Metoclopramide dihydrochloride monohydrate (BioDeep_00000839752)
代谢物信息卡片
化学式: C14H26Cl3N3O3 (389.10396560000004)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCN(CC)CCNC(=O)C1=CC(=C(C=C1OC)N)Cl.O.Cl.Cl
InChI: 1H2
描述信息
D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018492 - Dopamine Antagonists
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents
D005765 - Gastrointestinal Agents > D000932 - Antiemetics
D002491 - Central Nervous System Agents
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Flavia Storelli, Olena Anoshchenko, Jashvant D Unadkat. Successful Prediction of Human Steady-State Unbound Brain-to-Plasma Concentration Ratio of P-gp Substrates Using the Proteomics-Informed Relative Expression Factor Approach.
Clinical pharmacology and therapeutics.
2021 08; 110(2):432-442. doi:
10.1002/cpt.2227
. [PMID: 33675056] - Yifan Chen, Min Zhang, Xinghao Ji, Jinjin Zhao, Shuang Qin, Yinghua Ji, Ruijuan Fan, Yanting Liu, Ping Lu. The anti-cancer effect of metoclopramide on triple-negative breast cancer cells.
Die Pharmazie.
2021 04; 76(4):172-174. doi:
10.1691/ph.2021.0977
. [PMID: 33849703] - Martin Bauer, Sandra Barna, Matthias Blaickner, Konstantin Prosenz, Karsten Bamminger, Verena Pichler, Nicolas Tournier, Marcus Hacker, Markus Zeitlinger, Georgios Karanikas, Oliver Langer. Human Biodistribution and Radiation Dosimetry of the P-Glycoprotein Radiotracer [11C]Metoclopramide.
Molecular imaging and biology.
2021 04; 23(2):180-185. doi:
10.1007/s11307-021-01582-4
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International journal of laboratory hematology.
2021 04; 43(2):e87-e88. doi:
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Clinical pharmacology and therapeutics.
2021 03; 109(3):754-761. doi:
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. [PMID: 32966590] - Irene Hernández-Lozano, Severin Mairinger, Michael Sauberer, Johann Stanek, Thomas Filip, Thomas Wanek, Giuliano Ciarimboli, Nicolas Tournier, Oliver Langer. Influence of Cation Transporters (OCTs and MATEs) on the Renal and Hepatobiliary Disposition of [11C]Metoclopramide in Mice.
Pharmaceutical research.
2021 Jan; 38(1):127-140. doi:
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Archives of pharmacal research.
2020 Nov; 43(11):1207-1213. doi:
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Clinical and translational science.
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BMC pharmacology & toxicology.
2020 01; 21(1):4. doi:
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Materials science & engineering. C, Materials for biological applications.
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Current drug metabolism.
2020; 21(4):301-306. doi:
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Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.
2019 11; 31(11):e13617. doi:
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2019 07; 60(7):985-991. doi:
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World journal of pediatrics : WJP.
2019 Apr; 15(2):135-142. doi:
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International journal of nanomedicine.
2019; 14(?):2383-2395. doi:
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. [PMID: 31040663] - Iram Kaukab, Syed Nisar Hussain Shah, Zelal Kharaba, Ghulam Murtaza, Abubaker Ali Saad, Shakeel Ahmad. Evaluation of Pharmacokinetic Interaction of Cilostazol with Metoclopramide after Oral Administration in Human.
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2019; 20(11):924-928. doi:
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The American journal of emergency medicine.
2018 Jun; 36(6):1124.e1-1124.e2. doi:
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. [PMID: 29534916] - Ying Li, Xianpeng Fan, Wanqing Li, Peng Yang, Hui Zhang, Daoquan Tang, Xiaoxin Yin, Jianxu Sun, Aiping Zheng. Metoclopramide nasal spray in vitro evaluation and in vivo pharmacokinetic studies in dogs.
Pharmaceutical development and technology.
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Theriogenology.
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2018 Feb; 79(2):233-241. doi:
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Cancer biomarkers : section A of Disease markers.
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Anesthesia and analgesia.
2017 01; 124(1):52-60. doi:
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Pakistan journal of pharmaceutical sciences.
2017 Jan; 30(1):143-147. doi:
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Journal of hypertension.
2016 11; 34(11):2258-65. doi:
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Bioanalysis.
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Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2016 Feb; 57(2):309-14. doi:
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Fundamental & clinical pharmacology.
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