Triazavirin (BioDeep_00000837712)
代谢物信息卡片
化学式: C5H4N6O3S (228.00655940000001)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CSC1=NC2=NN=C(C(=O)N2N1)[N+](=O)[O-]
InChI: InChI=1S/C5H4N6O3S/c1-15-5-6-4-8-7-2(11(13)14)3(12)10(4)9-5/h1H3,(H,6,8,9)
描述信息
COVID info from DrugBank, clinicaltrial, clinicaltrials, clinical trial, clinical trials
C471 - Enzyme Inhibitor > C29575 - DNA Polymerase Inhibitor
C254 - Anti-Infective Agent > C281 - Antiviral Agent
Corona-virus
Coronavirus
SARS-CoV-2
COVID-19
SARS-CoV
COVID19
SARS2
SARS
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1 个代谢物同义名
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Sergey V Valiulin, Andrey A Onischuk, Sergey N Dubtsov, Anatoly M Baklanov, Sergey V An'kov, Maria E Plokhotnichenko, Tatyana G Tolstikova, Galina G Dultseva, Vladimir L Rusinov, Valery N Charushin, Vasily M Fomin. Aerosol Inhalation Delivery of Triazavirin in Mice: Outlooks for Advanced Therapy Against Novel Viral Infections.
Journal of pharmaceutical sciences.
2021 03; 110(3):1316-1322. doi:
10.1016/j.xphs.2020.11.016. [PMID: 33249050] - Ivan Malík Jozef Čižmárik Gustáv Kováč Mária Pecháčová Lucia Hudecová. Triazavirin might be the new hope to fight Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).
Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti.
2021; 70(1):18-25. doi:
NULL. [PMID: 34237949] - Siyamak Shahab, Masoome Sheikhi. Triazavirin - Potential Inhibitor for 2019-nCoV Coronavirus M Protease: A DFT Study.
Current molecular medicine.
2021; 21(8):645-654. doi:
10.2174/1566524020666200521075848. [PMID: 32436829] - Ksenia V Kozhikhova, Maria N Ivantsova, Maria I Tokareva, Iliya D Shulepov, Andrey V Tretiyakov, Lev V Shaidarov, Vladimir L Rusinov, Maxim A Mironov. Preparation of chitosan-coated liposomes as a novel carrier system for the antiviral drug Triazavirin.
Pharmaceutical development and technology.
2018 Apr; 23(4):334-342. doi:
10.1080/10837450.2016.1242624. [PMID: 27681534] - S Ia Loginova, S V Borisevich, V L Rusinov, U N Ulomskiĭ, V N Charushin, O N Chupakhin. [Investigation of Triazavirin antiviral activity against tick-borne encephalitis pathogen in cell culture].
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic].
2014; 59(1-2):3-5. doi:
NULL. [PMID: 25051708] - S Ia Loginova, S V Borisevich, V L Rusinov, U N Ulomskiĭ, V N Charushin, O N Chupakhin. [Toxicity of triazavirin, a novel Russian antiinfluenza chemotherapeutic].
Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic].
2012; 57(11-12):8-10. doi:
NULL. [PMID: 23700930] - Inna Karpenko, Sergey Deev, Oleg Kiselev, Valerey Charushin, Vladimir Rusinov, Eugeney Ulomsky, Ella Deeva, Dmitry Yanvarev, Alexander Ivanov, Olga Smirnova, Sergey Kochetkov, Oleg Chupakhin, Marina Kukhanova. Antiviral properties, metabolism, and pharmacokinetics of a novel azolo-1,2,4-triazine-derived inhibitor of influenza A and B virus replication.
Antimicrobial agents and chemotherapy.
2010 May; 54(5):2017-22. doi:
10.1128/aac.01186-09. [PMID: 20194696]