Nona-arginine (BioDeep_00000838194)
代谢物信息卡片
化学式: C54H110N36O10 (1422.92052)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(CC(C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCCN=C(N)N)C(=O)O)N)CN=C(N)N
InChI: InChI=1S/C54H110N36O10/c55-28(10-1-19-74-46(56)57)37(91)83-29(11-2-20-75-47(58)59)38(92)84-30(12-3-21-76-48(60)61)39(93)85-31(13-4-22-77-49(62)63)40(94)86-32(14-5-23-78-50(64)65)41(95)87-33(15-6-24-79-51(66)67)42(96)88-34(16-7-25-80-52(68)69)43(97)89-35(17-8-26-81-53(70)71)44(98)90-36(45(99)100)18-9-27-82-54(72)73/h28-36H,1-27,55H2,(H,83,91)(H,84,92)(H,85,93)(H,86,94)(H,87,95)(H,88,96)(H,89,97)(H,90,98)(H,99,100)(H4,56,57,74)(H4,58,59,75)(H4,60,61,76)(H4,62,63,77)(H4,64,65,78)(H4,66,67,79)(H4,68,69,80)(H4,70,71,81)(H4,72,73,82)
数据库引用编号
5 个数据库交叉引用编号
- PubChem: 25077438
- PubChem: 25074997
- DrugBank: DB12648
- ChEMBL: CHEMBL4090674
- CAS: 143413-47-2
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Claudia Almeida, Ofelia Maniti, Margherita Di Pisa, Jean-Marie Swiecicki, Jesus Ayala-Sanmartin. Cholesterol re-organisation and lipid de-packing by arginine-rich cell penetrating peptides: Role in membrane translocation.
PloS one.
2019; 14(1):e0210985. doi:
10.1371/journal.pone.0210985
. [PMID: 30673771] - Ji Hee Kang, Gantumur Battogtokh, Young Tag Ko. Self-Assembling Lipid-Peptide Hybrid Nanoparticles of Phospholipid-Nonaarginine Conjugates for Enhanced Delivery of Nucleic Acid Therapeutics.
Biomacromolecules.
2017 Nov; 18(11):3733-3741. doi:
10.1021/acs.biomac.7b01084
. [PMID: 28954191] - Marco J Klein, Samuel Schmidt, Parvesh Wadhwani, Jochen Bürck, Johannes Reichert, Sergii Afonin, Marina Berditsch, Tim Schober, Roland Brock, Manfred Kansy, Anne S Ulrich. Lactam-Stapled Cell-Penetrating Peptides: Cell Uptake and Membrane Binding Properties.
Journal of medicinal chemistry.
2017 10; 60(19):8071-8082. doi:
10.1021/acs.jmedchem.7b00813
. [PMID: 28921993] - Sabrina Sharmin, Md Zahidul Islam, Mohammad Abu Sayem Karal, Sayed Ul Alam Shibly, Hideo Dohra, Masahito Yamazaki. Effects of Lipid Composition on the Entry of Cell-Penetrating Peptide Oligoarginine into Single Vesicles.
Biochemistry.
2016 08; 55(30):4154-65. doi:
10.1021/acs.biochem.6b00189
. [PMID: 27420912] - Janely Pae, Laura Liivamägi, Dmitri Lubenets, Piret Arukuusk, Ülo Langel, Margus Pooga. Glycosaminoglycans are required for translocation of amphipathic cell-penetrating peptides across membranes.
Biochimica et biophysica acta.
2016 08; 1858(8):1860-7. doi:
10.1016/j.bbamem.2016.04.010
. [PMID: 27117133] - Kamran Melikov, Ann Hara, Kwabena Yamoah, Elena Zaitseva, Eugene Zaitsev, Leonid V Chernomordik. Efficient entry of cell-penetrating peptide nona-arginine into adherent cells involves a transient increase in intracellular calcium.
The Biochemical journal.
2015 Oct; 471(2):221-30. doi:
10.1042/bj20150272
. [PMID: 26272944] - Ziqing Qian, Jonathan R LaRochelle, Bisheng Jiang, Wenlong Lian, Ryan L Hard, Nicholas G Selner, Rinrada Luechapanichkul, Amy M Barrios, Dehua Pei. Early endosomal escape of a cyclic cell-penetrating peptide allows effective cytosolic cargo delivery.
Biochemistry.
2014 Jun; 53(24):4034-46. doi:
10.1021/bi5004102
. [PMID: 24896852] - Jingjing Zhu, Jeroen Declercq, Bart Roucourt, Gholamreza H Ghassabeh, Sandra Meulemans, Jörg Kinne, Guido David, Alphons J M Vermorken, Wim J M Van de Ven, Iris Lindberg, Serge Muyldermans, John W M Creemers. Generation and characterization of non-competitive furin-inhibiting nanobodies.
The Biochemical journal.
2012 Nov; 448(1):73-82. doi:
10.1042/bj20120537
. [PMID: 22920187] - Yi Xu, Betty Revon Liu, Han-Jung Lee, Katie B Shannon, Jeffrey G Winiarz, Tien-Chun Wang, Huey-Jenn Chiang, Yue-wern Huang. Nona-arginine facilitates delivery of quantum dots into cells via multiple pathways.
Journal of biomedicine & biotechnology.
2010; 2010(?):948543. doi:
10.1155/2010/948543
. [PMID: 21048930]