Senna-lax (BioDeep_00000839865)

   


代谢物信息卡片


Senna-lax

化学式: C42H38O20 (862.1956348000001)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC2=C(C(=C1)OC3C(C(C(C(O3)CO)O)O)O)C(=O)C4=C(C2C5C6=C(C(=CC=C6)OC7C(C(C(C(O7)CO)O)O)O)C(=O)C8=C5C=C(C=C8O)C(=O)O)C=C(C=C4O)C(=O)O
InChI: InChI=1S/C42H38O20/c43-11-23-31(47)35(51)37(53)41(61-23)59-21-5-1-3-15-25(17-7-13(39(55)56)9-19(45)27(17)33(49)29(15)21)26-16-4-2-6-22(60-42-38(54)36(52)32(48)24(12-44)62-42)30(16)34(50)28-18(26)8-14(40(57)58)10-20(28)46/h1-10,23-26,31-32,35-38,41-48,51-54H,11-12H2,(H,55,56)(H,57,58)/t23-,24-,25?,26?,31-,32-,35+,36+,37-,38-,41-,42-/m1/s1

描述信息

D005765 - Gastrointestinal Agents > D054368 - Laxatives

同义名列表

1 个代谢物同义名

Senna-lax



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Khushali Thaker, Jaimini Patoliya, Khushbu Rabadiya, Dhaval Patel, Manivel Ponnuchamy, Nagaraja Reddy Rama Reddy, Rushikesh Joshi. An in-silico approach to unravel the structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase (DAHPS): a critical enzyme for sennoside biosynthesis in Cassia angustifolia Vahl. Journal of biomolecular structure & dynamics. 2024 May; 42(8):3848-3861. doi: 10.1080/07391102.2023.2216300. [PMID: 37243697]
  • Nadja Meier, Beat Meier, Alexander Schenk, Le Nhung Ziegler, Samuel Peter, Evelyn Wolfram. Photostability of sennosides and their aglycones in solution. Phytochemical analysis : PCA. 2024 Jan; ?(?):. doi: 10.1002/pca.3308. [PMID: 38198752]
  • Adrienne B Narrowe, Johanna M S Lemons, Karley K Mahalak, Jenni Firrman, Pieter Van den Abbeele, Aurélien Baudot, Stef Deyaert, Yanfang Li, Liangli Lucy Yu, LinShu Liu. Targeted remodeling of the human gut microbiome using Juemingzi (Senna seed extracts). Frontiers in cellular and infection microbiology. 2024; 14(?):1296619. doi: 10.3389/fcimb.2024.1296619. [PMID: 38638830]
  • Kohei Takagi, Takashi Sugihira, Miho Kitamura, Mami Kawai, Yoko Mitsuguchi, Kosei Tsukamoto, Hirofumi Nakanishi, Toshiaki Makino. Inhibitory effect of Bofutsushosan (Fangfengtongshengsan) extract on the absorption of fructose in rats and mice. Journal of natural medicines. 2023 Apr; ?(?):. doi: 10.1007/s11418-023-01697-8. [PMID: 37040005]
  • Mei-Mei Zhang, Zhi-Cheng Gong, Qi Zhao, Ding-Qiao Xu, Rui-Jia Fu, Yu-Ping Tang, Yan-Yan Chen. Time-dependent laxative effect of sennoside A, the core functional component of rhubarb, is attributed to gut microbiota and aquaporins. Journal of ethnopharmacology. 2023 Mar; ?(?):116431. doi: 10.1016/j.jep.2023.116431. [PMID: 37003403]
  • Rohini Verma, S M Jachak. Isolation and biological evaluation of demethylcassiarin B from Senna siamea Lam. Natural product research. 2023 Jan; ?(?):1-4. doi: 10.1080/14786419.2023.2165075. [PMID: 36630172]
  • Haoua Nacambo, Nerbéwendé Sawadogo, Teyiouê Benoit Joseph Batieno, Mahamadi Hamed Ouedraogo, Abdoul Kader Congo, Wend-Pagnagde Felicien Marie Serge Zida, Kiswendsida Romaric Nanema, Mahamadou Sawadogo. Assessment of Genetic Diversity of a Collection of Senna obtusifolia (L.) Irwin and Barneby Using SSRs Markers in Burkina Faso. TheScientificWorldJournal. 2023; 2023(?):3761799. doi: 10.1155/2023/3761799. [PMID: 37313353]
  • Serhat Sezai Çiçek, Calisto Moreno Cardenas, Ulrich Girreser. Determination of Total Sennosides and Sennosides A, B, and A1 in Senna Leaflets, Pods, and Tablets by Two-Dimensional qNMR. Molecules (Basel, Switzerland). 2022 Oct; 27(21):. doi: 10.3390/molecules27217349. [PMID: 36364175]
  • Jiasi Wu, Yuejia Lan, Xiaoke Shi, Wenge Huang, Sheng Li, Jizhou Zhang, Huan Wang, Fei Wang, Xianli Meng. Sennoside A is a novel inhibitor targeting caspase-1. Food & function. 2022 Oct; 13(19):9782-9795. doi: 10.1039/d2fo01730j. [PMID: 36097956]
  • Qinge Ma, Chong-Zhi Wang, Wamtinga R Sawadogo, Zhao-Xiang Bian, Chun-Su Yuan. Herbal Medicines for Constipation and Phytochemical Comparison of Active Components. The American journal of Chinese medicine. 2022; 50(3):723-732. doi: 10.1142/s0192415x2250029x. [PMID: 35331086]
  • Naila Zaman, Nousheen Parvaiz, Rabia Farid, Afifa Navid, Ghulam Abbas, Syed Sikander Azam. Senna makki and other active phytochemicals: Myths and realities behind covid19 therapeutic interventions. PloS one. 2022; 17(6):e0268454. doi: 10.1371/journal.pone.0268454. [PMID: 35700199]
  • Zhaoyang Wang, Ying Cheng, Wenting Su, Hongxia Zhang, Chu Li, Michael N Routledge, Yunyun Gong, Boling Qiao. Organ Specific Differences in Alteration of Aquaporin Expression in Rats Treated with Sennoside A, Senna Anthraquinones and Rhubarb Anthraquinones. International journal of molecular sciences. 2021 Jul; 22(15):. doi: 10.3390/ijms22158026. [PMID: 34360801]
  • Ying Cheng, Huiqin Zhang, Lejing Qu, Ying He, Michael N Routledge, Yun Yun Gong, Boling Qiao. Identification of rhein as the metabolite responsible for toxicity of rhubarb anthraquinones. Food chemistry. 2020 Nov; 331(?):127363. doi: 10.1016/j.foodchem.2020.127363. [PMID: 32590269]
  • Li Ma, Xinyu Cao, Xiaotong Ye, Youke Qi, Yawen Zhu, Jianping Ye, Yongning Sun. Sennoside A restores colonic barrier function through protecting colon enterocytes from ROS-induced mitochondrial damage in diet-induced obese mice. Biochemical and biophysical research communications. 2020 05; 526(2):519-524. doi: 10.1016/j.bbrc.2020.03.117. [PMID: 32245617]
  • Hongyu Wu, Feng Feng, Xiunan Jiang, Binchuan Hu, Jieying Qiu, CaiHong Wang, Zheng Xiang. Pharmacokinetic and metabolic profiling studies of sennoside B by UPLC-MS/MS and UPLC-Q-TOF-MS. Journal of pharmaceutical and biomedical analysis. 2020 Feb; 179(?):112938. doi: 10.1016/j.jpba.2019.112938. [PMID: 31816471]
  • Xianbin Wang, Ting Wang, Tingting Pan, Mei Huang, Weihua Ren, Geliang Xu, Hatem K Amin, Rami B Kassab, Ahmed E Abdel Moneim. Senna alexandrina extract supplementation reverses hepatic oxidative, inflammatory, and apoptotic effects of cadmium chloride administration in rats. Environmental science and pollution research international. 2020 Feb; 27(6):5981-5992. doi: 10.1007/s11356-019-07117-3. [PMID: 31863371]
  • Zhonghong Wei, Peiliang Shen, Peng Cheng, Yin Lu, Aiyun Wang, Zhiguang Sun. Gut Bacteria Selectively Altered by Sennoside A Alleviate Type 2 Diabetes and Obesity Traits. Oxidative medicine and cellular longevity. 2020; 2020(?):2375676. doi: 10.1155/2020/2375676. [PMID: 32685087]
  • Jurairat Boonruab, Phiyaphon Poonsuk, Watchara Damjuti. Effect of Court-Type Thai Traditional Massage Versus Senokot Treatment on Chronic Constipation: A Randomized Controlled Trial. Journal of evidence-based integrative medicine. 2020 Jan; 25(?):2515690X20960644. doi: 10.1177/2515690x20960644. [PMID: 32993359]
  • Gadah Albasher, Tarfa Albrahim, Nada Aljarba, Raedah I Alharbi, Nouf Alsultan, Jawaher Alsaiari, Humaira Rizwana. Involvement of redox status and the nuclear-related factor 2 in protecting against cadmium-induced renal injury with Sana Makki (Cassia senna L.) pre-treatment in male rats. Anais da Academia Brasileira de Ciencias. 2020; 92(2):e20191237. doi: 10.1590/0001-3765202020191237. [PMID: 32638872]
  • Bukola Christianah Adebayo-Tayo, Samuel O Borode, Olusola Ademola Olaniyi. Phytosynthesis of zinc oxide nanoparticles using methanol extract of Senna alata leaf: Characterization, optimization, antimicrobial properties, and its application in cold cream formulation. Polimery w medycynie. 2020 Jan; 50(1):5-19. doi: 10.17219/pim/122901. [PMID: 32716148]
  • Basiru Olaitan Ajiboye, Oluwafemi Adeleke Ojo, Bamidele Fatoba, Olakunke Bamikole Afolabi, Israel Olayide, Mary Abiola Okesola, Babatunji Emmanuel Oyinloye. In vitro antioxidant and enzyme inhibitory properties of the n-butanol fraction of Senna podocarpa (Guill. and Perr.) leaf. Journal of basic and clinical physiology and pharmacology. 2019 Dec; 31(1):. doi: 10.1515/jbcpp-2019-0123. [PMID: 31874099]
  • Julalak C Ontong, Supakit Paosen, Shiv Shankar, Supayang P Voravuthikunchai. Eco-friendly synthesis of silver nanoparticles using Senna alata bark extract and its antimicrobial mechanism through enhancement of bacterial membrane degradation. Journal of microbiological methods. 2019 10; 165(?):105692. doi: 10.1016/j.mimet.2019.105692. [PMID: 31437555]
  • Mohamed A Farag, Amira S El Senousy, Sherweit H El-Ahmady, Andrea Porzel, Ludger A Wessjohann. Comparative metabolome-based classification of Senna drugs: a prospect for phyto-equivalency of its different commercial products. Metabolomics : Official journal of the Metabolomic Society. 2019 05; 15(5):80. doi: 10.1007/s11306-019-1538-x. [PMID: 31087208]
  • Yixin Cao, Ying He, Cong Wei, Jing Li, Lejing Qu, Huiqin Zhang, Ying Cheng, Boling Qiao. Aquaporins Alteration Profiles Revealed Different Actions of Senna, Sennosides, and Sennoside A in Diarrhea-Rats. International journal of molecular sciences. 2018 Oct; 19(10):. doi: 10.3390/ijms19103210. [PMID: 30336596]
  • Jiamei Le, Weiping Jia, Yongning Sun. Sennoside A protects mitochondrial structure and function to improve high-fat diet-induced hepatic steatosis by targeting VDAC1. Biochemical and biophysical research communications. 2018 06; 500(2):484-489. doi: 10.1016/j.bbrc.2018.04.108. [PMID: 29673597]
  • Zhiqi Yin, Lidan Sun, Qiaomei Jin, Shaoli Song, Yuanbo Feng, Hong Liao, Yicheng Ni, Jian Zhang, Wei Liu. Excretion and toxicity evaluation of 131I-Sennoside A as a necrosis-avid agent. Xenobiotica; the fate of foreign compounds in biological systems. 2017 Nov; 47(11):980-988. doi: 10.1080/00498254.2016.1258740. [PMID: 27830982]
  • Tushar Dhanani, Raghuraj Singh, Nagaraja Reddy, A Trivedi, Satyanshu Kumar. Comparison on extraction yield of sennoside A and sennoside B from senna (Cassia angustifolia) using conventional and non conventional extraction techniques and their quantification using a validated HPLC-PDA detection method. Natural product research. 2017 May; 31(9):1097-1101. doi: 10.1080/14786419.2016.1258562. [PMID: 27855501]
  • Francesca Esposito, Ilaria Carli, Claudia Del Vecchio, Lijia Xu, Angela Corona, Nicole Grandi, Dario Piano, Elias Maccioni, Simona Distinto, Cristina Parolin, Enzo Tramontano. Sennoside A, derived from the traditional chinese medicine plant Rheum L., is a new dual HIV-1 inhibitor effective on HIV-1 replication. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2016 Nov; 23(12):1383-1391. doi: 10.1016/j.phymed.2016.08.001. [PMID: 27765358]
  • Makoto Arai, Yoshinobu Nakada, Kagemasa Kajiwara, Minoru Kimura, Naoaki Ishii. Preparation of Clinically Useful Sennoside-reduced Rhubarb. The Tokai journal of experimental and clinical medicine. 2016 Mar; 41(1):24-9. doi: NULL. [PMID: 27050892]
  • Kento Takayama, Norihiko Tabuchi, Masahito Fukunaga, Nobuyuki Okamura. Rhein 8-O-β-D-Glucopyranoside Elicited the Purgative Action of Daiokanzoto (Da-Huang-Gan-Cao-Tang), Despite Dysbiosis by Ampicillin. Biological & pharmaceutical bulletin. 2016; 39(3):378-83. doi: 10.1248/bpb.b15-00815. [PMID: 26934929]
  • Yeomoon Sim, Hyein Oh, Dal-Seok Oh, Namkwon Kim, Pil Sung Gu, Jin Gyu Choi, Hyo Geun Kim, Tong Ho Kang, Myung Sook Oh. An experimental study on providing a scientific evidence for seven-time alcohol-steaming of Rhei Rhizoma when clinically used. BMC complementary and alternative medicine. 2015 Oct; 15(?):388. doi: 10.1186/s12906-015-0922-y. [PMID: 26506837]
  • Dongjian Zhang, Dejian Huang, Yun Ji, Cuihua Jiang, Yue Li, Meng Gao, Nan Yao, Xuejiao Liu, Haibo Shao, Su Jing, Yicheng Ni, Zhiqi Yin, Jian Zhang. Experimental evaluation of radioiodinated sennoside B as a necrosis-avid tracer agent. Journal of drug targeting. 2015 Feb; 23(2):180-90. doi: 10.3109/1061186x.2014.971328. [PMID: 25330022]
  • Immanuel Rosenthal, Evelyn Wolfram, Beat Meier. An HPLC method to determine sennoside A and sennoside B in Sennae fructus and Sennae folium. Pharmeuropa bio & scientific notes. 2014; 2014(?):92-102. doi: . [PMID: 25655246]
  • Chu VanMen, Yu Seon Jang, Hong Mei Zhu, Jae Hyun Lee, Trinh Nam Trung, Tran Minh Ngoc, Young Ho Kim, Jong Seong Kang. Chemical-based species classification of rhubarb using simultaneous determination of five bioactive substances by HPLC and LDA analysis. Phytochemical analysis : PCA. 2012 Jul; 23(4):359-64. doi: 10.1002/pca.1365. [PMID: 22009582]
  • Huifang Li, Jiabo Wang, Yi Qu, Xiaohe Xiao. [Analysis on changes of purgative biopotency in different processed products of rhubarb]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2012 Feb; 37(3):302-4. doi: ". [PMID: 22568228]
  • Kento Takayama, Hiroyuki Tsutsumi, Takashi Ishizu, Nobuyuki Okamura. The influence of rhein 8-O-β-D-glucopyranoside on the purgative action of sennoside A from rhubarb in mice. Biological & pharmaceutical bulletin. 2012; 35(12):2204-8. doi: 10.1248/bpb.b12-00632. [PMID: 23207772]
  • Manuk N Manukyan, Kerem Tolan, Utku Severge, Wafi Attaallah, Abut Kebudi, Asim Cingi. Prospective randomized comparison of oral sodium phosphate and sennoside A+B calcium lavage for colonoscopy preparation. Surgical laparoscopy, endoscopy & percutaneous techniques. 2011 Apr; 21(2):90-3. doi: 10.1097/sle.0b013e31820e8793. [PMID: 21471799]
  • Jin Gyu Choi, Woong Mo Yang, Tong Ho Kang, Myung Sook Oh. Effects of optimized-SopungSunkiwon on memory impairment and enhancement. Neuroscience letters. 2011 Mar; 491(2):93-8. doi: 10.1016/j.neulet.2010.12.058. [PMID: 21256184]
  • Kento Takayama, Emi Matsui, Takeshi Kobayashi, Hirofumi Inoue, Yasuto Tsuruta, Nobuyuki Okamura. High-performance liquid chromatographic determination and metabolic study of sennoside a in daiokanzoto by mouse intestinal bacteria. Chemical & pharmaceutical bulletin. 2011; 59(9):1106-9. doi: 10.1248/cpb.59.1106. [PMID: 21881253]
  • Emi Matsui, Kento Takayama, Eiji Sato, Nobuyuki Okamura. The influence of glycyrrhiza and antibiotics on the purgative action of sennoside a from Daiokanzoto in mice. Biological & pharmaceutical bulletin. 2011; 34(9):1438-42. doi: 10.1248/bpb.34.1438. [PMID: 21881230]
  • Katsuhiro Yamasaki, Masami Kawaguchi, Takaomi Tagami, Yoshiyuki Sawabe, Satoshi Takatori. Simple and rapid analysis of sennoside A and sennoside B contained in crude drugs and crude drug products by solid-phase extraction and high-performance liquid chromatography. Journal of natural medicines. 2010 Apr; 64(2):126-32. doi: 10.1007/s11418-009-0377-x. [PMID: 20091132]
  • Mitsuko Takahashi, Maki Miyazawa, Katsumi Sakurai, Kenjiro Watabe, Takashi Kojima. [Study on processed senna found in health teas]. Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan. 2009 Dec; 50(6):297-303. doi: 10.3358/shokueishi.50.297. [PMID: 20065619]
  • Osamu Morinaga, Takuhiro Uto, Seiichi Sakamoto, Waraporn Putalun, Sorasak Lhieochaiphant, Hiroyuki Tanaka, Yukihiro Shoyama. Development of eastern blotting technique for sennoside A and sennoside B using anti-sennoside A and anti-sennoside B monoclonal antibodies. Phytochemical analysis : PCA. 2009 Mar; 20(2):154-8. doi: 10.1002/pca.1111. [PMID: 19142851]
  • Osamu Morinaga, Takuhiro Uto, Seiichi Sakamoto, Hiroyuki Tanaka, Yukihiro Shoyama. Enzyme-linked immunosorbent assay for total sennosides using anti-sennside A and anti-sennoside B monoclonal antibodies. Fitoterapia. 2009 Jan; 80(1):28-31. doi: 10.1016/j.fitote.2008.09.004. [PMID: 18926890]
  • B Waltenberger, B Avula, M Ganzera, I A Khan, H Stuppner, S I Khan. Transport of sennosides and sennidines from Cassia angustifolia and Cassia senna across Caco-2 monolayers--an in vitro model for intestinal absorption. Phytomedicine : international journal of phytotherapy and phytopharmacology. 2008 May; 15(5):373-7. doi: 10.1016/j.phymed.2007.03.008. [PMID: 17481875]
  • Qiu-Ping Wu, Zhu-Ju Wang, Li-Ying Tang, Mei-Hong Fu, Yan He, Jing Fang, Qian-Feng Gong. [Determination of five primary chemical constituents in Cassia angustifolia by HPLC]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2008 Feb; 33(4):363-5. doi: ". [PMID: 18533485]
  • Leena Laitinen, Elina Takala, Heikki Vuorela, Pia Vuorela, Ann Marie Kaukonen, Martti Marvola. Anthranoid laxatives influence the absorption of poorly permeable drugs in human intestinal cell culture model (Caco-2). European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 2007 Apr; 66(1):135-45. doi: 10.1016/j.ejpb.2006.09.006. [PMID: 17098405]
  • Jia-kui Wang, Ao Li, Hui Wang, Xiao-yu Xu. [Comparative studies on purgative potency among three spieces of certified rhubarb]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. 2006 Dec; 31(23):1987-91. doi: . [PMID: 17348197]
  • Alpuna Srivastava, Richa Pandey, Ram K Verma, Madan M Gupta. Liquid chromatographic determination of sennosides in Cassia angustifolia leaves. Journal of AOAC International. 2006 Jul; 89(4):937-41. doi: 10.1093/jaoac/89.4.937. [PMID: 16915828]
  • Waraporn Putalun, Suwat Pimmeuangkao, Wanchai De-Eknamkul, Hiroyuki Tanaka, Yukihiro Shoyama. Sennosides A and B production by hairy roots of Senna alata (L.) Roxb. Zeitschrift fur Naturforschung. C, Journal of biosciences. 2006 May; 61(5-6):367-71. doi: 10.1515/znc-2006-5-612. [PMID: 16869495]
  • Soo Bong Choi, Byoung Seob Ko, Seong Kyu Park, Jin Sun Jang, Sunmin Park. Insulin sensitizing and alpha-glucoamylase inhibitory action of sennosides, rheins and rhaponticin in Rhei Rhizoma. Life sciences. 2006 Jan; 78(9):934-42. doi: 10.1016/j.lfs.2005.05.101. [PMID: 16182318]
  • Yasuharu Mizuhara, Yukiho Takizawa, Kazuhisa Ishihara, Takayuki Asano, Hirotaka Kushida, Takashi Morota, Yoshio Kase, Shuichi Takeda, Masaki Aburada, Masaaki Nomura, Koichi Yokogawa. The influence of the sennosides on absorption of glycyrrhetic acid in rats. Biological & pharmaceutical bulletin. 2005 Oct; 28(10):1897-902. doi: 10.1248/bpb.28.1897. [PMID: 16204942]
  • Junko Koyama, Izumi Morita, Hirotaka Fujiyoshi, Norihiro Kobayashi. Simultaneous determination of anthraquinones, their 8-beta-D-glucosides, and sennosides of Rhei Rhizoma by capillary electrophoresis. Chemical & pharmaceutical bulletin. 2005 May; 53(5):573-5. doi: 10.1248/cpb.53.573. [PMID: 15863933]
  • Zhihua Zheng, Chenchen Zhu. [Determination of sennoside A in rhubarb extracts by HPLC]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2004 Dec; 27(12):950-1. doi: ". [PMID: 15807252]
  • Munira Momin, K Pundarikakshudu. In vitro studies on guar gum based formulation for the colon targeted delivery of Sennosides. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques. 2004 Sep; 7(3):325-31. doi: ". [PMID: 15576012]
  • Hiroyuki Tanaka. [Development of rapid and sensitive screening methods for natural products using specific monoclonal antibodies]. Fukuoka igaku zasshi = Hukuoka acta medica. 2004 Aug; 95(8):173-82. doi: ". [PMID: 15552959]
  • Waraporn Putalun, Osamu Morinaga, Hiroyuki Tanaka, Yukihiro Shoyama. Development of a one-step immunochromatographic strip test for the detection of sennosides A and B. Phytochemical analysis : PCA. 2004 Mar; 15(2):112-6. doi: 10.1002/pca.752. [PMID: 15116942]
  • O Morinaga, S Nakajima, H Tanaka, Y Shoyama. Production of monoclonal antibodies against a major purgative component, sennoside B, their characterization and use in ELISA. The Analyst. 2001 Aug; 126(8):1372-6. doi: 10.1039/b103153h. [PMID: 11534608]
  • T Kojima, M Kishi, S Sekita, M Satake. [Origin of sennosides in health teas including Malva leaves]. Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan. 2001 Jun; 42(3):202-5. doi: 10.3358/shokueishi.42.202. [PMID: 11577394]
  • K Tsusumi, S Kishimoto, O Koshitani, H Kohri. Amitriptyline-induced constipation in cynomolgus monkeys is beneficial for the evaluation of laxative efficacy. Biological & pharmaceutical bulletin. 2000 May; 23(5):657-9. doi: 10.1248/bpb.23.657. [PMID: 10823684]
  • S A Shah, M N Ravishankara, A Nirmal, C J Shishoo, I S Rathod, B N Suhagia. Estimation of individual sennosides in plant materials and marketed formulations by an HPTLC method. The Journal of pharmacy and pharmacology. 2000 Apr; 52(4):445-9. doi: 10.1211/0022357001774066. [PMID: 10813557]
  • M Fujiwara, I Okayasu, M Oritsu, J Komatsu, M Yoshitsugu, Y Katoh, T Bandoh, H Toyoshima, Y Kase, K Sugihara, J Kanno, Y Hayashi. Significant increase in prostaglandin E-main urinary metabolite by laxative administration: comparison with ulcerative colitis. Digestion. 2000; 61(3):201-6. doi: 10.1159/000007758. [PMID: 10773726]
  • X Chen, J F Valente, J W Alexander. The effect of sennosides on bacterial translocation and survival in a model of acute hemorrhagic pancreatitis. Pancreas. 1999 Jan; 18(1):39-46. doi: 10.1097/00006676-199901000-00006. [PMID: 9888659]
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