Macimorelin Acetate (BioDeep_00000839839)
代谢物信息卡片
化学式: C28H34N6O5 (534.2590554)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)O.CC(C)(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC3=CNC4=CC=CC=C43)NC=O)N
InChI: /m1./s1
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Clara O Sailer, Bettina Winzeler, Sandrine A Urwyler, Ingeborg Schnyder, Julie Refardt, Anne Eckert, Nimmy Varghese, Martin Fassnacht, Irina Chifu, Elizabeth A Lawson, Joseph G Verbalis, Wiebke Fenske, Mirjam Christ-Crain. Oxytocin levels in response to pituitary provocation tests in healthy volunteers.
European journal of endocrinology.
2021 Aug; 185(3):355-364. doi:
10.1530/eje-21-0346. [PMID: 34181566] - Tobias Lange, Andreas Thomas, Christian Görgens, Martin Bidlingmaier, Katharina Schilbach, Eric Fichant, Philippe Delahaut, Mario Thevis. Comprehensive insights into the formation of metabolites of the ghrelin mimetics capromorelin, macimorelin and tabimorelin as potential markers for doping control purposes.
Biomedical chromatography : BMC.
2021 Jun; 35(6):e5075. doi:
10.1002/bmc.5075. [PMID: 33458843] - Violetta Csákváry, Nicola Ammer, Ekaterine Bakhtadze Bagci, Olena V Bolshova, Birgitte Bentz Damholt, Dragan Katanic, Evgenia Mikhailova, Ágota Muzsnai, Dmitri Raduk, Ganna Senatorova, Mieczysław Szalecki, Michael Teifel, Zsolt Vajda, Nataliya Zelinska, Tetyana Chaychenko. Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Macimorelin in Children with Suspected Growth Hormone Deficiency: An Open-Label, Group Comparison, Dose-Escalation Trial.
Hormone research in paediatrics.
2021; 94(7-8):239-250. doi:
10.1159/000519232. [PMID: 34438400] - Beate Klaus, Richard Sachse, Nicola Ammer, Nicky Kelepouris, Vlady Ostrow. Safety, tolerability, pharmacokinetics, and pharmacodynamics of macimorelin in healthy adults: Results of a single-dose, randomized controlled study.
Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.
2020 06; 52(?):101321. doi:
10.1016/j.ghir.2020.101321. [PMID: 32325373] - M Holubová, A Spolcová, Z Demianová, D Sýkora, J A Fehrentz, J Martinez, A Stofková, J Jurčovičová, J Drápalová, Z Lacinová, M Haluzík, B Zelezná, L Maletínská. Ghrelin agonist JMV 1843 increases food intake, body weight and expression of orexigenic neuropeptides in mice.
Physiological research.
2013; 62(4):435-44. doi:
10.33549/physiolres.932488. [PMID: 23590608] - Carol M MacLean, Anna-Tina Casanova, Luisa Baselgia-Jeker, Nicola Neave, Finn Larsen, Laurence Skillern, Juergen Drewe, Christoph Beglinger. Effect of food on the pharmacokinetics and pharmacodynamics of an oral ghrelin agonist (ARD-07) in healthy subjects.
Journal of clinical pharmacology.
2009 May; 49(5):553-9. doi:
10.1177/0091270008330160. [PMID: 19293342] - Franziska Piccoli, Lukas Degen, Carol MacLean, Shajan Peter, Luisa Baselgia, Finn Larsen, Christoph Beglinger, Jürgen Drewe. Pharmacokinetics and pharmacodynamic effects of an oral ghrelin agonist in healthy subjects.
The Journal of clinical endocrinology and metabolism.
2007 May; 92(5):1814-20. doi:
10.1210/jc.2006-2160. [PMID: 17284637]