6,4-Dihydroxy-3-methyl-3,5-dibromoflavone (BioDeep_00000839349)
代谢物信息卡片
化学式: C16H10Br2O4 (423.894578)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(OC2=C(C1=O)C=C(C=C2)O)C3=CC(=C(C(=C3)Br)O)Br
InChI: InChI=1S/C16H10Br2O4/c1-7-14(20)10-6-9(19)2-3-13(10)22-16(7)8-4-11(17)15(21)12(18)5-8/h2-6,19,21H,1H3
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- J P Schröder-van der Elst, D van der Heide, H Rokos, J Köhrle, G Morreale de Escobar. Different tissue distribution, elimination, and kinetics of thyroxine and its conformational analog, the synthetic flavonoid EMD 49209 in the rat.
Endocrinology.
1997 Jan; 138(1):79-84. doi:
10.1210/endo.138.1.4848. [PMID: 8977388] - C F Lim, N M Loidl, J A Kennedy, D J Topliss, J R Stockigt. Drug effects on triiodothyronine uptake by rat anterior pituitary cells in vitro.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association.
1996; 104(2):151-7. doi:
10.1055/s-0029-1211437. [PMID: 8740939] - J W Barlow, A J Curtis, L E Raggatt, N M Loidl, D J Topliss, J R Stockigt. Drug competition for intracellular triiodothyronine-binding sites.
European journal of endocrinology.
1994 Apr; 130(4):417-21. doi:
10.1530/eje.0.1300417. [PMID: 8162174] - H N Rosen, J R Murrell, J J Liepnieks, M D Benson, V Cody, A C Moses. Threonine for alanine substitution at position 109 of transthyretin differentially alters human transthyretin's affinity for iodothyronines.
Endocrinology.
1994 Jan; 134(1):27-34. doi:
10.1210/endo.134.1.8275943. [PMID: 8275943] - C M Mendel, R R Cavalieri, J Köhrle. Thyroxine (T4) transport and distribution in rats treated with EMD 21388, a synthetic flavonoid that displaces T4 from transthyretin.
Endocrinology.
1992 Mar; 130(3):1525-32. doi:
10.1210/endo.130.3.1537302. [PMID: 1537302] - J P Chanoine, S Alex, S L Fang, S Stone, J L Leonard, J Körhle, L E Braverman. Role of transthyretin in the transport of thyroxine from the blood to the choroid plexus, the cerebrospinal fluid, and the brain.
Endocrinology.
1992 Feb; 130(2):933-8. doi:
10.1210/endo.130.2.1733735. [PMID: 1733735] - J P Schröder-van der Elst, D van der Heide, J Köhrle. In vivo effects of flavonoid EMD 21388 on thyroid hormone secretion and metabolism in rats.
The American journal of physiology.
1991 Aug; 261(2 Pt 1):E227-32. doi:
10.1152/ajpendo.1991.261.2.e227. [PMID: 1872384] - W Lueprasitsakul, S Alex, S L Fang, S Pino, K Irmscher, J Köhrle, L E Braverman. Flavonoid administration immediately displaces thyroxine (T4) from serum transthyretin, increases serum free T4, and decreases serum thyrotropin in the rat.
Endocrinology.
1990 Jun; 126(6):2890-5. doi:
10.1210/endo-126-6-2890. [PMID: 2351100] - J Köhrle, S L Fang, Y Yang, K Irmscher, R D Hesch, S Pino, S Alex, L E Braverman. Rapid effects of the flavonoid EMD 21388 on serum thyroid hormone binding and thyrotropin regulation in the rat.
Endocrinology.
1989 Jul; 125(1):532-7. doi:
10.1210/endo-125-1-532. [PMID: 2737161] - J Köhrle, M Spanka, K Irmscher, R D Hesch. Flavonoid effects on transport, metabolism and action of thyroid hormones.
Progress in clinical and biological research.
1988; 280(?):323-40. doi:
NULL. [PMID: 3140249]