Gallium maltolate (BioDeep_00000838179)
代谢物信息卡片
化学式: C18H15GaO9 (443.99718500000006)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(C(=O)C=CO1)[O-].CC1=C(C(=O)C=CO1)[O-].CC1=C(C(=O)C=CO1)[O-].[Ga+3]
InChI: /q
描述信息
C78275 - Agent Affecting Blood or Body Fluid > C2136 - Malignancy-Associated Hypercalcemia Inhibitor
C78281 - Agent Affecting Musculoskeletal System > C67439 - Bone Resorption Inhibitor
C471 - Enzyme Inhibitor > C2150 - Ribonucleotide Reductase Inhibitor
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- S Álvarez-Narváez, L J Berghaus, E R A Morris, J M Willingham-Lane, N M Slovis, S Giguere, N D Cohen. A Common Practice of Widespread Antimicrobial Use in Horse Production Promotes Multi-Drug Resistance.
Scientific reports.
2020 01; 10(1):911. doi:
10.1038/s41598-020-57479-9. [PMID: 31969575] - Lawrence R Bernstein, Leike Zhang. Gallium maltolate has in vitro antiviral activity against SARS-CoV-2 and is a potential treatment for COVID-19.
Antiviral chemistry & chemotherapy.
2020 Jan; 28(?):2040206620983780. doi:
10.1177/2040206620983780. [PMID: 33353394] - Caroline S Monk, Raymond W Sweeney, Lawrence R Bernstein, Marie-Eve Fecteau. Serum and tissue concentrations of gallium after oral administration of gallium nitrate and gallium maltolate to neonatal calves.
American journal of veterinary research.
2016 Feb; 77(2):151-5. doi:
10.2460/ajvr.77.2.151. [PMID: 27027708] - Éva A Enyedy, Orsolya Dömötör, Krisztina Bali, Anasztázia Hetényi, Tiziano Tuccinardi, Bernhard K Keppler. Interaction of the anticancer gallium(III) complexes of 8-hydroxyquinoline and maltol with human serum proteins.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry.
2015 Jan; 20(1):77-88. doi:
10.1007/s00775-014-1211-9. [PMID: 25398250] - F Sampieri, A L Allen, J Alcorn, C R Clark, F A Vannucci, N Pusterla, S M Mapes, K R Ball, P M Dowling, J Thompson, L R Bernstein, C J Gebhart, D L Hamilton. Efficacy of gallium maltolate against Lawsonia intracellularis infection in a rabbit model.
Journal of veterinary pharmacology and therapeutics.
2014 Dec; 37(6):571-8. doi:
10.1111/jvp.12132. [PMID: 24730377] - F Sampieri, J Alcorn, A L Allen, C R Clark, F A Vannucci, N Pusterla, S Mapes, K R Ball, P M Dowling, J Thompson, L R Bernstein, C J Gebhart, D L Hamilton. Pharmacokinetics of gallium maltolate in Lawsonia intracellularis-infected and uninfected rabbits.
Journal of veterinary pharmacology and therapeutics.
2014 Oct; 37(5):486-99. doi:
10.1111/jvp.12114. [PMID: 24628462] - G F Pollina, M Pepe, A Dean, V Di Marco, D Marton. Reduction in absorption of gallium maltolate in adult horses following oral administration with food: chemistry and pharmacokinetics.
Journal of veterinary pharmacology and therapeutics.
2013 Oct; 36(5):456-61. doi:
10.1111/jvp.12022. [PMID: 23980593] - Lawrence R Bernstein, Jacobus J M van der Hoeven, Robbert O Boer. Hepatocellular carcinoma detection by gallium scan and subsequent treatment by gallium maltolate: rationale and case study.
Anti-cancer agents in medicinal chemistry.
2011 Jul; 11(6):585-90. doi:
10.2174/187152011796011046. [PMID: 21554205] - J R Nerren, T S Edrington, L R Bernstein, R L Farrow, K G Genovese, T R Callaway, R C Anderson, N A Krueger, S E Duke, D J Nisbet. Evaluation of the effect of gallium maltolate on fecal Salmonella shedding in cattle.
Journal of food protection.
2011 Apr; 74(4):524-30. doi:
10.4315/0362-028x.jfp-10-298. [PMID: 21477464] - Carolyn Arnold, M Keith Chaffin, Noah Cohen, Virginia R Fajt, Robert J Taylor, Lawrence R Bernstein. Pharmacokinetics of gallium maltolate after intragastric administration in adult horses.
American journal of veterinary research.
2010 Nov; 71(11):1371-6. doi:
10.2460/ajvr.71.11.1371. [PMID: 21034329] - M K Chaffin, V Fajt, R J Martens, C E Arnold, N D Cohen, M O'Conor, R J Taylor, L R Bernstein. Pharmacokinetics of an orally administered methylcellulose formulation of gallium maltolate in neonatal foals.
Journal of veterinary pharmacology and therapeutics.
2010 Aug; 33(4):376-82. doi:
10.1111/j.1365-2885.2009.01150.x. [PMID: 20646200] - Ronald J Martens, Katrina Mealey, Noah D Cohen, Jessica R Harrington, M Keith Chaffin, Robert J Taylor, Lawrence R Bernstein. Pharmacokinetics of gallium maltolate after intragastric administration in neonatal foals.
American journal of veterinary research.
2007 Oct; 68(10):1041-4. doi:
10.2460/ajvr.68.10.1041. [PMID: 17916007]