically functionalized cyclic tricholate macrocycles: aggregation, transmembrane pore formation, flexibility, and cooperativity.
The Journal of organic chemistry.
2012 May; 77(10):4679-87. doi:
10.1021/jo3004056. [PMID: 22524459] - Shiyong Zhang, Yan Zhao. Flexible oligocholate foldamers as membrane transporters and their guest-dependent transport mechanism.
Organic & biomolecular chemistry.
2012 Jan; 10(2):260-6. doi:
10.1039/c1ob06364b. [PMID: 22068436] - Nicholas N Lyssenko, Gregory Brubaker, Bradley D Smith, Jonathan D Smith. A novel compound inhibits reconstituted high-density lipoprotein assembly and blocks nascent high-density lipoprotein biogenesis downstream of apolipoprotein AI binding to ATP-binding cassette transporter A1-expressing cells.
Arteriosclerosis, thrombosis, and vascular biology.
2011 Nov; 31(11):2700-6. doi:
10.1161/atvbaha.111.234906. [PMID: 21836073] - Shiyong Zhang, Yan Zhao. Oligocholate foldamers as carriers for hydrophilic molecules across lipid bilayers.
Chemistry (Weinheim an der Bergstrasse, Germany).
2011 Oct; 17(44):12444-51. doi:
10.1002/chem.201101510. [PMID: 21935998] - Hongkwan Cho, Yan Zhao. Cholate-derived amphiphilic molecular baskets as glucose transporters across lipid membranes.
Chemical communications (Cambridge, England).
2011 Aug; 47(31):8970-2. doi:
10.1039/c1cc00092f. [PMID: 21698316] - Lu Peng, Richard A Hiipakka, Jing-Tian Xie, John M Kokontis, Shutsung Liao, Dacheng Peng. The effect of diet on the response of low-density lipoprotein receptor knockout mice to the liver X receptor agonist T1317.
Journal of cardiovascular pharmacology.
2011 Jul; 58(1):102-10. doi:
10.1097/fjc.0b013e31821d1168. [PMID: 21558881] - Hongkwan Cho, Yan Zhao. Translocation of hydrophilic molecules across lipid bilayers by salt-bridged oligocholates.
Langmuir : the ACS journal of surfaces and colloids.
2011 Apr; 27(8):4936-44. doi:
10.1021/la2005166. [PMID: 21446684] - Craig P Wilson, Cécile Boglio, Long Ma, Scott L Cockroft, Simon J Webb. Palladium(II)-mediated assembly of biotinylated ion channels.
Chemistry (Weinheim an der Bergstrasse, Germany).
2011 Mar; 17(12):3465-73. doi:
10.1002/chem.201002031. [PMID: 21328491] - Hongkwan Cho, Lakmini Widanapathirana, Yan Zhao. Water-templated transmembrane nanopores from shape-persistent oligocholate macrocycles.
Journal of the American Chemical Society.
2011 Jan; 133(1):141-7. doi:
10.1021/ja109036z. [PMID: 21142045] - Mustafa M A Elsayed, Gregor Cevc. The vesicle-to-micelle transformation of phospholipid-cholate mixed aggregates: a state of the art analysis including membrane curvature effects.
Biochimica et biophysica acta.
2011 Jan; 1808(1):140-53. doi:
10.1016/j.bbamem.2010.09.002. [PMID: 20832388] - Filippo Naso, Alessandro Gandaglia, Marilena Formato, Antonio Cigliano, Antonio J Lepedda, Gino Gerosa, Michel Spina. Differential distribution of structural components and hydration in aortic and pulmonary heart valve conduits: Impact of detergent-based cell removal.
Acta biomaterialia.
2010 Dec; 6(12):4675-88. doi:
10.1016/j.actbio.2010.06.037. [PMID: 20620247] - Makoto Yoshimoto, Noriyuki Takaki, Miku Yamasaki. Catalase-conjugated liposomes encapsulating glucose oxidase for controlled oxidation of glucose with decomposition of hydrogen peroxide produced.
Colloids and surfaces. B, Biointerfaces.
2010 Sep; 79(2):403-8. doi:
10.1016/j.colsurfb.2010.05.006. [PMID: 20537512] - Hongkwan Cho, Yan Zhao. Environmental effects dominate the folding of oligocholates in solution, surfactant micelles, and lipid membranes.
Journal of the American Chemical Society.
2010 Jul; 132(28):9890-9. doi:
10.1021/ja103694p. [PMID: 20572678] - Fabiana Zanelato Bertolde, Alex-Alan Furtado De Almeida, Ronan Xavier Corrêa, Fábio Pinto Gomes, Fernanda Amato Gaiotto, Virupax C Baligar, Leandro Lopes Loguercio. Molecular, physiological and morphological analysis of waterlogging tolerance in clonal genotypes of Theobroma cacao L.
Tree physiology.
2010 Jan; 30(1):56-67. doi:
10.1093/treephys/tpp101. [PMID: 19959598] - Kazumi Shimono, Mie Goto, Takashi Kikukawa, Seiji Miyauchi, Mikako Shirouzu, Naoki Kamo, Shigeyuki Yokoyama. Production of functional bacteriorhodopsin by an Escherichia coli cell-free protein synthesis system supplemented with steroid detergent and lipid.
Protein science : a publication of the Protein Society.
2009 Oct; 18(10):2160-71. doi:
10.1002/pro.230. [PMID: 19746358] - Yangchao Luo, Gang Chen, Bo Li, Baoping Ji, Zhenlei Xiao, Guo Yi, Fang Tian. Dietary intervention with AHP, a functional formula diet, improves both serum and hepatic lipids profile in dyslipidemia mice.
Journal of food science.
2009 Aug; 74(6):H189-95. doi:
10.1111/j.1750-3841.2009.01241.x. [PMID: 19723204] - Alexandra C Provost, Leonie Vede, Karine Bigot, Nicole Keller, Anne Tailleux, Jean-Philipe Jaïs, Michelle Savoldelli, Ilhame Ameqrane, Emmanuelle Lacassagne, Jean-Marc Legeais, Bart Staels, Maurice Menasche, Ziad Mallat, Francine Behar-Cohen, Marc Abitbol. Morphologic and electroretinographic phenotype of SR-BI knockout mice after a long-term atherogenic diet.
Investigative ophthalmology & visual science.
2009 Aug; 50(8):3931-42. doi:
10.1167/iovs.08-2527. [PMID: 19420333] - Craig D Blanchette, Brent W Segelke, Nicholas Fischer, Michele H Corzett, Edward A Kuhn, Jenny A Cappuccio, William Henry Benner, Matthew A Coleman, Brett A Chromy, Graham Bench, Paul D Hoeprich, Todd A Sulchek. Characterization and purification of polydisperse reconstituted lipoproteins and nanolipoprotein particles.
International journal of molecular sciences.
2009 Jul; 10(7):2958-2971. doi:
10.3390/ijms10072958. [PMID: 19742178] - Bin Chen, Xuefeng Ren, Tracey Neville, W Gray Jerome, David W Hoyt, Daniel Sparks, Gang Ren, Jianjun Wang. Apolipoprotein AI tertiary structures determine stability and phospholipid-binding activity of discoidal high-density lipoprotein particles of different sizes.
Protein science : a publication of the Protein Society.
2009 May; 18(5):921-35. doi:
10.1002/pro.101. [PMID: 19384992] - Ayman K Hamouda, David C Chiara, Michael P Blanton, Jonathan B Cohen. Probing the structure of the affinity-purified and lipid-reconstituted torpedo nicotinic acetylcholine receptor.
Biochemistry.
2008 Dec; 47(48):12787-94. doi:
10.1021/bi801476j. [PMID: 18991407] - Zh B Dashinamzhilov. [Effect of phytopreparation Narcophyt on choleretic reaction in white rats with experimental hepatitis].
Eksperimental'naia i klinicheskaia farmakologiia.
2008 Sep; 71(5):28-31. doi:
". [PMID: 19093368] - James R Reed, Lauren M Brignac-Huber, Wayne L Backes. Physical incorporation of NADPH-cytochrome P450 reductase and cytochrome P450 into phospholipid vesicles using glycocholate and Bio-Beads.
Drug metabolism and disposition: the biological fate of chemicals.
2008 Mar; 36(3):582-8. doi:
10.1124/dmd.107.018473. [PMID: 18048487] - James A Lin, Junji Watanabe, Nora Rozengurt, Ajay Narasimha, Martin G Martin, Jenny Wang, Jonathan Braun, Robert Langenbach, Srinivasa T Reddy. Atherogenic diet causes lethal ileo-ceco-colitis in cyclooxygenase-2 deficient mice.
Prostaglandins & other lipid mediators.
2007 Nov; 84(3-4):98-107. doi:
10.1016/j.prostaglandins.2007.04.004. [PMID: 17991612] - Amy Y Shih, Peter L Freddolino, Stephen G Sligar, Klaus Schulten. Disassembly of nanodiscs with cholate.
Nano letters.
2007 Jun; 7(6):1692-6. doi:
10.1021/nl0706906. [PMID: 17503871] - Timothy H Bayburt, Yelena V Grinkova, Stephen G Sligar. Assembly of single bacteriorhodopsin trimers in bilayer nanodiscs.
Archives of biochemistry and biophysics.
2006 Jun; 450(2):215-22. doi:
10.1016/j.abb.2006.03.013. [PMID: 16620766] - James R Reed, Rusty W Kelley, Wayne L Backes. An evaluation of methods for the reconstitution of cytochromes P450 and NADPH P450 reductase into lipid vesicles.
Drug metabolism and disposition: the biological fate of chemicals.
2006 Apr; 34(4):660-6. doi:
10.1124/dmd.105.006825. [PMID: 16415125] - J Karlovská, D Uhríková, N Kucerka, J Teixeira, F Devínsky, I Lacko, P Balgavý. Influence of N-dodecyl-N,N-dimethylamine N-oxide on the activity of sarcoplasmic reticulum Ca(2+)-transporting ATPase reconstituted into diacylphosphatidylcholine vesicles: efects of bilayer physical parameters.
Biophysical chemistry.
2006 Jan; 119(1):69-77. doi:
10.1016/j.bpc.2005.09.007. [PMID: 16223561] - Joo-Yeon Jung, Sun-Mee Lee. The roles of Kupffer cells in hepatic dysfunction induced by ischemia/reperfusion in rats.
Archives of pharmacal research.
2005 Dec; 28(12):1386-91. doi:
10.1007/bf02977906. [PMID: 16392673] - Silvia Arteaga, Agustín Carmona, Juana Luis, Adolfo Andrade-Cetto, René Cárdenas. Effect of Larrea tridentata (creosote bush) on cholesterol gallstones and bile secretion in hamsters.
The Journal of pharmacy and pharmacology.
2005 Sep; 57(9):1093-9. doi:
10.1211/jpp.57.9.0004. [PMID: 16105230] - Salvatore Chiantia, Libero I Giannola, Lorenzo Cordone. Lipid phase transition in saccharide-coated cholate-containing liposomes: coupling to the surrounding matrix.
Langmuir : the ACS journal of surfaces and colloids.
2005 Apr; 21(9):4108-16. doi:
10.1021/la046974c. [PMID: 15835981] - S I Simões, C M Marques, M E M Cruz, G Cevc, M B F Martins. The effect of cholate on solubilisation and permeability of simple and protein-loaded phosphatidylcholine/sodium cholate mixed aggregates designed to mediate transdermal delivery of macromolecules.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2004 Nov; 58(3):509-19. doi:
10.1016/j.ejpb.2004.05.010. [PMID: 15451525] - Lei Zhao, Michael P W Moos, Rolf Gräbner, Frédérique Pédrono, Jinjin Fan, Brigitte Kaiser, Nicole John, Sandra Schmidt, Rainer Spanbroek, Katharina Lötzer, Li Huang, Jisong Cui, Daniel J Rader, Jilly F Evans, Andreas J R Habenicht, Colin D Funk. The 5-lipoxygenase pathway promotes pathogenesis of hyperlipidemia-dependent aortic aneurysm.
Nature medicine.
2004 Sep; 10(9):966-73. doi:
10.1038/nm1099. [PMID: 15322539] - Miranda Van Eck, I Sophie T Bos, Reeni B Hildebrand, Brechje T Van Rij, Theo J C Van Berkel. Dual role for scavenger receptor class B, type I on bone marrow-derived cells in atherosclerotic lesion development.
The American journal of pathology.
2004 Sep; 165(3):785-94. doi:
10.1016/s0002-9440(10)63341-x. [PMID: 15331403] - Hyun Jung Kim, Soon-Ho Yim, Ik-Soo Lee. A cholesterol biosynthesis inhibitor from Rhizopus oryzae.
Archives of pharmacal research.
2004 Jun; 27(6):624-7. doi:
10.1007/bf02980161. [PMID: 15283464] - Aleksandar Raskovic, Vida Jakovljevic, Momir Mikov, Maja Gavrilovic. Joint effect of commercial preparations of Stevia rebaudiana Bertoni and sodium monoketocholate on glycemia in mice.
European journal of drug metabolism and pharmacokinetics.
2004 Apr; 29(2):83-6. doi:
10.1007/bf03190580. [PMID: 15230334] - Philip W Connelly, Graham F Maguire, Dragomir I Draganov. Separation and quantitative recovery of mouse serum arylesterase and carboxylesterase activity.
Journal of lipid research.
2004 Mar; 45(3):561-6. doi:
10.1194/jlr.m300464-jlr200. [PMID: 14703510] - Makoto Yoshimoto, Shaoqing Wang, Kimitoshi Fukunaga, Mike Treyer, Peter Walde, Ryoichi Kuboi, Katsumi Nakao. Enhancement of apparent substrate selectivity of proteinase K encapsulated in liposomes through a cholate-induced alteration of the bilayer permeability.
Biotechnology and bioengineering.
2004 Jan; 85(2):222-33. doi:
10.1002/bit.10891. [PMID: 14705005] - Laurent Vergnes, Jack Phan, Merav Strauss, Sherrie Tafuri, Karen Reue. Cholesterol and cholate components of an atherogenic diet induce distinct stages of hepatic inflammatory gene expression.
The Journal of biological chemistry.
2003 Oct; 278(44):42774-84. doi:
10.1074/jbc.m306022200. [PMID: 12923166] - B Pradines, J M Rolain, F Ramiandrasoa, T Fusai, J Mosnier, C Rogier, W Daries, E Baret, G Kunesch, J Le Bras, D Parzy. Iron chelators as antimalarial agents: in vitro activity of dicatecholate against Plasmodium falciparum.
The Journal of antimicrobial chemotherapy.
2002 Aug; 50(2):177-87. doi:
10.1093/jac/dkf104. [PMID: 12161397] - R A Srivastava, M Averna, N Srivastava, M E Pape. Dietary cholate increases plasma levels of apolipoprotein B in mice by posttranscriptional mechanisms.
The international journal of biochemistry & cell biology.
2001 Dec; 33(12):1215-26. doi:
10.1016/s1357-2725(01)00080-2. [PMID: 11606258] - X Gui, R E Carraway. Enhancement of jejunal absorption of conjugated bile acid by neurotensin in rats.
Gastroenterology.
2001 Jan; 120(1):151-60. doi:
10.1053/gast.2001.20876. [PMID: 11208724] - J M De Vree, R Ottenhoff, P J Bosma, A J Smith, J Aten, R P Oude Elferink. Correction of liver disease by hepatocyte transplantation in a mouse model of progressive familial intrahepatic cholestasis.
Gastroenterology.
2000 Dec; 119(6):1720-30. doi:
10.1053/gast.2000.20222. [PMID: 11113093] - E A Murphy, A J Waring, S M Haynes, K J Longmuir. Compaction of DNA in an anionic micelle environment followed by assembly into phosphatidylcholine liposomes.
Nucleic acids research.
2000 Aug; 28(15):2986-92. doi:
10.1093/nar/28.15.2986. [PMID: 10908363] - A H Lichtman, S K Clinton, K Iiyama, P W Connelly, P Libby, M I Cybulsky. Hyperlipidemia and atherosclerotic lesion development in LDL receptor-deficient mice fed defined semipurified diets with and without cholate.
Arteriosclerosis, thrombosis, and vascular biology.
1999 Aug; 19(8):1938-44. doi:
10.1161/01.atv.19.8.1938. [PMID: 10446074] - M B Jones, J C Garrison. Instability of the G-protein beta5 subunit in detergent.
Analytical biochemistry.
1999 Mar; 268(1):126-33. doi:
10.1006/abio.1998.3064. [PMID: 10036171] - M C Houbiers, R B Spruijt, C J Wolfs, M A Hemminga. Conformational and aggregational properties of the gene 9 minor coat protein of bacteriophage M13 in membrane-mimicking systems.
Biochemistry.
1999 Jan; 38(3):1128-35. doi:
10.1021/bi981149e. [PMID: 9894010] - N R Koopen, S M Post, H Wolters, R Havinga, F Stellaard, R Boverhof, F Kuipers, H M Princen. Differential effects of 17alpha-ethinylestradiol on the neutral and acidic pathways of bile salt synthesis in the rat.
Journal of lipid research.
1999 Jan; 40(1):100-8. doi:
10.1016/s0022-2275(20)33344-7. [PMID: 9869655] - M Schwarz, D W Russell, J M Dietschy, S D Turley. Marked reduction in bile acid synthesis in cholesterol 7alpha-hydroxylase-deficient mice does not lead to diminished tissue cholesterol turnover or to hypercholesterolemia.
Journal of lipid research.
1998 Sep; 39(9):1833-43. doi:
10.1016/s0022-2275(20)32171-4. [PMID: 9741696] - C R SESKIND, V R WHEATLEY, R A RASMUSSEN, R W WISSLER. Serum lipid analyses in rats fed natural and hydrogenated cottonseed oil with cholesterol and cholate.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.).
1959 Oct; 102(?):90-5. doi:
10.3181/00379727-102-25153. [PMID: 14445159] - H J RADERECHT, D SUCKROW, E SCHOELZEL. [On the influencing of lipase activity by buffer, cholate and lipid].
Acta biologica et medica Germanica.
1959; 3(?):461-9. doi:
". [PMID: 14435705] - J H ANNEGERS. Absorption of lipid and cholate from ileal loops in unanesthetized dogs.
The American journal of physiology.
1957 Oct; 191(1):75-80. doi:
10.1152/ajplegacy.1957.191.1.75. [PMID: 13478688] - M FRIEDMAN, R BINE, T ISHIDA. Removal of excess cholesterol and cholate by the isolated rat liver from its perfusate.
The American journal of physiology.
1956 Feb; 184(2):412-4. doi:
10.1152/ajplegacy.1956.184.2.412. [PMID: 13302435]