Atrinositol (BioDeep_00000840449)
代谢物信息卡片
Atrinositol
化学式: C6H15O15P3 (419.96238300000005)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1(C(C(C(C(C1O)OP(=O)(O)O)OP(=O)(O)O)OP(=O)(O)O)O)O
InChI: InChI=1S/C6H15O15P3/c7-1-2(8)4(19-22(10,11)12)6(21-24(16,17)18)5(3(1)9)20-23(13,14)15/h1-9H,(H2,10,11,12)(H2,13,14,15)(H2,16,17,18)/t1?,2-,3+,4-,5-,6?/m1/s1
描述信息
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
C78275 - Agent Affecting Blood or Body Fluid > C1327 - Antiplatelet Agent
D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors
D002491 - Central Nervous System Agents > D000700 - Analgesics
D000893 - Anti-Inflammatory Agents
D018501 - Antirheumatic Agents
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Feng Wang, Jörgen Larsson, Margery K Herrington, Johan Permert. PP56 improves energy homeostasis in a mouse model of pancreatic cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.
2010 Aug; 31(4):309-13. doi:
10.1007/s13277-010-0038-4. [PMID: 20422342] - S T Russell, P M A Siren, M J Siren, M J Tisdale. The role of zinc in the anti-tumour and anti-cachectic activity of D-myo-inositol 1,2,6-triphosphate.
British journal of cancer.
2010 Mar; 102(5):833-6. doi:
10.1038/sj.bjc.6605562. [PMID: 20145616] - Matti J Sirén, Maija Vainiomäki, Kalervo Väänänen, Pirkko Härkönen. alpha-Trinositol inhibits FGF-stimulated growth of smooth muscle and breast cancer cells.
Biochemical and biophysical research communications.
2004 Dec; 325(3):691-7. doi:
10.1016/j.bbrc.2004.10.087. [PMID: 15541344] - M Farstad, J K Heltne, S E Rynning, H Onarheim, A Mongstad, F Eliassen, P Husby. Can the use of methylprednisolone, vitamin C, or alpha-trinositol prevent cold-induced fluid extravasation during cardiopulmonary bypass in piglets?.
The Journal of thoracic and cardiovascular surgery.
2004 Feb; 127(2):525-34. doi:
10.1016/s0022-5223(03)01028-6. [PMID: 14762364] - Torbjørn Nedrebø, Rolf K Reed, Ansgar Berg. Effect of alpha-trinositol on interstitial fluid pressure, edema generation, and albumin extravasation after ischemia-reperfusion injury in rat hind limb.
Shock (Augusta, Ga.).
2003 Aug; 20(2):149-53. doi:
10.1097/01.shk.0000072128.33223.15. [PMID: 12865659] - R K Reed, E J Westerberg. Effect of alpha-trinositol on carrageenan-induced rat paw edema and lowering of interstitial fluid pressure.
European journal of pharmacology.
1999 Jul; 376(3):279-84. doi:
10.1016/s0014-2999(99)00364-7. [PMID: 10448888] - A Berg, P Aas, T Gustafsson, R K Reed. Effect of alpha-trinositol on interstitial fluid pressure, oedema generation and albumin extravasation in experimental frostbite in the rat.
British journal of pharmacology.
1999 Mar; 126(6):1367-74. doi:
10.1038/sj.bjp.0702442. [PMID: 10217530] - P Tarnow, A Jönsson, U Mattsson, G Rimbäck, J Cassuto. Inhibition of plasma extravasation after burns by D-myo-inositol-1,2,6-trisphosphate using digital image colour analysis.
Scandinavian journal of plastic and reconstructive surgery and hand surgery.
1998 Jun; 32(2):141-6. doi:
10.1080/02844319850158750. [PMID: 9646362] - L Nilsson, J Apelqvist, L Edvinsson. Effects of alpha-trinositol on peripheral circulation in diabetic patients with critical limb ischaemia. A pilot study using laser Doppler fluxmetry, transcutaneous oxygen tension measurements and dynamic capillaroscopy.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery.
1998 Apr; 15(4):331-6. doi:
10.1016/s1078-5884(98)80037-3. [PMID: 9610346] - J J Ferrara, E L Kukuy, D A Gilman, E U Choe, E W Franklin, L M Flint. Alpha-trinositol reduces edema formation at the site of scald injury.
Surgery.
1998 Jan; 123(1):36-45. doi:
10.1016/s0039-6060(98)70226-0. [PMID: 9457221] - E Brailoiu, A Margineanu, C P Toma, C M Filipeanu, V Rusu, D D Branisteanu. D-myo-inositol derivatives alter liposomal membrane fluidity.
Biochemistry and molecular biology international.
1998 Jan; 44(1):195-201. doi:
10.1080/15216549800201212. [PMID: 9503163] - W Lingnau, R McGuire, M Booke, L D Traber, D L Traber. Effects of alpha-trinositol on systemic inflammation and renal function in ovine bacterial sepsis.
Shock (Augusta, Ga.).
1997 Sep; 8(3):179-85. doi:
10.1097/00024382-199709000-00005. [PMID: 9377164] - E Brailoiu, C Beschea, C Brailoiu, A Costuleanu, C M Filipeanu, M Costuleanu, B Fallgren, D D Branisteanu. TLC characterization of small unilamellar liposomes containing D-myo-inositol derivatives.
Biomedical chromatography : BMC.
1996 Sep; 10(5):233-6. doi:
10.1002/(sici)1099-0801(199609)10:5<233::aid-bmc594>3.0.co;2-5. [PMID: 8879530] - R Stricker, E Westerberg, G Reiser. Binding sites for alpha-trinositol (inositol 1,2,6-trisphosphate) in porcine tissues; comparison with Ins(1,4,5)P3 and Ins(1,3,4,5)P4-binding sites.
British journal of pharmacology.
1996 Mar; 117(5):919-25. doi:
10.1111/j.1476-5381.1996.tb15281.x. [PMID: 8851511] - B A Buscher, U R Tjaden, H Irth, E M Andersson, J van der Greef. Determination of 1,2,6-inositol trisphosphate (derivatives) in plasma using iron(III)-loaded adsorbents and capillary zone electrophoresis-(indirect) UV detection.
Journal of chromatography. A.
1995 Dec; 718(2):413-9. doi:
10.1016/0021-9673(95)00701-6. [PMID: 8589823] - E Brailoiu, G Huhurez, S Slatineanu, C M Filipeanu, M Costuleanu, D D Branisteanu. TLC characterization of liposomes containing D-myo-inositol derivatives.
Biomedical chromatography : BMC.
1995 Jul; 9(4):175-8. doi:
10.1002/bmc.1130090405. [PMID: 8520206] - X Y Sun, Q P Feng, X Zhao, L Edvinsson, T Hedner. Cardiovascular and renal effects of alpha-trinositol in ischemic heart failure rats.
Life sciences.
1995; 57(12):1197-211. doi:
10.1016/0024-3205(95)02066-r. [PMID: 7674809] - W Q Wang, X D Wang, A Gustafson. Reverse cholesterol transport in the rat: influence of short-term D-myo-inositol-1,2,6 trisphosphate (PP56) infusion.
Pharmacology & toxicology.
1993 Jul; 73(1):49-51. doi:
10.1111/j.1600-0773.1993.tb01957.x. [PMID: 8234193] - J H Schwieler, P Hjemdahl. D-myo-inositol-1,2,6-triphosphate (PP56) antagonizes nonadrenergic sympathetic vasoconstriction: possible involvement of neuropeptide Y.
Journal of cardiovascular pharmacology.
1993 Mar; 21(3):347-52. doi:
10.1097/00005344-199303000-00001. [PMID: 7681493] - J Pernow, A Modin, J M Lundberg. No effect of D-myo-inositol-1,2,6-triphosphate on vasoconstriction evoked by neuropeptide Y and non-adrenergic sympathetic nerve stimulation.
European journal of pharmacology.
1992 Nov; 222(1):171-4. doi:
10.1016/0014-2999(92)90836-s. [PMID: 1468494] - E K Potter, L Edvinsson, T Gustafsson. Antagonism of pre- and postjunctional responses to neuropeptide Y and sympathetic stimulation by D-myo-inositol-1,2,6-trisphosphate in the anaesthetised dog.
European journal of pharmacology.
1992 Oct; 221(2-3):307-14. doi:
10.1016/0014-2999(92)90717-i. [PMID: 1426007] - J C Ruf, M Ciavatti, T Gustafsson, S Renaud. Effect of D-myo-inositol on platelet function and composition and on cataract development in streptozotocin-induced diabetic rats.
Biochemical medicine and metabolic biology.
1992 Aug; 48(1):46-55. doi:
10.1016/0885-4505(92)90047-3. [PMID: 1388035] - B Ahrén. Inhibitory effect of D-myo-inositol-1,2,6-trisphosphate on glucose-stimulated insulin secretion in the mouse.
Neuropeptides.
1992 Mar; 21(3):163-6. doi:
10.1016/0143-4179(92)90040-4. [PMID: 1630602] - J C Ruf, M Ciavatti, T Gustafsson, S Renaud. Effects of PP-56 and vitamin E on platelet hyperaggregability, fatty acid abnormalities, and clinical manifestations in streptozocin-induced diabetic rats.
Diabetes.
1991 Feb; 40(2):233-9. doi:
10.2337/diab.40.2.233. [PMID: 1825073] - A Claxson, C Morris, D Blake, M Sirén, B Halliwell, T Gustafsson, B Löfkvist, I Bergelin. The anti-inflammatory effects of D-myo-inositol-1.2.6-trisphosphate (PP56) on animal models of inflammation.
Agents and actions.
1990 Jan; 29(1-2):68-70. doi:
10.1007/bf01964724. [PMID: 2327318] - R P Wilson, P L Fowlkes. Activity of glutamine synthetase in channel catfish tissues determined by an improved tissue assay method.
Comparative biochemistry and physiology. B, Comparative biochemistry.
1976; 54(3):365-8. doi:
10.1016/0305-0491(76)90258-3. [PMID: 6197]