hemanthamine (BioDeep_00000840395)
代谢物信息卡片
hemanthamine
化学式: C17H19NO4 (301.1314014)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC1CC2C3(C=C1)C(CN2CC4=CC5=C(C=C34)OCO5)O
InChI: InChI=1S/C17H19NO4/c1-20-11-2-3-17-12-6-14-13(21-9-22-14)4-10(12)7-18(8-16(17)19)15(17)5-11/h2-4,6,11,15-16,19H,5,7-9H2,1H3/t11-,15+,16-,17+/m1/s1
相关代谢途径
Reactome(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Deborah Kimie Yonamine, Vitor Eduardo Narciso Dos Reis, Amanda Eiriz Feu, Warley de Souza Borges, Carmen Lúcia Cardoso, Taisa Magnani Dinamarco. Ligand fishing approach to explore Amaryllidaceae alkaloids as potential antiviral candidates targeting SARS-CoV-2 Nsp4.
Journal of pharmaceutical and biomedical analysis.
2023 Dec; 240(?):115935. doi:
10.1016/j.jpba.2023.115935. [PMID: 38181554] - Christine J Kempthorne, Suresh Borra, Manoj Kumar, Chanti Babu Dokuburra, David K Liscombe, James McNulty. Identification of haemanthamine as a phytotoxic alkaloid in Narcissus pseudonarcissus L. (Daffodil) emerging buds.
Natural product research.
2023 Feb; ?(?):1-7. doi:
10.1080/14786419.2023.2174536. [PMID: 36744673] - Veronique Mathieu, Breana Laguera, Marco Masi, Sara Adriana Dulanto, Tanner W Bingham, Lucas W Hernandez, David Sarlah, Antonio Evidente, Denis L J Lafontaine, Alexander Kornienko, Michelle A Lane. Amaryllidaceae Alkaloids Decrease the Proliferation, Invasion, and Secretion of Clinically Relevant Cytokines by Cultured Human Colon Cancer Cells.
Biomolecules.
2022 09; 12(9):. doi:
10.3390/biom12091267. [PMID: 36139106] - Daniel Zaragoza-Puchol, Javier E Ortiz, Alejandro A Orden, Marianela Sanchez, Jorge Palermo, Alejandro Tapia, Jaume Bastida, Gabriela E Feresin. Alkaloids Analysis of Habranthus cardenasianus (Amaryllidaceae), Anti-Cholinesterase Activity and Biomass Production by Propagation Strategies.
Molecules (Basel, Switzerland).
2021 Jan; 26(1):. doi:
10.3390/molecules26010192. [PMID: 33401696] - Darja Koutová, Negar Maafi, Radim Havelek, Lubomír Opletal, Gerald Blunden, Martina Řezáčová, Lucie Cahlíková. Chemical and Biological Aspects of Montanine-Type Alkaloids Isolated from Plants of the Amaryllidaceae Family.
Molecules (Basel, Switzerland).
2020 May; 25(10):. doi:
10.3390/molecules25102337. [PMID: 32429491] - Deepali Katoch, Dharmesh Kumar, Yogendra S Padwad, Bikram Singh, Upendra Sharma. Narciclasine-4-O-β-D-xylopyranoside, a new narciclasine glycoside from Zephyranthes minuta.
Natural product research.
2020 Jan; 34(2):233-240. doi:
10.1080/14786419.2018.1527836. [PMID: 30636443] - Tonino G Adessi, José L Borioni, Natalia B Pigni, Jaume Bastida, Valeria Cavallaro, Ana P Murray, Marcelo Puiatti, Juan C Oberti, Segundo Leiva, Viviana E Nicotra, Manuela E Garcia. Clinanthus microstephium, an Amaryllidaceae Species with Cholinesterase Inhibitor Alkaloids: Structure-Activity Analysis of Haemanthamine Skeleton Derivatives.
Chemistry & biodiversity.
2019 May; 16(5):e1800662. doi:
10.1002/cbdv.201800662. [PMID: 30801949] - Suresh Borra, Ringaile Lapinskaite, Christine Kempthorne, David Liscombe, James McNulty, Tomas Hudlicky. Isolation, Synthesis, and Semisynthesis of Amaryllidaceae Constituents from Narcissus and Galanthus sp.: De Novo Total Synthesis of 2- epi-Narciclasine.
Journal of natural products.
2018 06; 81(6):1451-1459. doi:
10.1021/acs.jnatprod.8b00218. [PMID: 29787267] - Devashan Naidoo, Lenka Poštová Slavětínská, Adeyemi O Aremu, Jiri Gruz, Ondrej Biba, Karel Doležal, Johannes Van Staden, Jeffrey F Finnie. Metabolite profiling and isolation of biologically active compounds from Scadoxus puniceus, a highly traded South African medicinal plant.
Phytotherapy research : PTR.
2018 Apr; 32(4):625-630. doi:
10.1002/ptr.6000. [PMID: 29226479] - Miloš Hroch, Stanislav Mičuda, Radim Havelek, Jolana Cermanová, Lucie Cahlíková, Anna Hošťálková, Daniela Hulcová, Martina Řezáčová. LC-MS/MS method for the determination of haemanthamine in rat plasma, bile and urine and its application to a pilot pharmacokinetic study.
Biomedical chromatography : BMC.
2016 Jul; 30(7):1083-1091. doi:
10.1002/bmc.3653. [PMID: 26577707] - Radim Havelek, Martina Seifrtova, Karel Kralovec, Lenka Bruckova, Lucie Cahlikova, Marketa Dalecka, Jirina Vavrova, Martina Rezacova, Lubomir Opletal, Zuzana Bilkova. The effect of Amaryllidaceae alkaloids haemanthamine and haemanthidine on cell cycle progression and apoptosis in p53-negative human leukemic Jurkat cells.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2014 Mar; 21(4):479-90. doi:
10.1016/j.phymed.2013.09.005. [PMID: 24182986] - Andrea Lubbe, Henk Gude, Robert Verpoorte, Young Hae Choi. Seasonal accumulation of major alkaloids in organs of pharmaceutical crop Narcissus Carlton.
Phytochemistry.
2013 Apr; 88(?):43-53. doi:
10.1016/j.phytochem.2012.12.008. [PMID: 23318143] - Deepali Katoch, Shiv Kumar, Neeraj Kumar, Bikram Singh. Simultaneous quantification of Amaryllidaceae alkaloids from Zephyranthes grandiflora by UPLC-DAD/ESI-MS/MS.
Journal of pharmaceutical and biomedical analysis.
2012 Dec; 71(?):187-92. doi:
10.1016/j.jpba.2012.08.001. [PMID: 22939505] - Jerald J Nair, Lucie Rárová, Miroslav Strnad, Jaume Bastida, Johannes van Staden. Apoptosis-inducing effects of distichamine and narciprimine, rare alkaloids of the plant family Amaryllidaceae.
Bioorganic & medicinal chemistry letters.
2012 Oct; 22(19):6195-9. doi:
10.1016/j.bmcl.2012.08.005. [PMID: 22921081] - Jian-Sai Yang, Xu Feng, Yu Chen, Xing-Zeng Zhao, Ming Wang, Qi-Zhi Wang, Yun-Fa Dong. [Study on the chemical constituents from the bulbs of Zephyranthes candida].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2010 Nov; 33(11):1730-2. doi:
. [PMID: 21434434] - Strahil Berkov, Jaume Bastida, Reneta Tsvetkova, Francesc Viladomat, Carles Codina. Alkaloids from Sternbergia colchiciflora.
Zeitschrift fur Naturforschung. C, Journal of biosciences.
2009 May; 64(5-6):311-6. doi:
10.1515/znc-2009-5-601. [PMID: 19678530] - James McNulty, Jerald J Nair, Jaume Bastida, Siyaram Pandey, Carly Griffin. Structure activity studies on the crinane alkaloid apoptosis-inducing pharmacophore.
Natural product communications.
2009 Apr; 4(4):483-8. doi:
". [PMID: 19475990] - Susana López, Jaume Bastida, Francesc Viladomat, Carles Codina. Solid-phase extraction and reversed-phase high-performance liquid chromatography of the five major alkaloids in Narcissus confusus.
Phytochemical analysis : PCA.
2002 Nov; 13(6):311-5. doi:
10.1002/pca.660. [PMID: 12494748] - Judit Hohmann, Peter Forgo, Joseph Molnár, Krisztina Wolfard, Annamária Molnár, Theresia Thalhammer, Imre Máthé, Derek Sharples. Antiproliferative amaryllidaceae alkaloids isolated from the bulbs of Sprekelia formosissima and Hymenocallis x festalis.
Planta medica.
2002 May; 68(5):454-7. doi:
10.1055/s-2002-32068. [PMID: 12058326] - . .
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