Oxalate (BioDeep_00000840409)
代谢物信息卡片
化学式: C2O4-2 (87.97966)
中文名称:
谱图信息:
最多检出来源 Homo sapiens(blood) 10.71%
分子结构信息
SMILES: C(=O)(C(=O)[O-])[O-]
InChI: InChI=1S/C2H2O4/c3-1(4)2(5)6/h(H,3,4)(H,5,6)/p-2
相关代谢途径
Reactome(3)
BioCyc(28)
- anaerobic energy metabolism (invertebrates, mitochondrial)
- superpathway of anaerobic energy metabolism (invertebrates)
- superpathway of N-acetylneuraminate degradation
- superpathway of hexitol degradation (bacteria)
- superpathway of anaerobic sucrose degradation
- superpathway of glycol metabolism and degradation
- superpathway of cytosolic glycolysis (plants), pyruvate dehydrogenase and TCA cycle
- glycolate and glyoxylate degradation II
- glycolysis IV (plant cytosol)
- superpathway of pentose and pentitol degradation
- superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass
- superpathway of glyoxylate bypass and TCA
- superpathway of glycolysis and the Entner-Doudoroff pathway
- gluconeogenesis I
- glycolysis II (from fructose 6-phosphate)
- glycolysis I (from glucose 6-phosphate)
- crotonyl-CoA/ethylmalonyl-CoA/hydroxybutyryl-CoA cycle (engineered)
- TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)
- oxalate biosynthesis
- orcinol degradation
- 4-hydroxyphenylacetate degradation
- 3-phenylpropanoate and 3-(3-hydroxyphenyl)propanoate degradation
- 2-hydroxypenta-2,4-dienoate degradation
- oxalate degradation V
- oxalate degradation IV
- pyruvate fermentation to lactate
- D-lactate to cytochrome bo oxidase electron transfer
- L-ascorbate degradation III
PlantCyc(5)
代谢反应
37 个相关的代谢反应过程信息。
Reactome(4)
- Metabolism:
3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-one-CoA + CoA-SH ⟶ choloyl-CoA + propionyl CoA
- Metabolism of vitamins and cofactors:
H2O + Oxygen + PXL ⟶ H2O2 + PDXate
- Metabolism of water-soluble vitamins and cofactors:
H2O + Oxygen + PXL ⟶ H2O2 + PDXate
- Vitamin C (ascorbate) metabolism:
DHA + H2O + H2O2 ⟶ oxalate + threonate
BioCyc(7)
- trichloroethene degradation:
O2 + trichloroethanol ⟶ 2,2,2-trichloroacetate + H+ + H2O
- oxalate biosynthesis:
H2O + oxaloacetate ⟶ H+ + acetate + oxalate
- oxalate degradation V:
H+ + oxalate ⟶ CO2 + formate
- oxalate degradation IV:
H+ + O2 + oxalate ⟶ CO2 + hydrogen peroxide
- oxalate degradation V:
H+ + oxalate ⟶ CO2 + formate
- factor 420 biosynthesis:
4-hydroxyphenylpyruvate + ARP + H2O + SAM ⟶ 5'-deoxyadenosine + 7,8-didemethyl-8-hydroxy-5-deazariboflavin + H+ + ammonium + met + oxalate
- factor 420 biosynthesis:
4-hydroxyphenylpyruvate + ARP + H2O + SAM ⟶ 5'-deoxyadenosine + 7,8-didemethyl-8-hydroxy-5-deazariboflavin + H+ + ammonium + met + oxalate
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(26)
- trichloroethene degradation:
2,2,2-trichloroacetate + NADPH + O2 ⟶ H+ + NADP+ + chloride + oxalate
- trichloroethene degradation:
O2 + trichloroethene ⟶ 2,2,2-trichloroacetate + H+
- trichloroethene degradation:
2,2,2-trichloroacetate + NADPH + O2 ⟶ H+ + NADP+ + chloride + oxalate
- oxalate biosynthesis:
H2O + oxaloacetate ⟶ H+ + acetate + oxalate
- oxalate biosynthesis:
H2O + oxaloacetate ⟶ H+ + acetate + oxalate
- oxalate biosynthesis:
H2O + oxaloacetate ⟶ H+ + acetate + oxalate
- oxalate biosynthesis:
H2O + oxaloacetate ⟶ H+ + acetate + oxalate
- oxalate biosynthesis:
H2O + oxaloacetate ⟶ H+ + acetate + oxalate
- oxalate biosynthesis:
H2O + oxaloacetate ⟶ H+ + acetate + oxalate
- oxalate biosynthesis:
H2O + oxaloacetate ⟶ H+ + acetate + oxalate
- oxalate biosynthesis:
H2O + oxaloacetate ⟶ H+ + acetate + oxalate
- oxalate biosynthesis:
H2O + oxaloacetate ⟶ H+ + acetate + oxalate
- oxalate degradation IV:
H+ + O2 + oxalate ⟶ CO2 + hydrogen peroxide
- oxalate degradation IV:
H+ + O2 + oxalate ⟶ CO2 + hydrogen peroxide
- oxalate degradation IV:
H+ + O2 + oxalate ⟶ CO2 + hydrogen peroxide
- oxalate degradation IV:
H+ + O2 + oxalate ⟶ CO2 + hydrogen peroxide
- oxalate degradation IV:
H+ + O2 + oxalate ⟶ CO2 + hydrogen peroxide
- oxalate degradation IV:
H+ + O2 + oxalate ⟶ CO2 + hydrogen peroxide
- oxalate degradation IV:
H+ + O2 + oxalate ⟶ CO2 + hydrogen peroxide
- oxalate degradation IV:
H+ + O2 + oxalate ⟶ CO2 + hydrogen peroxide
- oxalate degradation IV:
H+ + O2 + oxalate ⟶ CO2 + hydrogen peroxide
- oxalate degradation IV:
H+ + O2 + oxalate ⟶ CO2 + hydrogen peroxide
- oxalate degradation IV:
H+ + O2 + oxalate ⟶ CO2 + hydrogen peroxide
- oxalate degradation IV:
H+ + O2 + oxalate ⟶ CO2 + hydrogen peroxide
- oxalate degradation IV:
H+ + O2 + oxalate ⟶ CO2 + hydrogen peroxide
- oxalate degradation IV:
H+ + O2 + oxalate ⟶ CO2 + hydrogen peroxide
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Marcin Grąz. Role of oxalic acid in fungal and bacterial metabolism and its biotechnological potential.
World journal of microbiology & biotechnology.
2024 Apr; 40(6):178. doi:
10.1007/s11274-024-03973-5
. [PMID: 38662173] - Peter Capek, Iveta Uhliariková. Antioxidant Active Polysaccharides Extracted with Oxalate from Wild Blackthorn Fruits (Prunus spinosa L.).
International journal of molecular sciences.
2024 Apr; 25(8):. doi:
10.3390/ijms25084519
. [PMID: 38674109] - Hend A Essa, Alaa M Ali, Mona A Saied. Cymbopogon proximus and Petroselinum crispum seed ethanolic extract/Gum Arabic nanogel emulsion: Preventing ethylene glycol and ammonium chloride-induced urolithiasis in rats.
Urolithiasis.
2024 Apr; 52(1):52. doi:
10.1007/s00240-024-01559-2
. [PMID: 38564033] - Yeshan Zhang, Xue Han, Jun Zhao, Menglan Gan, Yaya Chen, Jinxia Zhang, Yu He, Mingkai Wu, Hai Liu. Process optimization and character evaluation of Bletilla striata polysaccharide (BSP) and chitosan (CS) composite hemostatic sponge (BSP-CS).
Biointerphases.
2024 Mar; 19(2):. doi:
10.1116/6.0003369
. [PMID: 38526056] - Jiaxin Chen, Lu Tang, Weileng Guo, Dan Wang, Yugang Sun, Changhong Guo. Oxalic acid secretion alleviates saline-alkali stress in alfalfa by improving photosynthetic characteristics and antioxidant activity.
Plant physiology and biochemistry : PPB.
2024 Mar; 208(?):108475. doi:
10.1016/j.plaphy.2024.108475
. [PMID: 38430786] - Ni Ji, Zhiyuan Liu, Hongbing She, Zhaosheng Xu, Helong Zhang, Zhengwu Fang, Wei Qian. A Genome-Wide Association Study Reveals the Genetic Mechanisms of Nutrient Accumulation in Spinach.
Genes.
2024 Jan; 15(2):. doi:
10.3390/genes15020172
. [PMID: 38397162] - Ninghui Cheng, Paul A Nakata. Disruption of the Arabidopsis Acyl-Activating Enzyme 3 Impairs Seed Coat Mucilage Accumulation and Seed Germination.
International journal of molecular sciences.
2024 Jan; 25(2):. doi:
10.3390/ijms25021149
. [PMID: 38256222] - Juan Agustín García, Gina Rustichelli Millán, Valeria Scioli, Gastón Britos, Eleonora Morrell, Ernesto Odriozola, Juan Francisco Micheloud, Germán Cantón. Amaranthus hybridus (syn. quitensis) intoxication in cattle in Argentina: Case report.
Toxicon : official journal of the International Society on Toxinology.
2024 Jan; 237(?):107533. doi:
10.1016/j.toxicon.2023.107533
. [PMID: 38013055] - Natalia Stepanova, Ganna Tolstanova, Iryna Aleksandrova, Lesya Korol, Taisa Dovbynchuk, Victoria Driianska, Svitlana Savchenko. Gut Microbiota's Oxalate-Degrading Activity and Its Implications on Cardiovascular Health in Patients with Kidney Failure: A Pilot Prospective Study.
Medicina (Kaunas, Lithuania).
2023 Dec; 59(12):. doi:
10.3390/medicina59122189
. [PMID: 38138292] - Maria Manzoor, Muhammad Shafiq, Iram Gul, Usman Rauf Kamboh, Dong-Xing Guan, Abdulrahman Ali Alazba, Sven Tomforde, Muhammad Arshad. Enhanced lead phytoextraction and soil health restoration through exogenous supply of organic ligands: Geochemical modeling".
Journal of environmental management.
2023 Dec; 348(?):119435. doi:
10.1016/j.jenvman.2023.119435
. [PMID: 37890401] - Tianhui Yuan, Yuqi Xia, Shengyu Pan, Bojun Li, Zehua Ye, Xinzhou Yan, Weimin Hu, Lei Li, Baofeng Song, Weimin Yu, Haoyong Li, Ting Rao, Fangyou Lin, Xiangjun Zhou, Fan Cheng. STAT6 promoting oxalate crystal deposition-induced renal fibrosis by mediating macrophage-to-myofibroblast transition via inhibiting fatty acid oxidation.
Inflammation research : official journal of the European Histamine Research Society ... [et al.].
2023 Nov; ?(?):. doi:
10.1007/s00011-023-01803-2
. [PMID: 37924395] - Sara Zayed, David S Goldfarb, Shivam Joshi. Popular Diets and Kidney Stones.
Advances in kidney disease and health.
2023 Nov; 30(6):529-536. doi:
10.1053/j.akdh.2023.10.002
. [PMID: 38453270] - Parveen Kumar, Emma Laurence, David K Crossman, Dean G Assimos, Michael P Murphy, Tanecia Mitchell. Oxalate disrupts monocyte and macrophage cellular function via Interleukin-10 and mitochondrial reactive oxygen species (ROS) signaling.
Redox biology.
2023 11; 67(?):102919. doi:
10.1016/j.redox.2023.102919
. [PMID: 37806112] - Max Klotzsche, Manja Vogel, Susanne Sachs, Johannes Raff, Thorsten Stumpf, Björn Drobot, Robin Steudtner. How tobacco (Nicotiana tabacum) BY-2 cells cope with Eu(III) - a microspectroscopic study.
The Analyst.
2023 Sep; 148(19):4668-4676. doi:
10.1039/d3an00741c
. [PMID: 37646162] - Zehua Ye, Yuqi Xia, Lei Li, Bojun Li, Lijia Chen, Weimin Yu, Yuan Ruan, Ting Rao, Xiangjun Zhou, Fan Cheng. p53 deacetylation alleviates calcium oxalate deposition-induced renal fibrosis by inhibiting ferroptosis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2023 Aug; 164(?):114925. doi:
10.1016/j.biopha.2023.114925
. [PMID: 37236026] - Mónica Yorlady Alzate Zuluaga, André Luiz Martinez de Oliveira, Fabio Valentinuzzi, Nádia Souza Jayme, Sonia Monterisi, Roberto Fattorini, Stefano Cesco, Youry Pii. An insight into the role of the organic acids produced by Enterobacter sp. strain 15S in solubilizing tricalcium phosphate: in situ study on cucumber.
BMC microbiology.
2023 Jul; 23(1):184. doi:
10.1186/s12866-023-02918-6
. [PMID: 37438698] - Paola Aparecida Raeski, Gustavo Heiden, Andressa Novatski, Vijayasankar Raman, Ikhlas Ahmed Khan, Jane Manfron. Calcium oxalate crystal macropattern and its usefulness in the taxonomy of Baccharis (Asteraceae).
Microscopy research and technique.
2023 Jul; 86(7):862-881. doi:
10.1002/jemt.24363
. [PMID: 37248646] - Haiyan Yang, Liping Qi, Jinrong Zhou, Qian Li, Xin Yuan, Mei Zhang, Yong He, Ke Huang, Piaopiao Chen. Metal ions-regulated chemical vapor generation of Hg2+:mechanism and application in miniaturized point discharge atomic emission spectrometry assay of oxalate in clinical urolithiasis samples.
Analytica chimica acta.
2023 Jun; 1262(?):341223. doi:
10.1016/j.aca.2023.341223
. [PMID: 37179054] - Prabhatchandra Dube, Vaishnavi Aradhyula, Apurva Lad, Fatimah K Khalaf, Joshua D Breidenbach, Eshita Kashaboina, Snigdha Gorthi, Shangari Varatharajan, Travis W Stevens, Jacob A Connolly, Sophia M Soehnlen, Ambika Sood, Amulya Marellapudi, Meghana Ranabothu, Andrew L Kleinhenz, Oliver Domenig, Lance D Dworkin, Deepak Malhotra, Steven T Haller, David J Kennedy. Novel Model of Oxalate Diet-Induced Chronic Kidney Disease in Dahl-Salt-Sensitive Rats.
International journal of molecular sciences.
2023 Jun; 24(12):. doi:
10.3390/ijms241210062
. [PMID: 37373209] - Garrett N Ungerer, Christine W Liaw, Aaron M Potretzke, David J Sas, Patricio C Gargollo, Candace F Granberg, Kevin Koo. Examination of nutritional factors associated with urolithiasis risk in plant based meat alternatives marketed to children and infants.
Journal of pediatric urology.
2023 Apr; ?(?):. doi:
10.1016/j.jpurol.2023.04.017
. [PMID: 37150637] - Bryan Misiewicz, Donald Mencer, William Terzaghi, Adam L VanWert. Analytical Methods for Oxalate Quantification: The Ubiquitous Organic Anion.
Molecules (Basel, Switzerland).
2023 Apr; 28(7):. doi:
10.3390/molecules28073206
. [PMID: 37049969] - Caitao Dong, Chao Song, Ziqi He, Qianlin Song, Tianbao Song, Junwei Liu, Yunhe Xiong, Xiaozhe Su, Jiawei Zhou, Sixing Yang, Wenbiao Liao. Protective efficacy of Schizandrin B on ameliorating nephrolithiasis via regulating GSK3β/Nrf2 signaling-mediated ferroptosis in vivo and in vitro.
International immunopharmacology.
2023 Apr; 117(?):110042. doi:
10.1016/j.intimp.2023.110042
. [PMID: 36940552] - M A Abdelaziz, O M Ahmed, M Abdel-Gabbar, M R Mohammad, S R Ibrahim, M H Abdelzaher, A P Mohideen, S A Moawd, A I Geddawy. The preventive effects of Ulva lactuca aqueous extract, ulvan polysaccharides and atorvastatin on ethylene glycol-induced hyperoxaluria.
European review for medical and pharmacological sciences.
2023 Apr; 27(8):3699-3713. doi:
10.26355/eurrev_202304_32169
. [PMID: 37140319] - Rasim Güzel, İsmet Bilger Erïhan, İsa Özaydin, Uğur Aydin, Murat Bağcioğlu, Ramazan Kocaaslan, Ümit Yildirim, Kemal Sarica. Dose-dependant preventive effect of a herbal compound on crystal formation in rat model.
Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica.
2023 03; 95(1):11114. doi:
10.4081/aiua.2023.11114
. [PMID: 36971199] - Shuai Yuan, Ibrahim Abdel Aziz Ibrahim, Ruimin Ren. Anti-urolithiatic Activity of Daidzin in Ethylene Glycol-Induced Urolithiasis in Rats.
Applied biochemistry and biotechnology.
2023 Feb; 195(2):905-918. doi:
10.1007/s12010-022-04124-y
. [PMID: 36227501] - Christine W Liaw, Aaron M Potretzke, Jared S Winoker, Brian R Matlaga, John C Lieske, Kevin Koo. Dietary Assessment of Lithogenic Factors in Plant-Based Meat Products.
Journal of endourology.
2023 01; 37(1):119-122. doi:
10.1089/end.2022.0189
. [PMID: 36103379] - Ninghui Cheng, Vincent Paris, Xiaolan Rao, Xiaoqiang Wang, Paul A Nakata. A conserved oxalyl-coenzyme A decarboxylase in oxalate catabolism.
Plant signaling & behavior.
2022 12; 17(1):2062555. doi:
10.1080/15592324.2022.2062555
. [PMID: 35510715] - Y Wang, H M Zhang, X R Deng, W W Liu, L Chen, N Zhao, X H Zhang, Z B Song, Y Geng, L L Ji, Y Wang, Z L Zhang. [Diagnostic values of urinary citrate for kidney stones in patients with primary gout].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences.
2022 Dec; 54(6):1134-1140. doi:
"
. [PMID: 36533345] - Zongming Yang, Pingjuan Zhao, Wentao Peng, Zifan Liu, Guishui Xie, Xiaowei Ma, Zewei An, Feng An. Cloning, Expression Analysis, and Functional Characterization of Candidate Oxalate Transporter Genes of HbOT1 and HbOT2 from Rubber Tree (Hevea brasiliensis).
Cells.
2022 Nov; 11(23):. doi:
10.3390/cells11233793
. [PMID: 36497054] - Liangfeng Liu, Huai Chen, Yixin He, Jianliang Liu, Xue Dan, Lin Jiang, Wei Zhan. Carbon stock stability in drained peatland after simulated plant carbon addition: Strong dependence on deeper soil.
The Science of the total environment.
2022 Nov; 848(?):157539. doi:
10.1016/j.scitotenv.2022.157539
. [PMID: 35908690] - Atsuko Miyagi, Kazuhisa Mori, Toshiki Ishikawa, Satoshi Ohkubo, Shunsuke Adachi, Masatoshi Yamaguchi, Taiichiro Ookawa, Toshihisa Kotake, Maki Kawai-Yamada. Metabolomic analysis of rice brittle culm mutants reveals each mutant- specific metabolic pattern in each organ.
Metabolomics : Official journal of the Metabolomic Society.
2022 11; 18(12):95. doi:
10.1007/s11306-022-01958-9
. [PMID: 36409428] - Kashif Tanwir, Muhammad Shahid, Saghir Abbas, Qasim Ali, Muhammad Sohail Akram, Hassan Javed Chaudhary, Muhammad Tariq Javed. Deciphering distinct root exudation, ionomics, and physio-biochemical attributes of Serratia marcescens CP-13 inoculated differentially Cd tolerant Zea mays cultivars.
Environmental science and pollution research international.
2022 Oct; 29(47):71632-71649. doi:
10.1007/s11356-022-20945-0
. [PMID: 35599287] - Nobuya Shirai. Organic Acid Analysis in Green Tea Leaves Using High-performance Liquid Chromatography.
Journal of oleo science.
2022 Sep; 71(9):1413-1419. doi:
10.5650/jos.ess22135
. [PMID: 35965093] - Margaret L Doolin, Sara B Weinstein, M Denise Dearing. PINWORMS ARE ASSOCIATED WITH TAXONOMIC BUT NOT FUNCTIONAL DIFFERENCES IN THE GUT MICROBIOME OF WHITE-THROATED WOODRATS (NEOTOMA ALBIGULA).
The Journal of parasitology.
2022 09; 108(5):408-418. doi:
10.1645/22-11
. [PMID: 36066907] - Maxime Gautreau, Sylvie Durand, Angeline Paturel, Sophie Le Gall, Loic Foucat, Xavier Falourd, Bruno Novales, Marie-Christine Ralet, Sylvie Chevallier, Antoine Kervoelen, Alain Bourmaud, Fabienne Guillon, Johnny Beaugrand. Impact of cell wall non-cellulosic and cellulosic polymers on the mechanical properties of flax fibre bundles.
Carbohydrate polymers.
2022 Sep; 291(?):119599. doi:
10.1016/j.carbpol.2022.119599
. [PMID: 35698346] - Parveen Kumar, Zhengqin Yang, Jeremie M Lever, Miranda D Chávez, Huma Fatima, David K Crossman, Craig L Maynard, James F George, Tanecia Mitchell. Hydroxyproline stimulates inflammation and reprograms macrophage signaling in a rat kidney stone model.
Biochimica et biophysica acta. Molecular basis of disease.
2022 09; 1868(9):166442. doi:
10.1016/j.bbadis.2022.166442
. [PMID: 35562038] - Chi Yuan, Xi Jin, Yushi He, Yu Liu, Liyuan Xiang, Kunjie Wang. Association of dietary patterns with gut microbiota in kidney stone and non-kidney stone individuals.
Urolithiasis.
2022 Aug; 50(4):389-399. doi:
10.1007/s00240-022-01325-2
. [PMID: 35460343] - Dongun Lee, Peter Chang-Whan Lee, Jeong Hee Hong, Dong Min Shin. Estrogen treatment reduced oxalate transporting activity and enhanced migration through the involvement of SLC26A6 in lung cancer cells.
Toxicology in vitro : an international journal published in association with BIBRA.
2022 Aug; 82(?):105373. doi:
10.1016/j.tiv.2022.105373
. [PMID: 35500753] - Hsin-Hsiao Scott Wang, John Panagides, Dylan Cahill, Clement Bottino, Erinn T Rhodes, Eric Fleegler, Bartley G Cilento, Michael P Kurtz, Michelle Baum, Caleb P Nelson. Dietary Risk Factors for Pediatric Kidney Stones: A Case-Control Study.
The Journal of urology.
2022 08; 208(2):434-440. doi:
10.1097/ju.0000000000002687
. [PMID: 35377774] - Jinna Xie, Zehua Ye, Lei Li, Yuqi Xia, Run Yuan, Yuan Ruan, Xiangjun Zhou. Ferrostatin‑1 alleviates oxalate‑induced renal tubular epithelial cell injury, fibrosis and calcium oxalate stone formation by inhibiting ferroptosis.
Molecular medicine reports.
2022 08; 26(2):. doi:
10.3892/mmr.2022.12772
. [PMID: 35703358] - Onur Cil, Tifany Chu, Sujin Lee, Peter M Haggie, Alan S Verkman. Small-molecule inhibitor of intestinal anion exchanger SLC26A3 for treatment of hyperoxaluria and nephrolithiasis.
JCI insight.
2022 07; 7(13):. doi:
10.1172/jci.insight.153359
. [PMID: 35608921] - Joshua Chambers, Alice Appleton, Christopher Dudley. Pancreatic insufficiency as a complication of type 1 diabetes causing enteric hyperoxaluria in a transplant kidney.
BMJ case reports.
2022 Jul; 15(7):. doi:
10.1136/bcr-2021-248162
. [PMID: 35787489] - Pegah Dejban, John C Lieske. New therapeutics for primary hyperoxaluria type 1.
Current opinion in nephrology and hypertension.
2022 07; 31(4):344-350. doi:
10.1097/mnh.0000000000000790
. [PMID: 35266883] - Yoshinari Oka, Masashi Miyazaki, Shigeko Takatsu, Hiroaki Matsuda. Calcium-Based Phosphate Binders and Plasma Oxalate Concentration in Dialysis Patients.
Journal of the American Society of Nephrology : JASN.
2022 Jul; 33(7):1427. doi:
10.1681/asn.2022030248
. [PMID: 35500940] - Anda Mihaela Naciu, Gaia Tabacco, John P Bilezikian, Assunta Santonati, Daniela Bosco, Giosuè Giordano Incognito, Gianluigi Gaspa, Silvia Manfrini, Alberto Falchetti, Pierpaolo Trimboli, Gherardo Mazziotti, Nicola Napoli, Gianfranco Sanson, Roberto Cesareo, Fabio Vescini, Andrea Palermo. Calcium Citrate Versus Calcium Carbonate in the Management of Chronic Hypoparathyroidism: A Randomized, Double-Blind, Crossover Clinical Trial.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
2022 07; 37(7):1251-1259. doi:
10.1002/jbmr.4564
. [PMID: 35466449] - Shuzhe Wang, Yan Wang, Bohua Xu, Tian Qin, Yupeng Lv, Heng Yan, Yifei Shao, Yangyang Fang, Shaoqiu Zheng, Yunliang Qiu. Biodistribution of 89Zr-oxine-labeled human bone marrow-derived mesenchymal stem cells by micro-PET/computed tomography imaging in Sprague-Dawley rats.
Nuclear medicine communications.
2022 Jul; 43(7):834-846. doi:
10.1097/mnm.0000000000001562
. [PMID: 35438673] - Alejandro Felipe González, Carlos R Núñez Cairo, Yamilet I Gutiérrez Gaitén, Ramón Scull Lizama, Melvis C Zumata Dubé, Evelin Iglesia Docinas, Noemí Pazo Bou, Kenn Foubert, Luc Pieters, René Delgado Hernández. Phytochemical characterisation and in vivo antilithiatic activity of the stems of Caesalpinia bahamensis (Brasilete).
Natural product research.
2022 Jul; 36(14):3765-3769. doi:
10.1080/14786419.2021.1883605
. [PMID: 33550871] - Anja Pfau, Felix Knauf. Authors' Reply: Calcium-Based Phosphate Binders and Plasma Oxalate Concentration in Dialysis Patients.
Journal of the American Society of Nephrology : JASN.
2022 Jul; 33(7):1428. doi:
10.1681/asn.2022030359
. [PMID: 35500939] - Natalia Stepanova, Iryna Akulenko, Tetyana Serhiichuk, Taisa Dovbynchuk, Svitlana Savchenko, Ganna Tolstanova. Synbiotic supplementation and oxalate homeostasis in rats: focus on microbiota oxalate-degrading activity.
Urolithiasis.
2022 Jun; 50(3):249-258. doi:
10.1007/s00240-022-01312-7
. [PMID: 35129638] - De-Han Cai, Xiao-Lin Fang. Portulaca Oleracea-associated oxalate nephropathy complicated with an ANCA-positive acute renal injury: A case report.
Transplant immunology.
2022 06; 72(?):101589. doi:
10.1016/j.trim.2022.101589
. [PMID: 35346825] - Anubha Singh, Simran Tandon, Dhruv Kumar, Tanzeer Kaur, Kavindra Kumar Kesari, Chanderdeep Tandon. Insights into the cytoprotective potential of Bergenia ligulata against oxalate-induced oxidative stress and epithelial-mesenchymal transition (EMT) via TGFβ1/p38MAPK pathway in human renal epithelial cells.
Urolithiasis.
2022 Jun; 50(3):259-278. doi:
10.1007/s00240-022-01315-4
. [PMID: 35174397] - Jonathan G Pavlinec, Mark Martin, William Donelan, Elizabeth Kwenda, Paul Dominguez-Gutierrez, Vincent G Bird, Benjamin K Canales. Initial experience: ex-vivo perfused pig kidney to study urinary oxalate excretion.
Urolithiasis.
2022 Jun; 50(3):239-247. doi:
10.1007/s00240-022-01322-5
. [PMID: 35294609] - Ruiying Shi, Lichen Liang, Weitao Liu, Aurang Zeb. Kochia scoparia L., a newfound candidate halophyte, for phytoremediation of cadmium-contaminated saline soils.
Environmental science and pollution research international.
2022 Jun; 29(29):44759-44768. doi:
10.1007/s11356-022-18895-8
. [PMID: 35138541] - Thomas A Forbes, Bob D Brown, Chengjung Lai. Therapeutic RNA interference: A novel approach to the treatment of primary hyperoxaluria.
British journal of clinical pharmacology.
2022 06; 88(6):2525-2538. doi:
10.1111/bcp.14925
. [PMID: 34022071] - Xinyuan Cui, Xiaojun Chen, Yifu Li, Xiao Fu, Pan'ai Song, Li Xiao, Lin Sun, Hong Liu, Xuejing Zhu, Shuguang Yuan. Oxalate crystal-related acute renal injury caused by orlistat: A case report.
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences.
2022 May; 47(5):583-587. doi:
10.11817/j.issn.1672-7347.2022.210393
. [PMID: 35753728] - Nathalie Demoulin, Selda Aydin, Valentine Gillion, Johann Morelle, Michel Jadoul. Pathophysiology and Management of Hyperoxaluria and Oxalate Nephropathy: A Review.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2022 05; 79(5):717-727. doi:
10.1053/j.ajkd.2021.07.018
. [PMID: 34508834] - Anam Tariq, Jingsha Chen, Bing Yu, Eric Boerwinkle, Josef Coresh, Morgan E Grams, Casey M Rebholz. Metabolomics of Dietary Acid Load and Incident Chronic Kidney Disease.
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation.
2022 05; 32(3):292-300. doi:
10.1053/j.jrn.2021.05.005
. [PMID: 34294549] - Jiangshu He, Jin Yang, Lin Chen, Pinglin He, Xun Liu, Kai Wang, Taotao Dong, Jia Li, Xudong Ma, Amend Bastian, Stenzl Arnulf. Serum/glucocorticoid-regulated kinase 1-targeted transient receptor potential oxalate subtype 1 regulates bladder smooth muscle cell proliferation due to bladder outlet obstruction in mice via activated T cell nuclear factor transcription factor 2.
IUBMB life.
2022 05; 74(5):463-473. doi:
10.1002/iub.2605
. [PMID: 35148462] - James F Borin, John Knight, Ross P Holmes, Shivam Joshi, David S Goldfarb, Stacy Loeb. Plant-Based Milk Alternatives and Risk Factors for Kidney Stones and Chronic Kidney Disease.
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation.
2022 05; 32(3):363-365. doi:
10.1053/j.jrn.2021.03.011
. [PMID: 34045136] - Yitong Yin, Ximing Luo, Xiangyu Guan, Jiawei Zhao, Yuan Tan, Xiaonan Shi, Mingtao Luo, Xiangcai Han. Arsenic Release from Soil Induced by Microorganisms and Environmental Factors.
International journal of environmental research and public health.
2022 04; 19(8):. doi:
10.3390/ijerph19084512
. [PMID: 35457378] - A Verhulst, B Dehmel, E Lindner, M E Akerman, P C D'Haese. Oxalobacter formigenes treatment confers protective effects in a rat model of primary hyperoxaluria by preventing renal calcium oxalate deposition.
Urolithiasis.
2022 Apr; 50(2):119-130. doi:
10.1007/s00240-022-01310-9
. [PMID: 35122487] - Marie-Noëlle Méaux, Anne-Laure Sellier-Leclerc, Cécile Acquaviva-Bourdain, Jérôme Harambat, Lise Allard, Justine Bacchetta. The effect of lumasiran therapy for primary hyperoxaluria type 1 in small infants.
Pediatric nephrology (Berlin, Germany).
2022 04; 37(4):907-911. doi:
10.1007/s00467-021-05393-1
. [PMID: 35015123] - Louise Stone. Microbiota manipulation to prevent oxalate kidney stone formation.
Nature reviews. Urology.
2022 04; 19(4):193. doi:
10.1038/s41585-022-00585-2
. [PMID: 35296831] - Andrew Maike, Daniel Sturgill, Alex Gallan. Oxalate Nephropathy in a Renal Transplant Recipient After Receiving High Dose Ascorbic Acid.
The American journal of the medical sciences.
2022 04; 363(4):e33-e34. doi:
10.1016/j.amjms.2021.05.025
. [PMID: 34077704] - Hannah Dill, Cristina Martin-Higueras, Bernd Hoppe. Diet-related urine collections: assistance in categorization of hyperoxaluria.
Urolithiasis.
2022 Apr; 50(2):141-148. doi:
10.1007/s00240-021-01290-2
. [PMID: 34821949] - Xiaoyuan Qian, Weisong Wu, Henglong Hu, Xiao Yu, Shaogang Wang, Jianning Zhu, Jiaqiao Zhang. The role of reactive oxygen species derived from different NADPH oxidase isoforms and mitochondria in oxalate-induced oxidative stress and cell injury.
Urolithiasis.
2022 Apr; 50(2):149-158. doi:
10.1007/s00240-022-01309-2
. [PMID: 35128564] - Zahra Bahadoran, Parvin Mirmiran, Fereidoun Azizi. Dietary oxalate to calcium ratio and incident cardiovascular events: a 10-year follow-up among an Asian population.
Nutrition journal.
2022 03; 21(1):21. doi:
10.1186/s12937-022-00773-1
. [PMID: 35346210] - Ohyun Kwon, Yaerim Kim, Jin Hyuk Paek, Woo Yeong Park, Seungyeup Han, Hyungchan Sin, Kyubok Jin. Chaga mushroom-induced oxalate nephropathy that clinically manifested as nephrotic syndrome: A case report.
Medicine.
2022 Mar; 101(10):e28997. doi:
10.1097/md.0000000000028997
. [PMID: 35451393] - Han-Na Kim, Jae Heon Kim, Yoosoo Chang, Dongmin Yang, Kwan Joong Joo, Young-Sam Cho, Heung Jae Park, Hyung-Lae Kim, Seungho Ryu. Gut microbiota and the prevalence and incidence of renal stones.
Scientific reports.
2022 03; 12(1):3732. doi:
10.1038/s41598-022-07796-y
. [PMID: 35260689] - David Lubkowicz, Nicholas G Horvath, Michael J James, Pasquale Cantarella, Lauren Renaud, Christopher G Bergeron, Ron B Shmueli, Cami Anderson, Jian-Rong Gao, Caroline B Kurtz, Mylene Perreault, Mark R Charbonneau, Vincent M Isabella, David L Hava. An engineered bacterial therapeutic lowers urinary oxalate in preclinical models and in silico simulations of enteric hyperoxaluria.
Molecular systems biology.
2022 03; 18(3):e10539. doi:
10.15252/msb.202110539
. [PMID: 35253995] - Kevin Shee, Marshall L Stoller. Perspectives in primary hyperoxaluria - historical, current and future clinical interventions.
Nature reviews. Urology.
2022 Mar; 19(3):137-146. doi:
10.1038/s41585-021-00543-4
. [PMID: 34880452] - Natalia Stepanova, Lesya Korol, Larysa Lebid, Lyudmyla Snisar, Svitlana Savchenko. Oxalate Balance in Peritoneal Dialysis Patients: A Potential Role of Dialysis-related Peritonitis.
In vivo (Athens, Greece).
2022 Mar; 36(2):925-933. doi:
10.21873/invivo.12782
. [PMID: 35241551] - Erik Carlson, Kristen Stewart, Kathleen Baier, Linda McGuigan, Tobi Culpepper, William Powell. Pathogen-induced expression of a blight tolerance transgene in American chestnut.
Molecular plant pathology.
2022 03; 23(3):370-382. doi:
10.1111/mpp.13165
. [PMID: 34841616] - Bernd Hoppe, Annelize Koch, Pierre Cochat, Sander F Garrelfs, Michelle A Baum, Jaap W Groothoff, Graham Lipkin, Martin Coenen, Gesa Schalk, Aniruddha Amrite, David McDougall, Kelly Barrios, Craig B Langman. Safety, pharmacodynamics, and exposure-response modeling results from a first-in-human phase 1 study of nedosiran (PHYOX1) in primary hyperoxaluria.
Kidney international.
2022 03; 101(3):626-634. doi:
10.1016/j.kint.2021.08.015
. [PMID: 34481803] - Virginia L Hood, Kevan M Sternberg, Desiree de Waal, John R Asplin, Carley Mulligan, Peter W Callas. Association of Urine Findings with Metabolic Syndrome Traits in a Population of Patients with Nephrolithiasis.
Kidney360.
2022 02; 3(2):317-324. doi:
10.34067/kid.0002292021
. [PMID: 35373120] - Fang Dong, Shan Jiang, Chun Tang, Xiaohua Wang, Xiaoqiu Ren, Qichun Wei, Jiong Tian, Weipeng Hu, Jie Guo, Xiaodong Fu, Linlin Liu, Andreas Patzak, Pontus B Persson, Fei Gao, En Yin Lai, Liang Zhao. Trimethylamine N-oxide promotes hyperoxaluria-induced calcium oxalate deposition and kidney injury by activating autophagy.
Free radical biology & medicine.
2022 02; 179(?):288-300. doi:
10.1016/j.freeradbiomed.2021.11.010
. [PMID: 34767921] - Seyed Fazel Mirahmadi, Mohammadreza Hassandokht, Reza Fatahi, Mohammad Reza Naghavi, Karamatollah Rezaei. High and low oxalate content in spinach: an investigation of accumulation patterns.
Journal of the science of food and agriculture.
2022 Jan; 102(2):836-843. doi:
10.1002/jsfa.11419
. [PMID: 34233027] - Daniel G Fuster, Gaétan A Morard, Lisa Schneider, Cedric Mattmann, David Lüthi, Bruno Vogt, Nasser A Dhayat. Association of urinary sex steroid hormones with urinary calcium, oxalate and citrate excretion in kidney stone formers.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2022 01; 37(2):335-348. doi:
10.1093/ndt/gfaa360
. [PMID: 33295624] - Iris H Valido, Victor Fuentes-Cebrian, Roberto Boada, Oriol Vallcorba, Montserrat Resina-Gallego, Manuel Valiente, Montserrat López-Mesas. Discriminating the origin of calcium oxalate monohydrate formation in kidney stones via synchrotron microdiffraction.
The Analyst.
2022 Jan; 147(2):349-357. doi:
10.1039/d1an01703a
. [PMID: 34935777] - Veronica Krogstad, Katja Benedikte Prestø Elgstøen, Linda Flaa Johnsen, Anders Hartmann, Lars Mørkrid, Anders Åsberg. High Plasma Oxalate Levels Early After Kidney Transplantation Are Associated With Impaired Long-Term Outcomes.
Transplant international : official journal of the European Society for Organ Transplantation.
2022; 35(?):10240. doi:
10.3389/ti.2022.10240
. [PMID: 35368646] - Zihao Jia, Qiang Zhong, Tao Lin, Turun Song. Subsequent liver transplantation did not reverse recurrence of oxalate nephropathy after isolated kidney transplantation for primary type 2 hyperoxaluria.
Asian journal of surgery.
2022 Jan; 45(1):483-485. doi:
10.1016/j.asjsur.2021.08.066
. [PMID: 34629272] - Prince Singh, Candace F Granberg, Peter C Harris, John C Lieske, Jeffrey H Licht, Andrew Weiss, Dawn S Milliner. Primary Hyperoxaluria Type 3 Can Also Result in Kidney Failure: A Case Report.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2022 01; 79(1):125-128. doi:
10.1053/j.ajkd.2021.05.016
. [PMID: 34245816] - Nizar Joher, Anissa Moktefi, Philippe Grimbert, Eléonore Pagot, Narindra Jouan, Khalil El Karoui, Cécile Maud Champy, Marie Matignon, Thomas Stehlé. Early post-transplant recurrence of oxalate nephropathy in a patient with primary hyperoxaluria type 1, despite pretransplant lumasiran therapy.
Kidney international.
2022 01; 101(1):185-186. doi:
10.1016/j.kint.2021.10.022
. [PMID: 34991805] - Jonathan M Whittamore, Marguerite Hatch. Oxalate Flux Across the Intestine: Contributions from Membrane Transporters.
Comprehensive Physiology.
2021 12; 12(1):2835-2875. doi:
10.1002/cphy.c210013
. [PMID: 34964122] - Roswitha Siener, Albrecht Hesse. Effect of Black Tea Consumption on Urinary Risk Factors for Kidney Stone Formation.
Nutrients.
2021 Dec; 13(12):. doi:
10.3390/nu13124434
. [PMID: 34959987] - Matteo Bargagli, Pietro Manuel Ferraro, Matteo Vittori, Gianmarco Lombardi, Giovanni Gambaro, Bhaskar Somani. Calcium and Vitamin D Supplementation and Their Association with Kidney Stone Disease: A Narrative Review.
Nutrients.
2021 Dec; 13(12):. doi:
10.3390/nu13124363
. [PMID: 34959915] - Matthew R D'Costa, Annamaria T Kausz, Kevin J Carroll, Jóhann P Ingimarsson, Felicity T Enders, Kristin C Mara, Ramila A Mehta, John C Lieske. Subsequent urinary stone events are predicted by the magnitude of urinary oxalate excretion in enteric hyperoxaluria.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2021 12; 36(12):2208-2215. doi:
10.1093/ndt/gfaa281
. [PMID: 33367720] - Ming-Tsang Wu, Chia-Fang Wu, Chia-Chu Liu, Yi-Chun Tsai, Chu-Chih Chen, Yin-Han Wang, Tusty-Jiuan Hsieh. Melamine and oxalate coexposure induces early kidney tubular injury through mitochondrial aberrations and oxidative stress.
Ecotoxicology and environmental safety.
2021 Dec; 225(?):112756. doi:
10.1016/j.ecoenv.2021.112756
. [PMID: 34507040] - Mantu Gupta, Blair Gallante, Jacob N Bamberger, Johnathan A Khusid, Egor Parkhomenko, Ryan Chandhoke, Jillian Capodice, William Atallah. Prospective Randomized Evaluation of Idiopathic Hyperoxaluria Treatments.
Journal of endourology.
2021 12; 35(12):1844-1851. doi:
10.1089/end.2021.0122
. [PMID: 34254834] - Fahimeh Haghighatdoost, Reyhaneh Sadeghian, Behnood Abbasi. The Associations Between Tea and Coffee Drinking and Risk of Calcium-Oxalate Renal Stones.
Plant foods for human nutrition (Dordrecht, Netherlands).
2021 Dec; 76(4):516-522. doi:
10.1007/s11130-021-00933-4
. [PMID: 34735676] - Xingyue Yang, Shun Yao, Jiaxing An, Hai Jin, Hui Wang, Biguang Tuo. SLC26A6 and NADC‑1: Future direction of nephrolithiasis and calculus‑related hypertension research (Review).
Molecular medicine reports.
2021 Nov; 24(5):. doi:
10.3892/mmr.2021.12385
. [PMID: 34458928] - Stavros A Kavouras, Hyun-Gyu Suh, Marion Vallet, Michel Daudon, Andy Mauromoustakos, Mariacristina Vecchio, Ivan Tack. Urine osmolality predicts calcium-oxalate crystallization risk in patients with recurrent urolithiasis.
Urolithiasis.
2021 Oct; 49(5):399-405. doi:
10.1007/s00240-020-01242-2
. [PMID: 33635363] - Kevin Shee, Justin Ahn, Fadl Hamouche, Jorge Mena, Thomas Chi, Marshall L Stoller. Nedosiran Dramatically Reduces Serum Oxalate in Dialysis-Dependent Primary Hyperoxaluria 1: A Compassionate Use Case Report.
Urology.
2021 Oct; 156(?):e147-e149. doi:
10.1016/j.urology.2021.03.014
. [PMID: 33774044] - Nariman R Soliman, Baher A M Effat, Nayra Sh Mehanna, Nabil F Tawfik, Mohamed K Ibrahim. Activity of probiotics from food origin for oxalate degradation.
Archives of microbiology.
2021 Oct; 203(8):5017-5028. doi:
10.1007/s00203-021-02484-3
. [PMID: 34282467] - Aimin Lv, Wuwu Wen, Nana Fan, Liantai Su, Peng Zhou, Yuan An. Dehydrin MsDHN1 improves aluminum tolerance of alfalfa (Medicago sativa L.) by affecting oxalate exudation from root tips.
The Plant journal : for cell and molecular biology.
2021 10; 108(2):441-458. doi:
10.1111/tpj.15451
. [PMID: 34363255] - Rattiyaporn Kanlaya, Chonnicha Subkod, Supanan Nanthawuttiphan, Visith Thongboonkerd. Caffeine prevents oxalate-induced epithelial-mesenchymal transition of renal tubular cells by its anti-oxidative property through activation of Nrf2 signaling and suppression of Snail1 transcription factor.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2021 Sep; 141(?):111870. doi:
10.1016/j.biopha.2021.111870
. [PMID: 34246192] - Anja Pfau, Theresa Ermer, Steven G Coca, Maria Clarissa Tio, Bernd Genser, Martin Reichel, Fredric O Finkelstein, Winfried März, Christoph Wanner, Sushrut S Waikar, Kai-Uwe Eckardt, Peter S Aronson, Christiane Drechsler, Felix Knauf. High Oxalate Concentrations Correlate with Increased Risk for Sudden Cardiac Death in Dialysis Patients.
Journal of the American Society of Nephrology : JASN.
2021 09; 32(9):2375-2385. doi:
10.1681/asn.2020121793
. [PMID: 34281958] - Cristina Martin-Higueras, Sander F Garrelfs, Jaap W Groothoff, Dorrit E Jacob, Shabbir H Moochhala, Justine Bacchetta, Cecile Acquaviva, Marcin Zaniew, Przymyslaw Sikora, Bodo B Beck, Bernd Hoppe. A report from the European Hyperoxaluria Consortium (OxalEurope) Registry on a large cohort of patients with primary hyperoxaluria type 3.
Kidney international.
2021 09; 100(3):621-635. doi:
10.1016/j.kint.2021.03.031
. [PMID: 33865885] - Steven L Daniel, Luke Moradi, Henry Paiste, Kyle D Wood, Dean G Assimos, Ross P Holmes, Lama Nazzal, Marguerite Hatch, John Knight. Forty Years of Oxalobacter formigenes, a Gutsy Oxalate-Degrading Specialist.
Applied and environmental microbiology.
2021 08; 87(18):e0054421. doi:
10.1128/aem.00544-21
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