Flortaucipir F-18 (BioDeep_00000837728)
代谢物信息卡片
化学式: C16H10FN3 (263.08587120000004)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC2=C(C=C1C3=CN=C(C=C3)F)NC4=C2C=NC=C4
InChI: InChI=1S/C16H10FN3/c17-16-4-2-11(8-19-16)10-1-3-12-13-9-18-6-5-14(13)20-15(12)7-10/h1-9,20H/i17-1
描述信息
V - Various > V09 - Diagnostic radiopharmaceuticals > V09A - Central nervous system
C1446 - Radiopharmaceutical Compound > C2124 - Radioconjugate
同义名列表
1 个代谢物同义名
数据库引用编号
5 个数据库交叉引用编号
- KEGGdrug: D11210
- PubChem: 70957463
- DrugBank: DB14914
- ChEMBL: CHEMBL3545253
- CAS: 1522051-90-6
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Antoine Leuzy, Ruben Smith, Nicholas C Cullen, Olof Strandberg, Jacob W Vogel, Alexa Pichet Binette, Edilio Borroni, Shorena Janelidze, Tomas Ohlsson, Jonas Jögi, Rik Ossenkoppele, Sebastian Palmqvist, Niklas Mattsson-Carlgren, Gregory Klein, Erik Stomrud, Oskar Hansson. Biomarker-Based Prediction of Longitudinal Tau Positron Emission Tomography in Alzheimer Disease.
JAMA neurology.
2022 02; 79(2):149-158. doi:
10.1001/jamaneurol.2021.4654
. [PMID: 34928318] - Yun Zhou, Shaney Flores, Syahir Mansor, Russ C Hornbeck, Zhude Tu, Joel S Perlmutter, Beau Ances, John C Morris, Robert J Gropler, Tammie L S Benzinger. Spatially constrained kinetic modeling with dual reference tissues improves 18F-flortaucipir PET in studies of Alzheimer disease.
European journal of nuclear medicine and molecular imaging.
2021 09; 48(10):3172-3186. doi:
10.1007/s00259-020-05134-w
. [PMID: 33599811] - Chunhong Gao, Wei Gong, Meiyan Yang, Xiaoyang Chu, Yuli Wang, Zhiping Li, Yang Yang, Chunsheng Gao. T807-modified human serum albumin biomimetic nanoparticles for targeted drug delivery across the blood-brain barrier.
Journal of drug targeting.
2020 12; 28(10):1085-1095. doi:
10.1080/1061186x.2020.1777420
. [PMID: 32614677] - Sandeep S V Golla, Tessa Timmers, Rik Ossenkoppele, Colin Groot, Sander Verfaillie, Philip Scheltens, Wiesje M van der Flier, Lothar Schwarte, Mark A Mintun, Michael Devous, Robert C Schuit, Albert D Windhorst, Adriaan A Lammertsma, Ronald Boellaard, Bart N M van Berckel, Maqsood Yaqub. Quantification of Tau Load Using [18F]AV1451 PET.
Molecular imaging and biology.
2017 12; 19(6):963-971. doi:
10.1007/s11307-017-1080-z
. [PMID: 28374171] - Anne-Sophie Salabert, Charlotte Fontan, Caroline Fonta, Mathieu Alonso, Najat Loukh, Marie Bernadette Delisle, Mathieu Tafani, Pierre Payoux. Radiosynthesis of [18F]AV1451 in pharmaceutical conditions and its biological characteristics.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.
2017 Oct; 128(?):101-107. doi:
10.1016/j.apradiso.2017.06.032
. [PMID: 28689157] - Olivier Barret, David Alagille, Sandra Sanabria, Robert A Comley, Robby M Weimer, Edilio Borroni, Mark Mintun, Nicholas Seneca, Caroline Papin, Thomas Morley, Ken Marek, John P Seibyl, Gilles D Tamagnan, Danna Jennings. Kinetic Modeling of the Tau PET Tracer 18F-AV-1451 in Human Healthy Volunteers and Alzheimer Disease Subjects.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2017 07; 58(7):1124-1131. doi:
10.2967/jnumed.116.182881
. [PMID: 27908967] - Dustin W Wooten, Nicolas J Guehl, Eline E Verwer, Timothy M Shoup, Daniel L Yokell, Nevena Zubcevik, Neil Vasdev, Ross D Zafonte, Keith A Johnson, Georges El Fakhri, Marc D Normandin. Pharmacokinetic Evaluation of the Tau PET Radiotracer 18F-T807 (18F-AV-1451) in Human Subjects.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2017 Mar; 58(3):484-491. doi:
10.2967/jnumed.115.170910
. [PMID: 27660144]