Ferric nitrilotriacetate (BioDeep_00000840339)
代谢物信息卡片
Ferric nitrilotriacetate
化学式: C6H6FeNO6 (243.9544506)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(C(=O)[O-])N(CC(=O)[O-])CC(=O)[O-].[Fe+3]
InChI: /q
描述信息
D006401 - Hematologic Agents > D006397 - Hematinics > D005290 - Ferric Compounds
D009676 - Noxae > D002273 - Carcinogens
D009676 - Noxae > D009153 - Mutagens
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
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PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Sawsan El-Sonbaty, Eman I Kandil, Riham Abdel-Hamid Haroun. Assessment of the Antitumor Activity of Green Biosynthesized Zinc Nanoparticles as Therapeutic Agent Against Renal Cancer in Rats.
Biological trace element research.
2023 Jan; 201(1):272-281. doi:
10.1007/s12011-022-03126-5. [PMID: 35083709] - Fan Yang, Xiaoqiang Shi, Weidong Yang, Chao Gao, Zhenyu Cui, Wentao Wang. Pueraria montana (Kudzu vine) Ameliorate the Inflammation and Oxidative Stress against Fe-NTA Induced Renal Cancer.
Journal of oleo science.
2022 Sep; 71(10):1481-1492. doi:
10.5650/jos.ess22151. [PMID: 36089399] - Zhen Cheng, Shinya Akatsuka, Guang Hua Li, Kiyoshi Mori, Takashi Takahashi, Shinya Toyokuni. Ferroptosis resistance determines high susceptibility of murine A/J strain to iron-induced renal carcinogenesis.
Cancer science.
2022 Jan; 113(1):65-78. doi:
10.1111/cas.15175. [PMID: 34699654] - Mohammad Iqbal, Muhammad Dawood Shah, Senty Vun-Sang, Yasumasa Okazaki, Shigeru Okada. The therapeutic potential of curcumin in alleviating N-diethylnitrosamine and iron nitrilotriacetate induced renal cell tumours in mice via inhibition of oxidative stress: Implications for cancer chemoprevention.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2021 Jul; 139(?):111636. doi:
10.1016/j.biopha.2021.111636. [PMID: 33957566] - Aisha Siddiqi, Bano Saidullah, Sarwat Sultana. Anti-carcinogenic effect of hesperidin against renal cell carcinoma by targeting COX-2/PGE2 pathway in Wistar rats.
Environmental toxicology.
2018 Oct; 33(10):1069-1077. doi:
10.1002/tox.22626. [PMID: 30098279] - Guang Hua Li, Shinya Akatsuka, Shan Hwu Chew, Li Jiang, Takahiro Nishiyama, Akihiko Sakamoto, Takashi Takahashi, Mitsuru Futakuchi, Hiromu Suzuki, Kunihiko Sakumi, Yusaku Nakabeppu, Shinya Toyokuni. Fenton reaction-induced renal carcinogenesis in Mutyh-deficient mice exhibits less chromosomal aberrations than the rat model.
Pathology international.
2017 Nov; 67(11):564-574. doi:
10.1111/pin.12598. [PMID: 29027306] - Donald J Messner, Christine Surrago, Celia Fiordalisi, Wing Yin Chung, Kris V Kowdley. Isolation and characterization of iron chelators from turmeric (Curcuma longa): selective metal binding by curcuminoids.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine.
2017 Oct; 30(5):699-708. doi:
10.1007/s10534-017-0038-6. [PMID: 28801864] - Antonella Rosa, Angela Atzeri, Mariella Nieddu, Giovanni Appendino. New insights into the antioxidant activity and cytotoxicity of arzanol and effect of methylation on its biological properties.
Chemistry and physics of lipids.
2017 06; 205(?):55-64. doi:
10.1016/j.chemphyslip.2017.05.001. [PMID: 28476462] - Francine Tankeu Nzufo, Constant Anatole Pieme, Jacques Romain Njimou, Prosper Cabral Biapa Nya, Bruno Moukette Moukette, Bravi Marco, Chianese Angelo, Ngogang Jeanne Yonkeu. Organo-protective and antioxidant properties of leaf extracts of Syzygium guineense var macrocarpum against ferric nitriloacetate-induced stress of Wistar rats.
Journal of complementary & integrative medicine.
2017 Mar; 14(1):. doi:
10.1515/jcim-2015-0086. [PMID: 28214348] - Amita Verma, Prakash Chandra Bhatt, Gaurav Kaithwas, Nikunj Sethi, Mohd Rashid, Yashwant Singh, Mahfoozur Rahman, Fahad Al-Abbasi, Firoz Anwar, Vikas Kumar. Chemomodulatory effect Melastoma Malabathricum Linn against chemically induced renal carcinogenesis rats via attenuation of inflammation, oxidative stress, and early markers of tumor expansion.
Inflammopharmacology.
2016 Oct; 24(5):233-251. doi:
10.1007/s10787-016-0276-1. [PMID: 27628241] - Summya Rashid, Sana Nafees, Abul Vafa, Shekh Muhammad Afzal, Nemat Ali, Muneeb U Rehman, Syed Kazim Hasan, Aisha Siddiqi, Preeti Barnwal, Ferial Majed, Sarwat Sultana. Inhibition of precancerous lesions development in kidneys by chrysin via regulating hyperproliferation, inflammation and apoptosis at pre clinical stage.
Archives of biochemistry and biophysics.
2016 09; 606(?):1-9. doi:
10.1016/j.abb.2016.07.004. [PMID: 27403965] - Ramalingam Sharmila, Ganapathy Sindhu, Pushpam Marie Arockianathan. Nephroprotective effect of β-sitosterol on N-diethylnitrosamine initiated and ferric nitrilotriacetate promoted acute nephrotoxicity in Wistar rats.
Journal of basic and clinical physiology and pharmacology.
2016 Sep; 27(5):473-82. doi:
10.1515/jbcpp-2015-0085. [PMID: 26982615] - Francine Nzufo Tankeu, Constant Anatole Pieme, Cabral Prosper Biapa Nya, Romain Jacques Njimou, Bruno Moukette Moukette, Angelo Chianese, Jeanne Yonkeu Ngogang. In vitro organo-protective effect of bark extracts from Syzygium guineense var macrocarpum against ferric-nitrilotriacetate-induced stress in wistar rats homogenates.
BMC complementary and alternative medicine.
2016 Aug; 16(1):315. doi:
10.1186/s12906-016-1263-1. [PMID: 27561333] - S Ansar, M Iqbal. Antioxidant and nephroprotective potential of butylated hydroxyanisole against ferric nitrilotriacetate-induced oxidative stress and early tumor events.
Human & experimental toxicology.
2016 Apr; 35(4):448-53. doi:
10.1177/0960327115591378. [PMID: 26078281] - S Ansar, M Iqbal. Amelioration of ferric nitrilotriacetate-induced hepatotoxicity in Wistar rats by diallylsulfide.
Human & experimental toxicology.
2016 Mar; 35(3):259-66. doi:
10.1177/0960327115583362. [PMID: 25904316] - Aisha Siddiqi, Syed Kazim Hasan, Sana Nafees, Summya Rashid, Bano Saidullah, Sarwat Sultana. Chemopreventive efficacy of hesperidin against chemically induced nephrotoxicity and renal carcinogenesis via amelioration of oxidative stress and modulation of multiple molecular pathways.
Experimental and molecular pathology.
2015 Dec; 99(3):641-53. doi:
10.1016/j.yexmp.2015.11.012. [PMID: 26551080] - S Ansar, M Iqbal. Ameliorative effect of butylated hydroxyanisole against ferric nitrilotriacetate-induced hepatotoxicity and oxidative stress in rats.
Toxicology and industrial health.
2015 Nov; 31(11):967-73. doi:
10.1177/0748233714554409. [PMID: 26499990] - S Ansar, M Iqbal. Ascorbic acid inhibits ferric nitrilotriacetate induction of ornithine decarboxylase, DNA synthesis, oxidative stress, and hepatotoxicity in rats.
Toxicology and industrial health.
2015 Nov; 31(11):1008-14. doi:
10.1177/0748233713493824. [PMID: 23863956] - Karthikeyan Rajamani, V C Renju, S Sethupathy, Somasundaram S Thirugnanasambandan. Ameliorative effect of polyphenols from Padina boergesenii against ferric nitrilotriacetate induced renal oxidative damage: With inhibition of oxidative hemolysis and in vitro free radicals.
Environmental toxicology.
2015 Jul; 30(8):865-76. doi:
10.1002/tox.21951. [PMID: 24458998] - Francisco A Aguilar-Alonso, José D Solano, Chabetty Y Vargas-Olvera, Ignacio Pacheco-Bernal, Telma O Pariente-Pérez, María Elena Ibarra-Rubio. MAPKs' status at early stages of renal carcinogenesis and tumors induced by ferric nitrilotriacetate.
Molecular and cellular biochemistry.
2015 Jun; 404(1-2):161-70. doi:
10.1007/s11010-015-2375-5. [PMID: 25724684] - Kyoji Yoshino, Takashi Kanetaka, Kunimasa Koga. [Antioxidant Activity of Salacia Plant (Salacia reticulata)].
Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan.
2015; 56(4):144-50. doi:
10.3358/shokueishi.56.144. [PMID: 26346858] - S Ansar, M Iqbal, N AlJameil. Diallyl sulphide, a component of garlic, abrogates ferric nitrilotriacetate-induced oxidative stress and renal damage in rats.
Human & experimental toxicology.
2014 Dec; 33(12):1209-16. doi:
10.1177/0960327114524237. [PMID: 24596035] - Kannappan Poornima, Palanisamy Chella Perumal, Velliyur Kanniappan Gopalakrishnan. Protective effect of ethanolic extract of Tabernaemontana divaricata (L.) R. Br. against DEN and Fe NTA induced liver necrosis in Wistar Albino rats.
BioMed research international.
2014; 2014(?):240243. doi:
10.1155/2014/240243. [PMID: 25136566] - S Ansar, M Iqbal. Role of ascorbic acid in counteracting ferric nitrilotriacetate-induced nephrotoxicity in rats.
Pharmaceutical biology.
2013 Dec; 51(12):1559-63. doi:
10.3109/13880209.2013.802811. [PMID: 24024952] - Fang-Yin Li, Shao-Xing Zhu, Zong-Ping Wang, Hua Wang, Yang Zhao, Gui-Ping Chen. Consumption of hydrogen-rich water protects against ferric nitrilotriacetate-induced nephrotoxicity and early tumor promotional events in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2013 Nov; 61(?):248-54. doi:
10.1016/j.fct.2013.10.004. [PMID: 24140467] - S Ansar. Antioxidant effect of butylated hydroxytoluene on ferric nitrilotriacetate induced renal hyper proliferation and injury in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2013 Aug; 58(?):530-5. doi:
10.1016/j.fct.2013.04.054. [PMID: 23727425] - S Ansar, H Tabassum, N Al Jameil. Protective effect of butylated hydroxytoluene on ferric nitrilotriacetate induced hepatotoxicity and oxidative stress in mice.
Human & experimental toxicology.
2013 May; 32(5):513-21. doi:
10.1177/0960327113477876. [PMID: 23444334] - S Kobuchi, K Fukushima, H Aoyama, Y Ito, N Sugioka, K Takada. Effects of oxidative stress on the pharmacokinetics and hepatic metabolism of atazanavir in rats.
Free radical research.
2013 Apr; 47(4):291-300. doi:
10.3109/10715762.2013.770149. [PMID: 23351068] - Muneeb U Rehman, Mir Tahir, Abdul Quaiyoom Khan, Rehan Khan, Abdul Lateef, Oday-O-Hamiza, Wajhul Qamar, Farrah Ali, Sarwat Sultana. Chrysin suppresses renal carcinogenesis via amelioration of hyperproliferation, oxidative stress and inflammation: plausible role of NF-κB.
Toxicology letters.
2013 Feb; 216(2-3):146-58. doi:
10.1016/j.toxlet.2012.11.013. [PMID: 23194824] - Mehmet Yalaz, Erturk Levent, Murat Olukman, Sebnem Calkavur, Mete Akisu, Nilgun Kultursay. Role of digoxin-like immunoreactive substance in the pathogenesis of transient tachypnea of newborn.
BioMed research international.
2013; 2013(?):704763. doi:
10.1155/2013/704763. [PMID: 23936837] - Chabetty Y Vargas-Olvera, Dolores Javier Sánchez-González, José D Solano, Francisco A Aguilar-Alonso, Fernando Montalvo-Muñoz, Claudia María Martínez-Martínez, Omar N Medina-Campos, María Elena Ibarra-Rubio. Characterization of N-diethylnitrosamine-initiated and ferric nitrilotriacetate-promoted renal cell carcinoma experimental model and effect of a tamarind seed extract against acute nephrotoxicity and carcinogenesis.
Molecular and cellular biochemistry.
2012 Oct; 369(1-2):105-17. doi:
10.1007/s11010-012-1373-0. [PMID: 22761015] - Shinji Kobuchi, Keizo Fukushima, Yukako Ito, Nobuyuki Sugioka, Kanji Takada. Pharmacokinetics and distribution of fluvoxamine to the brain in rats under oxidative stress.
Free radical research.
2012 Jul; 46(7):831-41. doi:
10.3109/10715762.2012.683430. [PMID: 22486632] - Samuel E Schriner, Niki S Katoozi, Kevin Q Pham, Maral Gazarian, Asghar Zarban, Mahtab Jafari. Extension of Drosophila lifespan by Rosa damascena associated with an increased sensitivity to heat.
Biogerontology.
2012 Apr; 13(2):105-17. doi:
10.1007/s10522-011-9357-0. [PMID: 21928072] - Kyong-Son Min, Naomi Kishi, Nozomu Yamashita, Keiichi Tanaka. Oxidation and turnover of renal metallothioneins after an injection of ferric nitrilotriacetate.
Chemico-biological interactions.
2012 Jan; 195(1):61-7. doi:
10.1016/j.cbi.2011.09.006. [PMID: 22001350] - Noppawan Phumala Morales, Yumiko Yamaguchi, Kimiyo Murakami, Nuttavut Kosem, Hideo Utsumi. Hepatic reduction of carbamoyl-PROXYL in ferric nitrilotriacetate induced iron overloaded mice: an in vivo ESR study.
Biological & pharmaceutical bulletin.
2012; 35(7):1035-40. doi:
10.1248/bpb.b110701. [PMID: 22791149] - Shinji Kobuchi, Keizo Fukushima, Hiroaki Aoyama, Tatsuma Matsuda, Yukako Ito, Nobuyuki Sugioka, Kanji Takada. Effect of oxidative stress on the pharmacokinetics of clomipramine in rats treated with ferric-nitrilotriacetate.
Drug metabolism letters.
2011 Dec; 5(4):243-52. doi:
10.2174/187231211798472548. [PMID: 22022866] - Shiekh Tanveer Ahmad, Wani Arjumand, Amlesh Seth, Sana Nafees, Summya Rashid, Nemat Ali, Sarwat Sultana. Preclinical renal cancer chemopreventive efficacy of geraniol by modulation of multiple molecular pathways.
Toxicology.
2011 Nov; 290(1):69-81. doi:
10.1016/j.tox.2011.08.020. [PMID: 21907755] - Muneeb U Rehman, Sarwat Sultana. Attenuation of oxidative stress, inflammation and early markers of tumor promotion by caffeic acid in Fe-NTA exposed kidneys of Wistar rats.
Molecular and cellular biochemistry.
2011 Nov; 357(1-2):115-24. doi:
10.1007/s11010-011-0881-7. [PMID: 21647614] - Toyohiro Kato, Hiroaki Kawaguchi, Noriaki Miyoshi, Kohji Aoyama, Masaharu Komatsu, Masahisa Horiuchi, Hiroki Yoshida, Toru Takeuchi. Effect of habitual exercise on renal carcinogenesis by ferric nitrilotriacetate.
Environmental health and preventive medicine.
2011 Jul; 16(4):232-8. doi:
10.1007/s12199-010-0191-9. [PMID: 21431792] - Hiroki Ohara, Shinya Akatsuka, Hirotaka Nagai, Yu-Ting Liu, Li Jiang, Yasumasa Okazaki, Yoriko Yamashita, Tomoyuki Nakamura, Shinya Toyokuni. Stage-specific roles of fibulin-5 during oxidative stress-induced renal carcinogenesis in rats.
Free radical research.
2011 Feb; 45(2):211-20. doi:
10.3109/10715762.2010.523702. [PMID: 20942562] - Gurpreet Kaur, Mohammad Athar, M Sarwar Alam. Dietary supplementation of silymarin protects against chemically induced nephrotoxicity, inflammation and renal tumor promotion response.
Investigational new drugs.
2010 Oct; 28(5):703-13. doi:
10.1007/s10637-009-9289-6. [PMID: 19590824] - Anne Auriac, Alexandra Willemetz, François Canonne-Hergaux. Lipid raft-dependent endocytosis: a new route for hepcidin-mediated regulation of ferroportin in macrophages.
Haematologica.
2010 Aug; 95(8):1269-77. doi:
10.3324/haematol.2009.019992. [PMID: 20220061] - Mohammad Iqbal, Muhammad Dawood Shah, Chau Ann Lie, Chin Kim San. Strobilanthes crispus attenuates renal carcinogen, iron nitrilotriacetate (Fe-NTA)-mediated oxidative damage of lipids and DNA.
Molecular and cellular biochemistry.
2010 Aug; 341(1-2):271-7. doi:
10.1007/s11010-010-0458-x. [PMID: 20376534] - Galina Hovhannisyan, Rouben Aroutiounian, Michael Glei. Butyrate reduces the frequency of micronuclei in human colon carcinoma cells in vitro.
Toxicology in vitro : an international journal published in association with BIBRA.
2009 Sep; 23(6):1028-33. doi:
10.1016/j.tiv.2009.06.011. [PMID: 19539745] - Daisaku Yoshihara, Noriko Fujiwara, Tomomi Ookawara, Shinsuke Kato, Haruhiko Sakiyama, Shunichi Yokoe, Hironobu Eguchi, Keiichiro Suzuki. Protective role of glutathione S-transferase A4 induced in copper/zinc-superoxide dismutase knockout mice.
Free radical biology & medicine.
2009 Sep; 47(5):559-67. doi:
10.1016/j.freeradbiomed.2009.05.022. [PMID: 19482077] - Mohammad Iqbal, Yasumasa Okazaki, Shigeru Okada. Curcumin attenuates oxidative damage in animals treated with a renal carcinogen, ferric nitrilotriacetate (Fe-NTA): implications for cancer prevention.
Molecular and cellular biochemistry.
2009 Apr; 324(1-2):157-64. doi:
10.1007/s11010-008-9994-z. [PMID: 19165575] - Amit Gupta, Sameer Sharma, Indupal Kaur, Kanwaljit Chopra. Renoprotective effects of sesamol in ferric nitrilotriacetate-induced oxidative renal injury in rats.
Basic & clinical pharmacology & toxicology.
2009 Apr; 104(4):316-21. doi:
10.1111/j.1742-7843.2009.00381.x. [PMID: 19281599] - Amitt Gupta, Kanwaljit Chopra. Effect of tocotrienols on iron-induced renal dysfunction and oxidative stress in rats.
Drug and chemical toxicology.
2009; 32(4):319-25. doi:
10.1080/01480540903130633. [PMID: 19793023] - Ichiro Nakatsuka, Shigeru Maeda, Tsugunobu Andoh, Yukiko Hayashi, Ryuichiro Mizuno, Hitoshi Higuchi, Takuya Miyawaki. Oxidative changes in the rat brain by intraperitoneal injection of ferric nitrilotriacetate.
Redox report : communications in free radical research.
2009; 14(3):109-14. doi:
10.1179/135100009x392575. [PMID: 19490752] - Gurpreet Kaur, Irshad A Lone, Mohammad Athar, M Sarwar Alam. Guilandina bonduc L. possesses antioxidant activity and precludes Ferric Nitrilotriacetate (Fe-NTA) induced renal toxicity and tumor promotion response.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer.
2009; 28(2):163-75. doi:
10.1615/jenvironpatholtoxicoloncol.v28.i2.80. [PMID: 19817703] - Yuji Tanaka, Lauren M Aleksunes, Michael J Goedken, Chuan Chen, Scott A Reisman, José E Manautou, Curtis D Klaassen. Coordinated induction of Nrf2 target genes protects against iron nitrilotriacetate (FeNTA)-induced nephrotoxicity.
Toxicology and applied pharmacology.
2008 Sep; 231(3):364-73. doi:
10.1016/j.taap.2008.05.022. [PMID: 18617210] - Dur-Zong Hsu, Chang-Hsin Wan, Hua-Fen Hsu, Yung-Ming Lin, Ming-Yie Liu. The prophylactic protective effect of sesamol against ferric-nitrilotriacetate-induced acute renal injury in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2008 Aug; 46(8):2736-41. doi:
10.1016/j.fct.2008.04.029. [PMID: 18539378] - Hang Guo, Ai Ekusa, Koji Iwai, Masami Yonekura, Yoshihisa Takahata, Fumiki Morimatsu. Royal jelly peptides inhibit lipid peroxidation in vitro and in vivo.
Journal of nutritional science and vitaminology.
2008 Jun; 54(3):191-5. doi:
10.3177/jnsv.54.191. [PMID: 18635904] - V Eybl, D Kotyzová, P Cerná, J Koutensky. Effect of melatonin, curcumin, quercetin, and resveratrol on acute ferric nitrilotriacetate (Fe-NTA)-induced renal oxidative damage in rats.
Human & experimental toxicology.
2008 Apr; 27(4):347-53. doi:
10.1177/0960327108094508. [PMID: 18684806] - A Mizote, Y Okazaki, M Iqbal, S Okada. Antioxidant biofactor, a processed grain food, inhibits iron nitrilotriacetate-induced renal tumorigenesis, hyperproliferative response, and oxidative damage.
Human & experimental toxicology.
2008 Mar; 27(3):207-14. doi:
10.1177/0960327107087795. [PMID: 18650252] - Keita Kanki, Takashi Umemura, Yasuki Kitamura, Yuji Ishii, Yuichi Kuroiwa, Yukio Kodama, Ken Itoh, Masayuki Yamamoto, Akiyoshi Nishikawa, Masao Hirose. A possible role of nrf2 in prevention of renal oxidative damage by ferric nitrilotriacetate.
Toxicologic pathology.
2008 Feb; 36(2):353-61. doi:
10.1177/0192623307311401. [PMID: 18364461] - Amit Gupta, Sameer Sharma, Kanwaljit Chopra. Reversal of iron-induced nephrotoxicity in rats by molsidomine, a nitric oxide donor.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2008 Feb; 46(2):537-43. doi:
10.1016/j.fct.2007.08.041. [PMID: 17935848] - Yu-Ting Liu, Donghao Shang, Shinya Akatsuka, Hiroki Ohara, Khokon Kumar Dutta, Katsura Mizushima, Yuji Naito, Toshikazu Yoshikawa, Masashi Izumiya, Kouichiro Abe, Hitoshi Nakagama, Noriko Noguchi, Shinya Toyokuni. Chronic oxidative stress causes amplification and overexpression of ptprz1 protein tyrosine phosphatase to activate beta-catenin pathway.
The American journal of pathology.
2007 Dec; 171(6):1978-88. doi:
10.2353/ajpath.2007.070741. [PMID: 18055543] - Shunji Ueno, Takashige Kashimoto, Nobuyuki Susa, Kensuke Shiho, Takashi Seki, Nobuhiko Ito, Shino Takeda-Homma, Yoshikazu Nishimura, Masayasu Sugiyama. Estimation of hydroxyl radical generation by salicylate hydroxylation method in kidney of mice exposed to ferric nitrilotriacetate and potassium bromate.
Free radical research.
2007 Nov; 41(11):1246-52. doi:
10.1080/10715760701644019. [PMID: 17907000] - Irshad A Lone, Gurpreet Kaur, Mohammad Athar, M Sarwar Alam. Protective effect of Rumex patientia (English Spinach) roots on ferric nitrilotriacetate (Fe-NTA) induced hepatic oxidative stress and tumor promotion response.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2007 Oct; 45(10):1821-9. doi:
10.1016/j.fct.2007.03.021. [PMID: 17517459] - She-Fang Ye, Zhen-Qing Hou, Qi-Qing Zhang. Protective effects of Phellinus linteus extract against iron overload-mediated oxidative stress in cultured rat hepatocytes.
Phytotherapy research : PTR.
2007 Oct; 21(10):948-53. doi:
10.1002/ptr.2182. [PMID: 17602436] - L Prasad, T H Khan, T Jahangir, S Sultana. Abrogation of DEN/Fe-NTA induced carcinogenic response, oxidative damage and subsequent cell proliferation response by Terminalia chebula in kidney of Wistar rats.
Die Pharmazie.
2007 Oct; 62(10):790-7. doi:
. [PMID: 18236787] - Mohammad Iqbal, Yasumasa Okazaki, Shigeru Okada. Probucol modulates iron nitrilotriacetate (Fe-NTA)-dependent renal carcinogenesis and hyperproliferative response: diminution of oxidative stress.
Molecular and cellular biochemistry.
2007 Oct; 304(1-2):61-9. doi:
10.1007/s11010-007-9486-6. [PMID: 17487455] - Mukesh Kumar Agarwal, Mohammad Iqbal, Mohammad Athar. Garlic oil ameliorates ferric nitrilotriacetate (Fe-NTA)-induced damage and tumor promotion: implications for cancer prevention.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2007 Sep; 45(9):1634-40. doi:
10.1016/j.fct.2007.02.029. [PMID: 17512651] - Amit Gupta, Vikas Chander, Sameer Sharma, Kanwaljit Chopra. Sodium nitroprusside and L-arginine attenuates ferric nitrilotriacetate-induced oxidative renal injury in rats.
Toxicology.
2007 Apr; 232(3):183-91. doi:
10.1016/j.tox.2007.01.009. [PMID: 17280760] - Kyong-Son Min. [Physiological significance of metallothionein in oxidative stress].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
2007 Apr; 127(4):695-702. doi:
10.1248/yakushi.127.695. [PMID: 17409699] - Gurpreet Kaur, Irshad A Lone, Mohammad Athar, M Sarwar Alam. Protective effect of Didymocarpus pedicellata on ferric nitrilotriacetate (Fe-NTA) induced renal oxidative stress and hyperproliferative response.
Chemico-biological interactions.
2007 Jan; 165(1):33-44. doi:
10.1016/j.cbi.2006.10.012. [PMID: 17140554] - Ryuichiro Mizuno, Teruyuki Kawabata, Yuichi Sutoh, Yuzo Nishida, Shigeru Okada. Oxidative renal tubular injuries induced by aminocarboxylate-type iron (III) coordination compounds as candidate renal carcinogens.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine.
2006 Dec; 19(6):675-83. doi:
10.1007/s10534-006-9004-4. [PMID: 16670936] - Li Jiang, Yi Zhong, Shinya Akatsuka, Yu-Ting Liu, Khokon Kumar Dutta, Wen-Hua Lee, Janice Onuki, Ken-ichi Masumura, Takehiko Nohmi, Shinya Toyokuni. Deletion and single nucleotide substitution at G:C in the kidney of gpt delta transgenic mice after ferric nitrilotriacetate treatment.
Cancer science.
2006 Nov; 97(11):1159-67. doi:
10.1111/j.1349-7006.2006.00301.x. [PMID: 16925583] - Tamanna Jahangir, Sarwat Sultana. Modulatory effects of Pluchea lanceolata against chemically induced oxidative damage, hyperproliferation and two-stage renal carcinogenesis in Wistar rats.
Molecular and cellular biochemistry.
2006 Oct; 291(1-2):175-85. doi:
10.1007/s11010-006-9213-8. [PMID: 16767495] - Wen-Hua Lee, Shinya Akatsuka, Tomoyuki Shirase, Khokon Kumar Dutta, Li Jiang, Yu-Ting Liu, Janice Onuki, Yoshihiro Yamada, Katsuya Okawa, Youichiro Wada, Akira Watanabe, Takahide Kohro, Noriko Noguchi, Shinya Toyokuni. Alpha-tocopherol induces calnexin in renal tubular cells: another protective mechanism against free radical-induced cellular damage.
Archives of biochemistry and biophysics.
2006 Sep; 453(2):168-78. doi:
10.1016/j.abb.2006.07.002. [PMID: 16908007] - Lakshmi Prasad, Tajdar Husain Khan, Tamanna Jahangir, Sarwat Sultana. Effect of gallic acid on renal biochemical alterations in male Wistar rats induced by ferric nitriloacetic acid.
Human & experimental toxicology.
2006 Sep; 25(9):523-9. doi:
10.1191/0960327106het652oa. [PMID: 17017005] - Fahim Atif, Manpreet Kaur, Seema Yousuf, Sheikh Raisuddin. In vitro free radical scavenging activity of hepatic metallothionein induced in an Indian freshwater fish, Channa punctata Bloch.
Chemico-biological interactions.
2006 Aug; 162(2):172-80. doi:
10.1016/j.cbi.2006.06.006. [PMID: 16872588] - Gurpreet Kaur, Zoobi Jabbar, Mohammad Athar, M Sarwar Alam. Punica granatum (pomegranate) flower extract possesses potent antioxidant activity and abrogates Fe-NTA induced hepatotoxicity in mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.
2006 Jul; 44(7):984-93. doi:
10.1016/j.fct.2005.12.001. [PMID: 16426722] - Tamanna Jahangir, Tajdar Husain Khan, Lakshmi Prasad, Sarwat Sultana. Farnesol prevents Fe-NTA-mediated renal oxidative stress and early tumour promotion markers in rats.
Human & experimental toxicology.
2006 May; 25(5):235-42. doi:
10.1191/0960327106ht616oa. [PMID: 16758765] - H R Matos, S A Marques, O F Gomes, A A Silva, J C Heimann, P Di Mascio, M H G Medeiros. Lycopene and beta-carotene protect in vivo iron-induced oxidative stress damage in rat prostate.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.
2006 Feb; 39(2):203-10. doi:
10.1590/s0100-879x2006000200006. [PMID: 16470307] - Junya Uwayama, Aki Hirayama, Toru Yanagawa, Eiji Warabi, Rika Sugimoto, Ken Itoh, Masayuki Yamamoto, Hiroshi Yoshida, Akio Koyama, Tetsuro Ishii. Tissue Prx I in the protection against Fe-NTA and the reduction of nitroxyl radicals.
Biochemical and biophysical research communications.
2006 Jan; 339(1):226-31. doi:
10.1016/j.bbrc.2005.10.192. [PMID: 16297875] - Munetaka Ozeki, Aya Miyagawa-Hayashino, Shinya Akatsuka, Tomoyuki Shirase, Wen-Hua Lee, Koji Uchida, Shinya Toyokuni. Susceptibility of actin to modification by 4-hydroxy-2-nonenal.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2005 Nov; 827(1):119-26. doi:
10.1016/j.jchromb.2005.02.025. [PMID: 15886073] - Antonella Rosa, Monica Deiana, Giulia Corona, Angela Atzeri, Alessandra Incani, Giovanni Appendino, M Assunta Dessì. Protective effect of capsinoid on lipid peroxidation in rat tissues induced by Fe-NTA.
Free radical research.
2005 Nov; 39(11):1155-62. doi:
10.1080/10715760500178094. [PMID: 16298741] - N S Ahmad, B A K Khalid, D A Luke, S Ima Nirwana. Tocotrienol offers better protection than tocopherol from free radical-induced damage of rat bone.
Clinical and experimental pharmacology & physiology.
2005 Sep; 32(9):761-70. doi:
10.1111/j.1440-1681.2005.04264.x. [PMID: 16173934] - Koji Nakatani, Masaharu Komatsu, Toyohiro Kato, Takao Yamanaka, Hiroaki Takekura, Akira Wagatsuma, Kohji Aoyama, Baohui Xu, Takeshi Hirano, Hiroshi Kasai, Seiichi Ando, Toru Takeuchi. Habitual exercise induced resistance to oxidative stress.
Free radical research.
2005 Sep; 39(9):905-11. doi:
10.1080/10715760500183300. [PMID: 16087471] - Yasumasa Okazaki, Mohammad Iqbal, Shigeru Okada. Suppressive effects of dietary curcumin on the increased activity of renal ornithine decarboxylase in mice treated with a renal carcinogen, ferric nitrilotriacetate.
Biochimica et biophysica acta.
2005 Jun; 1740(3):357-66. doi:
10.1016/j.bbadis.2004.09.006. [PMID: 15949703] - Khokon K Dutta, Yumiko Nishinaka, Hiroshi Masutani, Shinya Akatsuka, Than T Aung, Tomoyuki Shirase, Wen-Hua Lee, Yoshihiro Yamada, Hiroshi Hiai, Junji Yodoi, Shinya Toyokuni. Two distinct mechanisms for loss of thioredoxin-binding protein-2 in oxidative stress-induced renal carcinogenesis.
Laboratory investigation; a journal of technical methods and pathology.
2005 Jun; 85(6):798-807. doi:
10.1038/labinvest.3700280. [PMID: 15834431] - Antonella Rosa, Monica Deiana, Giulia Corona, Angela Atzeri, Alessandra Incani, M Assunta Dessì. Cholesterol as target of Fe-NTA-induced lipid peroxidation in rat tissues.
Toxicology letters.
2005 May; 157(1):1-8. doi:
10.1016/j.toxlet.2004.12.013. [PMID: 15795088] - N Khan, S Sultana. Inhibition of two stage renal carcinogenesis, oxidative damage and hyperproliferative response by Nigella sativa.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP).
2005 Apr; 14(2):159-68. doi:
10.1097/00008469-200504000-00012. [PMID: 15785320] - Kyong-Son Min, Fumio Morishita, Noriko Tetsuchikawahara, Satomi Onosaka. Induction of hepatic and renal metallothionein synthesis by ferric nitrilotriacetate in mice: the role of MT as an antioxidant.
Toxicology and applied pharmacology.
2005 Apr; 204(1):9-17. doi:
10.1016/j.taap.2004.08.014. [PMID: 15781289] - Naghma Khan, Sarwat Sultana. Anticarcinogenic effect of Nymphaea alba against oxidative damage, hyperproliferative response and renal carcinogenesis in Wistar rats.
Molecular and cellular biochemistry.
2005 Mar; 271(1-2):1-11. doi:
10.1007/s11010-005-2258-2. [PMID: 15881650] - Mukesh Kumar Agarwal, Mohammad Iqbal, Mohammad Athar. Vitamin E inhibits hepatic oxidative stress, toxicity and hyperproliferation in rats treated with the renal carcinogen ferric nitrilotriacetate.
Redox report : communications in free radical research.
2005; 10(2):62-70. doi:
10.1179/135100005x21642. [PMID: 15949125] - Gopala K Rangan, Yiping Wang, Yuet-Ching Tay, Jason D Coombes, David C H Harris. Effect of nephrotoxins on tubulointerstitial injury and NF-kappaB activation in Adriamycin nephropathy.
Renal failure.
2005; 27(5):609-14. doi:
10.1080/08860220500200437. [PMID: 16153002] - Monica Deiana, Antonella Rosa, Giulia Corona, Stefania Collu, Maria Grazia Ennas, Maria Assunta Dessì. Lipid peroxidation in plasma of rats treated with ferric-nitrilotriacetate, in relation to kidney and liver modifications.
BioFactors (Oxford, England).
2005; 23(1):35-44. doi:
10.1002/biof.5520230105. [PMID: 15817997] - Kaori Akai, Koichiro Tsuchiya, Akira Tokumura, Kentaro Kogure, Satoru Ueno, Akira Shibata, Toshiaki Tamaki, Kenji Fukuzawa. Ability of ferric nitrilotriacetate complex with three pH-dependent conformations to induce lipid peroxidation.
Free radical research.
2004 Sep; 38(9):951-62. doi:
10.1080/1071576042000261945. [PMID: 15621713] - Naghma Khan, Sarwat Sultana. Induction of renal oxidative stress and cell proliferation response by ferric nitrilotriacetate (Fe-NTA): diminution by soy isoflavones.
Chemico-biological interactions.
2004 Aug; 149(1):23-35. doi:
10.1016/j.cbi.2004.06.003. [PMID: 15294441] - Naghma Khan, Sonia Sharma, Sarwat Sultana. Amelioration of ferric nitrilotriacetate (Fe-NTA) induced renal oxidative stress and tumor promotion response by coumarin (1,2-benzopyrone) in Wistar rats.
Cancer letters.
2004 Jul; 210(1):17-26. doi:
10.1016/j.canlet.2004.01.011. [PMID: 15172116] - Devinder Singh, Vikas Chander, Kanwaljit Chopra. Quercetin, a bioflavonoid, attenuates ferric nitrilotriacetate-induced oxidative renal injury in rats.
Drug and chemical toxicology.
2004 May; 27(2):145-56. doi:
10.1081/dct-120030729. [PMID: 15198074] - Monica Deiana, Antonella Rosa, Viviana Casu, Rosaria Piga, M Assunta Dessì, Okezie I Aruoma. L-ergothioneine modulates oxidative damage in the kidney and liver of rats in vivo: studies upon the profile of polyunsaturated fatty acids.
Clinical nutrition (Edinburgh, Scotland).
2004 Apr; 23(2):183-93. doi:
10.1016/s0261-5614(03)00108-0. [PMID: 15030958] - She-Fang Ye, K Wakame, K Ichimura, S Matsuzaki. Amelioration by active hexose correlated compound of endocrine disturbances induced by oxidative stress in the rat.
Endocrine regulations.
2004 Mar; 38(1):7-13. doi:
NULL. [PMID: 15147233] - Kanwaljit Chopra, Devinder Singh, Vikas Chander. Nephrotoxicity and its prevention by catechin in ferric nitrilotriacetate promoted oxidative stress in rats.
Human & experimental toxicology.
2004 Mar; 23(3):137-43. doi:
10.1191/0960327104ht427oa. [PMID: 15119533] - Mohammad Iqbal, Som Datta Sharma, Shigeru Okada. Probucol as a potent inhibitor of oxygen radical-induced lipid peroxidation and DNA damage: in vitro studies.
Redox report : communications in free radical research.
2004; 9(3):167-72. doi:
10.1179/135100004225005174. [PMID: 15327747] - She-Fang Ye, Kaoru Ichimura, Koji Wakame, Masato Ohe. Suppressive effects of Active Hexose Correlated Compound on the increased activity of hepatic and renal ornithine decarboxylase induced by oxidative stress.
Life sciences.
2003 Dec; 74(5):593-602. doi:
10.1016/j.lfs.2003.06.038. [PMID: 14623030]