Phosphomethylphosphonic acid adenylate ester (BioDeep_00000838616)

   


代谢物信息卡片


Phosphomethylphosphonic acid adenylate ester

化学式: C11H18N5O12P3 (505.0164818)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)OP(=O)(CP(=O)(O)O)O)O)O)N
InChI: InChI=1S/C11H18N5O12P3/c12-9-6-10(14-2-13-9)16(3-15-6)11-8(18)7(17)5(27-11)1-26-31(24,25)28-30(22,23)4-29(19,20)21/h2-3,5,7-8,11,17-18H,1,4H2,(H,22,23)(H,24,25)(H2,12,13,14)(H2,19,20,21)/t5-,7-,8-,11-/m1/s1

描述信息

同义名列表

1 个代谢物同义名

Phosphomethylphosphonic acid adenylate ester



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Zhengrong Guan, Sean T Singletary, Haword Cha, Justin P Van Beusecum, Anthony K Cook, Jennifer S Pollock, David M Pollock, Edward W Inscho. Pentosan polysulfate preserves renal microvascular P2X1 receptor reactivity and autoregulatory behavior in DOCA-salt hypertensive rats. American journal of physiology. Renal physiology. 2016 Mar; 310(6):F456-65. doi: 10.1152/ajprenal.00110.2015. [PMID: 26697978]
  • Swetha Raman, Kaza Suguna. Functional characterization of heat-shock protein 90 from Oryza sativa and crystal structure of its N-terminal domain. Acta crystallographica. Section F, Structural biology communications. 2015 Jun; 71(Pt 6):688-96. doi: 10.1107/s2053230x15006639. [PMID: 26057797]
  • Ryan P Emptage, Charles W Pemble, John D York, Christian R H Raetz, Pei Zhou. Mechanistic characterization of the tetraacyldisaccharide-1-phosphate 4'-kinase LpxK involved in lipid A biosynthesis. Biochemistry. 2013 Apr; 52(13):2280-90. doi: 10.1021/bi400097z. [PMID: 23464738]
  • Zhengrong Guan, Matthew I Giddens, David A Osmond, Anthony K Cook, Janet L Hobbs, Shali Zhang, Tatsuo Yamamoto, Jennifer S Pollock, David M Pollock, Edward W Inscho. Immunosuppression preserves renal autoregulatory function and microvascular P2X(1) receptor reactivity in ANG II-hypertensive rats. American journal of physiology. Renal physiology. 2013 Mar; 304(6):F801-7. doi: 10.1152/ajprenal.00286.2012. [PMID: 23269644]
  • Byung-Chang Suh, Karina Leal, Bertil Hille. Modulation of high-voltage activated Ca(2+) channels by membrane phosphatidylinositol 4,5-bisphosphate. Neuron. 2010 Jul; 67(2):224-38. doi: 10.1016/j.neuron.2010.07.001. [PMID: 20670831]
  • Guillermo B Silva, Jeffrey L Garvin. Extracellular ATP inhibits transport in medullary thick ascending limbs: role of P2X receptors. American journal of physiology. Renal physiology. 2009 Nov; 297(5):F1168-73. doi: 10.1152/ajprenal.00325.2009. [PMID: 19710240]
  • Martin Picard, Anne-Marie Lund Jensen, Thomas L-M Sørensen, Philippe Champeil, Jesper Vuust Møller, Poul Nissen. Ca2+ versus Mg2+ coordination at the nucleotide-binding site of the sarcoplasmic reticulum Ca2+-ATPase. Journal of molecular biology. 2007 Apr; 368(1):1-7. doi: 10.1016/j.jmb.2007.01.082. [PMID: 17335848]
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  • Stephen Chivasa, Bongani K Ndimba, William J Simon, Keith Lindsey, Antoni R Slabas. Extracellular ATP functions as an endogenous external metabolite regulating plant cell viability. The Plant cell. 2005 Nov; 17(11):3019-34. doi: 10.1105/tpc.105.036806. [PMID: 16199612]
  • Xueying Zhao, Anthony K Cook, Mary Field, Brentan Edwards, Shali Zhang, Zhanying Zhang, Jennifer S Pollock, John D Imig, Edward W Inscho. Impaired Ca2+ signaling attenuates P2X receptor-mediated vasoconstriction of afferent arterioles in angiotensin II hypertension. Hypertension (Dallas, Tex. : 1979). 2005 Sep; 46(3):562-8. doi: 10.1161/01.hyp.0000179584.39937.41. [PMID: 16116048]
  • Yasser Ahmed Mahmmoud, Henrik Vorum, Flemming Cornelius. Interaction of FXYD10 (PLMS) with Na,K-ATPase from shark rectal glands. Close proximity of Cys74 of FXYD10 to Cys254 in the a domain of the alpha-subunit revealed by intermolecular thiol cross-linking. The Journal of biological chemistry. 2005 Jul; 280(30):27776-82. doi: 10.1074/jbc.m503150200. [PMID: 15919665]
  • Beiying Liu, Chunguang Zhang, Feng Qin. Functional recovery from desensitization of vanilloid receptor TRPV1 requires resynthesis of phosphatidylinositol 4,5-bisphosphate. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2005 May; 25(19):4835-43. doi: 10.1523/jneurosci.1296-05.2005. [PMID: 15888659]
  • Jian-Zhong Han, Wen Lin, Yi-Zhang Chen. Inhibition of ATP-induced calcium influx in HT4 cells by glucocorticoids: involvement of protein kinase A. Acta pharmacologica Sinica. 2005 Feb; 26(2):199-204. doi: 10.1111/j.1745-7254.2005.00539.x. [PMID: 15663899]
  • Roger G Pertwee, Ruth A Ross, Susan J Craib, Adèle Thomas. (-)-Cannabidiol antagonizes cannabinoid receptor agonists and noradrenaline in the mouse vas deferens. European journal of pharmacology. 2002 Dec; 456(1-3):99-106. doi: 10.1016/s0014-2999(02)02624-9. [PMID: 12450575]
  • Kenneth A Jacobson, Michael F Jarvis, Michael Williams. Purine and pyrimidine (P2) receptors as drug targets. Journal of medicinal chemistry. 2002 Sep; 45(19):4057-93. doi: 10.1021/jm020046y. [PMID: 12213051]
  • Alex V Birk, M Johan Broekman, Eva M Gladek, Hugh D Robertson, Joan H F Drosopoulos, Aaron J Marcus, Hazel H Szeto. Role of extracellular ATP metabolism in regulation of platelet reactivity. The Journal of laboratory and clinical medicine. 2002 Sep; 140(3):166-75. doi: 10.1067/mlc.2002.126719. [PMID: 12271274]
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  • M Jankowski, M Szczepańska-Konkel, L Kalinowski, S Angielski. Bidirectional action of extracellular ATP on intracapillary volume of isolated rat renal glomeruli. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. 2000 Sep; 51(3):491-6. doi: NULL. [PMID: 11016868]
  • M van der Giet, O Cinkilic, J Jankowski, M Tepel, W Zidek, H Schlüter. Evidence for two different P2X-receptors mediating vasoconstriction of Ap5A and Ap6A in the isolated perfused rat kidney. British journal of pharmacology. 1999 Jul; 127(6):1463-9. doi: 10.1038/sj.bjp.0702667. [PMID: 10455297]
  • A Sonnleitner, S Fleischer, H Schindler. Gating of the skeletal calcium release channel by ATP is inhibited by protein phosphatase 1 but not by Mg2+. Cell calcium. 1997 Apr; 21(4):283-90. doi: 10.1016/s0143-4160(97)90116-0. [PMID: 9160164]
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  • J Simon, T E Webb, B F King, G Burnstock, E A Barnard. Characterisation of a recombinant P2Y purinoceptor. European journal of pharmacology. 1995 Nov; 291(3):281-9. doi: 10.1016/0922-4106(95)90068-3. [PMID: 8719412]
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  • K D Mitchell, L G Navar. Modulation of tubuloglomerular feedback responsiveness by extracellular ATP. The American journal of physiology. 1993 Mar; 264(3 Pt 2):F458-66. doi: 10.1152/ajprenal.1993.264.3.f458. [PMID: 8456958]
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