Indinavir hydrate (BioDeep_00000839980)

   


代谢物信息卡片


Indinavir hydrate

化学式: C36H49N5O5 (631.3733503999999)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)(C)NC(=O)C1CN(CCN1CC(CC(CC2=CC=CC=C2)C(=O)NC3C(CC4=CC=CC=C34)O)O)CC5=CN=CC=C5.O
InChI: /m1./s1

描述信息

D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D000084762 - Viral Protease Inhibitors
D000890 - Anti-Infective Agents > D000998 - Antiviral Agents > D044966 - Anti-Retroviral Agents
C471 - Enzyme Inhibitor > C783 - Protease Inhibitor > C97366 - HIV Protease Inhibitor
C254 - Anti-Infective Agent > C281 - Antiviral Agent > C1660 - Anti-HIV Agent
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors

同义名列表

1 个代谢物同义名

Indinavir hydrate



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Wen-Shan Liu, Han-Gao Li, Chuan-Hua Ding, Hai-Xia Zhang, Rui-Rui Wang, Jia-Qiu Li. Screening potential FDA-approved inhibitors of the SARS-CoV-2 major protease 3CLpro through high-throughput virtual screening and molecular dynamics simulation. Aging. 2021 03; 13(5):6258-6272. doi: 10.18632/aging.202703. [PMID: 33678621]
  • Ana P Costa, Michael H Court, Nicolas F Villarino, Neal S Burke, Katrina L Mealey. Canine orosomucoid (alpha-1 acid glycoprotein) variants and their influence on drug plasma protein binding. Journal of veterinary pharmacology and therapeutics. 2021 Jan; 44(1):116-125. doi: 10.1111/jvp.12899. [PMID: 32744755]
  • Purushothaman Indu, Marimuthu Ragavan Rameshkumar, Narasingam Arunagirinathan, Naif Abdullah Al-Dhabi, Mariadhas Valan Arasu, Savarimuthu Ignacimuthu. Raltegravir, Indinavir, Tipranavir, Dolutegravir, and Etravirine against main protease and RNA-dependent RNA polymerase of SARS-CoV-2: A molecular docking and drug repurposing approach. Journal of infection and public health. 2020 Dec; 13(12):1856-1861. doi: 10.1016/j.jiph.2020.10.015. [PMID: 33168456]
  • Teruhisa S Komatsu, Noriaki Okimoto, Yohei M Koyama, Yoshinori Hirano, Gentaro Morimoto, Yousuke Ohno, Makoto Taiji. Drug binding dynamics of the dimeric SARS-CoV-2 main protease, determined by molecular dynamics simulation. Scientific reports. 2020 10; 10(1):16986. doi: 10.1038/s41598-020-74099-5. [PMID: 33046764]
  • Donald C Hall, Hai-Feng Ji. A search for medications to treat COVID-19 via in silico molecular docking models of the SARS-CoV-2 spike glycoprotein and 3CL protease. Travel medicine and infectious disease. 2020 May; 35(?):101646. doi: 10.1016/j.tmaid.2020.101646. [PMID: 32294562]
  • Masoumeh Kurd, Soroor Sadegh Malvajerd, Saeed Rezaee, Mehrdad Hamidi, Katayoun Derakhshandeh. Oral delivery of indinavir using mPEG-PCL nanoparticles: preparation, optimization, cellular uptake, transport and pharmacokinetic evaluation. Artificial cells, nanomedicine, and biotechnology. 2019 Dec; 47(1):2123-2133. doi: 10.1080/21691401.2019.1616553. [PMID: 31155961]
  • Usisipho Feleni, Unathi Sidwaba, Hlamulo Makelane, Emmanuel Iwuoha. Core-Shell Palladium Telluride Quantum Dot-Hemethiolate Cytochrome Based Biosensor for Detecting Indinavir Drug. Journal of nanoscience and nanotechnology. 2019 12; 19(12):7974-7981. doi: 10.1166/jnn.2019.16866. [PMID: 31196318]
  • Fatma Kalleli, Iness Bettaieb Rebey, Wissem Aidi Wannes, Faycel Boughalleb, Majdi Hammami, Moufida Saidani Tounsi, Mahmoud M'hamdi. Chemical composition and antioxidant potential of essential oil and methanol extract from Tunisian and French fennel (Foeniculum vulgare Mill.) seeds. Journal of food biochemistry. 2019 08; 43(8):e12935. doi: 10.1111/jfbc.12935. [PMID: 31368565]
  • Dan-Dan Tian, Cathrine Leonowens, Emily J Cox, Vanessa González-Pérez, Kosea S Frederick, Yolanda V Scarlett, Michael B Fisher, Mary F Paine. Indinavir Increases Midazolam N-Glucuronidation in Humans: Identification of an Alternate CYP3A Inhibitor Using an In Vitro to In Vivo Approach. Drug metabolism and disposition: the biological fate of chemicals. 2019 07; 47(7):724-731. doi: 10.1124/dmd.119.087007. [PMID: 31028057]
  • Bartłomiej Matłosz, Ewa Pietraszkiewicz, Ewa Firląg-Burkacka, Ewa Grycner, Andrzej Horban, Justyna D Kowalska. Risk factors for kidney disease among HIV-1 positive persons in the methadone program. Clinical and experimental nephrology. 2019 Mar; 23(3):342-348. doi: 10.1007/s10157-018-1644-5. [PMID: 30218298]
  • Mohammad Nasiri, Amir Azadi, Mohammad Reza Saghatchi Zanjani, Mehrdad Hamidi. Indinavir-Loaded Nanostructured Lipid Carriers to Brain Drug Delivery: Optimization, Characterization and Neuropharmacokinetic Evaluation. Current drug delivery. 2019; 16(4):341-354. doi: 10.2174/1567201816666190123124429. [PMID: 30674257]
  • Kaylee Havenga, Efrem Abay, Lubbe Wiesner, Alvaro Viljoen, Dewald Steyn, Josias Hamman. The In Vitro and In Vivo Effects of Hypoxis hemerocallidea on Indinavir Pharmacokinetics: Modulation of Efflux. Planta medica. 2018 Aug; 84(12-13):895-901. doi: 10.1055/a-0607-2743. [PMID: 29672818]
  • Qing Li, Zhi Ye, Peng Zhu, Dong Guo, Hong Yang, Jin Huang, Wei Zhang, James E Polli, Yan Shu. Indinavir Alters the Pharmacokinetics of Lamivudine Partially via Inhibition of Multidrug and Toxin Extrusion Protein 1 (MATE1). Pharmaceutical research. 2018 01; 35(1):14. doi: 10.1007/s11095-017-2290-4. [PMID: 29302757]
  • K Yang, C Battista, J L Woodhead, S H Stahl, J T Mettetal, P B Watkins, S Q Siler, B A Howell. Systems pharmacology modeling of drug-induced hyperbilirubinemia: Differentiating hepatotoxicity and inhibition of enzymes/transporters. Clinical pharmacology and therapeutics. 2017 04; 101(4):501-509. doi: 10.1002/cpt.619. [PMID: 28074467]
  • Candace M Reno, Erwin C Puente, Zhenyu Sheng, Dorit Daphna-Iken, Adam J Bree, Vanessa H Routh, Barbara B Kahn, Simon J Fisher. Brain GLUT4 Knockout Mice Have Impaired Glucose Tolerance, Decreased Insulin Sensitivity, and Impaired Hypoglycemic Counterregulation. Diabetes. 2017 03; 66(3):587-597. doi: 10.2337/db16-0917. [PMID: 27797912]
  • Agnes B Fogo, Mark A Lusco, Behzad Najafian, Charles E Alpers. AJKD Atlas of Renal Pathology: Indinavir Nephrotoxicity. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2017 01; 69(1):e3. doi: 10.1053/j.ajkd.2016.11.004. [PMID: 28007196]
  • Lonette Wallis, Maides Malan, Chrisna Gouws, Dewald Steyn, Suria Ellis, Efrem Abay, Lubbe Wiesner, Daniel P Otto, Josias Hamman. Evaluation of Isolated Fractions of Aloe vera Gel Materials on Indinavir Pharmacokinetics: In vitro and in vivo Studies. Current drug delivery. 2016; 13(3):471-80. doi: 10.2174/1567201813888160302163208. [PMID: 26568138]
  • Carlemi Calitz, Chrisna Gouws, Joe Viljoen, Jan Steenekamp, Lubbe Wiesner, Efrem Abay, Josias Hamman. Herb-Drug Pharmacokinetic Interactions: Transport and Metabolism of Indinavir in the Presence of Selected Herbal Products. Molecules (Basel, Switzerland). 2015 Dec; 20(12):22113-27. doi: 10.3390/molecules201219838. [PMID: 26690396]
  • Z X Lin, C T Che, S S Lee, R C Y Chan, P S P Ip, J M Yang. Sophora flavescens (Ku-Shen) as a booster for antiretroviral therapy through cytochrome P450 3A4 inhibition. Hong Kong medical journal = Xianggang yi xue za zhi. 2015 Dec; 21 Suppl 7(?):S18-21. doi: ". [PMID: 26908268]
  • Yijin Liu, Michael Jann, Chad Vandenberg, Chin B Eap, Shahab A Shamsi. Development of an enantioselective assay for simultaneous separation of venlafaxine and O-desmethylvenlafaxine by micellar electrokinetic chromatography-tandem mass spectrometry: Application to the analysis of drug-drug interaction. Journal of chromatography. A. 2015 Nov; 1420(?):119-28. doi: 10.1016/j.chroma.2015.09.088. [PMID: 26460073]
  • Jennifer P Freeling, Josefin Koehn, Cuiling Shu, Jianguo Sun, Rodney J Y Ho. Anti-HIV drug-combination nanoparticles enhance plasma drug exposure duration as well as triple-drug combination levels in cells within lymph nodes and blood in primates. AIDS research and human retroviruses. 2015 Jan; 31(1):107-14. doi: 10.1089/aid.2014.0210. [PMID: 25402233]
  • Eduardo Milton Ramos-Sanchez, Hiro Goto, Dolores Helena Rodriguez Ferreira Rivero, Thais Mauad, Fernando Nogueira de Souza, Andrea Moreira Monteiro, Magnus Gidlund. In vivo assessment of antiretroviral therapy-associated side effects. Memorias do Instituto Oswaldo Cruz. 2014 Jul; 109(4):484-7. doi: 10.1590/0074-0276130559. [PMID: 25075786]
  • Igbe Ighodaro, Omogbai Kelly Eric, Oyekan Adebayo. Interactions of PPAR α and GLUT4 in DOCA/salt-induced renal injury in mice. Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria. 2013 Dec; 28(2):127-33. doi: . [PMID: 24937386]
  • Jae H Chang, Emile Plise, Jonathan Cheong, Quynh Ho, Molly Lin. Evaluating the in vitro inhibition of UGT1A1, OATP1B1, OATP1B3, MRP2, and BSEP in predicting drug-induced hyperbilirubinemia. Molecular pharmaceutics. 2013 Aug; 10(8):3067-75. doi: 10.1021/mp4001348. [PMID: 23750830]
  • Aaron N Endsley, Rodney J Y Ho. Enhanced anti-HIV efficacy of indinavir after inclusion in CD4-targeted lipid nanoparticles. Journal of acquired immune deficiency syndromes (1999). 2012 Dec; 61(4):417-24. doi: 10.1097/qai.0b013e3182653c1f. [PMID: 22743598]
  • Lisiane Turatti, Eduardo Sprinz, Rosmeri K Lazzaretti, Regina Kuhmmer, Grasiela Agnes, Jussara M Silveira, Rossana P Basso, Cezar A T Pinheiro, Mariângela F Silveira, Silvana de Almeida, Jorge P Ribeiro, Vanessa S Mattevi. Short communication: UGT1A1*28 variant allele is a predictor of severe hyperbilirubinemia in HIV-infected patients on HAART in southern Brazil. AIDS research and human retroviruses. 2012 Sep; 28(9):1015-8. doi: 10.1089/aid.2011.0261. [PMID: 22050734]
  • Tulsi Das Mishra, Hemal Kurani, Puran Singhal, Pranav S Shrivastav. Simultaneous quantitation of HIV-protease inhibitors ritonavir, lopinavir and indinavir in human plasma by UPLC-ESI-MS-MS. Journal of chromatographic science. 2012 Aug; 50(7):625-35. doi: 10.1093/chromsci/bms048. [PMID: 22562821]
  • Fawzia H Toulah, Amal A El-Shafei, Hyat S Al-Rashidi. Evaluation of garlic plant and indinavir drug efficacy in the treatment of cryptosporidiosis in experimentally immumosuppressed rats. Journal of the Egyptian Society of Parasitology. 2012 Aug; 42(2):321-8. doi: 10.12816/0006320. [PMID: 23214211]
  • Michael W Jann, Vicky Spratlin, Kathryn Momary, Hailing Zhang, David Turner, Scott R Penzak, Alan Wright, Chad VanDenBerg. Lack of a pharmacokinetic drug-drug interaction with venlafaxine extended-release/indinavir and desvenlafaxine extended-release/indinavir. European journal of clinical pharmacology. 2012 May; 68(5):715-21. doi: 10.1007/s00228-011-1180-7. [PMID: 22173281]
  • Manish Yadav, Vikas Trivedi, Vivek Upadhyay, Gaurang Shah, Girin A Baxi, Sailendra Goswami, Pranav S Shrivastav. Comparison of extraction procedures for assessment of matrix effect for selective and reliable determination of atazanavir in human plasma by LC-ESI-MS/MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2012 Feb; 885-886(?):138-49. doi: 10.1016/j.jchromb.2011.12.031. [PMID: 22265353]
  • Evan D Kharasch, Pamela Sheffels Bedynek, Christine Hoffer, Alysa Walker, Dale Whittington. Lack of indinavir effects on methadone disposition despite inhibition of hepatic and intestinal cytochrome P4503A (CYP3A). Anesthesiology. 2012 Feb; 116(2):432-47. doi: 10.1097/aln.0b013e3182423478. [PMID: 22273859]
  • Jia-Ming Yang, Siu-Po Ip, Yanfang Xian, Ming Zhao, Zhi-Xiu Lin, John Hok Keung Yeung, Raphael Chiu Yeung Chan, Shui-Shan Lee, Chun-Tao Che. Impact of the herbal medicine Sophora flavescens on the oral pharmacokinetics of indinavir in rats: the involvement of CYP3A and P-glycoprotein. PloS one. 2012; 7(2):e31312. doi: 10.1371/journal.pone.0031312. [PMID: 22359586]
  • Kandadi Prabhakar, Syed Muzammil Afzal, Putcha Uday Kumar, Ajumeera Rajanna, Veerabrahma Kishan. Brain delivery of transferrin coupled indinavir submicron lipid emulsions--pharmacokinetics and tissue distribution. Colloids and surfaces. B, Biointerfaces. 2011 Sep; 86(2):305-13. doi: 10.1016/j.colsurfb.2011.04.013. [PMID: 21565469]
  • Jiangeng Huang, Nagsen Gautam, Sai Praneeth R Bathena, Upal Roy, JoEllyn McMillan, Howard E Gendelman, Yazen Alnouti. UPLC-MS/MS quantification of nanoformulated ritonavir, indinavir, atazanavir, and efavirenz in mouse serum and tissues. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2011 Aug; 879(23):2332-8. doi: 10.1016/j.jchromb.2011.06.032. [PMID: 21752731]
  • Aurélie Barrail-Tran, Anne-Marie Taburet, Jean-Marie Poirier. [Evidence-based therapeutic drug monitoring for indinavir]. Therapie. 2011 May; 66(3):239-46. doi: 10.2515/therapie/2011035. [PMID: 21819808]
  • Vaibhav Dubey, Manoj Nahar, Dinesh Mishra, Pradyumna Mishra, N K Jain. Surface structured liposomes for site specific delivery of an antiviral agent-indinavir. Journal of drug targeting. 2011 May; 19(4):258-69. doi: 10.3109/1061186x.2010.499460. [PMID: 20604740]
  • Prabhakar Kandadi, Muzammil Afzal Syed, Surendar Goparaboina, Kishan Veerabrahma. Brain specific delivery of pegylated indinavir submicron lipid emulsions. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2011 Mar; 42(4):423-32. doi: 10.1016/j.ejps.2011.01.008. [PMID: 21292000]
  • Swetha Bollam, Prabhakar Kandadi, Shashank Sridhar Apte, Kishan Veerabrahma. Development of indinavir submicron lipid emulsions loaded with lipoamino acids-in vivo pharmacokinetics and brain-specific delivery. AAPS PharmSciTech. 2011 Mar; 12(1):422-30. doi: 10.1208/s12249-011-9604-3. [PMID: 21360313]
  • Tim R Cressey, Saik Urien, Deborah Hirt, Guttiga Halue, Malee Techapornroong, Chureeratana Bowonwatanuwong, Prattana Leenasirimakul, Jean-Marc Treluyer, Gonzague Jourdain, Marc Lallemant. Influence of body weight on achieving indinavir concentrations within its therapeutic window in HIV-infected Thai patients receiving indinavir boosted with ritonavir. Therapeutic drug monitoring. 2011 Feb; 33(1):25-31. doi: 10.1097/ftd.0b013e3182057f6f. [PMID: 21233689]
  • Ryan D Cooper, Marcello Tonelli. Renal disease associated with antiretroviral therapy in the treatment of HIV. Nephron. Clinical practice. 2011; 118(3):c262-8. doi: 10.1159/000321646. [PMID: 21212689]
  • Elena Toschi, Cecilia Sgadari, Laura Malavasi, Ilaria Bacigalupo, Chiara Chiozzini, Davide Carlei, Daniela Compagnoni, Stefania Bellino, Roberto Bugarini, Mario Falchi, Clelia Palladino, Patrizia Leone, Giovanni Barillari, Paolo Monini, Barbara Ensoli. Human immunodeficiency virus protease inhibitors reduce the growth of human tumors via a proteasome-independent block of angiogenesis and matrix metalloproteinases. International journal of cancer. 2011 Jan; 128(1):82-93. doi: 10.1002/ijc.25550. [PMID: 20617515]
  • Scott M Hammer, Heather Ribaudo, Roland Bassett, John W Mellors, Lisa M Demeter, Robert W Coombs, Judith Currier, Gene D Morse, John G Gerber, Ana I Martinez, William Spreen, Margaret A Fischl, Kathleen E Squires. A randomized, placebo-controlled trial of abacavir intensification in HIV-1-infected adults with virologic suppression on a protease inhibitor-containing regimen. HIV clinical trials. 2010 Nov; 11(6):312-24. doi: 10.1310/hct1106-312. [PMID: 21239359]
  • Bo Jiang, Alok R Khandelwal, Lynette K Rogers, Valeria Y Hebert, James J Kleinedler, James H Zavecz, Weibin Shi, A Wayne Orr, Tammy R Dugas. Antiretrovirals induce endothelial dysfunction via an oxidant-dependent pathway and promote neointimal hyperplasia. Toxicological sciences : an official journal of the Society of Toxicology. 2010 Oct; 117(2):524-36. doi: 10.1093/toxsci/kfq213. [PMID: 20621964]
  • Fowzia Ibrahim, Claire Naftalin, Emily Cheserem, Jennifer Roe, Lucy J Campbell, Loveleen Bansi, Bruce M Hendry, Caroline Sabin, Frank A Post. Immunodeficiency and renal impairment are risk factors for HIV-associated acute renal failure. AIDS (London, England). 2010 Sep; 24(14):2239-44. doi: 10.1097/qad.0b013e32833c85d6. [PMID: 20634665]
  • Amanda Mocroft, Ole Kirk, Peter Reiss, Stephane De Wit, Dalibor Sedlacek, Marek Beniowski, Jose Gatell, Andrew N Phillips, Bruno Ledergerber, Jens D Lundgren. Estimated glomerular filtration rate, chronic kidney disease and antiretroviral drug use in HIV-positive patients. AIDS (London, England). 2010 Jul; 24(11):1667-78. doi: 10.1097/qad.0b013e328339fe53. [PMID: 20523203]
  • E K Déti, R Thiébaut, F Bonnet, S Lawson-Ayayi, M Dupon, D Neau, J L Pellegrin, D Malvy, S Tchamgoué, F Dabis, P Morlat. Prevalence and factors associated with renal impairment in HIV-infected patients, ANRS C03 Aquitaine Cohort, France. HIV medicine. 2010 May; 11(5):308-17. doi: 10.1111/j.1468-1293.2009.00780.x. [PMID: 20002500]
  • Mehrdad Hamidi. Pharmacokinetic properties of indinavir in rat: some limitations of noncompartmental analysis. Drug development and industrial pharmacy. 2010 Mar; 36(3):355-61. doi: 10.1080/03639040903173564. [PMID: 19722914]
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  • Vanitha Sekar, Eric Lefebvre, Tine De Marez, Martine De Pauw, Els De Paepe, Tony Vangeneugden, Richard M W Hoetelmans. Pharmacokinetic interaction between indinavir and darunavir with low-dose ritonavir in healthy volunteers. Intervirology. 2010; 53(3):176-82. doi: 10.1159/000289341. [PMID: 20197684]
  • Metodi V Stankov, Reinhold E Schmidt, Georg M N Behrens. Impact of stimulatory pathways on adipogenesis and HIV-therapy associated lipoatrophy. Experimental biology and medicine (Maywood, N.J.). 2009 Dec; 234(12):1484-92. doi: 10.3181/0907-rm-205. [PMID: 19934369]
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  • Yunn-Fang Ho, Da-Kong Huang, Wei-Cherng Hsueh, Ming-Yen Lai, Hsiu-Ying Yu, Tung-Hu Tsai. Effects of St. John's wort extract on indinavir pharmacokinetics in rats: differentiation of intestinal and hepatic impacts. Life sciences. 2009 Aug; 85(7-8):296-302. doi: 10.1016/j.lfs.2009.06.008. [PMID: 19559714]
  • L J Campbell, F Ibrahim, M Fisher, S G Holt, B M Hendry, F A Post. Spectrum of chronic kidney disease in HIV-infected patients. HIV medicine. 2009 Jul; 10(6):329-36. doi: 10.1111/j.1468-1293.2008.00691.x. [PMID: 19226409]
  • Bo Jiang, Valeria Y Hebert, Alok R Khandelwal, Karen Y Stokes, Tammy R Dugas. HIV-1 antiretrovirals induce oxidant injury and increase intima-media thickness in an atherogenic mouse model. Toxicology letters. 2009 Jun; 187(3):164-71. doi: 10.1016/j.toxlet.2009.02.017. [PMID: 19429260]
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  • Evan D Kharasch, Christine Hoffer, Dale Whittington, Alysa Walker, Pamela Sheffels Bedynek. Methadone pharmacokinetics are independent of cytochrome P4503A (CYP3A) activity and gastrointestinal drug transport: insights from methadone interactions with ritonavir/indinavir. Anesthesiology. 2009 Mar; 110(3):660-72. doi: 10.1097/aln.0b013e3181986a9a. [PMID: 19225389]
  • Paolo Monini, Cecilia Sgadari, Maria Gabriella Grosso, Stefania Bellino, Antonio Di Biagio, Elena Toschi, Ilaria Bacigalupo, Michela Sabbatucci, Giulia Cencioni, Emanuela Salvi, Patrizia Leone, Barbara Ensoli. Clinical course of classic Kaposi's sarcoma in HIV-negative patients treated with the HIV protease inhibitor indinavir. AIDS (London, England). 2009 Feb; 23(4):534-8. doi: 10.1097/qad.0b013e3283262a8d. [PMID: 19169139]
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  • Guillermo F Bramuglia, Catalina M Cortada, Verónica Curras, Christian Höcht, Fabián Buontempo, Gabriel Mato, Viviana Niselman, Modesto Rubio, Marta Carballo. Relationship between P-glycoprotein activity measured in peripheral blood mononuclear cells and indinavir bioavailability in healthy volunteers. Journal of pharmaceutical sciences. 2009 Jan; 98(1):327-36. doi: 10.1002/jps.21411. [PMID: 18506817]
  • Verónica Curras, Christian Hocht, Andrea Mangano, Viviana Niselman, Eduardo Mariño Hernández, Paulo Cáceres Guido, Débora Mecikovsky, Carolina Bellusci, Rosa Bologna, Luisa Sen, Modesto C Rubio, Guillermo F Bramuglia. Pharmacokinetic study of the variability of indinavir drug levels when boosted with ritonavir in HIV-infected children. Pharmacology. 2009; 83(1):59-66. doi: 10.1159/000178813. [PMID: 19052483]
  • Laure Elens, Sophie Veriter, Vincent Di Fazio, Roger Vanbinst, Daniel Boesmans, Pierre Wallemacq, Vincent Haufroid. Quantification of 8 HIV-protease inhibitors and 2 nonnucleoside reverse transcriptase inhibitors by ultra-performance liquid chromatography with diode array detection. Clinical chemistry. 2009 Jan; 55(1):170-4. doi: 10.1373/clinchem.2008.108647. [PMID: 19028822]
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