Piflufolastat F-18 (BioDeep_00000837918)
代谢物信息卡片
Piflufolastat F-18
化学式: C18H23FN4O8 (442.14998499999996)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC(=NC=C1C(=O)NCCCCC(C(=O)O)NC(=O)NC(CCC(=O)O)C(=O)O)F
InChI: InChI=1S/C18H23FN4O8/c19-13-6-4-10(9-21-13)15(26)20-8-2-1-3-11(16(27)28)22-18(31)23-12(17(29)30)5-7-14(24)25/h4,6,9,11-12H,1-3,5,7-8H2,(H,20,26)(H,24,25)(H,27,28)(H,29,30)(H2,22,23,31)/t11-,12-/m0/s1/i19-1
描述信息
V - Various > V09 - Diagnostic radiopharmaceuticals > V09I - Tumour detection
C1446 - Radiopharmaceutical Compound > C2124 - Radioconjugate
同义名列表
1 个代谢物同义名
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Peter George Maliha, Julia Singerman, Gad Abikhzer, Stephan Probst. Physiologic prostate-specific membrane antigen-targeted 18F-DCFPyL uptake in the epididymis head newly appreciated on digital PET/CT.
Nuclear medicine communications.
2021 May; 42(5):490-494. doi:
10.1097/mnm.0000000000001363. [PMID: 33395193] - Sara Harsini, Heather Saprunoff, Tina Alden, Behnoud Mohammadi, Don Wilson, François Bénard. The Effects of Monosodium Glutamate on PSMA Radiotracer Uptake in Men with Recurrent Prostate Cancer: A Prospective, Randomized, Double-Blind, Placebo-Controlled Intraindividual Imaging Study.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2021 01; 62(1):81-87. doi:
10.2967/jnumed.120.246983. [PMID: 32385167] - Yachao Liu, Guanyun Wang, Hongkai Yu, Yue Wu, Mu Lin, Jiangping Gao, Baixuan Xu. Comparison of 18F-DCFPyL and 18F-FDG PET/computed tomography for the restaging of clear cell renal cell carcinoma: preliminary results of 15 patients.
Nuclear medicine communications.
2020 Dec; 41(12):1299-1305. doi:
10.1097/mnm.0000000000001285. [PMID: 32941403] - Claudia Ortega, Josh Schaefferkoetter, Patrick Veit-Haibach, Reut Anconina, Alejandro Berlin, Nathan Perlis, Ur Metser. 18F-DCFPyL PET/CT in Patients with Subclinical Recurrence of Prostate Cancer: Effect of Lesion Size, Smoothing Filter, and Partial-Volume Correction on PROMISE Criteria.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2020 11; 61(11):1615-1620. doi:
10.2967/jnumed.120.241737. [PMID: 32198311] - Katherine A Zukotynski, Hossein Jadvar, Kylea Potvin, Steve Y Cho, Chun Ki Kim, Eric Winquist. Prostate Cancer Lymphangitic Pulmonary Carcinomatosis: Appearance on 18F-FDG PET/CT and 18F-DCFPyL PET/CT.
Clinical nuclear medicine.
2020 Sep; 45(9):727-729. doi:
10.1097/rlu.0000000000003109. [PMID: 32520499] - Rudolf A Werner, Ralph A Bundschuh, Lena Bundschuh, Constantin Lapa, Yafu Yin, Mehrbod S Javadi, Andreas K Buck, Takahiro Higuchi, Kenneth J Pienta, Martin G Pomper, Martin A Lodge, Michael A Gorin, Steven P Rowe. Semiquantitative Parameters in PSMA-Targeted PET Imaging with [18F]DCFPyL: Impact of Tumor Burden on Normal Organ Uptake.
Molecular imaging and biology.
2020 02; 22(1):190-197. doi:
10.1007/s11307-019-01375-w. [PMID: 31140110] - Karine Sahakyan, Xin Li, Martin A Lodge, Rudolf A Werner, Ralph A Bundschuh, Lena Bundschuh, Harshad R Kulkarni, Christiane Schuchardt, Richard P Baum, Kenneth J Pienta, Martin G Pomper, Ashley E Ross, Michael A Gorin, Steven P Rowe. Semiquantitative Parameters in PSMA-Targeted PET Imaging with [18F]DCFPyL: Intrapatient and Interpatient Variability of Normal Organ Uptake.
Molecular imaging and biology.
2020 02; 22(1):181-189. doi:
10.1007/s11307-019-01376-9. [PMID: 31115751] - Steven P Rowe, Scott P Campbell, Margarita Mana-Ay, Zsolt Szabo, Mohamad E Allaf, Kenneth J Pienta, Martin G Pomper, Ashley E Ross, Michael A Gorin. Prospective Evaluation of PSMA-Targeted 18F-DCFPyL PET/CT in Men with Biochemical Failure After Radical Prostatectomy for Prostate Cancer.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2020 01; 61(1):58-61. doi:
10.2967/jnumed.119.226514. [PMID: 31201249] - Bernard H E Jansen, Maqsood Yaqub, Jens Voortman, Matthijs C F Cysouw, Albert D Windhorst, Robert C Schuit, Gerbrand M Kramer, Alfons J M van den Eertwegh, Lothar A Schwarte, N Harry Hendrikse, André N Vis, Reindert J A van Moorselaar, Otto S Hoekstra, Ronald Boellaard, Daniela E Oprea-Lager. Simplified Methods for Quantification of 18F-DCFPyL Uptake in Patients with Prostate Cancer.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2019 12; 60(12):1730-1735. doi:
10.2967/jnumed.119.227520. [PMID: 31000583] - Alexa R Meyer, Michael A Carducci, Samuel R Denmeade, Mark C Markowski, Martin G Pomper, Philip M Pierorazio, Mohamad E Allaf, Steven P Rowe, Michael A Gorin. Improved identification of patients with oligometastatic clear cell renal cell carcinoma with PSMA-targeted 18F-DCFPyL PET/CT.
Annals of nuclear medicine.
2019 Aug; 33(8):617-623. doi:
10.1007/s12149-019-01371-8. [PMID: 31147927] - Maurits Wondergem, Friso M van der Zant, Ladan Rafimanesh-Sadr, Remco J J Knol. Effect of forced diuresis during 18F-DCFPyL PET/CT in patients with prostate cancer: activity in ureters, kidneys and bladder and occurrence of halo artefacts around kidneys and bladder.
Nuclear medicine communications.
2019 Jun; 40(6):652-656. doi:
10.1097/mnm.0000000000001007. [PMID: 30855543] - Yafu Yin, Scott P Campbell, Mark C Markowski, Philip M Pierorazio, Martin G Pomper, Mohamad E Allaf, Steven P Rowe, Michael A Gorin. Inconsistent Detection of Sites of Metastatic Non-Clear Cell Renal Cell Carcinoma with PSMA-Targeted [18F]DCFPyL PET/CT.
Molecular imaging and biology.
2019 06; 21(3):567-573. doi:
10.1007/s11307-018-1271-2. [PMID: 30218388] - Jeremy Li, Richard Xu, Chun K Kim, François Bénard, Anil Kapoor, Glenn Bauman, Katherine A Zukotynski. 18F-DCFPyL PET/CT in Oncocytoma.
Clinical nuclear medicine.
2018 Dec; 43(12):921-924. doi:
10.1097/rlu.0000000000002301. [PMID: 30300203] - Rudolf A Werner, Sara Sheikhbahaei, Krystyna M Jones, Mehrbod S Javadi, Lilja B Solnes, Ashley E Ross, Mohamad E Allaf, Kenneth J Pienta, Constantin Lapa, Andreas K Buck, Takahiro Higuchi, Martin G Pomper, Michael A Gorin, Steven P Rowe. Patterns of uptake of prostate-specific membrane antigen (PSMA)-targeted 18F-DCFPyL in peripheral ganglia.
Annals of nuclear medicine.
2017 Nov; 31(9):696-702. doi:
10.1007/s12149-017-1201-4. [PMID: 28831739] - Xin Li, Steven P Rowe, Jeffrey P Leal, Michael A Gorin, Mohamad E Allaf, Ashley E Ross, Kenneth J Pienta, Martin A Lodge, Martin G Pomper. Semiquantitative Parameters in PSMA-Targeted PET Imaging with 18F-DCFPyL: Variability in Normal-Organ Uptake.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2017 06; 58(6):942-946. doi:
10.2967/jnumed.116.179739. [PMID: 27932557] - Michael A Gorin, Steven P Rowe, Jody E Hooper, Max Kates, Hans-Joerg Hammers, Zsolt Szabo, Martin G Pomper, Mohamad E Allaf. PSMA-Targeted 18F-DCFPyL PET/CT Imaging of Clear Cell Renal Cell Carcinoma: Results from a Rapid Autopsy.
European urology.
2017 01; 71(1):145-146. doi:
10.1016/j.eururo.2016.06.019. [PMID: 27363386] - Steven P Rowe, Michael A Gorin, Hans J Hammers, M Som Javadi, Hazem Hawasli, Zsolt Szabo, Steve Y Cho, Martin G Pomper, Mohamad E Allaf. Imaging of metastatic clear cell renal cell carcinoma with PSMA-targeted ¹⁸F-DCFPyL PET/CT.
Annals of nuclear medicine.
2015 Dec; 29(10):877-82. doi:
10.1007/s12149-015-1017-z. [PMID: 26286635] - Ana P Kiess, Il Minn, Ying Chen, Robert Hobbs, George Sgouros, Ronnie C Mease, Mrudula Pullambhatla, Colette J Shen, Catherine A Foss, Martin G Pomper. Auger Radiopharmaceutical Therapy Targeting Prostate-Specific Membrane Antigen.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2015 Sep; 56(9):1401-1407. doi:
10.2967/jnumed.115.155929. [PMID: 26182968] - Markus Dietlein, Carsten Kobe, Georg Kuhnert, Simone Stockter, Thomas Fischer, Klaus Schomäcker, Matthias Schmidt, Felix Dietlein, Boris D Zlatopolskiy, Philipp Krapf, Raphael Richarz, Stephan Neubauer, Alexander Drzezga, Bernd Neumaier. Comparison of [(18)F]DCFPyL and [ (68)Ga]Ga-PSMA-HBED-CC for PSMA-PET Imaging in Patients with Relapsed Prostate Cancer.
Molecular imaging and biology.
2015 Aug; 17(4):575-84. doi:
10.1007/s11307-015-0866-0. [PMID: 26013479]