2,4-Pentadienoic acid, 3-methyl-5-((1S,2S)-2-methyl-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)cyclopropyl)-, (2E,4E)- (BioDeep_00000838281)
代谢物信息卡片
化学式: C24H32O2 (352.2402)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=CC(=O)O)C=CC1CC1(C)C2=CC3=C(C=C2)C(CCC3(C)C)(C)C
InChI: InChI=1S/C24H32O2/c1-16(13-21(25)26)7-8-18-15-24(18,6)17-9-10-19-20(14-17)23(4,5)12-11-22(19,2)3/h7-10,13-14,18H,11-12,15H2,1-6H3,(H,25,26)/b8-7+,16-13+/t18-,24-/m1/s1
描述信息
C274 - Antineoplastic Agent > C2122 - Cell Differentiating Agent > C1934 - Differentiation Inducer
C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C804 - Retinoic Acid Agent
C308 - Immunotherapeutic Agent > C129820 - Antineoplastic Immunomodulating Agent
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Keiyu Oshida, Naresh Vasani, Russell S Thomas, Dawn Applegate, Mitch Rosen, Barbara Abbott, Christopher Lau, Grace Guo, Lauren M Aleksunes, Curtis Klaassen, J Christopher Corton. Identification of modulators of the nuclear receptor peroxisome proliferator-activated receptor α (PPARα) in a mouse liver gene expression compendium.
PloS one.
2015; 10(2):e0112655. doi:
10.1371/journal.pone.0112655. [PMID: 25689681] - Bingrong Liu, Kuk-Wha Lee, Heju Li, Liqun Ma, George L Lin, Roshantha A S Chandraratna, Pinchas Cohen. Combination therapy of insulin-like growth factor binding protein-3 and retinoid X receptor ligands synergize on prostate cancer cell apoptosis in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2005 Jul; 11(13):4851-6. doi:
10.1158/1078-0432.ccr-04-2160. [PMID: 16000583] - J Christopher Corton, Udayan Apte, Steven P Anderson, Pallavi Limaye, Lawrence Yoon, John Latendresse, Corrie Dunn, Jeffrey I Everitt, Kenneth A Voss, Cynthia Swanson, Carie Kimbrough, Jean S Wong, Sarjeet S Gill, Roshantha A S Chandraratna, Mi-Kyoung Kwak, Thomas W Kensler, Thomas M Stulnig, Knut R Steffensen, Jan-Ake Gustafsson, Harihara M Mehendale. Mimetics of caloric restriction include agonists of lipid-activated nuclear receptors.
The Journal of biological chemistry.
2004 Oct; 279(44):46204-12. doi:
10.1074/jbc.m406739200. [PMID: 15302862] - Matthias Schaier, Sabine Liebler, Kerstin Schade, Fujio Shimizu, Hiroshi Kawachi, Hermann-Joseph Grone, Roshantha Chandraratna, Eberhard Ritz, Juergen Wagner. Retinoic acid receptor alpha and retinoid X receptor specific agonists reduce renal injury in established chronic glomerulonephritis of the rat.
Journal of molecular medicine (Berlin, Germany).
2004 Feb; 82(2):116-25. doi:
10.1007/s00109-003-0510-3. [PMID: 14712350] - Karine Hellemans, Krista Rombouts, Erik Quartier, Andrea S Dittié, Andreas Knorr, Liliane Michalik, Vera Rogiers, Frans Schuit, Walter Wahli, Andrea Geerts. PPARbeta regulates vitamin A metabolism-related gene expression in hepatic stellate cells undergoing activation.
Journal of lipid research.
2003 Feb; 44(2):280-95. doi:
10.1194/jlr.m200376-jlr200. [PMID: 12576510] - Paolo E Macchia, Ping Jiang, Yan-Dar Yuan, Roshantha A S Chandarardna, Roy E Weiss, Olivier Chassande, Jacques Samarut, Samuel Refetoff, Charles F Burant. RXR receptor agonist suppression of thyroid function: central effects in the absence of thyroid hormone receptor.
American journal of physiology. Endocrinology and metabolism.
2002 Aug; 283(2):E326-31. doi:
10.1152/ajpendo.00313.2001. [PMID: 12110538] - A M Standeven, S M Thacher, Y D Yuan, M Escobar, V Vuligonda, R L Beard, R A Chandraratna. Retinoid X receptor agonist elevation of serum triglycerides in rats by potentiation of retinoic acid receptor agonist induction or by action as single agents.
Biochemical pharmacology.
2001 Dec; 62(11):1501-9. doi:
10.1016/s0006-2952(01)00803-6. [PMID: 11728386] - D Alsop, S Brown, G Van Der Kraak. Development of a retinoic acid receptor-binding assay with rainbow trout tissue: characterization of retinoic acid binding, receptor tissue distribution, and developmental changes.
General and comparative endocrinology.
2001 Sep; 123(3):254-67. doi:
10.1006/gcen.2001.7659. [PMID: 11589627]
