Gacyclidine (BioDeep_00000838754)
代谢物信息卡片
化学式: C16H25NS (263.170761)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1CCCCC1(C2=CC=CS2)N3CCCCC3
InChI: InChI=1S/C16H25NS/c1-14-8-3-4-10-16(14,15-9-7-13-18-15)17-11-5-2-6-12-17/h7,9,13-14H,2-6,8,10-12H2,1H3/t14-,16+/m0/s1
描述信息
D018377 - Neurotransmitter Agents > D018683 - Excitatory Amino Acid Agents > D018691 - Excitatory Amino Acid Antagonists
D002491 - Central Nervous System Agents > D018696 - Neuroprotective Agents
C26170 - Protective Agent > C1509 - Neuroprotective Agent
D020011 - Protective Agents
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- J A Chenoweth, R R Gerona, J B Ford, M E Sutter, J S Rose, T E Albertson, S O Clarke, K P Owen. Altered mental status and end organ damage associated with the use of gacyclidine: a case series.
Journal of medical toxicology : official journal of the American College of Medical Toxicology.
2015 Mar; 11(1):115-20. doi:
10.1007/s13181-014-0415-2
. [PMID: 25048606] - G Hoizey, M L Kaltenbach, S Dukic, D Lamiable, H Millart, P D'Arbigny, R Vistelle. Pharmacokinetics of gacyclidine enantiomers in plasma and spinal cord after single enantiomer administration in rats.
International journal of pharmaceutics.
2001 Oct; 229(1-2):147-53. doi:
10.1016/s0378-5173(01)00842-0
. [PMID: 11604267] - G Hoizey, M L Kaltenbach, S Dukic, D Lamiable, A Lallemand, H Millart, P D'Arbigny, R Vistelle. Distribution of gacyclidine enantiomers after experimental spinal cord injury in rats: possible involvement of an active transport system.
Journal of pharmaceutical sciences.
2001 Jan; 90(1):70-8. doi:
10.1002/1520-6017(200101)90:1<70::aid-jps8>3.0.co;2-e
. [PMID: 11064380] - G Hoizey, M L Kaltenbach, S Dukic, D Lamiable, A Lallemand, P D'Arbigny, H Millart, R Vistelle. Distribution of gacyclidine enantiomers in spinal cord extracellular fluid.
Pharmaceutical research.
2000 Feb; 17(2):148-53. doi:
10.1023/a:1007557028313
. [PMID: 10751028] - G Hoizey, D Lamiable, S Dukic, H Millart, P d'Arbigny, R Vistelle. Sensitive gas chromatographic-mass spectrometric method for the determination of gacyclidine in rat plasma and spinal cord dialyzates.
The Analyst.
1999 Dec; 124(12):1761-4. doi:
10.1039/a905522c
. [PMID: 10746308] - G Hoizey, N Baccard, B Gourdier, D Lamiable, H Millart, P D'Arbigny, R Vistelle. Modified gas chromatographic-mass spectrometric assay for the determination of gacyclidine enantiomers in human plasma.
Journal of chromatography. B, Biomedical sciences and applications.
1999 Aug; 731(2):317-22. doi:
10.1016/s0378-4347(99)00252-2
. [PMID: 10510786]