Esomeprazole strontium (BioDeep_00000839859)
代谢物信息卡片
Esomeprazole strontium
化学式: C34H44N6O10S2Sr (848.1616)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=CC(=C3)OC.O.O.O.O.[Sr+2]
InChI: 4*1H2
描述信息
C78276 - Agent Affecting Digestive System or Metabolism > C29701 - Anti-ulcer Agent > C29723 - Proton Pump Inhibitor
D005765 - Gastrointestinal Agents > D000897 - Anti-Ulcer Agents
D004791 - Enzyme Inhibitors > D054328 - Proton Pump Inhibitors
同义名列表
1 个代谢物同义名
数据库引用编号
5 个数据库交叉引用编号
- KEGGdrug: D10120
- PubChem: 16048656
- ChEMBL: CHEMBL2146140
- MeSH: Esomeprazole
- CAS: 934714-36-0
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Qianjun Zhuang, Aijun Liao, Qingling He, Chengxia Liu, Changqing Zheng, Xing Li, Youli Liu, Bangmao Wang, Side Liu, Yan Zhang, Rong Lin, Huixin Chen, Min Deng, Yanping Tang, Chiyi He, Weijie Dai, Haitao Tang, Lei Gong, Liangping Li, Baohong Xu, Changqing Yang, Bingxi Zhou, Dongxing Su, Qinghong Guo, Bin Li, Yongjian Zhou, Xiaoyang Wang, Sujuan Fei, Huili Wu, Sichen Wei, Zhihong Peng, Jianning Wang, Yanqing Li, Hong Wang, Tianwei Deng, Shigang Ding, Fangfang Li, Minhu Chen, Yinglian Xiao. The efficacy and safety of fexuprazan in treating erosive esophagitis: a phase III, randomized, double-blind, multicenter study.
Journal of gastroenterology and hepatology.
2024 Apr; 39(4):658-666. doi:
10.1111/jgh.16471. [PMID: 38251791] - Rozh Q Ameen, Zahra A Amin, Hiwa O Ahmad, Diler D Ghafur, Melodya G Toma, Nyan Sabah, Muhammad Fakhir, Gardoon Abdulla. Gastroprotective effect of rhodanine and 2,4-thiazolidinediones scaffolds in rat stomachs by contribution of anti-apoptotic (BCL-2) and tumor suppressor (P53) proteins.
Scientific reports.
2024 01; 14(1):1699. doi:
10.1038/s41598-024-51446-4. [PMID: 38242960] - Dan-Ni Liu, Qiu-Yan Wang, Pei-Yuan Li, Dong-Han Wu, Jing Pan, Zheng-Yi Chen, Yan-Qiang Li, Xiang-Yang Han, Cheng Lan, Jing Tang, Yan Tan, Cui-Yi Mo, Wei-Zhong Yang, Jun-Ling Han, Xiao-Xi Huang. Comparing high-dose dual therapy with bismuth-containing quadruple therapy for the initial eradication of Helicobacter pylori infection on Hainan Island: A randomized, multicenter clinical trial.
Clinics and research in hepatology and gastroenterology.
2023 05; 47(5):102125. doi:
10.1016/j.clinre.2023.102125. [PMID: 37062356] - Ying-Ying Han, Hui Long, Ya Lin, Qiong He, Wei-Gang Chen, Xiang-Wu Ding, Lin Zhou, Ping An, Fen Wang, Zhen-Yu Zhang, Yun-Lian Hu, Pei-Yuan Li. Optimized dual therapy for treatment-naive patients of Helicobacter pylori infection: A large-scale prospective, multicenter, open-label, randomized controlled study.
Helicobacter.
2022 Oct; 27(5):e12922. doi:
10.1111/hel.12922. [PMID: 35939559] - Imad I Hamdan, Dua'a G H Farah, Enam A Khalil, Randa S H Mansour, Heba Abdel-Halim. Interaction of esomeprazole with insulin detemir and human albumin: A potential cause of hypoglycemia.
Biophysical chemistry.
2022 06; 285(?):106809. doi:
10.1016/j.bpc.2022.106809. [PMID: 35367785] - Leyla Karadurmus, M Emin Corman, Lokman Uzun, Sibel A Ozkan. Enantioselective recognition of esomeprazole with a molecularly imprinted sol-gel-based electrochemical sensor.
Mikrochimica acta.
2022 05; 189(6):225. doi:
10.1007/s00604-022-05321-6. [PMID: 35585299] - Nessreen S Abdelhamid, Maimana A Magdy, Basma H Anwar, Nehal F Farid. US FDA-validated TLC method with four greenness assessment evaluations for simultaneous determination of prednisolone and esomeprazole in spiked human plasma.
Biomedical chromatography : BMC.
2022 May; 36(5):e5343. doi:
10.1002/bmc.5343. [PMID: 35062043] - Jatinder Kaur Mukker, George Dukes, Lisi Wang, Susanna Huh, Polyna Khudyakov, Mitsuhiro Nishihara, Chunlin Chen. Evaluation of the pharmacokinetics of trazpiroben (TAK-906) in the presence and absence of the proton pump inhibitor esomeprazole.
Clinical and translational science.
2022 05; 15(5):1281-1290. doi:
10.1111/cts.13248. [PMID: 35218604] - C Zeng, T Neogi, A T Chan, J Wei, D Misra, N Lu, H K Choi, G Lei, Y Zhang. Proton pump inhibitor therapy and risk of knee replacement surgery: a general population-based cohort study.
Osteoarthritis and cartilage.
2022 04; 30(4):559-569. doi:
10.1016/j.joca.2021.12.010. [PMID: 35031493] - Nehal F Farid, Maimana A Magdy, Basma H Anwar, Nessreen S Abdelhamid. Multivariate Model Update Chemometric Methods for Determination of Prednisolone and Esomeprazole in Spiked Human Plasma: A Comparative Study.
Journal of AOAC International.
2022 Feb; 105(1):317-322. doi:
10.1093/jaoacint/qsab114. [PMID: 34478551] - Ramesh Boinpally, Kaifeng Lu. Evaluation of the Pharmacokinetic Interaction and Safety of Ubrogepant Coadministered With Esomeprazole Magnesium.
Clinical pharmacology in drug development.
2022 02; 11(2):270-277. doi:
10.1002/cpdd.1034. [PMID: 34811955] - Leni van Doorn, Niels Heersche, Femke M de Man, Peter de Bruijn, Ivo Bijl, Esther Oomen-de Hoop, Ferry A L M Eskens, Ate van der Gaast, Ron H J Mathijssen, Sander Bins. Effect of the Proton Pump Inhibitor Esomeprazole on the Systemic Exposure of Capecitabine: Results of A Randomized Crossover Trial.
Clinical pharmacology and therapeutics.
2022 02; 111(2):455-460. doi:
10.1002/cpt.2444. [PMID: 34656072] - Huiping Xu, Melissa O'Gorman, Kyle Matschke, Tanya Boutros, Nicoletta Brega, Weiwei Tan, Akintunde Bello. Evaluation of Proton Pump Inhibitor Esomeprazole on Crizotinib Pharmacokinetics in Healthy Participants.
Clinical pharmacology in drug development.
2022 01; 11(1):34-42. doi:
10.1002/cpdd.1032. [PMID: 34825782] - Camille Lenoir, Amine Niederer, Victoria Rollason, Jules Alexandre Desmeules, Youssef Daali, Caroline Flora Samer. Prediction of cytochromes P450 3A and 2C19 modulation by both inflammation and drug interactions using physiologically based pharmacokinetics.
CPT: pharmacometrics & systems pharmacology.
2022 01; 11(1):30-43. doi:
10.1002/psp4.12730. [PMID: 34791831] - Hae Won Lee, Woo Youl Kang, Wookjae Jung, Mi-Ri Gwon, Kyunghee Cho, Young-Ran Yoon, Sook Jin Seong. Pharmacokinetics and Pharmacodynamics of YYD601, a Dual Delayed-Release Formulation of Esomeprazole, Following Single and Multiple Doses in Healthy Adult Volunteers Under Fasting and Fed Conditions.
Drug design, development and therapy.
2022; 16(?):619-634. doi:
10.2147/dddt.s338131. [PMID: 35281316] - Bahia Abbas Moussa, Hanaa M A Hashem, Marianne Alphonse Mahrouse, Sally Tarek Mahmoud. Synchronized determination of sacubitril and valsartan with some co-administered drugs in human plasma via UPLC-MS/MS method using solid-phase extraction.
Biomedical chromatography : BMC.
2021 Nov; 35(11):e5203. doi:
10.1002/bmc.5203. [PMID: 34145610] - Marouf Alhalabi, Mohammed Waleed Alassi, Kamal Alaa Eddin, Khaled Cheha. Efficacy of two-week therapy with doxycycline-based quadruple regimen versus levofloxacin concomitant regimen for helicobacter pylori infection: a prospective single-center randomized controlled trial.
BMC infectious diseases.
2021 Jul; 21(1):642. doi:
10.1186/s12879-021-06356-5. [PMID: 34218802] - Hólmfríður Helgadóttir, Sigrún H Lund, Sveinbjörn Gizurarson, Helge Waldum, Einar S Björnsson. Pharmacokinetics of single and repeated oral doses of esomeprazole and gastrin elevation in healthy males and females.
Scandinavian journal of gastroenterology.
2021 02; 56(2):128-136. doi:
10.1080/00365521.2020.1859610. [PMID: 33327801] - Yuanhang Yang, Xiaoting Li, Qi Zhou, Lingling Sun, Tianhong Zhang. Simultaneous determination of naproxen and esomeprazole in beagle dog plasma by supercritical fluid chromatography-tandem mass spectrometry coupled with evaporation-free liquid-liquid extraction.
Journal of pharmaceutical and biomedical analysis.
2021 Jan; 193(?):113668. doi:
10.1016/j.jpba.2020.113668. [PMID: 33176242] - Yao Chen, Hongxun Yuan, Hui Ye, Zongming Shi, Xin Deng, Xuezhi Zhang, Xikang Hou. Application of a semi-automatic, intensive follow-up for improving efficacy and adherence of Helicobacter pylori eradication therapy: A randomized controlled trial.
MicrobiologyOpen.
2021 01; 10(1):e1172. doi:
10.1002/mbo3.1172. [PMID: 33650799] - Gang Chen, Li-Juan Ning, Yan Qin, Bin Zhao, Dan Mei, Xue-Mei Li. Acute kidney injury following the use of different proton pump inhibitor regimens: A real-world analysis of post-marketing surveillance data.
Journal of gastroenterology and hepatology.
2021 Jan; 36(1):156-162. doi:
10.1111/jgh.15151. [PMID: 32542684] - Taavi J K Kaartinen, Aleksi Tornio, Tuija Tapaninen, Terhi Launiainen, Nina Isoherranen, Mikko Niemi, Janne T Backman. Effect of High-Dose Esomeprazole on CYP1A2, CYP2C19, and CYP3A4 Activities in Humans: Evidence for Substantial and Long-lasting Inhibition of CYP2C19.
Clinical pharmacology and therapeutics.
2020 12; 108(6):1254-1264. doi:
10.1002/cpt.1949. [PMID: 32558923] - Mario Nagase, Hitoshi Shimada, Masahiro Nii, Shinya Ueda, Mitsuo Higashimori, Katsuomi Ichikawa, Li Zhang, Li Zhou, Yingxue Chen, Diansong Zhou, James Dunyak, Nidal Al-Huniti. Population pharmacokinetic analysis of esomeprazole in Japanese subjects with various CYP2C19 phenotypes.
Journal of clinical pharmacy and therapeutics.
2020 Oct; 45(5):1030-1038. doi:
10.1111/jcpt.13129. [PMID: 32227647] - Doaa El-Bohy, Magdy El Sharkawy, Soheir Abo-Elazm, Sara Shahin, Waleed Bchari, Azza Mancy, Manal El Hamamsy. Esomeprazole vs pantoprazole effects on cyclosporine levels in kidney transplantation: A randomized clinical trial.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.
2020 Oct; 24(5):591-598. doi:
10.1111/1744-9987.13464. [PMID: 31856374] - Jumpei Saito, Naho Yakuwa, Noriko Sandaiji, Hiroyo Kawasaki, Kayoko Kaneko, Tomo Suzuki, Akimasa Yamatani, Haruhiko Sago, Atsuko Murashima. Esomeprazole During Pregnancy and Lactation: Esomeprazole Levels in Maternal Serum, Cord Blood, Breast Milk, and the Infant's Serum.
Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine.
2020 09; 15(9):598-601. doi:
10.1089/bfm.2020.0175. [PMID: 32635742] - Sara Blanco Dorado, Olalla Maroñas Amigo, Ana Latorre-Pellicer, María Teresa Rodríguez Jato, Ana López-Vizcaíno, Aurea Gómez Márquez, Belén Bardán García, Dolores Belles Medall, Gema Barbeito Castiñeiras, María Luisa Pérez Del Molino Bernal, Manuel Campos-Toimil, Francisco Otero Espinar, Andrés Blanco Hortas, Irene Zarra Ferro, Ángel Carracedo, María Jesús Lamas, Anxo Fernández-Ferreiro. A multicentre prospective study evaluating the impact of proton-pump inhibitors omeprazole and pantoprazole on voriconazole plasma concentrations.
British journal of clinical pharmacology.
2020 08; 86(8):1661-1666. doi:
10.1111/bcp.14267. [PMID: 32110830] - Jie Pan, Zhengchao Shi, Dingsai Lin, Ningmin Yang, Fei Meng, Lang Lin, Zhencheng Jin, Qingjie Zhou, Jiansheng Wu, Jianzhong Zhang, Youming Li. Is tailored therapy based on antibiotic susceptibility effective ? a multicenter, open-label, randomized trial.
Frontiers of medicine.
2020 Feb; 14(1):43-50. doi:
10.1007/s11684-019-0706-8. [PMID: 31907860] - Bhuvanachandra Pasupuleti, Vamshikrishna Gone, Ravali Baddam, Raj Kumar Venisetty, Om Prakash Prasad. Clinical Impact of Co-medication of Levetiracetam and Clobazam with Proton Pump Inhibitors: A Drug Interaction Study.
Current drug metabolism.
2020; 21(2):126-131. doi:
10.2174/1389200221666200218121050. [PMID: 32067615] - Zakia Belhadj, Bing He, Jijun Fu, Hua Zhang, Xueqing Wang, Wenbing Dai, Qiang Zhang. Regulating Interactions Between Targeted Nanocarriers and Mononuclear Phagocyte System via an Esomeprazole-Based Preconditioning Strategy.
International journal of nanomedicine.
2020; 15(?):6385-6399. doi:
10.2147/ijn.s258054. [PMID: 32922007] - Manal A Abbas, Yasser I Kandil, Ahmad M Disi, Sahar M Jaffal. Gastroprotective activity of Loranthus acaciae flower extract in a rodent model of ethanol-induced ulcer.
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.
2019 Dec; 44(12):1283-1288. doi:
10.1139/apnm-2019-0166. [PMID: 31009579] - Hongyun Wang, Feng Shao, Xuemei Liu, Wen Xu, Ning Ou, Xianghong Qin, Fang Liu, Xuemei Hou, Haitang Hu, Ji Jiang. Efficacy, safety and pharmacokinetics of ilaprazole infusion in healthy subjects and patients with esomeprazole as positive control.
British journal of clinical pharmacology.
2019 11; 85(11):2547-2558. doi:
10.1111/bcp.14076. [PMID: 31332820] - Amy Fakhry Boushra, Asmaa Mohammed Elsayed, Noha Abdellatif Ibrahim, Maha Khaled Abdelwahed, Eman Ibrahim Ahmed. A comparative study on the possible protective effect of esomeprazole, spirulina, wheatgrass on indomethacin-induced gastric ulcer in male albino rats.
Molecular biology reports.
2019 Oct; 46(5):4843-4860. doi:
10.1007/s11033-019-04933-1. [PMID: 31297714] - Cüneyt Türkeş. A potential risk factor for paraoxonase 1: in silico and in-vitro analysis of the biological activity of proton-pump inhibitors.
The Journal of pharmacy and pharmacology.
2019 Oct; 71(10):1553-1564. doi:
10.1111/jphp.13141. [PMID: 31353473] - Jie Ying, Liu-Cheng Li, Cui-Yun Wu, Zhen-Wei Yu, Lian-Di Kan. The status of proton pump inhibitor use: a prescription survey of 45 hospitals in China.
Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva.
2019 Oct; 111(10):738-743. doi:
10.17235/reed.2019.6155/2019. [PMID: 31373505] - Sungpil Han, Hee Youn Choi, Yo Han Kim, Ji Yeon Nam, Bongtae Kim, Geun Seog Song, Hyeong-Seok Lim, Kyun-Seop Bae. Randomised clinical trial: safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple oral doses of tegoprazan (CJ-12420), a novel potassium-competitive acid blocker, in healthy male subjects.
Alimentary pharmacology & therapeutics.
2019 10; 50(7):751-759. doi:
10.1111/apt.15438. [PMID: 31437865] - Mahmoud M Sebaiy, Wafaa S Hassan, Mostafa E Elhennawy. Developing a High-Performance Liquid Chromatography (HPLC) Method for Simultaneous Determination of Oxytetracycline, Tinidazole and Esomeprazole in Human Plasma.
Journal of chromatographic science.
2019 Aug; 57(8):724-729. doi:
10.1093/chromsci/bmz046. [PMID: 31251331] - Ryohkan Funakoshi, Yukana Tomoda, Toshiyuki Kudo, Kenichi Furihata, Hiroyuki Kusuhara, Kiyomi Ito. Effects of proton pump inhibitors, esomeprazole and vonoprazan, on the disposition of proguanil, a CYP2C19 substrate, in healthy volunteers.
British journal of clinical pharmacology.
2019 07; 85(7):1454-1463. doi:
10.1111/bcp.13914. [PMID: 30845361] - Do-Hyun Seo, Jong-Bok Lee, Ji-Hye Hwang, Jong-Woo Jeong, Gun-Ho Song, Tae-Sung Koo, Kyoung-Won Seo. Pharmacokinetics and pharmacodynamics of intravenous esomeprazole at 2 different dosages in dogs.
Journal of veterinary internal medicine.
2019 Mar; 33(2):531-535. doi:
10.1111/jvim.15383. [PMID: 30548689] - Karen E Hansen, Jeri W Nieves, Sai Nudurupati, David C Metz, Maria Claudia Perez. Dexlansoprazole and Esomeprazole Do Not Affect Bone Homeostasis in Healthy Postmenopausal Women.
Gastroenterology.
2019 03; 156(4):926-934.e6. doi:
10.1053/j.gastro.2018.11.023. [PMID: 30445008] - Dong-Min Yi, Tao-Tao Yang, Shuai-Heng Chao, Ya-Xin Li, Ying-Lei Zhou, Hai-Hui Zhang, Ling Lan, Yu-Wei Zhang, Xue-Mei Wang, Yan-Rui Zhang, Jian Li, Song-Ze Ding. Comparison the cost-efficacy of furazolidone-based versus clarithromycin-based quadruple therapy in initial treatment of Helicobacter pylori infection in a variable clarithromycin drug-resistant region, a single-center, prospective, randomized, open-label study.
Medicine.
2019 Feb; 98(6):e14408. doi:
10.1097/md.0000000000014408. [PMID: 30732192] - Toshiaki Shimizu, Yoshiko Nakayama, Eizaburo Ishii, Shinobu Ida, Tomoki Satou, Daisuke Tokuhara, Katsuhiro Arai, Masahiro Nii, Hans Rydholm, Toshitaka Yajima. Oral esomeprazole in Japanese pediatric patients with gastric acid-related disease: Safety, efficacy, and pharmacokinetics.
Pediatrics international : official journal of the Japan Pediatric Society.
2019 Jan; 61(1):87-95. doi:
10.1111/ped.13733. [PMID: 30422368] - Dasohm Kim, Min Soo Park, Byung Won Yoo, Taegon Hong, Shin Jung Park, Choon Ok Kim. The safety, pharmacodynamics, and pharmacokinetics of immediate-release formulation containing esomeprazole 20 mg/sodium bicarbonate 800 mg in healthy adult male.
Drug design, development and therapy.
2019; 13(?):3151-3159. doi:
10.2147/dddt.s212491. [PMID: 31564831] - Eunwoo Kim, Anhye Kim, Sojeong Yi, Yu Kyong Kim, Seong Bok Jang, Hae Mi Byun, Seo Hyun Yoon, Joo-Youn Cho, In-Jin Jang, Kyung-Sang Yu, SeungHwan Lee. Effect of food on the pharmacokinetics of YH4808, a potassium-competitive acid blocker, after single- and multiple-oral dosing in healthy subjects.
European journal of clinical pharmacology.
2018 Oct; 74(10):1261-1272. doi:
10.1007/s00228-018-2502-9. [PMID: 29907887] - Wangda Zhou, Trevor N Johnson, Khanh H Bui, S Y Amy Cheung, Jianguo Li, Hongmei Xu, Nidal Al-Huniti, Diansong Zhou. Predictive Performance of Physiologically Based Pharmacokinetic (PBPK) Modeling of Drugs Extensively Metabolized by Major Cytochrome P450s in Children.
Clinical pharmacology and therapeutics.
2018 07; 104(1):188-200. doi:
10.1002/cpt.905. [PMID: 29027194] - J Sunwoo, J Oh, S J Moon, S C Ji, S H Lee, K-S Yu, H S Kim, A Lee, I-J Jang. Safety, tolerability, pharmacodynamics and pharmacokinetics of DWP14012, a novel potassium-competitive acid blocker, in healthy male subjects.
Alimentary pharmacology & therapeutics.
2018 07; 48(2):206-218. doi:
10.1111/apt.14818. [PMID: 29863280] - I-Fang Hsin, Shao-Jung Hsu, Chiao-Lin Chuang, Teh-Ia Huo, Hui-Chun Huang, Fa-Yauh Lee, Hsin-Ling Ho, Shu-Yu Chang, Shou-Dong Lee. The effects of proton pump inhibitor on hepatic vascular responsiveness and hemodynamics in cirrhotic rats.
Journal of the Chinese Medical Association : JCMA.
2018 Jul; 81(7):585-592. doi:
10.1016/j.jcma.2018.01.011. [PMID: 29780000] - Amani N Shafik, Mahmoud A Khattab, Ahmed H Osman. Magnesium sulfate versus esomeprazole impact on the neonates of preeclamptic rats.
European journal of obstetrics, gynecology, and reproductive biology.
2018 Jun; 225(?):236-242. doi:
10.1016/j.ejogrb.2018.05.004. [PMID: 29758543] - Tayyar Alp Ozkan, Nihat Karakoyunlu, Reyhan Polat, Gülistan Sanem Sarıbaş, Nevzat Can Şener, Seyda Özdemir, Kevser Peker, Dilek Ünal, Can Tuygun. An evaluation of the protective effect of esomeprazole in an experimental model of renal ischemia-reperfusion.
International urology and nephrology.
2018 Feb; 50(2):217-223. doi:
10.1007/s11255-017-1775-8. [PMID: 29280047] - Hsin Tian, Yanyan Xu, Jiayan Wang, Weiqiang Tian, Jian Sun, Tao Zhang, Qingyun Zhou, Chuxiao Shao. Effects of Plasma Albumin on the Pharmacokinetics of Esomeprazole in ICU Patients.
BioMed research international.
2018; 2018(?):6374374. doi:
10.1155/2018/6374374. [PMID: 30643812] - Jun Nishikawa, Ayumu Hosokawa, Mayo Fuchino, Shunsuke Takatori, Masaya Iwamoto, Yoshiro Kashii, Tadashi Bando, Tetsuro Shimizu, Masami Minemura, Toshiro Sugiyama. [Rhabdomyolysis associated with long-term treatment of esomeprazole].
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology.
2018 ; 115(3):299-304. doi:
10.11405/nisshoshi.115.299. [PMID: 29526982] - Teppei Okamoto, Shingo Hatakeyama, Shogo Hosogoe, Yoshimi Tanaka, Kengo Imanishi, Toru Takashima, Fumitada Saitoh, Tadashi Suzuki, Chikara Ohyama. Proton pump inhibitor as an independent factor of progression of abdominal aortic calcification in patients on maintenance hemodialysis.
PloS one.
2018; 13(7):e0199160. doi:
10.1371/journal.pone.0199160. [PMID: 29969455] - Heba M Eltahir, Maiiada H Nazmy. Esomeprazole ameliorates CCl4 induced liver fibrosis in rats via modulating oxidative stress, inflammatory, fibrogenic and apoptotic markers.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2018 Jan; 97(?):1356-1365. doi:
10.1016/j.biopha.2017.11.028. [PMID: 29156525] - Ran Liu, Pei Li, Jie Xiao, Yidi Yin, Zheng Sun, Kaishun Bi, Qing Li. A fast, sensitive, and high throughput method for the determination of esomeprazole in dog plasma by UHPLC-MS/MS: Application to formulation development of the compound preparation of esomeprazole.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2017 Nov; 1068-1069(?):352-357. doi:
10.1016/j.jchromb.2017.11.002. [PMID: 29128277] - Xiao Ma, Cheng-Wei Tang, Zhi-Yin Huang, Ming-Guang Zhang, Fang Liu, Chun-Hui Wang, Rui Wang, Huan Tong, Ling Liu. [Effect of Proton Pump Inhibitors on Severe Acute Pancreatitis--a Prospective Randomized Trial].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition.
2017 Nov; 48(6):933-936. doi:
NULL. [PMID: 29260533] - S Yi, H Lee, S B Jang, H M Byun, S H Yoon, J-Y Cho, I-J Jang, K-S Yu. A novel K+ competitive acid blocker, YH4808, sustains inhibition of gastric acid secretion with a faster onset than esomeprazole: randomised clinical study in healthy volunteers.
Alimentary pharmacology & therapeutics.
2017 08; 46(3):337-346. doi:
10.1111/apt.14148. [PMID: 28543183] - Ward A Heggermont, Gregor Verhoef, Pieter Evenepoel, Ben Sprangers, Evelyn Lerut, Thomas Tousseyn, Kathleen Claes. Clinical case report: a rare cause of acute kidney failure - tissue is the issue.
Acta clinica Belgica.
2017 Jun; 72(3):201-204. doi:
10.1080/17843286.2016.1178967. [PMID: 27253186] - Wael Talaat. Bioanalytical method for the estimation of co-administered esomeprazole, leflunomide and ibuprofen in human plasma and in pharmaceutical dosage forms using micellar liquid chromatography.
Biomedical chromatography : BMC.
2017 May; 31(5):. doi:
10.1002/bmc.3865. [PMID: 27862093] - J-H Hwang, J-W Jeong, G-H Song, T-S Koo, K-W Seo. Pharmacokinetics and Acid Suppressant Efficacy of Esomeprazole after Intravenous, Oral, and Subcutaneous Administration to Healthy Beagle Dogs.
Journal of veterinary internal medicine.
2017 May; 31(3):743-750. doi:
10.1111/jvim.14713. [PMID: 28407418] - Nazar Muhammad Ranjha, Zermina Rashid, Rabia Razzaq, Hina Raza, Muhammad Hanif, Asif Mahmood. DEVELOPMENT AND VALIDATION OF FAST REVERSED-PHASE HPLC METHOD FOR ANALYSIS OF ESOMEPRAZOLE IN RABBIT PLASMA.
Acta poloniae pharmaceutica.
2017 Mar; 74(2):385-391. doi:
NULL. [PMID: 29624243] - Malcolm Boyce, Frans van den Berg, Toni Mitchell, Kate Darwin, Steve Warrington. Randomised trial of the effect of a gastrin/CCK2 receptor antagonist on esomeprazole-induced hypergastrinaemia: evidence against rebound hyperacidity.
European journal of clinical pharmacology.
2017 Feb; 73(2):129-139. doi:
10.1007/s00228-016-2150-x. [PMID: 27796466] - Marcelo F Montenegro, Michaela L Sundqvist, Filip J Larsen, Zhengbing Zhuge, Mattias Carlström, Eddie Weitzberg, Jon O Lundberg. Blood Pressure-Lowering Effect of Orally Ingested Nitrite Is Abolished by a Proton Pump Inhibitor.
Hypertension (Dallas, Tex. : 1979).
2017 01; 69(1):23-31. doi:
10.1161/hypertensionaha.116.08081. [PMID: 27802417] - Tadashi Shimoyama, Daisuke Chinda, Yoshihiko Sawada, Kazuo Komai, Hironobu Chiba, Yoshiharu Saito, Yoshio Sasaki, Masashi Matsuzaka, Shinsaku Fukuda. Randomized Trial Comparing Esomeprazole and Rabeprazole in First-line Eradication Therapy for Helicobacter pylori Infection based on the Serum Levels of Pepsinogens.
Internal medicine (Tokyo, Japan).
2017; 56(13):1621-1627. doi:
10.2169/internalmedicine.56.7823. [PMID: 28674348] - Christoph Castellani, Georg Singer, Karl Kashofer, Andrea Huber-Zeyringer, Christina Flucher, Margarita Kaiser, Holger Till. The Influence of Proton Pump Inhibitors on the Fecal Microbiome of Infants with Gastroesophageal Reflux-A Prospective Longitudinal Interventional Study.
Frontiers in cellular and infection microbiology.
2017; 7(?):444. doi:
10.3389/fcimb.2017.00444. [PMID: 29075620] - Julie Omolola Okiro, Chaudhry Adeel Ebad, Amjad Zaman Khan. Atypical presentation of anti-GBM nephritis in a 90-year-old patient.
BMJ case reports.
2016 Nov; 2016(?):. doi:
10.1136/bcr-2016-217990. [PMID: 27899391] - Jocelyn Zhou, Michelle Quinlan, Kelli Glenn, Hildegard Boss, Franck Picard, Henry Castro, Dalila Sellami. Effect of esomeprazole, a proton pump inhibitor on the pharmacokinetics of sonidegib in healthy volunteers.
British journal of clinical pharmacology.
2016 10; 82(4):1022-9. doi:
10.1111/bcp.13038. [PMID: 27277189] - Dongyang Liu, Hong Yang, Ji Jiang, Péter Nagy, Kai Shen, Jiaming Qian, Pei Hu. Pharmacokinetic and Pharmacodynamic Modeling Analysis of Intravenous Esomeprazole in Healthy Volunteers.
Journal of clinical pharmacology.
2016 07; 56(7):816-26. doi:
10.1002/jcph.733. [PMID: 26970404] - Dae-Hong Jeon, Yire Kim, Min Jeong Kim, Hyun Seop Cho, Eun Jin Bae, Se-Ho Chang, Dong Jun Park. Rhabdomyolysis associated with single-dose intravenous esomeprazole administration: A case report.
Medicine.
2016 Jul; 95(29):e4313. doi:
10.1097/md.0000000000004313. [PMID: 27442680] - Roelof W F van Leeuwen, Robert Peric, Koen G A M Hussaarts, Emma Kienhuis, Nikki S IJzerman, Peter de Bruijn, Cor van der Leest, Henk Codrington, Jeroen S Kloover, Bronno van der Holt, Joachim G Aerts, Teun van Gelder, Ron H J Mathijssen. Influence of the Acidic Beverage Cola on the Absorption of Erlotinib in Patients With Non-Small-Cell Lung Cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2016 Apr; 34(12):1309-14. doi:
10.1200/jco.2015.65.2560. [PMID: 26858332] - Alessandra Rossi, Luca Castrati, Paolo Colombo, Lisa Flammini, Elisabetta Barocelli, Ruggero Bettini, Lisa Elviri. Development and validation of a DESI-HRMS/MS method for the fast profiling of esomeprazole and its metabolites in rat plasma: a pharmacokinetic study.
Drug testing and analysis.
2016 Feb; 8(2):208-13. doi:
10.1002/dta.1805. [PMID: 25922056] - Elisabeth Angermeier, Katrin Domes, Robert Lukowski, Jens Schlossmann, Birgit Rathkolb, Martin Hraběde Angelis, Franz Hofmann. Iron deficiency anemia in cyclic GMP kinase knockout mice.
Haematologica.
2016 Feb; 101(2):e48-51. doi:
10.3324/haematol.2015.137026. [PMID: 26830212] - Tamehachi Namikoshi, Kazuhiro Harada, Hidekazu Hatta, Takehiko Tokura, Yoshiyuki Oshiro, Tetsuichi Nishizaki, Takahiro Obata, Masahiro Mori, Takaaki Fueki, Sohachi Fujimoto, Yoshisuke Haruna, Atsunori Kuwabara, Daisuke Yorimitsu, Chieko Ihoriya, Hiroyuki Kadoya, Seiji Itano, Yasuo Fujimoto, Norio Komai, Tamaki Sasaki, Naoki Kashihara. Prevalence of gastroesophageal reflux disease symptoms and effects of esomeprazole on the quality of life related to reflux and dyspepsia in patients on maintenance hemodialysis.
Clinical and experimental nephrology.
2016 Feb; 20(1):134-42. doi:
10.1007/s10157-015-1130-2. [PMID: 26026991] - Ayşegül Aksoy Gökmen, Nogay Girginkardeşler, Ali Ahmet Kilimcioğlu, Mümtaz Cem Şirin, Ahmet Özbilgin. [In vitro susceptibility of Trichomonas vaginalis to metronidazole, ornidazole and proton pump inhibitors pantoprazole and esomeprazole].
Mikrobiyoloji bulteni.
2016 Jan; 50(1):133-9. doi:
. [PMID: 27058337] - Shu-Ling Kan, Jing Lu, Jian-Ping Liu, Yi Zhao. Preparation and in vitro/in vivo evaluation of esomeprazole magnesium-modified release pellets.
Drug delivery.
2016; 23(3):866-73. doi:
10.3109/10717544.2014.919545. [PMID: 24892629] - Saheed Sabiu, Taofeeq Garuba, Taofik Olatunde Sunmonu, AbdulHakeem O Sulyman, Nurain O Ismail. Indomethacin-induced gastric ulceration in rats: Ameliorative roles of Spondias mombin and Ficus exasperata.
Pharmaceutical biology.
2016; 54(1):180-6. doi:
10.3109/13880209.2015.1029050. [PMID: 25815713] - Yoshimasa Saito, Hiroshi Serizawa, Yukako Kato, Masaru Nakano, Masahiko Nakamura, Hidetsugu Saito, Hidekazu Suzuki, Takanori Kanai. First-line eradication for Helicobacter pylori-positive gastritis by esomeprazole-based triple therapy is influenced by CYP2C19 genotype.
World journal of gastroenterology.
2015 Dec; 21(48):13548-54. doi:
10.3748/wjg.v21.i48.13548. [PMID: 26730167] - M L Becker, W P J Franken, F Karapinar, R Verzijl-Zeegers, T Schalekamp, R T M van der Hoeven. Possible drug-drug interaction between high-dose esomeprazole and phenprocoumon.
European journal of clinical pharmacology.
2015 Dec; 71(12):1461-5. doi:
10.1007/s00228-015-1912-1. [PMID: 26400679] - Yi Qun Yu, Peter James Whorwell, Lin Heng Wang, Jun Xiang Li, Qing Chang, Jie Meng. Cases Report the Cronkhite-Canada Syndrome: Improving the Prognosis.
Medicine.
2015 Dec; 94(52):e2356. doi:
10.1097/md.0000000000002356. [PMID: 26717374] - Catherine A Cluver, Susan P Walker, Ben W Mol, Gerard B Theron, David R Hall, Richard Hiscock, N Hannan, S Tong. Double blind, randomised, placebo-controlled trial to evaluate the efficacy of esomeprazole to treat early onset pre-eclampsia (PIE Trial): a study protocol.
BMJ open.
2015 Oct; 5(10):e008211. doi:
10.1136/bmjopen-2015-008211. [PMID: 26510725] - Yuan-Pin Hung, Wen-Chien Ko, Po-Han Chou, Yi-Hsuan Chen, Hsiao-Ju Lin, Ya-Hui Liu, Hung-Wen Tsai, Jen-Chieh Lee, Pei-Jane Tsai. Proton-Pump Inhibitor Exposure Aggravates Clostridium difficile-Associated Colitis: Evidence From a Mouse Model.
The Journal of infectious diseases.
2015 Aug; 212(4):654-63. doi:
10.1093/infdis/jiv184. [PMID: 25805751] - Fathalla Belal, Mohie Sharaf El-Din, Manar M Tolba, Heba Alaa. Enhanced spectrofluorimetric determination of esomeprazole and pantoprazole in dosage forms and spiked human plasma using organized media.
Luminescence : the journal of biological and chemical luminescence.
2015 May; 30(3):343-51. doi:
10.1002/bio.2737. [PMID: 25060291] - YoonJung Choi, HyeKyung Han, Dongseong Shin, Kyoung Soo Lim, Kyung-Sang Yu. Comparison of the pharmacokinetics and tolerability of HCP1004 (a fixed-dose combination of naproxen and esomeprazole strontium) and VIMOVO® (a marketed fixed-dose combination of naproxen and esomeprazole magnesium) in healthy volunteers.
Drug design, development and therapy.
2015; 9(?):4127-35. doi:
10.2147/dddt.s86725. [PMID: 26257511] - Hyun-Gyu Choi, Ji-Young Jeon, Seong-Shin Kwak, Hyunil Kim, Changyun Jin, Yong-Jin Im, Eun-Young Kim, Hye Min Wang, Yunjeong Kim, Sun Young Lee, Min-Gul Kim. Pharmacokinetic comparison study of a combination containing 500 mg of Naproxen and 20 mg of Esomeprazole: a randomized, single-dose, 2-way crossover, open-label study in healthy Korean men.
Clinical therapeutics.
2015 Jan; 37(1):83-93. doi:
10.1016/j.clinthera.2014.11.004. [PMID: 25482305] - Nader N Youssef, Eduardo Tron, Vasundhara Tolia, Jennifer E Hamer-Maansson, Per Lundborg, Marta Illueca. Single-dose pharmacokinetic properties of esomeprazole in children aged 1 - 11 years with endoscopically proven GERD: a randomized, open-label study.
International journal of clinical pharmacology and therapeutics.
2014 Nov; 52(11):965-72. doi:
10.5414/cp201971. [PMID: 25250612] - Congwu Huang, Chuan Cen, Xin Ding, Haiyong Zhang, Lingfei Wu. Effects of calcitriol on bone mineral density in patients treated with esomeprazole.
Pharmaceutical biology.
2014 Oct; 52(10):1341-4. doi:
10.3109/13880209.2014.892141. [PMID: 25046547] - J S Shin, J Y Lee, K H Cho, H L Park, M Kukulka, J-T Wu, D Y Kim, S-H Park. The pharmacokinetics, pharmacodynamics and safety of oral doses of ilaprazole 10, 20 and 40 mg and esomeprazole 40 mg in healthy subjects: a randomised, open-label crossover study.
Alimentary pharmacology & therapeutics.
2014 Sep; 40(5):548-61. doi:
10.1111/apt.12860. [PMID: 25041486] - Stephanie A Tse, Rabia S Atayee, Joseph D Ma, Brookie M Best. Factors affecting carisoprodol metabolism in pain patients using urinary excretion data.
Journal of analytical toxicology.
2014 Apr; 38(3):122-8. doi:
10.1093/jat/bku002. [PMID: 24488112] - Samantha Luk, Rabia S Atayee, Joseph D Ma, Brookie M Best. Urinary diazepam metabolite distribution in a chronic pain population.
Journal of analytical toxicology.
2014 Apr; 38(3):135-42. doi:
10.1093/jat/bku001. [PMID: 24500275] - Francesca Perut, Sofia Avnet, Caterina Fotia, Serena Rubina Baglìo, Manuela Salerno, Shigekuni Hosogi, Katsuyuki Kusuzaki, Nicola Baldini. V-ATPase as an effective therapeutic target for sarcomas.
Experimental cell research.
2014 Jan; 320(1):21-32. doi:
10.1016/j.yexcr.2013.10.011. [PMID: 24416789] - Hong Yang, Jingnan Li, Qian Zhao, Ji Li, Kai Shen, Xiaoou Yang, Ji Jiang, Pei Hu, Jiaming Qian. Pharmacokinetics, pharmacodynamics, and safety of esomeprazole injection/infusion in healthy Chinese volunteers: a five-way crossover study.
Journal of gastroenterology and hepatology.
2013 Dec; 28(12):1823-8. doi:
10.1111/jgh.12305. [PMID: 23800161] - Yohannes T Ghebremariam, Paea LePendu, Jerry C Lee, Daniel A Erlanson, Anna Slaviero, Nigam H Shah, James Leiper, John P Cooke. Unexpected effect of proton pump inhibitors: elevation of the cardiovascular risk factor asymmetric dimethylarginine.
Circulation.
2013 Aug; 128(8):845-53. doi:
10.1161/circulationaha.113.003602. [PMID: 23825361] - Shanmugam Gopinath, Ramadass Satiesh Kumar, Madhira Bhawani Shankar, Palanisamy Danabal. Development and validation of a sensitive and high-throughput LC-MS/MS method for the simultaneous determination of esomeprazole and naproxen in human plasma.
Biomedical chromatography : BMC.
2013 Jul; 27(7):894-9. doi:
10.1002/bmc.2878. [PMID: 23483550] - Antoinette R Tan, Darlene G Gibbon, Mark N Stein, Diana Lindquist, Jeffery W Edenfield, Julie C Martin, Charles Gregory, A Benjamin Suttle, Hiroomi Tada, Jeffrey Botbyl, Joseph J Stephenson. Effects of ketoconazole and esomeprazole on the pharmacokinetics of pazopanib in patients with solid tumors.
Cancer chemotherapy and pharmacology.
2013 Jun; 71(6):1635-43. doi:
10.1007/s00280-013-2164-3. [PMID: 23636448] - Lucie Bouchoud, Caroline Fonzo-Christe, Martin Klingmüller, Pascal Bonnabry. Compatibility of intravenous medications with parenteral nutrition: in vitro evaluation.
JPEN. Journal of parenteral and enteral nutrition.
2013 May; 37(3):416-24. doi:
10.1177/0148607112464239. [PMID: 23112277] - Rui-Feng Ding, Yuan-Hu Guo, Wen-Peng Han, Ai-Yu Wang, Li-Ping Xie, Peng-cheng Zhao. [Preventive effects of jinghua weikang capsule on NSAID-induced injury to the mucosa of the small intestine: an experimental research].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2013 Apr; 33(4):522-5. doi:
". [PMID: 23841276] - Dominic-Luc Webb, Tobias Rudholm-Feldreich, Linda Gillberg, Md Abdul Halim, Elvar Theodorsson, Gareth J Sanger, Colin A Campbell, Malcolm Boyce, Erik Näslund, Per M Hellström. The type 2 CCK/gastrin receptor antagonist YF476 acutely prevents NSAID-induced gastric ulceration while increasing iNOS expression.
Naunyn-Schmiedeberg's archives of pharmacology.
2013 Jan; 386(1):41-9. doi:
10.1007/s00210-012-0812-5. [PMID: 23179899] - R Fiocca, L Mastracci, S E Attwood, C Ell, J-P Galmiche, J Hatlebakk, A Bärthel, G Långström, T Lind, L Lundell. Gastric exocrine and endocrine cell morphology under prolonged acid inhibition therapy: results of a 5-year follow-up in the LOTUS trial.
Alimentary pharmacology & therapeutics.
2012 Nov; 36(10):959-71. doi:
10.1111/apt.12052. [PMID: 22998687] - B Medhi, A Prakash, Rupa Joshi, D S Prasad Byrav. Effect of esomeprazole on pharmacokinetics of phenytoin in rabbits.
Indian journal of physiology and pharmacology.
2012 Oct; 56(4):382-7. doi:
. [PMID: 23781659] - Tatyana Zvyaga, Shu-Ying Chang, Cliff Chen, Zheng Yang, Ragini Vuppugalla, Jeremy Hurley, Denise Thorndike, Andrew Wagner, Anjaneya Chimalakonda, A David Rodrigues. Evaluation of six proton pump inhibitors as inhibitors of various human cytochromes P450: focus on cytochrome P450 2C19.
Drug metabolism and disposition: the biological fate of chemicals.
2012 Sep; 40(9):1698-711. doi:
10.1124/dmd.112.045575. [PMID: 22648560] - Marie Sandström, Geoffrey Davidson, Vasundhara Tolia, Janice E Sullivan, Göran Långström, Per Lundborg, Kurt Brown. Phase I, multicenter, randomized, open-label study evaluating the pharmacokinetics and safety profile of repeated once-daily doses of intravenous esomeprazole in children 0 to 17 years of age.
Clinical therapeutics.
2012 Aug; 34(8):1828-38. doi:
10.1016/j.clinthera.2012.06.028. [PMID: 22832034]
