Clopidogrel besylate (BioDeep_00000839926)

   


代谢物信息卡片


Clopidogrel besylate

化学式: C22H22ClNO5S2 (479.06278720000006)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC(=O)C(C1=CC=CC=C1Cl)N2CCC3=C(C2)C=CS3.C1=CC=C(C=C1)S(=O)(=O)O
InChI: /m0./s1

描述信息

D018377 - Neurotransmitter Agents > D058905 - Purinergic Agents > D058914 - Purinergic Antagonists
D006401 - Hematologic Agents > D010975 - Platelet Aggregation Inhibitors

同义名列表

1 个代谢物同义名

Clopidogrel besylate



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Hui-Sheng Chen, Yu Cui, Xin-Hong Wang, Yu-Tong Ma, Jing Han, Ying-Jie Duan, Jiang Lu, Li-Ying Shen, Yong Liang, Wei-Zhong Wang, Hui Wang, Yong Zhao, Jin-Tao Zhang, Yu-Lin Song, Xiao-Mei He, Run-Hui Li, Ding-Bo Tao, Jing Li, Shu-Man Huang, Ni Wang, Mei Hong, Chong Meng, Wei Zhang, Duo-Lao Wang, Thanh N Nguyen. Clopidogrel Plus Aspirin vs Aspirin Alone in Patients With Acute Mild to Moderate Stroke: The ATAMIS Randomized Clinical Trial. JAMA neurology. 2024 May; 81(5):450-460. doi: 10.1001/jamaneurol.2024.0146. [PMID: 38466274]
  • Yongkang Zhang, Qingzhi Ran, Kangli Yin, Yinkai Wang, Jiarui Liu, Yuan Zong, Yuzhen Wang, Yemin Cao. The effects of CYP2C19 genotype polymorphism and clopidogrel resistance on ischemic event occurrence in patients with peripheral arterial disease undergoing revascularization: A prospective cohort study. Thrombosis research. 2024 Apr; 236(?):37-50. doi: 10.1016/j.thromres.2024.02.010. [PMID: 38387302]
  • Chayakrit Krittanawong, Johao Escobar, Hafeez Ul Hassan Virk, Mahboob Alam, Salim Virani, Carl J Lavie, K M Venkat Narayan, Raman Sharma. Lifestyle Approach and Medical Therapy of Lower Extremity Peripheral Artery Disease. The American journal of medicine. 2024 Mar; 137(3):202-209. doi: 10.1016/j.amjmed.2023.10.028. [PMID: 37980970]
  • Hongwei Li, Yizhen Fang, Yongquan Chen, Yuning Lin, Zanxi Fang, Zhiyuan Lin, Huabin Xie, Zhongying Zhang. A novel AllGlo probe-quantitative PCR method for detecting single nucleotide polymorphism in CYP2C19 to evaluate the antiplatelet activity of clopidogrel. Scientific reports. 2024 01; 14(1):2358. doi: 10.1038/s41598-024-52540-3. [PMID: 38286794]
  • Ruoyan Yu, Qinglin Yu, Zhenwei Li, Jiyi Li, Jin Yang, Yingchu Hu, Nan Zheng, Xiaojin Li, Yudie Song, Jiahui Li, Xiaomin Chen, Weiping Du, Jia Su. Transcriptome-wide map of N6-methyladenosine (m6A) profiling in coronary artery disease (CAD) with clopidogrel resistance. Clinical epigenetics. 2023 Dec; 15(1):194. doi: 10.1186/s13148-023-01602-w. [PMID: 38098098]
  • Yinxue Guo, Pingyu Ge, Ziju Li, Jingxia Xiao, Lirui Xie. Ticagrelor or Clopidogrel as Antiplatelet Agents in Patients with Chronic Kidney Disease and Cardiovascular Disease: A Meta-analysis. American journal of cardiovascular drugs : drugs, devices, and other interventions. 2023 Sep; 23(5):533-546. doi: 10.1007/s40256-023-00600-w. [PMID: 37530990]
  • Miaohan Qiu, Kun Na, Zizhao Qi, He Zhou, Pengxiao Li, Kai Xu, Bin Wang, Haiwei Liu, Jing Li, Yi Li, Yaling Han. Contemporary Use of Ticagrelor vs Clopidogrel in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: A GRACE Risk Score Stratification-Based Analysis in a Large-Scale, Real-World Study From China. Mayo Clinic proceedings. 2023 Jul; 98(7):1021-1032. doi: 10.1016/j.mayocp.2023.02.004. [PMID: 37419570]
  • Yiting Luo, Yunli Xia, Haonan Zhang, Yunzhu Lin, Lili He, Tao Gong, Zhirong Zhang, Li Deng. Human Serum Albumin-enriched Clopidogrel Bisulfate Nanoparticle Alleviates Cerebral Ischemia-Reperfusion Injury in Rats. Pharmaceutical research. 2023 Jul; 40(7):1821-1833. doi: 10.1007/s11095-023-03543-8. [PMID: 37291463]
  • Hui-Sheng Chen, Yu Cui, Zhong-He Zhou, Hong Zhang, Li-Xia Wang, Wei-Zhong Wang, Li-Ying Shen, Li-Yan Guo, Er-Qiang Wang, Rui-Xian Wang, Jing Han, Yu-Ling Dong, Jing Li, Yong-Zhong Lin, Qing-Cheng Yang, Li Zhang, Jing-Yu Li, Jin Wang, Lei Xia, Guang-Bin Ma, Jiang Lu, Chang-Hao Jiang, Shu-Man Huang, Li-Shu Wan, Xiang-Yu Piao, Zhuo Li, Yan-Song Li, Kui-Hua Yang, Duo-Lao Wang, Thanh N Nguyen. Dual Antiplatelet Therapy vs Alteplase for Patients With Minor Nondisabling Acute Ischemic Stroke: The ARAMIS Randomized Clinical Trial. JAMA. 2023 06; 329(24):2135-2144. doi: 10.1001/jama.2023.7827. [PMID: 37367978]
  • Ziwei Xi, Yong Wang, Qianhong Lu, Hong Qiu, Yanan Gao, Ang Gao, Runlin Gao. Implementation of CYP2C19 genotyping and clinical outcomes following percutaneous coronary intervention in East Asian patients treated with oral P2Y12 inhibitors. Thrombosis research. 2023 May; 228(?):85-93. doi: 10.1016/j.thromres.2023.05.023. [PMID: 37301117]
  • Anxin Wang, Xia Meng, Xue Tian, Yingting Zuo, Philip M Bath, Hao Li, Xuewei Xie, Jing Jing, Jinxi Lin, Yilong Wang, Xingquan Zhao, Liping Liu, Zixiao Li, Yong Jiang, Jie Xu, Feng Wang, Weifeng Chen, Minghua Cao, Jianhua Li, Yongjun Wang. Ticagrelor Aspirin vs Clopidogrel Aspirin in CYP2C19 Loss-of-Function Carriers With Minor Stroke or TIA Stratified by Risk Profile. Neurology. 2023 01; 100(5):e497-e504. doi: 10.1212/wnl.0000000000201454. [PMID: 36535779]
  • Yongkang Zhang, Yuan Zong, Jiarui Liu, Kangli Yin, Yuzhen Wang, Yuefeng Bian, Yichen Huang, Wei Liu, Yemin Cao. Clopidogrel-Related High Residual Platelet Reactivity Associated with Estimated Glomerular Filtration Rate in Patients with Acute Ischemic Stroke. Cerebrovascular diseases extra. 2023; 13(1):83-89. doi: 10.1159/000534466. [PMID: 37812922]
  • Xiao-Wen Yuan, Shi-Yun Yuan, Guo-Xin Wu, Zhi-Xin Wu, Zi-Yun Guan. Genetic polymorphism of clopidogrel metabolism related gene CYP2C19 gene in Chinese from Foshan area of Guangdong Province. Hematology (Amsterdam, Netherlands). 2022 Dec; 27(1):1056-1061. doi: 10.1080/16078454.2022.2121899. [PMID: 36112003]
  • Bangqing Wu, Jiaojiao Yu, Yiting Luo, Lijun Wu, Zhirong Zhang, Li Deng. An Albumin-Enriched Nanocomplex Achieves Systemic Delivery of Clopidogrel Bisulfate to Ameliorate Renal Ischemia Reperfusion Injury in Rats. Molecular pharmaceutics. 2022 11; 19(11):3934-3947. doi: 10.1021/acs.molpharmaceut.2c00401. [PMID: 36067352]
  • Dayong Zheng, Xiao Li, Yang Chu, Yazhuo Li, Dekun Li, Aichun Ju, Yi Wu, Yuesheng Xie, Wei Li. Interaction study of salvianolic acids for injection on pharmacokinetics of clopidogrel in rats using LC-MS/MS. Biomedical chromatography : BMC. 2022 Nov; 36(11):e5463. doi: 10.1002/bmc.5463. [PMID: 35895507]
  • Jiyi Li, Jin Yang, Qinglin Yu, Lian Chen, Xiliang Shi, Jia Su, Keqi Zhu. The DNAm levels of CREB5 (cg11301281) were associated with clopidogrel resistance. Journal of clinical laboratory analysis. 2022 Oct; 36(10):e24690. doi: 10.1002/jcla.24690. [PMID: 36087301]
  • Juan Tamargo, Juan Carlos Kaski, Takeshi Kimura, Jack Charles Barton, Ko Yamamoto, Maki Komiyama, Heinz Drexel, Basil S Lewis, Stefan Agewall, Koji Hasegawa. Racial and ethnic differences in pharmacotherapy to prevent coronary artery disease and thrombotic events. European heart journal. Cardiovascular pharmacotherapy. 2022 Sep; 8(7):738-751. doi: 10.1093/ehjcvp/pvac040. [PMID: 35848895]
  • Manish B Shah. Inhibition of CYP2C8 by Acyl Glucuronides of Gemfibrozil and Clopidogrel: Pharmacological Significance, Progress and Challenges. Biomolecules. 2022 09; 12(9):. doi: 10.3390/biom12091218. [PMID: 36139056]
  • Anxin Wang, Xia Meng, Xue Tian, S Claiborne Johnston, Hao Li, Philip M Bath, Yingting Zuo, Xuewei Xie, Jing Jing, Jinxi Lin, Yilong Wang, Xingquan Zhao, Zixiao Li, Yong Jiang, Liping Liu, Feng Wang, Yanxia Wang, Panbing Huang, Guofang Chen, Yongjun Wang. Effect of Hypertension on Efficacy and Safety of Ticagrelor-Aspirin Versus Clopidogrel-Aspirin in Minor Stroke or Transient Ischemic Attack. Stroke. 2022 09; 53(9):2799-2808. doi: 10.1161/strokeaha.122.038662. [PMID: 35656824]
  • Carol Anne Graham, Mary K Tan, Derek P Chew, Christopher P Gale, Keith A A Fox, Akshay Bagai, Mark A Henderson, Ata Ur Rehman Quraishi, Jean-Pierre Déry, Asim N Cheema, Harold Fisher, David Brieger, Sohrab R Lutchmedial, Shahar Lavi, Brian Y L Wong, Tomas Cieza, Shamir R Mehta, Neil Brass, Shaun G Goodman, Andrew T Yan. Use and outcomes of dual antiplatelet therapy for acute coronary syndrome in patients with chronic kidney disease: insights from the Canadian Observational Antiplatelet Study (COAPT). Heart and vessels. 2022 Aug; 37(8):1291-1298. doi: 10.1007/s00380-022-02029-8. [PMID: 35089380]
  • Xiao-Yan Sheng, Hui-Jie An, Yong-Yang He, Yong-Feng Ye, Jia-Lan Zhao, Sai Li. High-Dose Clopidogrel versus Ticagrelor in CYP2C19 intermediate or poor metabolizers after percutaneous coronary intervention: A Meta-Analysis of Randomized Trials. Journal of clinical pharmacy and therapeutics. 2022 Aug; 47(8):1112-1121. doi: 10.1111/jcpt.13665. [PMID: 35396752]
  • Yuesong Pan, Xia Meng, Aoming Jin, S Claiborne Johnston, Hao Li, Philip M Bath, Xuewei Xie, Jing Jing, Jinxi Lin, Yilong Wang, Xingquan Zhao, Zixiao Li, Yong Jiang, Liping Liu, Hongqin Yang, Jiwei Cheng, Zhimin Wang, Yongjun Wang. Time Course for Benefit and Risk With Ticagrelor and Aspirin in Individuals With Acute Ischemic Stroke or Transient Ischemic Attack Who Carry CYP2C19 Loss-of-Function Alleles: A Secondary Analysis of the CHANCE-2 Randomized Clinical Trial. JAMA neurology. 2022 08; 79(8):739-745. doi: 10.1001/jamaneurol.2022.1457. [PMID: 35727586]
  • Yuesong Pan, Runqi Wangqin, Hao Li, Aoming Jin, Jiejie Li, Jinxi Lin, Xia Meng, Ying Xian, Daniel T Laskowitz, Yongjun Wang. LDL-C levels, lipid-lowering treatment and recurrent stroke in minor ischaemic stroke or TIA. Stroke and vascular neurology. 2022 08; 7(4):276-284. doi: 10.1136/svn-2021-001317. [PMID: 35256525]
  • Cameron D Thomas, Francesco Franchi, Ellen C Keeley, Joseph S Rossi, Marshall Winget, R David Anderson, Alyssa L Dempsey, Yan Gong, Megan N Gower, Richard A Kerensky, Natasha Kulick, Jean G Malave, Caitrin W McDonough, Ian R Mulrenin, Petr Starostik, Amber L Beitelshees, Julie A Johnson, George A Stouffer, Almut G Winterstein, Dominick J Angiolillo, Craig R Lee, Larisa H Cavallari. Impact of the ABCD-GENE Score on Clopidogrel Clinical Effectiveness after PCI: A Multi-Site, Real-World Investigation. Clinical pharmacology and therapeutics. 2022 Jul; 112(1):146-155. doi: 10.1002/cpt.2612. [PMID: 35429163]
  • Yuichi Saito, Takeshi Nishi, Shinichi Wakabayashi, Yuji Ohno, Hideki Kitahara, Noritaka Ariyoshi, Yoshio Kobayashi. Differential Impact of Clinical and Genetic Factors on High Platelet Reactivity in Patients with Coronary Artery Disease Treated with Clopidogrel and Prasugrel. Journal of atherosclerosis and thrombosis. 2022 Jul; 29(7):1031-1039. doi: 10.5551/jat.63035. [PMID: 34234079]
  • Ozkan Ates, Ibrahim Yilmaz, Numan Karaarslan, Emel Ersoz, Fatma Bahar Hacioglu Kasim, Mustafa Dogan, Hanefi Ozbek. Coexistence of SARS-CoV-2 and cerebrovascular diseases: does COVID-19 positivity trigger cerebrovascular pathologies?. Journal of infection in developing countries. 2022 Jun; 16(6):981-992. doi: 10.3855/jidc.15800. [PMID: 35797292]
  • Huihui Lv, Zidong Yang, Haibo Wu, Mingyuan Liu, Xiaowei Mao, Xu Liu, Hongyan Ding, Zhuqing Shi, Yang Zhou, Qianyun Liu, Yongkang Zhang, Yinting Zhou, Kai Chen, Zezhi Li, Qiang Dong, Jianpeng Ma, Yan Han. High On-Treatment Platelet Reactivity as Predictor of Long-term Clinical Outcomes in Stroke Patients with Antiplatelet Agents. Translational stroke research. 2022 06; 13(3):391-398. doi: 10.1007/s12975-021-00949-7. [PMID: 34596891]
  • Tomohiro Higuchi, Mihoko Yamade, Satoru Takahashi, Satoshi Tamura, Shinya Tani, Takuma Kagami, Takahiro Uotani, Yasushi Hamaya, Moriya Iwaizumi, Satoshi Osawa, Ken Sugimoto, Takahisa Furuta. Influence of daily versus alternate-day dosing of vonoprazan on intragastric pH, serum gastrin, and the antiplatelet function of clopidogrel : Influence of alternate-day dosing of vonoprazan. European journal of clinical pharmacology. 2022 Jun; 78(6):955-963. doi: 10.1007/s00228-022-03313-2. [PMID: 35445847]
  • Jean Marie N Mwiza, Robert H Lee, David S Paul, Lori A Holle, Brian C Cooley, Bernhard Nieswandt, Wyatt J Schug, Tomohiro Kawano, Nigel Mackman, Alisa S Wolberg, Wolfgang Bergmeier. Both G protein-coupled and immunoreceptor tyrosine-based activation motif receptors mediate venous thrombosis in mice. Blood. 2022 05; 139(21):3194-3203. doi: 10.1182/blood.2022015787. [PMID: 35358299]
  • S H Verhulst, E Boerrigter, S Ras, N P van Erp, P Hamberg. Unintentional combining enzalutamide with a moderate CYP2C8 inhibitor in a patient with metastatic castration-resistant prostate cancer: a case report. Cancer chemotherapy and pharmacology. 2022 04; 89(4):539-542. doi: 10.1007/s00280-021-04379-y. [PMID: 35059789]
  • Janna K Duong, Romina A Nand, Aarti Patel, Oscar Della Pasqua, Annette S Gross. A physiologically based pharmacokinetic model of clopidogrel in populations of European and Japanese ancestry: An evaluation of CYP2C19 activity. Pharmacology research & perspectives. 2022 04; 10(2):e00946. doi: 10.1002/prp2.946. [PMID: 35307978]
  • Lei Zhang, Zhanhui Li, Yuewen Wu, Yanming Fan, Zhicong He, Peng He, Jingxing Liang. Cinnamon and Aspirin for Mild Ischemic Stroke or Transient Ischemic Attack: A Pilot Trial. Clinical therapeutics. 2022 04; 44(4):482-490. doi: 10.1016/j.clinthera.2022.02.012. [PMID: 35346499]
  • Yan-Jun Lin, Kun-Li Jiao, Bo Liu, Lu Fang, Shu Meng. Antiplatelet and myocardial protective effect of Shexiang Tongxin Dropping Pill in patients undergoing percutaneous coronary intervention: A randomized controlled trial. Journal of integrative medicine. 2022 03; 20(2):126-134. doi: 10.1016/j.joim.2022.01.001. [PMID: 35101369]
  • Fabio Mangiacapra, Luca Paolucci, Michele M Viscusi, Roberto Mangiacapra, Pietro M Ferraro, Annunziata Nusca, Rosetta Melfi, Leonardo De Luca, Domenico Gabrielli, Gian P Ussia, Francesco Grigioni. Prevalence and clinical impact of high platelet reactivity in patients with chronic kidney disease treated with percutaneous coronary intervention: An updated systematic review and meta-analysis. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions. 2022 03; 99(4):1086-1094. doi: 10.1002/ccd.30071. [PMID: 35088526]
  • Anxin Wang, Xia Meng, Xue Tian, S Claiborne Johnston, Hao Li, Philip M Bath, Yingting Zuo, Xuewei Xie, Jing Jing, Jinxi Lin, Yilong Wang, Xingquan Zhao, Zixiao Li, Yong Jiang, Liping Liu, Feng Wang, Ying Li, Jingyao Liu, Yongjun Wang. Bleeding Risk of Dual Antiplatelet Therapy after Minor Stroke or Transient Ischemic Attack. Annals of neurology. 2022 03; 91(3):380-388. doi: 10.1002/ana.26287. [PMID: 34951042]
  • Firas Kobeissy, Khalil Mallah, Kazem Zibara, Fatima Dakroub, Zeinab Dalloul, Mohammad Nasser, Leila Nasrallah, Zahraa Mallah, Ghewa A El-Achkar, Naify Ramadan, Wael Mohamed, Stefania Mondello, Hala Darwish, Eva Hamade, Aida Habib. The effect of clopidogrel and aspirin on the severity of traumatic brain injury in a rat model. Neurochemistry international. 2022 03; 154(?):105301. doi: 10.1016/j.neuint.2022.105301. [PMID: 35121011]
  • Habiba Hussain, Michael D Tarantino, Shruti Chaturvedi, Keith R McCrae, Jonathan C Roberts. Eculizumab for refractory thrombosis in antiphospholipid syndrome. Blood advances. 2022 02; 6(4):1271-1277. doi: 10.1182/bloodadvances.2021005657. [PMID: 35051999]
  • Davide Capodanno, Dominick J Angiolillo, Ryan J Lennon, Shaun G Goodman, Sang-Wook Kim, Fearghas O'Cochlain, Derek Y So, John Sweeney, Charanjit S Rihal, Michael Farkouh, Naveen L Pereira. ABCD-GENE Score and Clinical Outcomes Following Percutaneous Coronary Intervention: Insights from the TAILOR-PCI Trial. Journal of the American Heart Association. 2022 02; 11(4):e024156. doi: 10.1161/jaha.121.024156. [PMID: 35132875]
  • Yannan Pan, Bing Liu, Junmeng Liu, Wei Zhuang, Qing He, Ming Lan. Clopidogrel-induced neutropenia in an 80-year-old patient with chronic kidney disease who underwent percutaneous coronary intervention: a case report and literature review. BMC cardiovascular disorders. 2022 02; 22(1):40. doi: 10.1186/s12872-022-02490-3. [PMID: 35148681]
  • Liye Dai, Jie Xu, Hongyi Yan, Zimo Chen, Yuesong Pan, Xia Meng, Hao Li, Yongjun Wang. Application of Age, Body Mass Index, Chronic Kidney Disease, Diabetes, and Genotyping Score for Efficacy of Clopidogrel: Secondary Analysis of the CHANCE Trial. Stroke. 2022 02; 53(2):465-472. doi: 10.1161/strokeaha.120.033049. [PMID: 34666508]
  • Thomas S Metkus. Searching for the Ideal Antiplatelet Therapy for CABG Patients With Kidney Disease. The Annals of thoracic surgery. 2022 02; 113(2):562. doi: 10.1016/j.athoracsur.2021.04.088. [PMID: 34022214]
  • Pious D Patel, Xinnan Niu, Chevis N Shannon, Joshua C Denny, Josh F Peterson, Matthew R Fusco, Rohan V Chitale. CYP2C19 Loss-of-Function Associated with First-Time Ischemic Stroke in Non-surgical Asymptomatic Carotid Artery Stenosis During Clopidogrel Therapy. Translational stroke research. 2022 02; 13(1):46-55. doi: 10.1007/s12975-021-00896-3. [PMID: 33611730]
  • D-L Wang, X Li, R-N Wang, Y Sun, X-S Xia, W-J Tian, L Wang. A study of microRNA-223 in evaluating platelet reactivity in patients with acute ischemic stroke. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 2022 Feb; 73(1):. doi: 10.26402/jpp.2022.1.11. [PMID: 35793763]
  • Brian Mac Grory, Jonathan P Piccini, Shadi Yaghi, Sven Poli, Adam De Havenon, Sara K Rostanski, Martin Weiss, Ying Xian, S Claiborne Johnston, Wuwei Feng. Hyperglycemia, Risk of Subsequent Stroke, and Efficacy of Dual Antiplatelet Therapy: A Post Hoc Analysis of the POINT Trial. Journal of the American Heart Association. 2022 02; 11(3):e023223. doi: 10.1161/jaha.121.023223. [PMID: 35043692]
  • Jeffrey S Berger, Lucy Z Kornblith, Michelle N Gong, Harmony R Reynolds, Mary Cushman, Yu Cheng, Bryan J McVerry, Keri S Kim, Renato D Lopes, Bassel Atassi, Scott Berry, Grant Bochicchio, Murillo de Oliveira Antunes, Michael E Farkouh, Yonatan Greenstein, Erinn M Hade, Kristin Hudock, Robert Hyzy, Pooja Khatri, Andrei Kindzelski, Bridget-Anne Kirwan, Lisa Baumann Kreuziger, Patrick R Lawler, Eric Leifer, Jose Lopez-Sendon Moreno, Jose Lopez-Sendon, James F Luther, Lilia Nigro Maia, John Quigley, Robert Sherwin, Lana Wahid, Jennifer Wilson, Judith S Hochman, Matthew D Neal. Effect of P2Y12 Inhibitors on Survival Free of Organ Support Among Non-Critically Ill Hospitalized Patients With COVID-19: A Randomized Clinical Trial. JAMA. 2022 01; 327(3):227-236. doi: 10.1001/jama.2021.23605. [PMID: 35040887]
  • Ali Tafazoli, Shreya Anil Kumar, Maha Othman. Thrombocytopathy vs Platelet hyper-reactivity in COVID-19: diverse pathologies, disease outcomes and therapeutic implications. Platelets. 2022 Jan; 33(1):48-53. doi: 10.1080/09537104.2021.1961718. [PMID: 34847829]
  • Abdullah Alkattan, Ahmed Alkhalifah, Eman Alsalameen, Fatimah Alghanim, Nashwa Radwan. Polymorphisms of genes related to phase II metabolism and resistance to clopidogrel. Pharmacogenomics. 2022 01; 23(1):61-79. doi: 10.2217/pgs-2021-0092. [PMID: 34866404]
  • Zahra Lotfollahi, Ana P Q Mello, Francisco A H Fonseca, Luciene O Machado, Andressa F Mathias, Maria C Izar, Nagila R T Damasceno, Cristiano L P Oliveira, Antônio M F Neto. Changes in lipoproteins associated with lipid-lowering and antiplatelet strategies in patients with acute myocardial infarction. PloS one. 2022; 17(8):e0273292. doi: 10.1371/journal.pone.0273292. [PMID: 36040917]
  • Lifang Ma, Zhe Chen, Yan'e Li, Xin Meng, Yongsheng Ma. Clinical Study of Clopidogrel Combined with Huoxue Tongluo Prescription in Improving Transient Ischemic Attack and the Effect on MMP-9, Hcy, and CRP. Journal of healthcare engineering. 2022; 2022(?):6368219. doi: 10.1155/2022/6368219. [PMID: 35399851]
  • Aleksi Tornio, Anne M Filppula, Janne T Backman. Translational aspects of cytochrome P450-mediated drug-drug interactions: A case study with clopidogrel. Basic & clinical pharmacology & toxicology. 2022 Jan; 130 Suppl 1(?):48-59. doi: 10.1111/bcpt.13647. [PMID: 34410044]
  • Xuan Jiang, Fareed Khan, Enyi Shi, Ruixin Fan, Ximing Qian, Hongjia Zhang, Tianxiang Gu. Outcomes of preoperative antiplatelet therapy in patients with acute type A aortic dissection. Journal of cardiac surgery. 2022 Jan; 37(1):53-61. doi: 10.1111/jocs.16080. [PMID: 34657299]
  • Youwen Yang, Zongtao Huang, Xueji Zhang. Efficacy and safety of clopidogrel and/or aspirin for ischemic stroke/transient ischemic attack: An overview of systematic reviews and meta-analysis. Medicine. 2021 Dec; 100(50):e27804. doi: 10.1097/md.0000000000027804. [PMID: 34918630]
  • Hongyu Xu, Qinglin Yu, Honglin Zhou, Jin Yang, Nan Zheng, Zhifeng Xu, Jia Su. Polymorphisms in the GCK gene increase the risk of clopidogrel resistance in stable coronary artery disease (SCAD) patients. Hematology (Amsterdam, Netherlands). 2021 Dec; 26(1):447-452. doi: 10.1080/16078454.2021.1945789. [PMID: 34165031]
  • Yan-Ling Liu, Xiao-Lei Hu, Pei-Yuan Song, He Li, Mu-Peng Li, Yin-Xiao Du, Mo-Yun Li, Qi-Lin Ma, Li-Ming Peng, Ming-Yu Song, Xiao-Ping Chen. Influence of GAS5/MicroRNA-223-3p/P2Y12 Axis on Clopidogrel Response in Coronary Artery Disease. Journal of the American Heart Association. 2021 11; 10(21):e021129. doi: 10.1161/jaha.121.021129. [PMID: 34713722]
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