Thiodigalactoside (BioDeep_00000838796)
代谢物信息卡片
化学式: C12H22O10S (358.0934)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(C1C(C(C(C(O1)SC2C(C(C(C(O2)CO)O)O)O)O)O)O)O
InChI: InChI=1S/C12H22O10S/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12/h3-20H,1-2H2/t3-,4-,5+,6+,7+,8+,9-,10-,11+,12+/m1/s1
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Hao Zhang, Dominic Laaf, Lothar Elling, Roland J Pieters. Thiodigalactoside-Bovine Serum Albumin Conjugates as High-Potency Inhibitors of Galectin-3: An Outstanding Example of Multivalent Presentation of Small Molecule Inhibitors.
Bioconjugate chemistry.
2018 04; 29(4):1266-1275. doi:
10.1021/acs.bioconjchem.8b00047. [PMID: 29474087] - Hilal Ahmad Parray, Jong Won Yun. Combined inhibition of autophagy protein 5 and galectin-1 by thiodigalactoside reduces diet-induced obesity through induction of white fat browning.
IUBMB life.
2017 07; 69(7):510-521. doi:
10.1002/iub.1634. [PMID: 28444942] - Peiwen Kuo, Scott V Bratman, David B Shultz, Rie von Eyben, Cato Chan, Ziwei Wang, Carmen Say, Aparna Gupta, Bill W Loo, Amato J Giaccia, Albert C Koong, Maximilian Diehn, Quynh-Thu Le. Galectin-1 mediates radiation-related lymphopenia and attenuates NSCLC radiation response.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2014 Nov; 20(21):5558-69. doi:
10.1158/1078-0432.ccr-14-1138. [PMID: 25189484] - Sonsoles Martín-Santamaría, Sabine André, Eliza Buzamet, Rémi Caraballo, Gloria Fernández-Cureses, Maria Morando, João P Ribeiro, Karla Ramírez-Gualito, Beatriz de Pascual-Teresa, F Javier Cañada, Margarita Menéndez, Olof Ramström, Jesús Jiménez-Barbero, Dolores Solís, Hans-Joachim Gabius. Symmetric dithiodigalactoside: strategic combination of binding studies and detection of selectivity between a plant toxin and human lectins.
Organic & biomolecular chemistry.
2011 Aug; 9(15):5445-55. doi:
10.1039/c0ob01235a. [PMID: 21660340] - John Holyoake, Mark S P Sansom. Conformational change in an MFS protein: MD simulations of LacY.
Structure (London, England : 1993).
2007 Jul; 15(7):873-84. doi:
10.1016/j.str.2007.06.004. [PMID: 17637346] - K M Murphy, S E Zalik. Endogenous galectins and effect of galectin hapten inhibitors on the differentiation of the chick mesonephros.
Developmental dynamics : an official publication of the American Association of Anatomists.
1999 Jul; 215(3):248-63. doi:
10.1002/(sici)1097-0177(199907)215:3<248::aid-aja7>3.0.co;2-b. [PMID: 10398535] - J Jeeva, S E Zalik. Hapten inhibitors of the endogenous galactose binding lectins and anti-lectin antibodies inhibit primitive streak formation in the early chick embryo.
Glycobiology.
1996 Jul; 6(5):517-26. doi:
10.1093/glycob/6.5.517. [PMID: 8877372] - K Dornmair, P Overath, F Jähnig. Fast measurement of galactoside transport by lactose permease.
The Journal of biological chemistry.
1989 Jan; 264(1):342-6. doi:
10.1016/s0021-9258(17)31263-2. [PMID: 2642475]
