Cenerimod (BioDeep_00000837773)
代谢物信息卡片
化学式: C25H31N3O5 (453.2263596)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC1=C(C(=CC(=C1)C2=NOC(=N2)C3=CC(=NC(=C3)OC)C4CCCC4)C)OCC(CO)O
InChI: InChI=1S/C25H31N3O5/c1-4-16-10-18(9-15(2)23(16)32-14-20(30)13-29)24-27-25(33-28-24)19-11-21(17-7-5-6-8-17)26-22(12-19)31-3/h9-12,17,20,29-30H,4-8,13-14H2,1-3H3/t20-/m0/s1
数据库引用编号
5 个数据库交叉引用编号
- KEGGdrug: D11283
- PubChem: 49871973
- DrugBank: DB12705
- ChEMBL: CHEMBL4297505
- CAS: 1262414-04-9
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Estelle Gerossier, Saba Nayar, Sylvie Froidevaux, Charlotte G Smith, Celine Runser, Valentina Iannizzotto, Enrico Vezzali, Gabin Pierlot, Ulrich Mentzel, Mark J Murphy, Marianne M Martinic, Francesca Barone. Cenerimod, a selective S1P1 receptor modulator, improves organ-specific disease outcomes in animal models of Sjögren's syndrome.
Arthritis research & therapy.
2021 11; 23(1):289. doi:
10.1186/s13075-021-02673-x. [PMID: 34839819] - Pierre-Eric Juif, Jasper Dingemanse, Peter Winkle, Mike Ufer. Pharmacokinetics and Pharmacodynamics of Cenerimod, A Selective S1P1 R Modulator, Are Not Affected by Ethnicity in Healthy Asian and White Subjects.
Clinical and translational science.
2021 01; 14(1):143-147. doi:
10.1111/cts.12873. [PMID: 32860737] - Daniel S Strasser, Sylvie Froidevaux, Virginie Sippel, Estelle Gerossier, Ursula Grieder, Gabin M Pierlot, Andrea Kieninger-Graefitsch, Enrico Vezzali, Anna K Stalder, Bérengère Renault, Jesper Ryge, Aaron Hart, Ulrich Mentzel, Peter M A Groenen, Marcel P Keller, Marten Trendelenburg, Marianne M Martinic, Mark J Murphy. Preclinical to clinical translation of cenerimod, a novel S1P1 receptor modulator, in systemic lupus erythematosus.
RMD open.
2020 09; 6(2):. doi:
10.1136/rmdopen-2020-001261. [PMID: 32917831] - Marie-Laure Boof, Jan Jaap van Lier, Stephen English, Hartmut Fischer, Mike Ufer, Jasper Dingemanse. Absorption, distribution, metabolism, and excretion of cenerimod, a selective S1P1 receptor modulator in healthy subjects.
Xenobiotica; the fate of foreign compounds in biological systems.
2020 Aug; 50(8):947-956. doi:
10.1080/00498254.2020.1736688. [PMID: 32105166] - Miyu Kano, Tadahiro Kobayashi, Mutsumi Date, Momoko Tennichi, Yasuhito Hamaguchi, Daniel S Strasser, Kazuhiko Takehara, Takashi Matsushita. Attenuation of murine sclerodermatous models by the selective S1P1 receptor modulator cenerimod.
Scientific reports.
2019 01; 9(1):658. doi:
10.1038/s41598-018-37074-9. [PMID: 30679645]