Cathine hydrochloride (BioDeep_00000839660)
代谢物信息卡片
Cathine hydrochloride
化学式: C9H14ClNO (187.0763864)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C(C1=CC=CC=C1)O)N.Cl
InChI: /m0./s1
描述信息
D019440 - Anti-Obesity Agents > D001067 - Appetite Depressants
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Hong-Fei Shi, Bo-Peng Xu, Cheng-Xin Xu, Xiu-Qi Zhou, Hong-Fu Xu. [Rapid extraction and detection of five alkaloids in dried khat by solvent extraction-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry].
Se pu = Chinese journal of chromatography.
2023 Sep; 41(9):771-780. doi:
10.3724/sp.j.1123.2023.03009. [PMID: 37712541] - Ahmad M Alamir, Mohammed A Jeraiby, Hesham M Korashy, Emad Sayed Shaheen, Mohammad A Attafi, Magbool E Oraiby, Ahmed M Hakami, Mohammed Y Albeishy, Ibrahim A Khardali, Ismail A Juraybi, Abeer A Alobaida, Ibraheem M Attafi. Cathine and cathinone disposition kinetics and neurotransmitter profile in several organs of rats exposed to a single dose of Catha edulis (Vahl) Forssk. ex Endl. extract.
Drug metabolism and personalized therapy.
2023 Mar; ?(?):. doi:
10.1515/dmpt-2022-0154. [PMID: 36883753] - Sharoen Y M Lim, Jason Siau Ee Loo, Mustafa Alshagga, Mohammed A Alshawsh, Chin E Ong, Yan Pan. Protein-Ligand Identification and In Vitro Inhibitory Effects of Cathine on 11 Major Human Drug Metabolizing Cytochrome P450s.
International journal of toxicology.
2022 Sep; 41(5):355-366. doi:
10.1177/10915818221103790. [PMID: 35658727] - Hsin-Yi Hung, Shih-Min Lin, Chia-Ying Li, Sio-Hong Lam, Yu-Yi Chan, Meei-Jen Liou, Po-Chuen Shieh, Fu-An Chen, Ping-Chung Kuo, Tian-Shung Wu. A Rapid and Feasible 1H-NMR Quantification Method of Ephedrine Alkaloids in Ephedra Herbal Preparations.
Molecules (Basel, Switzerland).
2021 Mar; 26(6):. doi:
10.3390/molecules26061599. [PMID: 33805790] - Elisabeth Pendl, Udo Pauritsch, Manfred Kollroser, Martin G Schmid. Determination of cathinone and cathine in Khat plant material by LC-MS/MS: Fresh vs. dried leaves.
Forensic science international.
2021 Feb; 319(?):110658. doi:
10.1016/j.forsciint.2020.110658. [PMID: 33370655] - Luke R Tembrock, Corey D Broeckling, Adam L Heuberger, Mark P Simmons, Frank R Stermitz, Jessica M Uvarov. Employing Two-stage Derivatisation and GC-MS to Assay for Cathine and Related Stimulant Alkaloids across the Celastraceae.
Phytochemical analysis : PCA.
2017 Jul; 28(4):257-266. doi:
10.1002/pca.2671. [PMID: 28124803] - Eun Sook Jeong, Ki Hun Kim, Eunju Cha, Oh-Seung Kwon, Sangwon Cha, Jaeick Lee. Direct and rapid quantitation of ephedrines in human urine by paper spray ionization/high resolution mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2016 Aug; 1028(?):237-241. doi:
10.1016/j.jchromb.2016.06.040. [PMID: 27393909] - Borbála Molnár, Blanka Fodor, Imre Boldizsár, Ibolya Molnár-Perl. Trimethylsilyl speciations of cathine, cathinone and norephedrine followed by gas chromatography mass spectrometry: Direct sample preparation and analysis of khatamines.
Journal of chromatography. A.
2016 Apr; 1440(?):172-178. doi:
10.1016/j.chroma.2016.02.044. [PMID: 26928873] - J G Pallarés, Á López-Samanes, V E Fernández-Elías, R Aguado-Jiménez, J F Ortega, C Gómez, R Ventura, J Segura, R Mora-Rodríguez. Pseudoephedrine and circadian rhythm interaction on neuromuscular performance.
Scandinavian journal of medicine & science in sports.
2015 Dec; 25(6):e603-12. doi:
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Journal of analytical toxicology.
2015 Jan; 39(1):58-68. doi:
10.1093/jat/bku113. [PMID: 25324527] - Nilesh B Patel. "Natural Amphetamine" Khat: A Cultural Tradition or a Drug of Abuse?.
International review of neurobiology.
2015; 120(?):235-55. doi:
10.1016/bs.irn.2015.02.006. [PMID: 26070760] - Fatma Gurdal, Mahmut Asirdizer, Rezzan Gulhan Aker, Senol Korkut, Yasemin Gocer, E Esra Kucukibrahimoglu, C Haluk Ince. Review of detection frequency and type of synthetic cannabinoids in herbal compounds analyzed by Istanbul Narcotic Department of the Council of Forensic Medicine, Turkey.
Journal of forensic and legal medicine.
2013 Aug; 20(6):667-72. doi:
10.1016/j.jflm.2013.03.041. [PMID: 23910858] - Therese Bredholt, Elisabeth Ersvær, Bjarte Skoe Erikstein, André Sulen, Håkon Reikvam, Hans Jørgen Aarstad, Anne Christine Johannessen, Olav Karsten Vintermyr, Øystein Bruserud, Bjørn Tore Gjertsen. Distinct single cell signal transduction signatures in leukocyte subsets stimulated with khat extract, amphetamine-like cathinone, cathine or norephedrine.
BMC pharmacology & toxicology.
2013 Jul; 14(?):35. doi:
10.1186/2050-6511-14-35. [PMID: 23845085] - Gabriella Roda, Vincenzo Liberti, Sebastiano Arnoldi, Antonella Argo, Chiara Rusconi, Sonia Suardi, Veniero Gambaro. Capillary electrophoretic and extraction conditions for the analysis of Catha edulis FORKS active principles.
Forensic science international.
2013 May; 228(1-3):154-9. doi:
10.1016/j.forsciint.2013.02.034. [PMID: 23597752] - Osquel Barroso, Danielle Goudreault, Marcel-lí Carbó Banús, Christiane Ayotte, Irene Mazzoni, Thierry Boghosian, Olivier Rabin. Determination of urinary concentrations of pseudoephedrine and cathine after therapeutic administration of pseudoephedrine-containing medications to healthy subjects: implications for doping control analysis of these stimulants banned in sport.
Drug testing and analysis.
2012 May; 4(5):320-9. doi:
10.1002/dta.291. [PMID: 21548139] - Veniero Gambaro, Sebastiano Arnoldi, Maria Laura Colombo, Lucia Dell'Acqua, Katia Guerrini, Gabriella Roda. Determination of the active principles of Catha Edulis: quali-quantitative analysis of cathinone, cathine, and phenylpropanolamine.
Forensic science international.
2012 Apr; 217(1-3):87-92. doi:
10.1016/j.forsciint.2011.09.028. [PMID: 22024653] - Saba Kassim, Aamenah Hawash, Atholl Johnston, Ray Croucher. Validation of self-reported khat chewing amongst khat chewers: an exploratory study.
Journal of ethnopharmacology.
2012 Mar; 140(1):193-6. doi:
10.1016/j.jep.2011.12.040. [PMID: 22244798] - Toshiaki Nagai, Akira Kurosu, Kazumi Matsushima, Junko Maeda, Atsushi Tohei, Shinobu Yamauchi, Masahito Hitosugi, Shogo Tokudome. Simultaneous identification of the enantiomers and diastereomers of N,O-di-trifluoroacetylated ephedrine and norephedrine in blood plasma using chiral capillary gas chromatography-mass spectrometry with selected ion monitoring.
Journal of analytical toxicology.
2012 Mar; 36(2):96-105. doi:
10.1093/jat/bkr010. [PMID: 22337778] - Richard Hoffman, Mustafa Al'Absi. Khat use and neurobehavioral functions: suggestions for future studies.
Journal of ethnopharmacology.
2010 Dec; 132(3):554-63. doi:
10.1016/j.jep.2010.05.033. [PMID: 20553832] - Sabina Strano-Rossi, Daniele Leone, Xavier de la Torre, Francesco Botrè. Analysis of stimulants in oral fluid and urine by gas chromatography-mass spectrometry II: pseudophedrine.
Journal of analytical toxicology.
2010 May; 34(4):210-5. doi:
10.1093/jat/34.4.210. [PMID: 20465867] - Tim Laussmann, Sigrid Meier-Giebing. Forensic analysis of hallucinogenic mushrooms and khat (Catha edulis Forsk) using cation-exchange liquid chromatography.
Forensic science international.
2010 Feb; 195(1-3):160-4. doi:
10.1016/j.forsciint.2009.12.013. [PMID: 20047807] - John S Chappell, Marsha M Lee. Cathinone preservation in khat evidence via drying.
Forensic science international.
2010 Feb; 195(1-3):108-20. doi:
10.1016/j.forsciint.2009.12.002. [PMID: 20036789] - Sabina Strano-Rossi, Daniele Leone, Xavier de la Torre, Francesco Botrè. The relevance of the urinary concentration of ephedrines in anti-doping analysis: determination of pseudoephedrine, cathine, and ephedrine after administration of over-the-counter medicaments.
Therapeutic drug monitoring.
2009 Aug; 31(4):520-6. doi:
10.1097/ftd.0b013e3181ac6006. [PMID: 19571776] - A Pokrywka, W Tszyrsznic, D J Kwiatkowska. Problems of the use of pseudoephedrine by athletes.
International journal of sports medicine.
2009 Aug; 30(8):569-72. doi:
10.1055/s-0029-1202826. [PMID: 19382058] - K Deventer, P Van Eenoo, G Baele, O J Pozo, W Van Thuyne, F T Delbeke. Interpretation of urinary concentrations of pseudoephedrine and its metabolite cathine in relation to doping control.
Drug testing and analysis.
2009 May; 1(5):209-13. doi:
10.1002/dta.31. [PMID: 20355197] - Kuei Hui Chan, Mei-Chich Hsu, Fu-An Chen, Ku-Fu Hsu. Elimination of ephedrines in urine following administration of a Sho-seiryu-to preparation.
Journal of analytical toxicology.
2009 Apr; 33(3):162-6. doi:
10.1093/jat/33.3.162. [PMID: 19371465] - Hesham Abdul Aziz, Kok Khiang Peh, Yvonne Tze Fung Tan. Extraction and microencapsulation of khat: effects on sexual motivation and estradiol level in female rats.
The journal of sexual medicine.
2009 Mar; 6(3):682-95. doi:
10.1111/j.1743-6109.2008.01157.x. [PMID: 19143913] - Raz Krizevski, Nativ Dudai, Einat Bar, Efraim Lewinsohn. Developmental patterns of phenylpropylamino alkaloids accumulation in khat (Catha edulis, Forsk.).
Journal of ethnopharmacology.
2007 Dec; 114(3):432-8. doi:
10.1016/j.jep.2007.08.042. [PMID: 17928181] - P Van Eenoo, L Lootens, A Spaerkeer, W Van Thuyne, K Deventer, F T Delbeke. Results of stability studies with doping agents in urine.
Journal of analytical toxicology.
2007 Nov; 31(9):543-8. doi:
10.1093/jat/31.9.543. [PMID: 18093412] - E Oyungu, P G Kioy, N B Patel. Effect of Catha edulis (khat) on behaviour and its potential to induce seizures in Sprague Dawley rats.
East African medical journal.
2007 May; 84(5):219-25. doi:
10.4314/eamj.v84i5.9529. [PMID: 17892196] - Kuei Hui Chan, Ryh-Nan Pan, Mei-Chich Hsu. Simultaneous quantification of six ephedrines in a Mahwang preparation and in urine by high-performance liquid chromatography.
Biomedical chromatography : BMC.
2005 Jun; 19(5):337-42. doi:
10.1002/bmc.452. [PMID: 15931652] - William A Trujillo, Wendy R Sorenson. Determination of ephedrine alkaloids in human urine and plasma by liquid chromatography/tandem mass spectrometry: collaborative study.
Journal of AOAC International.
2003 Jul; 86(4):643-56. doi:
. [PMID: 14509420] - Stefan W Toennes, Sebastian Harder, Markus Schramm, Constanze Niess, Gerold F Kauert. Pharmacokinetics of cathinone, cathine and norephedrine after the chewing of khat leaves.
British journal of clinical pharmacology.
2003 Jul; 56(1):125-30. doi:
10.1046/j.1365-2125.2003.01834.x. [PMID: 12848785] - Frank Sporkert, Fritz Pragst, Rainer Bachus, Florian Masuhr, Lutz Harms. Determination of cathinone, cathine and norephedrine in hair of Yemenite khat chewers.
Forensic science international.
2003 Apr; 133(1-2):39-46. doi:
10.1016/s0379-0738(03)00048-3. [PMID: 12742688] - Stefan W Toennes, Gerold F Kauert. Excretion and detection of cathinone, cathine, and phenylpropanolamine in urine after kath chewing.
Clinical chemistry.
2002 Oct; 48(10):1715-9. doi:
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Clinical pharmacology and therapeutics.
2002 Jun; 71(6):421-32. doi:
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Journal of chromatographic science.
2001 Sep; 39(9):370-4. doi:
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Pharmacy world & science : PWS.
1999 Feb; 21(1):44-6. doi:
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Journal of analytical toxicology.
1998 Jan; 22(1):55-60. doi:
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Pharmacy world & science : PWS.
1996 Apr; 18(2):69-73. doi:
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Pharmacology, biochemistry, and behavior.
1996 Feb; 53(2):297-301. doi:
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1994; 29(5):375-9. doi:
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Journal of ethnopharmacology.
1993 Aug; 39(3):213-6. doi:
10.1016/0378-8741(93)90039-8. [PMID: 7903110] - K Mathys, R Brenneisen. Determination of (S)-(-)-cathinone and its metabolites (R,S)-(-)-norephedrine and (R,R)-(-)-norpseudoephedrine in urine by high-performance liquid chromatography with photodiode-array detection.
Journal of chromatography.
1992 Feb; 593(1-2):79-85. doi:
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Pharmacology, biochemistry, and behavior.
1990 Jun; 36(2):267-71. doi:
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1989; 24(11):865-71. doi:
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Journal of ethnopharmacology.
1988 May; 23(1):19-26. doi:
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Clinical chemistry.
1987 Sep; 33(9):1678. doi:
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Journal of ethnopharmacology.
1987 Sep; 21(1):85-90. doi:
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Appetite.
1987 Aug; 9(1):31-7. doi:
10.1016/0195-6663(87)90051-1. [PMID: 3662492] - S Geisshüsler, R Brenneisen. The content of psychoactive phenylpropyl and phenylpentenyl khatamines in Catha edulis Forsk. of different origin.
Journal of ethnopharmacology.
1987 May; 19(3):269-77. doi:
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The Journal of pharmacy and pharmacology.
1987 Feb; 39(2):135-7. doi:
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Pharmacology.
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The Journal of pharmacy and pharmacology.
1986 Apr; 38(4):298-300. doi:
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Environmental mutagenesis.
1984; 6(6):851-60. doi:
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Human toxicology.
1983 Apr; 2(2):197-203. doi:
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East African medical journal.
1982 Jun; 59(6):394-8. doi:
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Life sciences.
1982 May; 30(21):1817-26. doi:
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Pharmaceutica acta Helvetiae.
1982; 57(1):12-5. doi:
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Life sciences.
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Bulletin on narcotics.
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