(3-Carboxy-2-(R)-hydroxy-propyl)-trimethyl-ammonium (BioDeep_00000837736)
代谢物信息卡片
化学式: C7H16NO3+ (162.113)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C[N+](C)(C)CC(CC(=O)O)O
InChI: InChI=1S/C7H15NO3/c1-8(2,3)5-6(9)4-7(10)11/h6,9H,4-5H2,1-3H3/p+1/t6-/m1/s1
描述信息
COVID info from COVID-19 Disease Map
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
同义名列表
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:39547
- PubChem: 10918
- DrugBank: DB02648
- ChEMBL: CHEMBL1229656
- CAS: 44984-08-9
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
1 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(1)
- @COVID-19 Disease
Map["name"]:
2-Methyl-3-acetoacetyl-CoA + Coenzyme A ⟶ Acetyl-CoA + Propanoyl-CoA
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Stephanie E Reuter, Allan M Evans. Carnitine and acylcarnitines: pharmacokinetic, pharmacological and clinical aspects.
Clinical pharmacokinetics.
2012 Sep; 51(9):553-72. doi:
10.1007/bf03261931
. [PMID: 22804748] - Mohamed M Sayed-Ahmed, Meshan Lafi Aldelemy, Mohamed M Hafez, Othman A Al-Shabanah. Inhibition of gene expression of organic cation/carnitine transporter and antioxidant enzymes in oxazaphosphorines-induced acute cardiomyopathic rat models.
Oxidative medicine and cellular longevity.
2012; 2012(?):452902. doi:
10.1155/2012/452902
. [PMID: 22701146] - F Rocher, C Caruba, F Broly, C Lebrun. [L-carnitine treatment and fish odor syndrome: an unwaited adverse effect].
Revue neurologique.
2011 Jun; 167(6-7):541-4. doi:
10.1016/j.neurol.2010.08.015
. [PMID: 21481905] - Sanaa Ahmed Ali, Lilla Faddah, Ateff Abdel-Baky, Asmaa Bayoumi. Protective effect of L-carnitine and coenzyme Q10 on CCl₄-induced liver injury in rats.
Scientia pharmaceutica.
2010 Oct; 78(4):881-96. doi:
10.3797/scipharm.1006-02
. [PMID: 21179323] - Joy Allee, Joseph D Tobias. Perioperative care of a child with non-ketotic hyperglycinemia.
Saudi journal of anaesthesia.
2010 Sep; 4(3):197-201. doi:
10.4103/1658-354x.71578
. [PMID: 21189859] - Judith L Flanagan, Peter A Simmons, Joseph Vehige, Mark Dp Willcox, Qian Garrett. Role of carnitine in disease.
Nutrition & metabolism.
2010 Apr; 7(?):30. doi:
10.1186/1743-7075-7-30
. [PMID: 20398344] - Miroslav Cuturic, Ruth K Abramson, Robert R Moran, James W Hardin. Clinical outcomes and low-dose levocarnitine supplementation in psychiatric inpatients with documented hypocarnitinemia: a retrospective chart review.
Journal of psychiatric practice.
2010 Jan; 16(1):5-14. doi:
10.1097/01.pra.0000367773.03636.d1
. [PMID: 20098226] - Ling-Feng Tang, Hui Jiang, Xue-Jun Shang, Lian-Ming Zhao, Quan Bai, Kai Hong, De-Feng Liu, Jian-Ming Liu, Ren-Pei Yuan, Qian Chen, Lu-Lin Ma. [Seminal plasma levocarnitine significantly correlated with semen quality].
Zhonghua nan ke xue = National journal of andrology.
2008 Aug; 14(8):704-8. doi:
NULL
. [PMID: 18817342] - Daniela Silva-Adaya, Verónica Pérez-De La Cruz, María Nieves Herrera-Mundo, Karina Mendoza-Macedo, Juana Villeda-Hernández, Zbigniew Binienda, Syed F Ali, Abel Santamaría. Excitotoxic damage, disrupted energy metabolism, and oxidative stress in the rat brain: antioxidant and neuroprotective effects of L-carnitine.
Journal of neurochemistry.
2008 May; 105(3):677-89. doi:
10.1111/j.1471-4159.2007.05174.x
. [PMID: 18194214] - Yoshikazu Yonei, Yoko Takahashi, Sawako Hibino, Miwako Watanabe, Toshito Yoshioka. Effects on the Human Body of a Dietary Supplement Containing L-Carnitine and Garcinia cambogia Extract: A Study using Double-blind Tests.
Journal of clinical biochemistry and nutrition.
2008 Mar; 42(2):89-103. doi:
10.3164/jcbn.2008014
. [PMID: 18385825] - Eric D Weinhandl, Madhumati Rao, David T Gilbertson, Allan J Collins, Brian J G Pereira. Protective effect of intravenous levocarnitine on subsequent-month hospitalization among prevalent hemodialysis patients, 1998 to 2003.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2007 Nov; 50(5):803-12. doi:
10.1053/j.ajkd.2007.07.017
. [PMID: 17954293] - Yun-Feng Lv, Xin Hu, Kai-Shun Bi. Determination of mildronate in human plasma and urine by liquid chromatography-tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2007 Jun; 852(1-2):35-9. doi:
10.1016/j.jchromb.2006.12.031
. [PMID: 17287154] - C Lebrun, H Alchaar, M Candito, V Bourg, M Chatel. Levocarnitine administration in multiple sclerosis patients with immunosuppressive therapy-induced fatigue.
Multiple sclerosis (Houndmills, Basingstoke, England).
2006 Jun; 12(3):321-4. doi:
10.1191/135248506ms1275oa
. [PMID: 16764345] - Brian D Schreiber. Debate forum: levocarnitine therapy is rational and justified in selected dialysis patients.
Blood purification.
2006; 24(1):128-39. doi:
10.1159/000089449
. [PMID: 16361853] - Brian Schreiber. Levocarnitine and dialysis: a review.
Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition.
2005 Apr; 20(2):218-43. doi:
10.1177/0115426505020002218
. [PMID: 16207659] - Roberto Ferrari, E Merli, G Cicchitelli, D Mele, A Fucili, C Ceconi. Therapeutic effects of L-carnitine and propionyl-L-carnitine on cardiovascular diseases: a review.
Annals of the New York Academy of Sciences.
2004 Nov; 1033(?):79-91. doi:
10.1196/annals.1320.007
. [PMID: 15591005] - Allan Evans. Dialysis-related carnitine disorder and levocarnitine pharmacology.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2003 Apr; 41(4 Suppl 4):S13-26. doi:
10.1016/s0272-6386(03)00113-6
. [PMID: 12751050] - Giovanni Pistone, Angela Marino, Carmelo Leotta, Simona Dell'Arte, Giovanna Finocchiaro, Mariano Malaguarnera. Levocarnitine administration in elderly subjects with rapid muscle fatigue: effect on body composition, lipid profile and fatigue.
Drugs & aging.
2003; 20(10):761-7. doi:
10.2165/00002512-200320100-00004
. [PMID: 12875611] - Sundaram Kumaran, Balasubramanium Deepak, Balasubramanium Naveen, Chinnakkannu Panneerselvam. Effects of levocarnitine on mitochondrial antioxidant systems and oxidative stress in aged rats.
Drugs in R&D.
2003; 4(3):141-7. doi:
10.2165/00126839-200304030-00001
. [PMID: 12757399] - F Graziano, R Bisonni, V Catalano, R Silva, S Rovidati, E Mencarini, B Ferraro, F Canestrari, A M Baldelli, A De Gaetano, P Giordani, E Testa, V Lai. Potential role of levocarnitine supplementation for the treatment of chemotherapy-induced fatigue in non-anaemic cancer patients.
British journal of cancer.
2002 Jun; 86(12):1854-7. doi:
10.1038/sj.bjc.6600413
. [PMID: 12085175]