Ginsenosides (BioDeep_00000838165)
代谢物信息卡片
Ginsenosides
化学式: C30H52O2 (444.3967)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=CCCC(C)(C1CCC2(C1CCC3C2(CCC4C3(CCC(C4(C)C)O)C)C)C)O)C
InChI: InChI=1S/C30H52O2/c1-20(2)10-9-16-30(8,32)22-13-18-28(6)21(22)11-12-24-27(5)17-15-25(31)26(3,4)23(27)14-19-29(24,28)7/h10,21-25,31-32H,9,11-19H2,1-8H3/t21?,22-,23-,24+,25-,27-,28+,29+,30?/m0/s1
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Hui Ao, Huizhu Song, Jing Li, Xiangtao Wang. Enhanced anti-glioma activity of annonaceous acetogenins based on a novel liposomal co-delivery system with ginsenoside Rh2.
Drug delivery.
2024 Dec; 31(1):2324716. doi:
10.1080/10717544.2024.2324716. [PMID: 38555735] - Liangliang Kong, Yan Liu, Jingwei Li, Yanyan Wang, Pengmin Ji, Qifeng Shi, Min Han, Hanyang Xu, Weiping Li, Weizu Li. Ginsenoside Rg1 alleviates chronic inflammation-induced neuronal ferroptosis and cognitive impairments via regulation of AIM2 - Nrf2 signaling pathway.
Journal of ethnopharmacology.
2024 Aug; 330(?):118205. doi:
10.1016/j.jep.2024.118205. [PMID: 38641079] - Hui Liu, Xiao-Qian Wu, Xiang-Ling Qin, Jin-Hao Zhu, Jin-Di Xu, Shan-Shan Zhou, Ming Kong, Hong Shen, Jie-Ge Huo, Song-Lin Li, He Zhu. Metals/bisulfite system involved generation of 24-sulfonic-25-ene ginsenoside Rg1, a potential quality control marker for sulfur-fumigated ginseng.
Food chemistry.
2024 Aug; 448(?):139112. doi:
10.1016/j.foodchem.2024.139112. [PMID: 38569404] - Linlin Liu, Mozhu Jin, Xueying Han, Deqiang Dou. Identifying biomarkers of ginseng medicines with different natures on heart failure.
Journal of ethnopharmacology.
2024 Jul; 329(?):118134. doi:
10.1016/j.jep.2024.118134. [PMID: 38574777] - Mengge Shi, Han Han, Li Yang, Zhengtao Wang, Kaixian Chen. Development and validation of a dried blood spots assay for metabolic profiling of ginsenosides using ultra-high performance liquid chromatography-mass spectrometry.
Journal of ethnopharmacology.
2024 Jul; 329(?):118136. doi:
10.1016/j.jep.2024.118136. [PMID: 38583731] - Rui Liu, Li-Xia Xu, Lin-Jian Tong, Hai-Yang Wu, Qiang Guo, Zhi-Ming Sun, Hua Yan. Therapeutic effects of ginsenosides on osteoporosis for novel drug applications.
European journal of pharmacology.
2024 Jul; 974(?):176604. doi:
10.1016/j.ejphar.2024.176604. [PMID: 38649090] - Louyin Ji, Hui Han, Xiaoli Shan, Pei Zhao, Huihua Chen, Chen Zhang, Ming Xu, Rong Lu, Wei Guo. Ginsenoside Rb1 ameliorates lipotoxicity-induced myocardial injury in diabetes mellitus by regulating Mfn2.
European journal of pharmacology.
2024 Jul; 974(?):176609. doi:
10.1016/j.ejphar.2024.176609. [PMID: 38677536] - Ying Liu, Xinran Wang, Chenrong Jin, Juhui Qiao, Chenxi Wang, Leilei Jiang, Shiting Yu, Daian Pan, Daqing Zhao, Siming Wang, Meichen Liu. Total ginsenosides extend healthspan of aging Drosophila by suppressing imbalances in intestinal stem cells and microbiota.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Jul; 129(?):155650. doi:
10.1016/j.phymed.2024.155650. [PMID: 38669971] - Longchan Liu, Wenxiang Fan, Haoyue Zhang, Linhong Fan, Yuqi Mei, Ziying Wang, Linnan Li, Li Yang, Zhengtao Wang. A versatile economic strategy by HPLC-CAD for quantification of structurally diverse markers in quality control of Shengmai Formula from raw materials to preparations.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Jul; 129(?):155625. doi:
10.1016/j.phymed.2024.155625. [PMID: 38692077] - Panpan Zhao, Ping Cheng, Jingji Wang, Guoqi Zhu, Xuncui Wang. Shenqi Yizhi prescription prevents AβO-induced memory impairment in mice by regulating the contractility of brain pericytes.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Jul; 129(?):155639. doi:
10.1016/j.phymed.2024.155639. [PMID: 38669966] - Guoqing Zhang, Jinpeng Hu, Ao Li, Haiying Zhang, Zhengting Guo, Xinqiao Li, Zinan You, Yongfeng Wang, Zhitao Jing. Ginsenoside Rg5 inhibits glioblastoma by activating ferroptosis via NR3C1/HSPB1/NCOA4.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Jul; 129(?):155631. doi:
10.1016/j.phymed.2024.155631. [PMID: 38640858] - An-Qi Wang, Ya-Jie Wang, Jing Zhang, Yi-Ming Fan, Shi-Yang Li, Li-Wei Zou. Comparative study on inhibitory effects of ginsenosides on human pancreatic lipase and porcine pancreatic lipase: structure-activity relationships and inhibitory mechanism.
Natural product research.
2024 Jun; 38(12):2031-2039. doi:
10.1080/14786419.2023.2235713. [PMID: 37471672] - Shuxia Zhang, Qiuyan Chen, Meiqi Jin, Jiahui Ren, Xiao Sun, Zhixiu Zhang, Yun Luo, Xiaobo Sun. Notoginsenoside R1 alleviates cerebral ischemia/reperfusion injury by inhibiting the TLR4/MyD88/NF-κB signaling pathway through microbiota-gut-brain axis.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Jun; 128(?):155530. doi:
10.1016/j.phymed.2024.155530. [PMID: 38493723] - Yun Wang, Jiawei Wu, Yu Hong, Jiaying Zhu, Youcai Zhang, Jun Zhang, Chujie Ding, Yuan Che, Guangji Wang, Aiqin Jiang, Haiping Hao, Lijuan Cao. Ginsenosides retard atherogenesis via remodelling host-microbiome metabolic homeostasis.
British journal of pharmacology.
2024 Jun; 181(12):1768-1792. doi:
10.1111/bph.16320. [PMID: 38355288] - Honoka Ito, Michiho Ito. Recent trends in ginseng research.
Journal of natural medicines.
2024 Jun; 78(3):455-466. doi:
10.1007/s11418-024-01792-4. [PMID: 38512649] - Jingyue Yu, Jinyu Hu, Margaret Baldini, Huan Lei, Lei Li, Shanshan Luo, Jielian Wu, Xupin Liu, Dan Shan, Yanfei Xie, Haihong Fang, Jun Yu. Integrating network pharmacology and experimental models to identify notoginsenoside R1 ameliorates atherosclerosis by inhibiting macrophage NLRP3 inflammasome activation.
Journal of natural medicines.
2024 Jun; 78(3):644-654. doi:
10.1007/s11418-023-01776-w. [PMID: 38409483] - Yafei Zhai, Jinmeng Bai, Ying Peng, Jinhua Cao, Guangming Fang, Yiming Dong, Ze Wang, Yanyu Lu, Mengyu Wang, Mengduan Liu, Yangyang Liu, Xiaowei Li, Jianzeng Dong, Xiaoyan Zhao. Ginsenoside Rb1 attenuates doxorubicin induced cardiotoxicity by suppressing autophagy and ferroptosis.
Biochemical and biophysical research communications.
2024 May; 710(?):149910. doi:
10.1016/j.bbrc.2024.149910. [PMID: 38593619] - Feiyan Tao, Qingfeng Zhai, Yuqing Cao, Hui Gao, Yuqing Cai, Wenjing Jia, Huagang Ma, Peng Xue. Inhibition of p38 MAPK/NF-κB p65 signaling pathway activity by rare ginsenosides ameliorates cyclophosphamide-induced premature ovarian failure and KGN cell injury.
Journal of ethnopharmacology.
2024 May; 326(?):117944. doi:
10.1016/j.jep.2024.117944. [PMID: 38382656] - Lingchao Miao, Yan Zhou, Dechao Tan, Chunxiu Zhou, Cheng-Chao Ruan, Shengpeng Wang, Yitao Wang, Chi Teng Vong, Wai San Cheang. Ginsenoside Rk1 improves endothelial function in diabetes through activating peroxisome proliferator-activated receptors.
Food & function.
2024 May; 15(10):5485-5495. doi:
10.1039/d3fo05222b. [PMID: 38690748] - Shulei Zhang, Bo Zheng, Yiqi Wei, Yuhao Liu, Lan Yang, Yujiao Qiu, Jing Su, Mingfeng Qiu. Bioinspired ginsenoside Rg3 PLGA nanoparticles coated with tumor-derived microvesicles to improve chemotherapy efficacy and alleviate toxicity.
Biomaterials science.
2024 May; 12(10):2672-2688. doi:
10.1039/d4bm00159a. [PMID: 38596867] - Cuihan Zhang, Huan Hou, Changhong Shen, Qian Ran, Fang Cheng, Ziqing Yao, Ruoqi Zhang, Cheng Peng. Protective effect of ginsenoside Rb1 against aconitine cardiotoxicity studied by myocardial injury, action potential, and calcium signaling.
Toxicon : official journal of the International Society on Toxinology.
2024 May; 242(?):107693. doi:
10.1016/j.toxicon.2024.107693. [PMID: 38519012] - Xue-Ting Zhao, De-Qiang Dou, Yang Qu, Guo-Gang Zhang. Structure elucidation and NMR spectral assignments of one new dammarane-type triterpenoid saponin from black ginseng.
Journal of Asian natural products research.
2024 May; 26(5):636-643. doi:
10.1080/10286020.2023.2253153. [PMID: 37681976] - Hongda Wang, Lin Zhang, Xiaohang Li, Mengxiao Sun, Meiting Jiang, Xiaojian Shi, Xiaoyan Xu, Mengxiang Ding, Boxue Chen, Heshui Yu, Zheng Li, Dean Guo, Wenzhi Yang. Machine learning prediction for constructing a universal multidimensional information library of Panax saponins (ginsenosides).
Food chemistry.
2024 May; 439(?):138106. doi:
10.1016/j.foodchem.2023.138106. [PMID: 38056336] - Zhiqiang Niu, Yanan Liu, Ruyi Shen, Xiaojian Jiang, Yanting Wang, Ziliang He, Junyao Li, Yeye Hu, Ji Zhang, Yunyao Jiang, Weicheng Hu, Chuanling Si, Shuai Wei, Ting Shen. Ginsenosides from Panax ginseng as potential therapeutic candidates for the treatment of inflammatory bowel disease.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 May; 127(?):155474. doi:
10.1016/j.phymed.2024.155474. [PMID: 38471369] - Junyi Li, Min Lin, Zexin Xie, Liwenyu Chen, Jin Qi, Boyang Yu. Target Cell Extraction and Spectrum-Effect Relationship Coupled with BP Neural Network Classification for Screening Potential Bioactive Components in Ginseng Extract with a Protective Effect against Myocardial Damage.
Molecules (Basel, Switzerland).
2024 Apr; 29(9):. doi:
10.3390/molecules29092028. [PMID: 38731522] - Ruiqi Liu, Bin Zhang, Shuting Zou, Li Cui, Lin Lin, Lingchang Li. Ginsenoside Rg1 Induces Autophagy in Colorectal Cancer through Inhibition of the Akt/mTOR/p70S6K Pathway.
Journal of microbiology and biotechnology.
2024 Apr; 34(4):774-782. doi:
10.4014/jmb.2310.10043. [PMID: 38668684] - Xiyu Liu, Jingjing Li, Qingqing Huang, Mingming Jin, Gang Huang. Ginsenoside Rh2 shifts tumor metabolism from aerobic glycolysis to oxidative phosphorylation through regulating the HIF1-α/PDK4 axis in non-small cell lung cancer.
Molecular medicine (Cambridge, Mass.).
2024 Apr; 30(1):56. doi:
10.1186/s10020-024-00813-y. [PMID: 38671369] - Xiaoxuan Yuan, Ruiqiong Li, Weishen He, Wei Xu, Wen Xu, Guohong Yan, Shaohua Xu, Lixia Chen, Yaqian Feng, Hua Li. Progress in Identification of UDP-Glycosyltransferases for Ginsenoside Biosynthesis.
Journal of natural products.
2024 Apr; 87(4):1246-1267. doi:
10.1021/acs.jnatprod.3c00630. [PMID: 38449105] - Jiaxin Chen, Zhuoshi Wang, Jinghao Fu, Yuesong Cai, Haoyi Cheng, Xinmu Cui, Manqing Sun, Mingyue Liu, Xuewu Zhang. Ginsenoside compound K induces ferroptosis via the FOXO pathway in liver cancer cells.
BMC complementary medicine and therapies.
2024 Apr; 24(1):174. doi:
10.1186/s12906-024-04471-9. [PMID: 38664638] - Subecha Rai, Laishram Shantikumar Singh, Ramanan Uma Shaanker, Kumaraswamy Jeyaram, Tithi Parija, Dinabandhu Sahoo. Endophytic fungi of Panax sokpayensis produce bioactive ginsenoside Compound K in flask fermentation.
Scientific reports.
2024 04; 14(1):9318. doi:
10.1038/s41598-024-56441-3. [PMID: 38654024] - Fang Feng, Hyun-A Ko, Thi My Tien Truong, Woo-Jin Song, Eun-Ju Ko, Inhae Kang. Ginsenoside Rg3, enriched in red ginseng extract, improves lipopolysaccharides-induced suppression of brown and beige adipose thermogenesis with mitochondrial activation.
Scientific reports.
2024 04; 14(1):9157. doi:
10.1038/s41598-024-59758-1. [PMID: 38644456] - Tingting Zhou, Qiong Li, Xin Huang, Changbao Chen. Analysis Transcriptome and Phytohormone Changes Associated with the Allelopathic Effects of Ginseng Hairy Roots Induced by Different-Polarity Ginsenoside Components.
Molecules (Basel, Switzerland).
2024 Apr; 29(8):. doi:
10.3390/molecules29081877. [PMID: 38675697] - Mei Tong He, Geonha Park, Do Hwi Park, Minsik Choi, Sejin Ku, Seung Hyeon Go, Yun Gyo Lee, Seok Jun Song, Chang-Wook Ahn, Young Pyo Jang, Ki Sung Kang. So Shiho Tang Reduces Inflammation in Lipopolysaccharide-Induced RAW 264.7 Macrophages and Dextran Sodium Sulfate-Induced Colitis Mice.
Biomolecules.
2024 Apr; 14(4):. doi:
10.3390/biom14040451. [PMID: 38672468] - Yingqiu Shi, Haoran Li, Yugang Lin, Shufang Wang, Guofang Shen. Effective constituents and protective effect of Mudan granules against Schwann cell injury.
Journal of ethnopharmacology.
2024 Apr; 323(?):117692. doi:
10.1016/j.jep.2023.117692. [PMID: 38176668] - Zongzhan Wu, Wenyu Dou, Xiaolin Yang, Tengfei Niu, Zhuzhen Han, Li Yang, Rufeng Wang, Zhengtao Wang. Novel glycosidase from Paenibacillus lactis 154 hydrolyzing the 28-O-β-D-glucopyranosyl ester bond of oleanane-type saponins.
Applied microbiology and biotechnology.
2024 Apr; 108(1):282. doi:
10.1007/s00253-024-13109-2. [PMID: 38573330] - Xufan Cai, Zhaohong Wang, Shengzhang Lin, Hui Chen, Heqi Bu. Ginsenoside Rg3 suppresses vasculogenic mimicry by impairing DVL3-maintained stemness via PAAD cell-derived exosomal miR-204 in pancreatic adenocarcinoma.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Apr; 126(?):155402. doi:
10.1016/j.phymed.2024.155402. [PMID: 38350242] - Cheng Guo, Linying Lai, Boyu Ma, Qian Huang, Zhirong Wang. Notoginsenoside R1 targets PPAR-γ to inhibit hepatic stellate cell activation and ameliorates liver fibrosis.
Experimental cell research.
2024 Apr; 437(1):113992. doi:
10.1016/j.yexcr.2024.113992. [PMID: 38492634] - Zhuo-Yao Li, Yu-Xiang Dai, Zi-Ming Wu, Gan Li, Pei-Min Pu, Cai-Wei Hu, Long-Yun Zhou, Ke Zhu, Bing Shu, Yong-Jun Wang, Xue-Jun Cui, Min Yao. Network pharmacology analysis and animal experiment validation of neuroinflammation inhibition by total ginsenoside in treating CSM.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Apr; 126(?):155073. doi:
10.1016/j.phymed.2023.155073. [PMID: 38417244] - Yutao Feng, Yuan Li, Fen Ma, Enjiang Wu, Zewei Cheng, Shiling Zhou, Zhengtao Wang, Li Yang, Xun Sun, Jiwei Zhang. Notoginsenoside Ft1 inhibits colorectal cancer growth by increasing CD8+ T cell proportion in tumor-bearing mice through the USP9X signaling pathway.
Chinese journal of natural medicines.
2024 Apr; 22(4):329-340. doi:
10.1016/s1875-5364(24)60623-0. [PMID: 38658096] - Wenjing Yu, Siyuan Cai, Jiali Zhao, Shuhan Hu, Chen Zang, Jiang Xu, Lianghai Hu. Beyond genome: Advanced omics progress of Panax ginseng.
Plant science : an international journal of experimental plant biology.
2024 Apr; 341(?):112022. doi:
10.1016/j.plantsci.2024.112022. [PMID: 38311250] - Meiyu Cui, Zakia Fatima, Zhao Wang, Yang Lei, Xiangai Zhao, Mingshi Jin, Lu Liu, Chunyu Yu, Meihui Tong, Donghao Li. Specific fractionation of ginsenosides based on activated carbon fibers and online fast screening of ginseng extract by mass spectrometry.
Journal of chromatography. A.
2024 Mar; 1719(?):464774. doi:
10.1016/j.chroma.2024.464774. [PMID: 38422707] - Lianjie Hou, Zhiming Zou, Yu Wang, Hui Pi, Zeyue Yuan, Qin He, Yongfang Kuang, Guojun Zhao. Exploring the anti-atherosclerosis mechanism of ginsenoside Rb1 by integrating network pharmacology and experimental verification.
Aging.
2024 Mar; 16(8):6745-6756. doi:
10.18632/aging.205680. [PMID: 38546402] - Huijeong Ahn, Geun-Shik Lee. Amino Sugar-Enriched Fraction of Korean Red Ginseng Extract Induces the Priming Step of NLRP3 Inflammasome.
Molecules (Basel, Switzerland).
2024 Mar; 29(7):. doi:
10.3390/molecules29071455. [PMID: 38611734] - Chunhou Li, Xican Li, Jingyuan Zeng, Rongxin Cai, Shaoman Chen, Ban Chen, Xiaojun Zhao. Detection of Adulterated Naodesheng Tablet (Naodesheng Pian) via In-Depth Chemical Analysis and Subsequent Reconstruction of Its Pharmacopoeia Q-Markers.
Molecules (Basel, Switzerland).
2024 Mar; 29(6):. doi:
10.3390/molecules29061392. [PMID: 38543029] - Yingying Shi, Jianbo Chen, Di Qu, Qiang Sun, Yang Yu, Hao Zhang, Zhengbo Liu, Jiyue Sha, Yinshi Sun. Ginsenoside Rg5 Activates the LKB1/AMPK/mTOR Signaling Pathway and Modifies the Gut Microbiota to Alleviate Nonalcoholic Fatty Liver Disease Induced by a High-Fat Diet.
Nutrients.
2024 Mar; 16(6):. doi:
10.3390/nu16060842. [PMID: 38542753] - Yang Jiang, Qi Zhang, Zixia Zeng, Yi Wang, Mingzhu Zhao, Kangyu Wang, Meiping Zhang. The AP2/ERF Transcription Factor PgERF120 Regulates Ginsenoside Biosynthesis in Ginseng.
Biomolecules.
2024 Mar; 14(3):. doi:
10.3390/biom14030345. [PMID: 38540764] - Md Niaj Morshed, Md Rezaul Karim, Reshmi Akter, Safia Iqbal, Ramya Mathiyalagan, Jong Chan Ahn, Deok Chun Yang, Joong Hyun Song, Se Chan Kang, Dong Uk Yang. Potential of Gut Microbial Metabolites in Treating Osteoporosis and Obesity: A Network Pharmacology and Bioinformatics Approach.
Medical science monitor : international medical journal of experimental and clinical research.
2024 Mar; 30(?):e942899. doi:
10.12659/msm.942899. [PMID: 38509819] - Lixia Tian, Ranran Gao, Yuxiang Cai, Junxian Chen, Hongmei Dong, Shanshan Chen, Zaichang Yang, Yu Wang, Linfang Huang, Zhichao Xu. A systematic review of ginsenoside biosynthesis, spatiotemporal distribution, and response to biotic and abiotic factors in American ginseng.
Food & function.
2024 Mar; 15(5):2343-2365. doi:
10.1039/d3fo03434h. [PMID: 38323507] - Yu-Shun Lu, Zheng-Bo Liu, Yan-Yang Xu, Ji-Yue Sha, Di Qu, Yin-Shi Sun. Uptake and accumulation of di(2-ethylhexyl) phthalate (DEHP) in a soil-ginseng system and toxicological mechanisms on ginseng (Panax ginseng C.A. Meyer).
The Science of the total environment.
2024 Mar; 914(?):170040. doi:
10.1016/j.scitotenv.2024.170040. [PMID: 38215853] - Habeeb Tajudeen, SangHun Ha, Abdolreza Hosseindoust, JunYoung Mun, Serin Park, Choi Pok Su, Elick Kinara, JinSoo Kim. The pharmaceutical effect of Korean wild ginseng residue extract on the performance, microbiota quality, cytokine expression, and the ginseng saponin content of laying hen.
Poultry science.
2024 Mar; 103(3):103467. doi:
10.1016/j.psj.2024.103467. [PMID: 38295502] - Kang-Xi Zhang, Yue Zhu, Shu-Xia Song, Qing-Yun Bu, Xiao-Yan You, Hong Zou, Guo-Ping Zhao. Ginsenoside Rb1, Compound K and 20(S)-Protopanaxadiol Attenuate High-Fat Diet-Induced Hyperlipidemia in Rats via Modulation of Gut Microbiota and Bile Acid Metabolism.
Molecules (Basel, Switzerland).
2024 Mar; 29(5):. doi:
10.3390/molecules29051108. [PMID: 38474620] - Hui-Zhi Li, Yan-Fang Zhao, Dai-Jie Wang, Hui-Juan Li, Ji-Xiang He, Xiang-Feng Chen. [Identification and visual analysis of ginsenosides in multi-steamed roots of Panax quinquefolium based on UPLC-Q-TOF-MS/MS and MALDI-MSI].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2024 Mar; 49(6):1526-1539. doi:
10.19540/j.cnki.cjcmm.20231211.301. [PMID: 38621936] - Nuan Lv, Luming Wang, Miao Zeng, Yijing Wang, Bin Yu, Wenyun Zeng, Xijuan Jiang, Yanrong Suo. Saponins as therapeutic candidates for atherosclerosis.
Phytotherapy research : PTR.
2024 Mar; 38(3):1651-1680. doi:
10.1002/ptr.8128. [PMID: 38299680] - JinFeng Liu, Ge Zhang, YuQing Wang, ZhuangZhuang Hao, JingWen Xue, YiFan Lu, WenXin Fan, ChunGuo Wang, JinLi Shi. Screening and verification of hemostatic effective components group of Panax Notoginseng based on spectrum-effect relationships.
Journal of ethnopharmacology.
2024 Mar; 321(?):117539. doi:
10.1016/j.jep.2023.117539. [PMID: 38056541] - Huandong Zhao, Ruimin Ding, Jiarui Han. Ginsenoside Rh4 Facilitates the Sensitivity of Renal Cell Carcinoma to Ferroptosis via the NRF2 Pathway.
Archivos espanoles de urologia.
2024 Mar; 77(2):119-128. doi:
10.56434/j.arch.esp.urol.20247702.16. [PMID: 38583003] - Baoyu Fu, Rui Ma, Fangbing Liu, Xuenan Chen, Manying Wang, Wenqi Jin, Shuai Zhang, Yanping Wang, Liwei Sun. New insights into ginsenoside Rg1 regulating the niche to inhibit age-induced germline stem cells depletion through targeting ECR/BMP signaling pathway in Drosophila.
Aging.
2024 Feb; 16(4):3612-3630. doi:
10.18632/aging.205548. [PMID: 38364249] - Juho Lim, Hayeong Kim, Gha-Hyun J Kim, Taeyoon Kim, Choon Gil Kang, Seung Wook Kim, Doman Kim. Enzymatic upcycling of wild-simulated ginseng leaves for enhancing biological activities and compound K.
Applied microbiology and biotechnology.
2024 Feb; 108(1):207. doi:
10.1007/s00253-024-13028-2. [PMID: 38353757] - Yanhuai Ma, Jianliang Li, Jiale Mai, Huizhi Guo, Lingli Ding, Jinglan Li, Jiacong Xiao, Miao Li, Weihua Fang, Shuncong Zhang, Liangliang Xu, Haibin Wang. Ginsenoside Rb2 exhibits therapeutic value for male osteoporosis in orchiectomy mice by suppressing osteoclastogenesis and modulating NF-κB/MAPK signaling pathways.
Food & function.
2024 Feb; 15(3):1583-1597. doi:
10.1039/d3fo04334g. [PMID: 38240189] - Ming-Yang Liu, Dong-Xin Jiang, Xiang Zhao, Liang Zhang, Yu Zhang, Zhen-Dong Liu, Run-Ze Liu, Hai-Jun Li, Xiao-Yu Rong, Yan-Zheng Gao. Exploration in the Mechanism of Ginsenoside Rg5 for the Treatment of Osteosarcoma by Network Pharmacology and Molecular Docking.
Orthopaedic surgery.
2024 Feb; 16(2):462-470. doi:
10.1111/os.13971. [PMID: 38086608] - Zhongjing Jiang, Linhua Deng, Mengjun Li, Emmanuel Alonge, Yanling Wang, Yunjia Wang. Ginsenoside Rg1 modulates PI3K/AKT pathway for enhanced osteogenesis via GPER.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Feb; 124(?):155284. doi:
10.1016/j.phymed.2023.155284. [PMID: 38176267] - Hoon Kim, Eun-Jin Jeong, Byungdoo Hwang, Hak-Dong Lee, Sanghyun Lee, Mi Jang, Kwangeun Yeo, Yunjeong Shin, Sanghoon Park, Wan Taek Lim, Woo Jung Kim, Sung-Kwon Moon. Pharmacological effects of biologically synthesized ginsenoside CK-rich preparation (AceCK40) on the colitis symptoms in DSS-induced Caco-2 cells and C57BL mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Feb; 124(?):155301. doi:
10.1016/j.phymed.2023.155301. [PMID: 38181531] - Weimin Wang, Hongwei Chen, Wenyuan Zhang, Daidi Fan, Jianjun Deng, Haixia Yang. Ginsenoside Rk3 Ameliorates Obesity-Induced Colitis by Modulating Lipid Metabolism in C57BL/6 Mice.
Journal of agricultural and food chemistry.
2024 Feb; ?(?):. doi:
10.1021/acs.jafc.3c08253. [PMID: 38300824] - Na Li, Chenhui Zhu, Rongzhan Fu, Xiaoxuan Ma, Zhiguang Duan, Daidi Fan. Ginsenoside Rg5 inhibits lipid accumulation and hepatocyte apoptosis via the Notch1 signaling pathway in NASH mice.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Feb; 124(?):155287. doi:
10.1016/j.phymed.2023.155287. [PMID: 38176268] - Yuhang Hu, Zhichao Lang, Xinmiao Li, Lifan Lin, Yifei Li, Rongrong Zhang, Jianjian Zheng, Zhengping Yu. Ginsenoside Rg3 promotes hepatic stellate cell ferroptosis by epigenetically regulating ACSL4 to suppress liver fibrosis progression.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Feb; 124(?):155289. doi:
10.1016/j.phymed.2023.155289. [PMID: 38176269] - Ning Jiang, Caihong Yao, Yiwen Zhang, Xinran Sun, M Iqbal Choudhary, Xinmin Liu. Ginsenoside Rg1 Attenuates Chronic Sleep Deprivation-Induced Hippocampal Mitochondrial Dysfunction and Improves Memory by the AMPK-SIRT3 Pathway.
Journal of agricultural and food chemistry.
2024 Jan; 72(4):2362-2373. doi:
10.1021/acs.jafc.3c04618. [PMID: 38236060] - Lan Yang, Jenny Jie Chen, Brian Sheng-Xian Teo, Jiong Zhang, Mingqiang Jiang. Research Progress on the Antitumor Molecular Mechanism of Ginsenoside Rh2.
The American journal of Chinese medicine.
2024 Jan; ?(?):1-14. doi:
10.1142/s0192415x24500095. [PMID: 38291582] - Jie Chen, Bin Zhang, Liwei Wu, Jiabin Xu. Ginsenoside Rg3 exhibits anti-catabolic and anti-apoptotic effects in IL-1β treated human disc nucleus pulposus cells and in a rat model of disc degeneration by inactivating the MAPK pathway.
Cellular and molecular biology (Noisy-le-Grand, France).
2024 Jan; 70(1):233-238. doi:
10.14715/cmb/2024.70.1.32. [PMID: 38372089] - Wenxiang Fan, Qi Liao, Linhong Fan, Qi Li, Longchan Liu, Ziying Wang, Yuqi Mei, Linnan Li, Li Yang, Zhengtao Wang. An innovative processing driven efficient transformation of rare ginsenosides enhances anti-platelet aggregation potency of notoginseng by integrated analyses of processing-(chemical) profiling-pharmacodynamics.
Journal of ethnopharmacology.
2024 Jan; 319(Pt 1):117126. doi:
10.1016/j.jep.2023.117126. [PMID: 37716488] - Jiali Fan, Feng Liu, Wenhua Ji, Xiao Wang, Lili Li. Comprehensive Investigation of Ginsenosides in the Steamed Panax quinquefolius with Different Processing Conditions Using LC-MS.
Molecules (Basel, Switzerland).
2024 Jan; 29(3):. doi:
10.3390/molecules29030623. [PMID: 38338369] - Ai Mi, Qinxue Hu, Ying Liu, Yanna Zhao, Fenglin Shen, Jinjian Lan, Keren Lv, Bolin Wang, Ruilan Gao, Xiaoling Yu. Hepatoprotective efficacy and interventional mechanism of the panaxadiol saponin component in high-fat diet-induced NAFLD mice.
Food & function.
2024 Jan; 15(2):794-808. doi:
10.1039/d3fo03572g. [PMID: 38131276] - Shunyao Qi, Tiexin Zeng, Le Sun, Meiling Yin, Peiling Wu, Pei Ma, Lijia Xu, Peigen Xiao. The effect of vine tea (Ampelopsis grossedentata) extract on fatigue alleviation via improving muscle mass.
Journal of ethnopharmacology.
2024 Jan; 325(?):117810. doi:
10.1016/j.jep.2024.117810. [PMID: 38266948] - Huimin Zhou, Yan Liu, Yong Su, Pengmin Ji, Liangliang Kong, Ran Sun, Duoduo Zhang, Hanyang Xu, Weiping Li, Weizu Li. Ginsenoside Rg1 attenuates lipopolysaccharide-induced chronic liver damage by activating Nrf2 signaling and inhibiting inflammasomes in hepatic cells.
Journal of ethnopharmacology.
2024 Jan; 324(?):117794. doi:
10.1016/j.jep.2024.117794. [PMID: 38244950] - Li-Juan Ma, Xiao Liu, Liwei Guo, Yuan Luo, Beibei Zhang, Xiaoxue Cui, Kuan Yang, Jing Cai, Fang Liu, Ni Ma, Feng-Qing Yang, Xiahong He, She-Po Shi, Jian-Bo Wan. Discovery of plant chemical defence mediated by a two-component system involving β-glucosidase in Panax species.
Nature communications.
2024 Jan; 15(1):602. doi:
10.1038/s41467-024-44854-7. [PMID: 38238334] - Chang Liu, Tingting Lv, Yanhua Shen, Tao Liu, Mingming Liu, Jian Hu, Sizhang Liu, Yang Jiang, Meiping Zhang, Mingzhu Zhao, Kangyu Wang, Yi Wang. Genome-wide identification and integrated analysis of TCP genes controlling ginsenoside biosynthesis in Panax ginseng.
BMC plant biology.
2024 Jan; 24(1):47. doi:
10.1186/s12870-024-04729-x. [PMID: 38216888] - Dongxu Li, Zhao-Bo Luo, Jun Zhu, Jun-Xia Wang, Zheng-Yun Jin, Shaobo Qi, Meiling Jin, Lin-Hu Quan. Ginsenoside F2-Mediated Intestinal Microbiota and Its Metabolite Propionic Acid Positively Impact the Gut-Skin Axis in Atopic Dermatitis Mice.
Journal of agricultural and food chemistry.
2024 Jan; 72(1):339-350. doi:
10.1021/acs.jafc.3c06015. [PMID: 38150707] - Junpeng Long, Yang Sun, Shasha Liu, Chen Chen, Qian Yan, Yuting Lin, Zhao Zhang, Shifeng Chu, Yantao Yang, Songwei Yang, Meiyu Lin, Xuan Liu, Jinping Liang, Naihong Chen, Qidi Ai. Ginsenoside Rg1 treats ischemic stroke by regulating CKLF1/CCR5 axis-induced neuronal cell pyroptosis.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Jan; 123(?):155238. doi:
10.1016/j.phymed.2023.155238. [PMID: 38128394] - Chao Hong, Anni Wang, Jiaxuan Xia, Jianming Liang, Ying Zhu, Dan Wang, Huaxing Zhan, Chunbo Feng, Xinnan Jiang, Junjie Pan, Jianxin Wang. Ginsenoside Rh2-Based Multifunctional Liposomes for Advanced Breast Cancer Therapy.
International journal of nanomedicine.
2024; 19(?):2879-2888. doi:
10.2147/ijn.s437733. [PMID: 38525007] - Honoka Ito, Michiho Ito. Genetic diversity of Panax ginseng cultivated in Japan and its relation with some plant characteristics.
Journal of natural medicines.
2024 Jan; 78(1):91-99. doi:
10.1007/s11418-023-01747-1. [PMID: 37707717] - Caidie Zhang, Yan Jin. Ginsenoside Rg5 induces NSCLC cell apoptosis and autophagy through PI3K/Akt/mTOR signaling pathway.
Human & experimental toxicology.
2024 Jan; 43(?):9603271241229140. doi:
10.1177/09603271241229140. [PMID: 38289222] - Chong-Zhi Wang, Chun-Feng Zhang, Qi-Hui Zhang, Chun-Su Yuan. Phytochemistry of Red Ginseng, a Steam-Processed Panax ginseng.
The American journal of Chinese medicine.
2024; 52(1):35-55. doi:
10.1142/s0192415x24500022. [PMID: 38353635] - Hyun Ho Shin, Junyoung Park, Yeo-Jin Kim, Donghyeon Kim, Eun-Jung Jin, Ji Hyun Ryu. Hydrophilic/Hydrophobic Janus Nanofibers Containing Compound K for Cartilage Regeneration.
International journal of nanomedicine.
2024; 19(?):1683-1697. doi:
10.2147/ijn.s435156. [PMID: 38445226] - Jia-Long Guo, Chang Liu, Yao Wang, Cheng-Fu Yuan, Ding Yuan, Yu-Min He. [Research progress on development and utilization of minor ginsenosides].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2024 Jan; 49(2):304-314. doi:
10.19540/j.cnki.cjcmm.20230824.201. [PMID: 38403306] - Chunmei Yang, Cheng Qian, Weiwei Zheng, Guanglu Dong, Shan Zhang, Feihui Wang, Zhonghong Wei, Yuhua Xu, Aiyun Wang, Yang Zhao, Yin Lu. Ginsenoside Rh2 enhances immune surveillance of natural killer (NK) cells via inhibition of ERp5 in breast cancer.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2024 Jan; 123(?):155180. doi:
10.1016/j.phymed.2023.155180. [PMID: 38043385] - Yuanping Wang, Jiading Zheng, Xieyang Xiao, Cailing Feng, Yinghong Li, Hui Su, Ding Yuan, Qinghai Wang, Peihong Huang, Lili Jin. Ginsenoside Rd Attenuates Myocardial Ischemia/Reperfusion Injury by Inhibiting Inflammation and Apoptosis through PI3K/Akt Signaling Pathway.
The American journal of Chinese medicine.
2024; 52(2):433-451. doi:
10.1142/s0192415x24500186. [PMID: 38577825] - Linxian Zhao, Tongbo Zhang, Kai Zhang. Pharmacological effects of ginseng and ginsenosides on intestinal inflammation and the immune system.
Frontiers in immunology.
2024; 15(?):1353614. doi:
10.3389/fimmu.2024.1353614. [PMID: 38698858] - Yadan Hu, Chao Xiang, Dong Zhang, Fang Zhou, Dede Zhang. Nephroprotective effect of Ginsenoside Rg1 in lipopolysaccharide-induced sepsis in mice through the SIRT1/NF-κB signaling.
Folia histochemica et cytobiologica.
2024; 62(1):13-24. doi:
10.5603/fhc.97140. [PMID: 38563049] - Tokuro Iwabuchi, Kazuki Ogura, Kenta Hagiwara, Shogo Ueno, Hiroaki Kitamura, Haruyo Yamanishi, Yuki Tsunekawa, Akinori Kiso. Ginsenosides in Panax ginseng Extract Promote Anagen Transition by Suppressing BMP4 Expression and Promote Human Hair Growth by Stimulating Follicle-Cell Proliferation.
Biological & pharmaceutical bulletin.
2024; 47(1):240-244. doi:
10.1248/bpb.b23-00276. [PMID: 38246611] - Hong Chen, Xiangzhu Li, Hang Chi, Zhuo Li, Cuizhu Wang, Qianyun Wang, Hao Feng, Pingya Li. A Qualitative Analysis of Cultured Adventitious Ginseng Root's Chemical Composition and Immunomodulatory Effects.
Molecules (Basel, Switzerland).
2023 Dec; 29(1):. doi:
10.3390/molecules29010111. [PMID: 38202694] - Chu-Jun Li, Rong-Rong Zhai, Xiao-Yu Zhu, Zi-Fan Guo, Hua Yang. Discovery of effective combination from Renshen-Fuzi herbal pair against heart failure by spectrum-effect relationship analysis and zebrafish models.
Journal of ethnopharmacology.
2023 Dec; 317(?):116832. doi:
10.1016/j.jep.2023.116832. [PMID: 37352946] - Silu Liu, Weijia Chen, Yan Zhao, Ying Zong, Jianming Li, Zhongmei He. Research Progress on Effects of Ginsenoside Rg2 and Rh1 on Nervous System and Related Mechanisms.
Molecules (Basel, Switzerland).
2023 Dec; 28(23):. doi:
10.3390/molecules28237935. [PMID: 38067664] - Xuerong Chen, Meiling Li, Jiabiao Huang, Qiquan Qiu, Yongjie Liang, Jiang Meng, Rachel Yoonjo Park, Paul C H Li, Yue Sun. Development of organic three-phase laminar flow microfluidic chip for extraction of ginsenosides from Panax ginseng.
Journal of pharmaceutical and biomedical analysis.
2023 Nov; 236(?):115724. doi:
10.1016/j.jpba.2023.115724. [PMID: 37729745] - Chenyang Zhang, Huifang Yu, Jingxue Ye, Hongna Tong, Min Wang, Guibo Sun. Ginsenoside Rg3 Protects against Diabetic Cardiomyopathy and Promotes Adiponectin Signaling via Activation of PPAR-γ.
International journal of molecular sciences.
2023 Nov; 24(23):. doi:
10.3390/ijms242316736. [PMID: 38069059] - Lizhen Lin, Yuqing Zhao, Peng Wang, Tao Li, Yuhang Liang, Yu Chen, Xianyi Meng, Yudong Zhang, Guangyue Su. Amino Acid Derivatives of Ginsenoside AD-2 Induce HepG2 Cell Apoptosis by Affecting the Cytoskeleton.
Molecules (Basel, Switzerland).
2023 Nov; 28(21):. doi:
10.3390/molecules28217400. [PMID: 37959819] - Li-Hua Chen, You-Bo Zhang, Xiu-Wei Yang, Jing Xu, Zhao-Jing Wang, Yi-Zheng Sun, Wei Xu, Ying-Ping Wang. Application of UPLC-Triple TOF-MS/MS metabolomics strategy to reveal the dynamic changes of triterpenoid saponins during the decocting process of Asian ginseng and American ginseng.
Food chemistry.
2023 Oct; 424(?):136425. doi:
10.1016/j.foodchem.2023.136425. [PMID: 37263091] - Milton Packer. Qiliqiangxin: A multifaceted holistic treatment for heart failure or a pharmacological probe for the identification of cardioprotective mechanisms?.
European journal of heart failure.
2023 Oct; ?(?):. doi:
10.1002/ejhf.3068. [PMID: 37877337] - Kailu Zhou, Yangyang Zhang, Yikai Zhou, Minghao Xu, Shanshan Yu. Production of Gypenoside XVII from Ginsenoside Rb1 by Enzymatic Transformation and Their Anti-Inflammatory Activity In Vitro and In Vivo.
Molecules (Basel, Switzerland).
2023 Oct; 28(19):. doi:
10.3390/molecules28197001. [PMID: 37836844] - Wenfeng Shen, Paul A Dalby, Zheng Guo, Weina Li, Chenhui Zhu, Daidi Fan. Residue Effect-Guided Design: Engineering of S. Solfataricus β-Glycosidase to Enhance Its Thermostability and Bioproduction of Ginsenoside Compound K.
Journal of agricultural and food chemistry.
2023 Oct; ?(?):. doi:
10.1021/acs.jafc.3c04575. [PMID: 37812684] - Shiying Luo, Xuexin Yang, Yi Zhang, Tingting Kuang, Ce Tang. Spatial metabolomics method to reveal differential metabolomes in microregions of Panax quinquefolius roots by using ultra-performance liquid chromatography quadrupole/time of flight-mass spectrometry and desorption electrospray ionization mass spectrometry imaging.
Food chemistry.
2023 Oct; 435(?):137504. doi:
10.1016/j.foodchem.2023.137504. [PMID: 37813026] - Hao Liu, Haiqiang Zhang, Jianing Nie, Yang Yu, Qiao Li, Chongning Lv, Jincai Lu. Systematic analysis of the material basis and mechanism of total saponins of mountain cultivated ginseng against doxorubicin-induced cardiotoxicity based on integrating network pharmacology and in vivo substance profiling.
Phytochemical analysis : PCA.
2023 Oct; 34(7):755-771. doi:
10.1002/pca.3194. [PMID: 36529443]
