Benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone (BioDeep_00000838528)

   


代谢物信息卡片


Benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone

化学式: C21H28FN3O7 (453.191119)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)C(C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)CF)NC(=O)OCC1=CC=CC=C1
InChI: InChI=1S/C21H28FN3O7/c1-12(2)18(25-21(31)32-11-14-7-5-4-6-8-14)20(30)23-13(3)19(29)24-15(9-17(27)28)16(26)10-22/h4-8,12-13,15,18H,9-11H2,1-3H3,(H,23,30)(H,24,29)(H,25,31)(H,27,28)/t13-,15-,18-/m0/s1

描述信息

同义名列表

1 个代谢物同义名

Benzyloxycarbonyl-Val-Ala-Asp-fluoromethylketone



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Ling Liu, Dan Shi, Zi-Yi Xia, Bo-Wen Wang, Xue-Li Wang, Xiao-Ting Wang, Guo-Li Wang, Min-Jing Li, Qiu-Sheng Zheng, Defang Li, Bo-Han Li. Gamabufotalin Induces Apoptosis and Cytoprotective Autophagy through the mTOR Signaling Pathway in Hepatocellular Carcinoma. Journal of natural products. 2023 Apr; 86(4):966-978. doi: 10.1021/acs.jnatprod.2c01155. [PMID: 37043698]
  • Ziqiao Yuan, Haoran Zhang, Muhammad Hasnat, Jiaxin Ding, Xi Chen, Peishi Liang, Lixin Sun, Luyong Zhang, Zhenzhou Jiang. A new perspective of triptolide-associated hepatotoxicity: Liver hypersensitivity upon LPS stimulation. Toxicology. 2019 02; 414(?):45-56. doi: 10.1016/j.tox.2019.01.005. [PMID: 30633930]
  • Zhengyang Lu, Guangxin Zhang, Yifan Zhang, Peiyan Hua, Meidan Fang, Meiliang Wu, Tongjun Liu. Isoalantolactone induces apoptosis through reactive oxygen species-dependent upregulation of death receptor 5 in human esophageal cancer cells. Toxicology and applied pharmacology. 2018 08; 352(?):46-58. doi: 10.1016/j.taap.2018.05.026. [PMID: 29800641]
  • Junn-Liang Chang, Jyh-Ming Chow, Jer-Hwa Chang, Yu-Ching Wen, Yung-Wei Lin, Shun-Fa Yang, Wei-Jiunn Lee, Ming-Hsien Chien. Quercetin simultaneously induces G0 /G1 -phase arrest and caspase-mediated crosstalk between apoptosis and autophagy in human leukemia HL-60 cells. Environmental toxicology. 2017 Jul; 32(7):1857-1868. doi: 10.1002/tox.22408. [PMID: 28251795]
  • Wafa Zeriouh, Abdelhafid Nani, Meriem Belarbi, Adélie Dumont, Charlotte de Rosny, Ikram Aboura, Fatima Zahra Ghanemi, Babar Murtaza, Danish Patoli, Charles Thomas, Lionel Apetoh, Cédric Rébé, Dominique Delmas, Naim Akhtar Khan, François Ghiringhelli, Mickael Rialland, Aziz Hichami. Phenolic extract from oleaster (Olea europaea var. Sylvestris) leaves reduces colon cancer growth and induces caspase-dependent apoptosis in colon cancer cells via the mitochondrial apoptotic pathway. PloS one. 2017; 12(2):e0170823. doi: 10.1371/journal.pone.0170823. [PMID: 28212423]
  • Lény Teyssier, Julie Colussi, Stéphanie Delemasure, Johanna Chluba, David Wendehenne, Olivier Lamotte, Jean-Louis Connat. Inflammatory Effects of the Plant Protection Product Stifenia (FEN560) on Vertebrates. Frontiers in public health. 2017; 5(?):74. doi: 10.3389/fpubh.2017.00074. [PMID: 28484691]
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  • Maïté Fransolet, Laurie Henry, Soraya Labied, Agnès Noël, Michelle Nisolle, Carine Munaut. In vitro evaluation of the anti-apoptotic drug Z-VAD-FMK on human ovarian granulosa cell lines for further use in ovarian tissue transplantation. Journal of assisted reproduction and genetics. 2015 Oct; 32(10):1551-9. doi: 10.1007/s10815-015-0536-9. [PMID: 26169075]
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  • Naohide Watanabe, Eric Lam. Two Arabidopsis metacaspases AtMCP1b and AtMCP2b are arginine/lysine-specific cysteine proteases and activate apoptosis-like cell death in yeast. The Journal of biological chemistry. 2005 Apr; 280(15):14691-9. doi: 10.1074/jbc.m413527200. [PMID: 15691845]
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  • Gladys D Ouédraogo, Robert W Redmond. Secondary reactive oxygen species extend the range of photosensitization effects in cells: DNA damage produced via initial membrane photosensitization. Photochemistry and photobiology. 2003 Feb; 77(2):192-203. doi: 10.1562/0031-8655(2003)077<0192:sroset>2.0.co;2. [PMID: 12785059]
  • Antonio Arroyo, Martin Modrianský, F Behice Serinkan, Rosario I Bello, Tatsuya Matsura, Jianfei Jiang, Vladimir A Tyurin, Yulia Y Tyurina, Bengt Fadeel, Valerian E Kagan. NADPH oxidase-dependent oxidation and externalization of phosphatidylserine during apoptosis in Me2SO-differentiated HL-60 cells. Role in phagocytic clearance. The Journal of biological chemistry. 2002 Dec; 277(51):49965-75. doi: 10.1074/jbc.m204513200. [PMID: 12376550]
  • Begona Comin-Anduix, Laszlo G Boros, Silvia Marin, Joan Boren, Carles Callol-Massot, Josep J Centelles, Josep L Torres, Neus Agell, Sara Bassilian, Marta Cascante. Fermented wheat germ extract inhibits glycolysis/pentose cycle enzymes and induces apoptosis through poly(ADP-ribose) polymerase activation in Jurkat T-cell leukemia tumor cells. The Journal of biological chemistry. 2002 Nov; 277(48):46408-14. doi: 10.1074/jbc.m206150200. [PMID: 12351627]
  • Grazyna Nowak. Protein kinase C-alpha and ERK1/2 mediate mitochondrial dysfunction, decreases in active Na+ transport, and cisplatin-induced apoptosis in renal cells. The Journal of biological chemistry. 2002 Nov; 277(45):43377-88. doi: 10.1074/jbc.m206373200. [PMID: 12218054]
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  • Xiaokang Ge, Ya-Min Fu, Yi-Qi Li, Gary G Meadows. Activation of caspases and cleavage of Bid are required for tyrosine and phenylalanine deficiency-induced apoptosis of human A375 melanoma cells. Archives of biochemistry and biophysics. 2002 Jul; 403(1):50-8. doi: 10.1016/s0003-9861(02)00211-4. [PMID: 12061801]
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  • Xiao-Fang Fei, Ben-Xiang Wang, Shinichi Tashiro, Tie-Jin Li, Ji-Sheng Ma, Takashi Ikejima. Apoptotic effects of ginsenoside Rh2 on human malignant melanoma A375-S2 cells. Acta pharmacologica Sinica. 2002 Apr; 23(4):315-22. doi: . [PMID: 11931705]
  • V Y Wong, P M Keller, M E Nuttall, K Kikly, W E DeWolf, D Lee, S M Ali, D P Nadeau, E T Grygielko, N J Laping, D P Brooks. Role of caspases in human renal proximal tubular epithelial cell apoptosis. European journal of pharmacology. 2001 Dec; 433(2-3):135-40. doi: 10.1016/s0014-2999(01)01517-5. [PMID: 11755144]
  • R Anjum, A Khar. Differential regulation of apoptosis in AK-5 tumor cells by the proto-oncogene Bcl-2: presence of Bcl-2 dependent and independent pathways. FEBS letters. 2001 Jun; 499(1-2):166-70. doi: 10.1016/s0014-5793(01)02543-1. [PMID: 11418133]
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  • S Camandola, G Poli, M P Mattson. The lipid peroxidation product 4-hydroxy-2,3-nonenal increases AP-1-binding activity through caspase activation in neurons. Journal of neurochemistry. 2000 Jan; 74(1):159-68. doi: 10.1046/j.1471-4159.2000.0740159.x. [PMID: 10617117]
  • S H Inayat-Hussain, A B Osman, L B Din, A M Ali, R T Snowden, M MacFarlane, K Cain. Caspases-3 and -7 are activated in goniothalamin-induced apoptosis in human Jurkat T-cells. FEBS letters. 1999 Aug; 456(3):379-83. doi: 10.1016/s0014-5793(99)00984-9. [PMID: 10462048]
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