Deuterium Oxide (BioDeep_00000839595)

   


代谢物信息卡片


Deuterium Oxide

化学式: H2O (18.0105642)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: O
InChI: InChI=1S/H2O/h1H2/i/hD2

描述信息

D020011 - Protective Agents > D011837 - Radiation-Protective Agents
D000970 - Antineoplastic Agents

同义名列表

1 个代谢物同义名

Deuterium Oxide



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Christopher M Salinas, Eric Reichel, Abhiman Gupta, Russell S Witte. Heavy water coupling gel for short-wave infrared photoacoustic imaging. Journal of biomedical optics. 2023 11; 28(11):116001. doi: 10.1117/1.jbo.28.11.116001. [PMID: 38078156]
  • Sergey Osipenko, Anton Bashilov, Anna Vishnevskaya, Lidiia Rumiantseva, Anna Levashova, Anna Kovalenko, Boris Tupertsev, Albert Kireev, Eugene Nikolaev, Yury Kostyukevich. Investigating the Metabolism of Plants Germinated in Heavy Water, D2O, and H218O-Enriched Media Using High-Resolution Mass Spectrometry. International journal of molecular sciences. 2023 Oct; 24(20):. doi: 10.3390/ijms242015396. [PMID: 37895078]
  • Bharath, K Arya Krishnan, Renita Shiny D'Souza, S Rashmi Nayak, B N Dileep, P M Ravi, S S Mangavi, G S Salunke, D Veerendra, N Karunakara. Carbon-14 emission from the pressurized heavy water reactor nuclear power plant at Kaiga, India. Journal of environmental radioactivity. 2022 Dec; 255(?):107006. doi: 10.1016/j.jenvrad.2022.107006. [PMID: 36162146]
  • Álvaro Morón, Ana Martín-González, Silvia Díaz, Juan Carlos Gutiérrez, Francisco Amaro. Autophagy and lipid droplets are a defense mechanism against toxic copper oxide nanotubes in the eukaryotic microbial model Tetrahymena thermophila. The Science of the total environment. 2022 Nov; 847(?):157580. doi: 10.1016/j.scitotenv.2022.157580. [PMID: 35882336]
  • Chengshun Jiang, Yan Liu, Lianghua Wang, Feng Lu. Interaction between Heavy Water and Single-Strand DNA: A SERS Study. Molecules (Basel, Switzerland). 2022 Sep; 27(18):. doi: 10.3390/molecules27186023. [PMID: 36144761]
  • Eric J Lawitz, Kelvin W Li, Edna Nyangau, Tyler John Field, Jen-Chieh Chuang, Andrew Billin, Lulu Wang, Ya Wang, Ryan S Huss, Chuhan Chung, G Mani Subramanian, Robert P Myers, Marc K Hellerstein. Elevated de novo lipogenesis, slow liver triglyceride turnover, and clinical correlations in nonalcoholic steatohepatitis patients. Journal of lipid research. 2022 09; 63(9):100250. doi: 10.1016/j.jlr.2022.100250. [PMID: 35835205]
  • Oladipo Oladiti Olaniyi, Hongzhe Li, Yongguan Zhu, Li Cui. Metabolic responses of indigenous bacteria in chicken faeces and maggots to multiple antibiotics via heavy water labeled single-cell Raman spectroscopy. Journal of environmental sciences (China). 2022 Mar; 113(?):394-402. doi: 10.1016/j.jes.2021.06.024. [PMID: 34963547]
  • Kim Pauwaert, Samuel Bodé, Upeshka Sewwandi Alwis, Toon Mylle, Pascal Boeckx, Joris Delanghe, Karel Everaert, Saskia Roggeman. Observing the water handling in humans to resolve the role of the interstitium: preliminary results of the usability of deuterium oxide and bio-impedance analysis - a pilot analysis. Isotopes in environmental and health studies. 2022 Mar; 58(1):99-110. doi: 10.1080/10256016.2022.2026349. [PMID: 35072572]
  • Gopalakrishnan Sarojini, Samikannu Venkateshbabu, Manivasagan Rajasimman. Facile synthesis and characterization of polypyrrole - iron oxide - seaweed (PPy-Fe3O4-SW) nanocomposite and its exploration for adsorptive removal of Pb(II) from heavy metal bearing water. Chemosphere. 2021 Sep; 278(?):130400. doi: 10.1016/j.chemosphere.2021.130400. [PMID: 33819882]
  • Mitsugu Sujino, Satoshi Koinuma, Yoichi Minami, Yasufumi Shigeyoshi. Heavy Water Lengthens the Molecular Circadian Clock Period in the Suprachiasmatic Nucleus of Mice In Vitro. Journal of biological rhythms. 2021 08; 36(4):410-418. doi: 10.1177/07487304211012905. [PMID: 33969745]
  • Stephanie L Silveira, Brenda Jeng, Barbara A Gower, Robert W Motl. Feasibility, Acceptability, and Preliminary Validity of Self-Report Dietary Assessment in Adults with Multiple Sclerosis: Comparison with Doubly Labeled Water Measured Total Energy Expenditure. Nutrients. 2021 Apr; 13(4):. doi: 10.3390/nu13041198. [PMID: 33916406]
  • Maryam Hekmatara, Mohammadhadi Heidari Baladehi, Yuetong Ji, Jian Xu. D2O-Probed Raman Microspectroscopy Distinguishes the Metabolic Dynamics of Macromolecules in Organellar Anticancer Drug Response. Analytical chemistry. 2021 02; 93(4):2125-2134. doi: 10.1021/acs.analchem.0c03925. [PMID: 33435684]
  • S B Kim, M Bredlaw, A Festarini, C Bucur, I Popescu, M Constantinescu, F Bucura, H Rousselle, D Beaton, V Y Korolevych, G Chen, M Stuart. Experimental investigation of D2 conversion to DHO in soil near the Cernavoda nuclear power plant site in Romania. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 2021 Feb; 168(?):109403. doi: 10.1016/j.apradiso.2020.109403. [PMID: 33131993]
  • Lin Chen, Jing Liu, Chengyan Chu, Zheng Han, Nirhbay Yadav, Jiadi Xu, Renyuan Bai, Verena Staedtke, Monica Pearl, Piotr Walczak, Peter van Zijl, Miroslaw Janowski, Guanshu Liu. Deuterium oxide as a contrast medium for real-time MRI-guided endovascular neurointervention. Theranostics. 2021; 11(13):6240-6250. doi: 10.7150/thno.55953. [PMID: 33995656]
  • Eisuke Tomiyama, Kazutoshi Fujita, Norio Nonomura. Urinary Extracellular Vesicles: Ultracentrifugation Method. Methods in molecular biology (Clifton, N.J.). 2021; 2292(?):173-181. doi: 10.1007/978-1-0716-1354-2_15. [PMID: 33651361]
  • Yali Liu, Dominique Jasmin Lunter. Tracking heavy-water-incorporated confocal Raman spectroscopy for evaluating the effects of PEGylated emulsifiers on skin barrier. Journal of biophotonics. 2020 12; 13(12):e202000286. doi: 10.1002/jbio.202000286. [PMID: 32975040]
  • Erika Aloi, Rosa Bartucci. Cryogenically frozen PEGylated liposomes and micelles: Water penetration and polarity profiles. Biophysical chemistry. 2020 11; 266(?):106463. doi: 10.1016/j.bpc.2020.106463. [PMID: 32911450]
  • Celeste K L Cravalho, Abby G Meyers, Lilian S Mabundo, Amber Courville, Shanna Yang, Hongyi Cai, Yuhai Dai, Mary Walter, Peter J Walter, Susan Sharma, Shaji Chacko, Fran Cogen, Sheela N Magge, Morey W Haymond, Stephanie T Chung. Metformin improves blood glucose by increasing incretins independent of changes in gluconeogenesis in youth with type 2 diabetes. Diabetologia. 2020 10; 63(10):2194-2204. doi: 10.1007/s00125-020-05236-y. [PMID: 32728891]
  • O L Mantha, J-F Huneau, V Mathé, D Hermier, N Khodorova, F Mariotti, H Fouillet. Differential changes to splanchnic and peripheral protein metabolism during the diet-induced development of metabolic syndrome in rats. American journal of physiology. Endocrinology and metabolism. 2020 07; 319(1):E175-E186. doi: 10.1152/ajpendo.00061.2020. [PMID: 32459526]
  • Veronika Paluchova, Marina Oseeva, Marie Brezinova, Tomas Cajka, Kristina Bardova, Katerina Adamcova, Petr Zacek, Kristyna Brejchova, Laurence Balas, Hana Chodounska, Eva Kudova, Renate Schreiber, Rudolf Zechner, Thierry Durand, Martin Rossmeisl, Nada A Abumrad, Jan Kopecky, Ondrej Kuda. Lipokine 5-PAHSA Is Regulated by Adipose Triglyceride Lipase and Primes Adipocytes for De Novo Lipogenesis in Mice. Diabetes. 2020 03; 69(3):300-312. doi: 10.2337/db19-0494. [PMID: 31806624]
  • Eric Matsiko, Paul J M Hulshof, Laura van der Velde, Marlou-Floor Kenkhuis, Lisine Tuyisenge, Alida Melse-Boonstra. Comparing saliva and urine samples for measuring breast milk intake with the 2H oxide dose-to-mother technique among children 2-4 months old. The British journal of nutrition. 2020 01; 123(2):232-240. doi: 10.1017/s0007114519002642. [PMID: 31623693]
  • Joachim Kloehn, Malcolm J McConville. Analysis of the Physiological and Metabolic State of Leishmania Using Heavy Water Labeling. Methods in molecular biology (Clifton, N.J.). 2020; 2116(?):587-609. doi: 10.1007/978-1-0716-0294-2_35. [PMID: 32221944]
  • J Mueller, M Trapp, R H H Neubert. The effect of hydrophilic penetration/diffusion enhancer on stratum corneum lipid models: Part II*: DMSO. Chemistry and physics of lipids. 2019 12; 225(?):104816. doi: 10.1016/j.chemphyslip.2019.104816. [PMID: 31525381]
  • Hong-Lei Hu, Jian Gao, Wen-Jun Guo, Feng-Hua Zhou, Hong-Yan Liu, Chang-Chun Su. [Anti-injury effect of hydrogen-enriched water in a rat model of liver injury induced by aflatoxin B1]. Sheng li xue bao : [Acta physiologica Sinica]. 2019 Oct; 71(5):725-731. doi: NULL. [PMID: 31646326]
  • Kristina Elisa Haslauer, Daniel Hemmler, Philippe Schmitt-Kopplin, Silke Sophie Heinzmann. Guidelines for the Use of Deuterium Oxide (D2O) in 1H NMR Metabolomics. Analytical chemistry. 2019 09; 91(17):11063-11069. doi: 10.1021/acs.analchem.9b01580. [PMID: 31397558]
  • Andrew G Siddall, Steven D Powell, Sarah C Needham-Beck, Victoria C Edwards, Jane E S Thompson, Sarah S Kefyalew, Priya A Singh, Elise R Orford, Michelle C Venables, Sarah Jackson, Julie P Greeves, Sam D Blacker, Steve D Myers. Validity of energy expenditure estimation methods during 10 days of military training. Scandinavian journal of medicine & science in sports. 2019 Sep; 29(9):1313-1321. doi: 10.1111/sms.13488. [PMID: 31136027]
  • Erika Aloi, Rosa Bartucci. Solvent accessibility in interdigitated and micellar phases formed by DPPC/Lyso-PPC mixtures: D2O-ESEEM of chain labeled lipids. Chemistry and physics of lipids. 2019 07; 221(?):39-45. doi: 10.1016/j.chemphyslip.2019.03.005. [PMID: 30876868]
  • Katherine J Desneves, Maya G Panisset, Jillian Rafferty, Helena Rodi, Leigh C Ward, Andrew Nunn, Mary P Galea. Comparison of estimated energy requirements using predictive equations with total energy expenditure measured by the doubly labelled water method in acute spinal cord injury. Spinal cord. 2019 Jul; 57(7):562-570. doi: 10.1038/s41393-019-0253-9. [PMID: 30728440]
  • Natalie A Daurio, Yichen Wang, Ying Chen, Haihong Zhou, Ester Carballo-Jane, Joel Mane, Carlos G Rodriguez, Peter Zafian, Andrea Houghton, George Addona, David G McLaren, Rena Zhang, Bao Jen Shyong, Kevin Bateman, Daniel P Downes, Maria Webb, David E Kelley, Stephen F Previs. Spatial and temporal studies of metabolic activity: contrasting biochemical kinetics in tissues and pathways during fasted and fed states. American journal of physiology. Endocrinology and metabolism. 2019 06; 316(6):E1105-E1117. doi: 10.1152/ajpendo.00459.2018. [PMID: 30912961]
  • Jessica Nouws, Mark Fitch, Mariana Mata, Nicola Santoro, Brittany Galuppo, Romy Kursawe, Deepak Narayan, Alla Vash-Margita, Bridget Pierpont, Gerald I Shulman, Marc Hellerstein, Sonia Caprio. Altered In Vivo Lipid Fluxes and Cell Dynamics in Subcutaneous Adipose Tissues Are Associated With the Unfavorable Pattern of Fat Distribution in Obese Adolescent Girls. Diabetes. 2019 06; 68(6):1168-1177. doi: 10.2337/db18-1162. [PMID: 30936147]
  • UkJae Lee, Woo Nyun Choi, Hee Reyoung Kim. Radiological impact assessment for workers on treatment of radioactive spent resin from heavy water reactors. Journal of radiological protection : official journal of the Society for Radiological Protection. 2019 Jun; 39(2):422-442. doi: 10.1088/1361-6498/ab039d. [PMID: 30703752]
  • Kai Yang, Hong-Zhe Li, Xuan Zhu, Jian-Qiang Su, Bin Ren, Yong-Guan Zhu, Li Cui. Rapid Antibiotic Susceptibility Testing of Pathogenic Bacteria Using Heavy-Water-Labeled Single-Cell Raman Spectroscopy in Clinical Samples. Analytical chemistry. 2019 05; 91(9):6296-6303. doi: 10.1021/acs.analchem.9b01064. [PMID: 30942570]
  • Zhi-P Cai, Louis P Conway, Ying Y Huang, Wen J Wang, Pedro Laborda, Ting Wang, Ai M Lu, Hong L Yao, Kun Huang, Sabine L Flitsch, Li Liu, Josef Voglmeir. Enzymatic Synthesis of Trideuterated Sialosides. Molecules (Basel, Switzerland). 2019 Apr; 24(7):. doi: 10.3390/molecules24071368. [PMID: 30965582]
  • Sarah Waldie, Martine Moulin, Lionel Porcar, Harald Pichler, Gernot A Strohmeier, Maximilian Skoda, V Trevor Forsyth, Michael Haertlein, Selma Maric, Marité Cárdenas. The Production of Matchout-Deuterated Cholesterol and the Study of Bilayer-Cholesterol Interactions. Scientific reports. 2019 03; 9(1):5118. doi: 10.1038/s41598-019-41439-z. [PMID: 30914734]
  • Hong-Zhe Li, Qing-Fang Bi, Kai Yang, Bang-Xiao Zheng, Qiang Pu, Li Cui. D2O-Isotope-Labeling Approach to Probing Phosphate-Solubilizing Bacteria in Complex Soil Communities by Single-Cell Raman Spectroscopy. Analytical chemistry. 2019 02; 91(3):2239-2246. doi: 10.1021/acs.analchem.8b04820. [PMID: 30608659]
  • Fredrik Rosqvist, Catriona A McNeil, Camilla Pramfalk, Sion A Parry, Wee Suan Low, Thomas Cornfield, Barbara A Fielding, Leanne Hodson. Fasting hepatic de novo lipogenesis is not reliably assessed using circulating fatty acid markers. The American journal of clinical nutrition. 2019 02; 109(2):260-268. doi: 10.1093/ajcn/nqy304. [PMID: 30721918]
  • Ying Tian, Minghui Shi, Qianqian Dai, Chanfang Meng, Ruixia Gu, Jing Peng, Yu Chen, Yunsheng Jiang. The fractional synthesis rates of plasma proteins as determined using deuterated water are sensitive to dietary intake of lysine in rats. Amino acids. 2018 Dec; 50(12):1719-1727. doi: 10.1007/s00726-018-2645-0. [PMID: 30178102]
  • Mouhamad Reslan, Veysel Kayser. The effect of deuterium oxide on the conformational stability and aggregation of bovine serum albumin. Pharmaceutical development and technology. 2018 Dec; 23(10):1030-1036. doi: 10.1080/10837450.2016.1268157. [PMID: 27910726]
  • Claire Gaudichon, Hai-Yen Ta, Nadezda V Khodorova, Marion Oberli, Isabelle Breton, Robert Benamouzig, Daniel Tomé, Jean-Philippe Godin. Time course of fractional gluconeogenesis after meat ingestion in healthy adults: a D2O study. American journal of physiology. Endocrinology and metabolism. 2018 10; 315(4):E454-E459. doi: 10.1152/ajpendo.00157.2018. [PMID: 29920213]
  • Lingyan Shi, Chaogu Zheng, Yihui Shen, Zhixing Chen, Edilson S Silveira, Luyuan Zhang, Mian Wei, Chang Liu, Carmen de Sena-Tomas, Kimara Targoff, Wei Min. Optical imaging of metabolic dynamics in animals. Nature communications. 2018 08; 9(1):2995. doi: 10.1038/s41467-018-05401-3. [PMID: 30082908]
  • Stephen F Previs, Kithsiri Herath, Andrea R Nawrocki, Carlos G Rodriguez, Deborah Slipetz, Sheo B Singh, Ling Kang, Gowri Bhat, Thomas P Roddy, Stacey Conarello, Jenna Terebetski, Mark D Erion, David E Kelley. Using [2H]water to quantify the contribution of de novo palmitate synthesis in plasma: enabling back-to-back studies. American journal of physiology. Endocrinology and metabolism. 2018 07; 315(1):E63-E71. doi: 10.1152/ajpendo.00010.2017. [PMID: 29351479]
  • Byoungsook Goh, Jinwoo Kim, Seungwoo Seo, Tae-Young Kim. High-Throughput Measurement of Lipid Turnover Rates Using Partial Metabolic Heavy Water Labeling. Analytical chemistry. 2018 06; 90(11):6509-6518. doi: 10.1021/acs.analchem.7b05428. [PMID: 29722958]
  • Pär Håkansson, Tom Boirin, Juha Vaara. Brownian Translational Dynamics on a Flexible Surface: Nuclear Spin Relaxation of Fluid Membrane Phases. Langmuir : the ACS journal of surfaces and colloids. 2018 03; 34(12):3755-3766. doi: 10.1021/acs.langmuir.7b04156. [PMID: 29478324]
  • Mutez Ali Ahmed, Mohsen Zarebanadkouki, Félicien Meunier, Mathieu Javaux, Anders Kaestner, Andrea Carminati. Root type matters: measurement of water uptake by seminal, crown, and lateral roots in maize. Journal of experimental botany. 2018 02; 69(5):1199-1206. doi: 10.1093/jxb/erx439. [PMID: 29304205]
  • Fredd Vergara, Misao Itouga, Roberto Gamboa Becerra, Masami Hirai, José Juan Ordaz-Ortiz, Robert Winkler. Funaria hygrometrica Hedw. elevated tolerance to D2O: its use for the production of highly deuterated metabolites. Planta. 2018 Feb; 247(2):405-412. doi: 10.1007/s00425-017-2794-5. [PMID: 29030693]
  • Svetlana V Blokhina, Tatyana V Volkova, Vasiliy A Golubev, German L Perlovich. Understanding of Relationship between Phospholipid Membrane Permeability and Self-Diffusion Coefficients of Some Drugs and Biologically Active Compounds in Model Solvents. Molecular pharmaceutics. 2017 10; 14(10):3381-3390. doi: 10.1021/acs.molpharmaceut.7b00401. [PMID: 28850240]
  • E N Ferjak, C A Cavinder, D D Burnett, C Mc Argo, T T N Dinh. Body fat of stock-type horses predicted by rump fat thickness and deuterium oxide dilution and validated by near-infrared spectroscopy of dissected tissues. Journal of animal science. 2017 Oct; 95(10):4344-4351. doi: 10.2527/jas2017.1676. [PMID: 29108049]
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  • Leonie van 't Hag, Liliana de Campo, Christopher J Garvey, George C Feast, Anna E Leung, Nageshwar Rao Yepuri, Robert Knott, Tamar L Greaves, Nhiem Tran, Sally L Gras, Calum J Drummond, Charlotte E Conn. Using SANS with Contrast-Matched Lipid Bicontinuous Cubic Phases To Determine the Location of Encapsulated Peptides, Proteins, and Other Biomolecules. The journal of physical chemistry letters. 2016 Jul; 7(14):2862-6. doi: 10.1021/acs.jpclett.6b01173. [PMID: 27414483]
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  • Thushari Bandara, Manjula Hettiarachchi, Chandrani Liyanage, Sujeewa Amarasena, William W Wong. The Deuterium Oxide-to-the-Mother Method Documents Adequate Breast-Milk Intake among Sri Lankan Infants. The Journal of nutrition. 2015 Jun; 145(6):1325-9. doi: 10.3945/jn.115.211771. [PMID: 25904731]
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  • I Chery, A Zahariev, C Simon, S Blanc. Analytical aspects of measuring (2)H/(1)H and (18)O/(16)O ratios in urine from doubly labelled water studies by high-temperature conversion elemental analyser-isotope-ratio mass spectrometry. Rapid communications in mass spectrometry : RCM. 2015 Apr; 29(7):562-72. doi: 10.1002/rcm.7135. [PMID: 26212273]
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