Fluorocholine F-18 (BioDeep_00000840167)
代谢物信息卡片
Fluorocholine F-18
化学式: C5H13FNO+ (122.0981)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C[N+](C)(CCO)CF
InChI: InChI=1S/C5H13FNO/c1-7(2,5-6)3-4-8/h8H,3-5H2,1-2H3/q+1/i6-1
描述信息
C1446 - Radiopharmaceutical Compound > C2124 - Radioconjugate
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
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PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Loic Ah-Thiane, Ludovic Ferrer, Bruno Maucherat, Vincent Fleury, Maelle Le Thiec, Daniela Rusu, Caroline Rousseau. Vaccine-Related Lymph Nodes: The Emerging Pitfalls of 18F-Fluorocholine and 68Ga-PSMA-11 PET/CT in the Era of COVID-19 Vaccination.
Clinical nuclear medicine.
2022 Jul; 47(7):575-582. doi:
10.1097/rlu.0000000000004190. [PMID: 35675134] - Domenico Albano, Giulia Volpi, Francesco Dondi, Raffaele Giubbini, Francesco Bertagna. COVID-19 Vaccination Manifesting as Unilateral Lymphadenopathies Detected by 18F-Choline PET/CT.
Clinical nuclear medicine.
2022 Feb; 47(2):e187-e189. doi:
10.1097/rlu.0000000000003951. [PMID: 34593692] - Andrzej Mazurek, Mirosław Dziuk, Ewa Witkowska-Patena, Witold Chudzinski, Stanisław Piszczek, Agnieszka Gizewska, Marek Saracyn. The utility of 18F-fluorocholine PET/CT in the imaging of parathyroid adenomas.
Endokrynologia Polska.
2022; 73(1):43-48. doi:
10.5603/ep.a2021.0107. [PMID: 35119087] - Lin Xiong, Weihua Wu, Yue Chen, Liang Cai, Santao Ou. High turnover renal osteodystrophy due to secondary hyperparathyroidism diagnosed by 18F-Fluorocholine combined with 18F-NaF PET/CT.
Renal failure.
2021 Dec; 43(1):882-885. doi:
10.1080/0886022x.2021.1918165. [PMID: 34011250] - Noha N Mukhtar, Mohei El-Din M Abouzied, Mohammed H Alqahtani, Muhammad M Hammami. Misleading localization by 18F-fluorocholine PET/CT in familial hypocalciuric hypercalcemia type-3: a case report.
BMC endocrine disorders.
2021 Jan; 21(1):20. doi:
10.1186/s12902-021-00683-z. [PMID: 33499837] - Léa Turpin, Quentin Pouliot, Jules Zhang, Martine Glikman, Florie Gomez, Jean-Noël Talbot, Françoise Montravers. 18F-Fluorocholine uptake matching CT lesions in the lungs of a patient clinically cured from COVID-19 syndrome.
European journal of nuclear medicine and molecular imaging.
2020 10; 47(11):2706-2708. doi:
10.1007/s00259-020-04919-3. [PMID: 32561970] - Nicolas de Leiris, Julien Leenhardt, Bastien Boussat, Christopher Montemagno, Alexandre Seiller, Olivier Phan Sy, Julie Roux, Mathieu Laramas, Camille Verry, Carole Iriart, Gaelle Fiard, Jean-Alexandre Long, Jean-Luc Descotes, Jean-Philippe Vuillez, Laurent Riou, Loïc Djaileb. Does whole-body bone SPECT/CT provide additional diagnostic information over [18F]-FCH PET/CT for the detection of bone metastases in the setting of prostate cancer biochemical recurrence?.
Cancer imaging : the official publication of the International Cancer Imaging Society.
2020 Aug; 20(1):58. doi:
10.1186/s40644-020-00333-y. [PMID: 32787923] - Ana María García Vicente, Ángel Soriano Castrejón. Incidental COVID-19 Pneumonia on 18F-Fluorocholine PET/CT.
Clinical nuclear medicine.
2020 Aug; 45(8):e376-e377. doi:
10.1097/rlu.0000000000003189. [PMID: 32520514] - Fabio Zattoni, Ilaria Ravelli, Marco Rensi, Decio Capobianco, Eugenio Borsatti, Tania Baresic, Agostino Chiaravalloti, Orazio Schillaci, Pierpaolo Alongi, Tommaso Vincenzo Bartolotta, Ilaria Rambaldi, Mirco Bartolomei, Mohsen Farsad, Manuel Tredici, Davide Donner, Franca Chierichetti, Giuseppe Trifirò, Elisabetta Brugola, Marta Burei, Fabrizio Dal Moro, Diego Cecchin, Laura Evangelista. 10-Year Clinical Experience With 18F-Choline PET/CT: An Italian Multicenter Retrospective Assessment of 3343 Patients.
Clinical nuclear medicine.
2020 Aug; 45(8):594-603. doi:
10.1097/rlu.0000000000003125. [PMID: 32558711] - J R Garcia, M Cozar, M Soler, P Bassa, E Riera, M Buxeda, E Valls, J Ferrer. Standardization of acquisition protocols using PET/CT with 18F-Choline in prostate cancer.
Revista espanola de medicina nuclear e imagen molecular.
2020 Jul; 39(4):204-211. doi:
10.1016/j.remn.2020.01.007. [PMID: 32192907] - Vincent Niziers, Romain Boissier, Delphine Borchiellini, Jean-Laurent Deville, Cédric Khoury, Matthieu Durand, Harry Toledano, Thomas Albert, Nicolas Branger, Quentin Bandelier, Matthieu-John Ouvrier, Sophie Gabriel, Benjamin Hoch, Emmanuel Gross, Jochen Walz, Isabelle Brenot-Rossi, Géraldine Pignot. 'Real-world' evaluation of 18F-Choline PET/CT practices in prostate cancer patients and impact on changes in therapeutic strategy.
Urologic oncology.
2020 01; 38(1):2.e1-2.e9. doi:
10.1016/j.urolonc.2019.07.017. [PMID: 31447087] - Angélique Gougelet, Chiara Sartor, Nadia Senni, Julien Calderaro, Laetitia Fartoux, Marie Lequoy, Dominique Wendum, Jean-Noël Talbot, Aurélie Prignon, Julia Chalaye, Sandrine Imbeaud, Jessica Zucman-Rossi, Thierry Tordjmann, Cécile Godard, Pascale Bossard, Olivier Rosmorduc, Giuliana Amaddeo, Sabine Colnot. Hepatocellular Carcinomas With Mutational Activation of Beta-Catenin Require Choline and Can Be Detected by Positron Emission Tomography.
Gastroenterology.
2019 09; 157(3):807-822. doi:
10.1053/j.gastro.2019.05.069. [PMID: 31194980] - Mathieu Gauthé, Cyrielle Aveline, Frédéric Lecouvet, Laure Michaud, Caroline Rousseau, Marc Tassart, Olivier Cussenot, Jean-Noël Talbot, Isabelle Durand-Zaleski. Impact of sodium 18F-fluoride PET/CT, 18F-fluorocholine PET/CT and whole-body diffusion-weighted MRI on the management of patients with prostate cancer suspicious for metastasis: a prospective multicentre study.
World journal of urology.
2019 Aug; 37(8):1587-1595. doi:
10.1007/s00345-018-2547-5. [PMID: 30382380] - Giordano Savelli, Mauro Morassi, Milena Cobelli, Antonella Stefanelli, Alberto Zaniboni. 18F-Fluorocholine Uptake by a Head and Neck Meningeal Inflammatory Pseudotumor.
Clinical nuclear medicine.
2019 Aug; 44(8):657-659. doi:
10.1097/rlu.0000000000002635. [PMID: 31274616] - Marina Villar, Manuel Valiente, María Toscano, Margalida Galmés, Carlos González, Marta Ortiz, Fernando Vega, Magdalena Oporto, Pedro Bibiloni, José Luis Chinchilla, Jesús Molina, Ángel Ríos, Cristina Peña, Sebastià Rubí. Development of a thin layer chromatography method for plasma correction of [18F]fluorocholine metabolites in positron emission tomography quantification studies in humans.
Nuclear medicine and biology.
2019 Jul; 74-75(?):34-40. doi:
10.1016/j.nucmedbio.2019.08.003. [PMID: 31473490] - Matthieu Barbaud, Mathieu Frindel, Ludovic Ferrer, Maelle Le Thiec, Daniela Rusu, Aurore Rauscher, Bruno Maucherat, Pierre Baumgartner, Vincent Fleury, Mathilde Colombié, Agnes Thierry-Morel, Françoise Kraeber-Bodéré, Loïc Campion, Caroline Rousseau. 68Ga-PSMA-11 PET-CT study in prostate cancer patients with biochemical recurrence and non-contributive 18F-Choline PET-CT: Impact on therapeutic decision-making and biomarker changes.
The Prostate.
2019 04; 79(5):454-461. doi:
10.1002/pros.23751. [PMID: 30549066] - Jiwan Paudel, Navneet Singla, Anish Bhattacharya, Rajender Kumar Basher, Bhagwant Rai Mittal. Incidental Detection of Plasma Cell Neoplasm on 18F-Choline PET/CT Imaging.
Clinical nuclear medicine.
2019 Feb; 44(2):140-141. doi:
10.1097/rlu.0000000000002415. [PMID: 30562192] - Eline E Verwer, Taylor R Kavanagh, William J Mischler, You Feng, Kazue Takahashi, Shuyan Wang, Timothy M Shoup, Ramesh Neelamegam, Jing Yang, Nicolas J Guehl, Chongzhao Ran, Walter Massefski, Ye Cui, Souheil El-Chemaly, Peter M Sadow, William M Oldham, Marie F Kijewski, Georges El Fakhri, Marc D Normandin, Carmen Priolo. [18F]Fluorocholine and [18F]Fluoroacetate PET as Imaging Biomarkers to Assess Phosphatidylcholine and Mitochondrial Metabolism in Preclinical Models of TSC and LAM.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2018 12; 24(23):5925-5938. doi:
10.1158/1078-0432.ccr-17-3693. [PMID: 30054282] - Mine Araz, Çiğdem Soydal, Elgin Özkan, Metin K Kir, Erkan İbiş, Sevim Güllü, Murat F Erdoğan, Rifat Emral, Özlem N Küçük. The efficacy of fluorine-18-choline PET/CT in comparison with 99mTc-MIBI SPECT/CT in the localization of a hyperfunctioning parathyroid gland in primary hyperparathyroidism.
Nuclear medicine communications.
2018 Nov; 39(11):989-994. doi:
10.1097/mnm.0000000000000899. [PMID: 30138157] - Abdullah A Alharbi, Fahad M Alshehri, Abdulrahman A Albatly, Bert-Ram Sah, Christoph Schmid, Gerhard F Huber, Martin W Huellner. [18F]Fluorocholine Uptake of Parathyroid Adenoma Is Correlated with Parathyroid Hormone Level.
Molecular imaging and biology.
2018 10; 20(5):857-867. doi:
10.1007/s11307-018-1179-x. [PMID: 29508264] - Wouter A M Broos, Maurits Wondergem, Friso M van der Zant, Remco J J Knol. Tertiary Hyperparathyroidism With Renal Osteodystrophy on 18F-Fluorocholine PET/CT.
Clinical nuclear medicine.
2018 Oct; 43(10):766-768. doi:
10.1097/rlu.0000000000002230. [PMID: 30153138] - Mohsen Beheshti, Lukas Hehenwarter, Zeinab Paymani, Gundula Rendl, Larisa Imamovic, Rupert Rettenbacher, Oleksiy Tsybrovskyy, Werner Langsteger, Christian Pirich. 18F-Fluorocholine PET/CT in the assessment of primary hyperparathyroidism compared with 99mTc-MIBI or 99mTc-tetrofosmin SPECT/CT: a prospective dual-centre study in 100 patients.
European journal of nuclear medicine and molecular imaging.
2018 09; 45(10):1762-1771. doi:
10.1007/s00259-018-3980-9. [PMID: 29516131] - Michele Visentin, Angelo Torozi, Zhibo Gai, Stephanie Häusler, Chao Li, Christian Hiller, Peter H Schraml, Holger Moch, Gerd A Kullak-Ublick. Fluorocholine Transport Mediated by the Organic Cation Transporter 2 (OCT2, SLC22A2): Implication for Imaging of Kidney Tumors.
Drug metabolism and disposition: the biological fate of chemicals.
2018 08; 46(8):1129-1136. doi:
10.1124/dmd.118.081091. [PMID: 29794161] - Jiří Ferda, Eva Ferdová, Jan Baxa, Jindřich Fínek, Ondřej Topolčan. 18F-Fluorocholine PET/MRI in Restaging of Prostatic Carcinoma in Relation to PSA Level and Detection of Active Disease.
Anticancer research.
2018 Jul; 38(7):4139-4143. doi:
10.21873/anticanres.12705. [PMID: 29970541] - Marina B Silveira, Daisy M Rodrigues, Marina R Araújo, Michelle A Santiago, Natália T Gonçalves, Brígida G A Schirmer, Márcia M Carneiro, Fernando M Reis, Carlos Malamut, Márcia C Ferreira. 18F-Fluorocholine Uptake and Positron Emission Tomography Imaging in Rat Peritoneal Endometriosis.
Reproductive sciences (Thousand Oaks, Calif.).
2018 01; 25(1):19-25. doi:
10.1177/1933719117728799. [PMID: 28874105] - V Conteduca, E Scarpi, P Caroli, S Salvi, C Lolli, S L Burgio, C Menna, G Schepisi, S Testoni, G Gurioli, G Paganelli, V Casadio, F Matteucci, U De Giorgi. Circulating androgen receptor combined with 18F-fluorocholine PET/CT metabolic activity and outcome to androgen receptor signalling-directed therapies in castration-resistant prostate cancer.
Scientific reports.
2017 Nov; 7(1):15541. doi:
10.1038/s41598-017-15928-y. [PMID: 29138500] - Sandi A Kwee, John Lim, Marc N Coel. Soft Tissue Response on 18F-Fluorocholine PET/CT in Metastatic Castrate-Resistant Prostate Cancer Treated With 223Ra-Dichloride: A Possible Abscopal Effect?.
Clinical nuclear medicine.
2017 Nov; 42(11):868-871. doi:
10.1097/rlu.0000000000001807. [PMID: 28872544] - M Gauthé, O Belissant, A Girard, J Zhang Yin, J Ohnona, A-S Cottereau, V Nataf, S Balogova, D Pontvert, T Lebret, B Guillonneau, O Cussenot, J-N Talbot. [PET/CT and biochemical recurrence of prostate adenocarcinoma: Added value of 68Ga-PSMA-11 when 18F-fluorocholine is non-contributive].
Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie.
2017 Jun; 27(8-9):474-481. doi:
10.1016/j.purol.2017.04.004. [PMID: 28576423] - Aaron Kian Ti Tong, Zoe Xiaozhu Zhang, Sumbul Zaheer, Xuexian Sean Yan. Dual-phase (18)F-fluorocholine PET/CT to detect locoregional recurrence of prostate cancer: comparison between each time point of imaging and a summation scan.
Clinical imaging.
2016 May; 40(3):486-91. doi:
10.1016/j.clinimag.2015.12.010. [PMID: 27133692] - Martin W Huellner, Susanne Aberle, Bert-Ram Sah, Patrick Veit-Haibach, Marco Bonani, Christoph Schmid, Hans Steinert. Visualization of Parathyroid Hyperplasia Using 18F-Fluorocholine PET/MR in a Patient With Secondary Hyperparathyroidism.
Clinical nuclear medicine.
2016 Mar; 41(3):e159-61. doi:
10.1097/rlu.0000000000001053. [PMID: 26462047] - Natalia Arteaga-Marrero, Cecilie Brekke Rygh, Jose F Mainou-Gomez, Tom C H Adamsen, Nataliya Lutay, Rolf K Reed, Dag R Olsen. Radiation treatment monitoring using multimodal functional imaging: PET/CT ((18)F-Fluoromisonidazole & (18)F-Fluorocholine) and DCE-US.
Journal of translational medicine.
2015 Dec; 13(?):383. doi:
10.1186/s12967-015-0708-5. [PMID: 26682742] - Yong-Il Kim, Gi Jeong Cheon, Jin Chul Paeng, Jeong Yeon Cho, Cheol Kwak, Keon Wook Kang, June-Key Chung, Euishin Edmund Kim, Dong Soo Lee. Usefulness of MRI-assisted metabolic volumetric parameters provided by simultaneous (18)F-fluorocholine PET/MRI for primary prostate cancer characterization.
European journal of nuclear medicine and molecular imaging.
2015 Jul; 42(8):1247-56. doi:
10.1007/s00259-015-3026-5. [PMID: 25759164] - Lih Kin Khor, Hoi Yin Loi, Arvind Kumar Sinha, Suat-Jin Lu. Incidental possible diagnosis by 18F-fluorocholine PET/CT of Meckel's diverticulum and potential pitfalls.
Hellenic journal of nuclear medicine.
2015 May; 18(2):157-9. doi:
10.1967/s002449910212. [PMID: 26187217] - Eline E Verwer, Daniela E Oprea-Lager, Alfons J M van den Eertwegh, Reindert J A van Moorselaar, Albert D Windhorst, Lothar A Schwarte, N Harry Hendrikse, Robert C Schuit, Otto S Hoekstra, Adriaan A Lammertsma, Ronald Boellaard. Quantification of 18F-fluorocholine kinetics in patients with prostate cancer.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2015 Mar; 56(3):365-71. doi:
10.2967/jnumed.114.148007. [PMID: 25678491] - Luka Lezaic, Sebastijan Rep, Mojca Jensterle Sever, Tomaz Kocjan, Marko Hocevar, Jure Fettich. ¹⁸F-Fluorocholine PET/CT for localization of hyperfunctioning parathyroid tissue in primary hyperparathyroidism: a pilot study.
European journal of nuclear medicine and molecular imaging.
2014 Nov; 41(11):2083-9. doi:
10.1007/s00259-014-2837-0. [PMID: 25063039] - Sona Balogova, Joseph Ben Zakoun, Laure Michaud, Antoine Khalil, Marc Tassart, Adoracion Esteso, Khaldoun Kerrou, Virginie Huchet, Marie-France Carette, Jean-Pierre Lotz, Jean-Noël Talbot. Whole-body 18F-fluorocholine (FCH) PET/CT and MRI of the spine for monitoring patients with castration-resistant prostate cancer metastatic to bone: a pilot study.
Clinical nuclear medicine.
2014 Nov; 39(11):951-9. doi:
10.1097/rlu.0000000000000562. [PMID: 25140552] - Laetitia Fartoux, Sona Balogova, Valérie Nataf, Khaldoun Kerrou, Virginie Huchet, Olivier Rosmorduc, Jean-Noël Talbot. A pilot comparison of 18F-fluorodeoxyglucose and 18F-fluorocholine PET/CT to predict early recurrence of unifocal hepatocellular carcinoma after surgical resection.
Nuclear medicine communications.
2012 Jul; 33(7):757-65. doi:
10.1097/mnm.0b013e328350fb9f. [PMID: 22504293] - Sandi Kwee, Min-Ae Song, Iona Cheng, Lenora Loo, Maarit Tiirikainen. Measurement of circulating cell-free DNA in relation to 18F-fluorocholine PET/CT imaging in chemotherapy-treated advanced prostate cancer.
Clinical and translational science.
2012 Feb; 5(1):65-70. doi:
10.1111/j.1752-8062.2011.00375.x. [PMID: 22376260] - Sona Balogova, Virginie Huchet, Khaldoun Kerrou, Valerie Nataf, Fabrice Gutman, Martine Antoine, Anne-Marie Ruppert, Aurélie Prignon, Armelle Lavolée, Francoise Montravers, Charles Mayaud, Jacques Cadranel, Jean-Noël Talbot. Detection of bronchioloalveolar cancer by means of PET/CT and 18F-fluorocholine, and comparison with 18F-fluorodeoxyglucose.
Nuclear medicine communications.
2010 May; 31(5):389-97. doi:
10.1097/mnm.0b013e3283369654. [PMID: 20145579] - H Uusijärvi, L-E Nilsson, A Bjartell, S Mattsson. Biokinetics of 18F-choline studied in four prostate cancer patients.
Radiation protection dosimetry.
2010 Apr; 139(1-3):240-4. doi:
10.1093/rpd/ncq024. [PMID: 20150231] - Aditya Bansal, Wang Shuyan, Toshiko Hara, Robert A Harris, Timothy R Degrado. Biodisposition and metabolism of [(18)F]fluorocholine in 9L glioma cells and 9L glioma-bearing fisher rats.
European journal of nuclear medicine and molecular imaging.
2008 Jun; 35(6):1192-203. doi:
10.1007/s00259-008-0736-y. [PMID: 18264706] - Mimoun Nejjari, David Kryza, Gilles Poncet, Colette Roche, Nathalie Perek, Jean-Alain Chayvialle, Didier Le Bars, Jean-Yves Scoazec, Marc Janier, Françoise Borson-Chazot. In vitro and in vivo studies with [(18)F]fluorocholine on digestive tumoral cell lines and in an animal model of metastasized endocrine tumor.
Nuclear medicine and biology.
2008 Jan; 35(1):123-30. doi:
10.1016/j.nucmedbio.2007.09.008. [PMID: 18158951] - Marino Cimitan, Roberto Bortolus, Sandro Morassut, Vincenzo Canzonieri, Antonio Garbeglio, Tanja Baresic, Eugenio Borsatti, Annalisa Drigo, Mauro G Trovò. [18F]fluorocholine PET/CT imaging for the detection of recurrent prostate cancer at PSA relapse: experience in 100 consecutive patients.
European journal of nuclear medicine and molecular imaging.
2006 Dec; 33(12):1387-98. doi:
10.1007/s00259-006-0150-2. [PMID: 16865395] - Jean-Noël Talbot, Fabrice Gutman, Laetitia Fartoux, Jean-Didier Grange, Nathalie Ganne, Khaldoun Kerrou, Dany Grahek, Françoise Montravers, Raoul Poupon, Olivier Rosmorduc. PET/CT in patients with hepatocellular carcinoma using [(18)F]fluorocholine: preliminary comparison with [(18)F]FDG PET/CT.
European journal of nuclear medicine and molecular imaging.
2006 Nov; 33(11):1285-9. doi:
10.1007/s00259-006-0164-9. [PMID: 16802155]
