Technetium Tc 99m oxidronate (BioDeep_00000837650)
代谢物信息卡片
Technetium Tc 99m oxidronate
化学式: CH6O7P2Tc (289.95887860000005)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(O)(P(=O)(O)O)P(=O)(O)O.[Tc]
InChI: /i
描述信息
D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents > D019275 - Radiopharmaceuticals
D050071 - Bone Density Conservation Agents > D004164 - Diphosphonates
C1446 - Radiopharmaceutical Compound > C2124 - Radioconjugate
同义名列表
1 个代谢物同义名
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
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PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Julien Dang, Mukedaisi Abulizi, Anissa Moktefi, Khalil El Karoui, Jean-François Deux, Diane Bodez, Fabien Le Bras, Karim Belhadj, Philippe Remy, Pauline Issaurat, Violaine Plante-Bordeneuve, Valérie Molinier-Frenkel, Pascale Fanen, Soulef Guendouz, Mounira Kharoubi, Emmanuel Itti, Thibaud Damy, Vincent Audard. Renal Infarction and Its Consequences for Renal Function in Patients With Cardiac Amyloidosis.
Mayo Clinic proceedings.
2019 06; 94(6):961-975. doi:
10.1016/j.mayocp.2019.02.012. [PMID: 31103217] - Lotte Hahn Enevoldsen, James Heaf, Liselotte Højgaard, Bo Zerahn, Philip Hasbak. Increased technetium-99 m hydroxy diphosphonate soft tissue uptake on bone scintigraphy in chronic kidney disease patients with secondary hyperparathyroidism: correlation with hyperphosphataemia.
Clinical physiology and functional imaging.
2017 Mar; 37(2):131-136. doi:
10.1111/cpf.12276. [PMID: 26148143] - Elisa Borsò, Giuseppe Boni, Sara Mazzarri, Ardico Cocciaro, Carlo Gambacciani, Antonio C Traino, Giampiero Manca, Mariano Grosso, Cristian Scatena, Valerio Ortenzi, Riccardo Vannozzi, Maria Cristina Marzola, Domenico Rubello, Giuliano Mariani. Disseminated bone metastases from occult thyroid cancer effectively treated with debulking surgery and a single dosimetry-guided administration of radioiodine.
Revista espanola de medicina nuclear e imagen molecular.
2015 Mar; 34(2):111-5. doi:
10.1016/j.remn.2014.09.004. [PMID: 25455505] - Seiichiro Ota, Masaki Uno, Masaki Kato, Masanobu Ishiguro, Takahiro Natsume, Kaoru Kikukawa, Masanori Tadokoro, Takashi Ichihara, Hiroshi Toyama. (89)Sr bremsstrahlung single photon emission computed tomography using a gamma camera for bone metastases.
Annals of nuclear medicine.
2014 Feb; 28(2):112-9. doi:
10.1007/s12149-013-0788-3. [PMID: 24297387] - Sung Hoon Kim, Seok Kil Zeon, Byung Wook Choi, Il Jo, Hae Won Kim, Kyoung Sook Won, Su Jin Kim. Extraosseous bone tracer accumulation of the liver on 99mTc-HDP bone scintigraphy in intermittent bleeding after iatrogenic liver injury.
Clinical nuclear medicine.
2012 Oct; 37(10):995-6. doi:
10.1097/rlu.0b013e318251e21f. [PMID: 22899196] - J H Chuah, C F Loughran. Increased renal uptake of technetium-99m HEDP in a patient with breast cancer.
The British journal of radiology.
2010 Jan; 83(985):82-4. doi:
10.1259/bjr/48571524. [PMID: 20139250] - Hans Jacobsson. Short-time ingestion of colas influences the activity distribution at bone scintigraphy: experimental studies in the mouse.
Journal of the American College of Nutrition.
2008 Apr; 27(2):332-6. doi:
10.1080/07315724.2008.10719708. [PMID: 18689567] - Sameer Khan, Zarni Win, Claire R Lloyd, Deena Neriman, Teresa A Szyszko, William E Svensson, Adil Al-Nahhas. Acrometastasis to the foot: an unusual presentation of transitional cell carcinoma of the bladder.
Nuclear medicine review. Central & Eastern Europe.
2007; 10(1):26-8. doi:
NULL. [PMID: 17694499] - Hiroki Sasaki, Kazunari Ishii, Atsushi K Kono, Naokazu Miyamoto, Tetsuya Fukuda, Junko Kanata, Yasushi Kita. Early disappearance of calcification in posterior paraspinal muscles in a patient with rhabdomyolysis associated with neuroleptic malignant syndrome.
Radiation medicine.
2006 Jul; 24(6):463-6. doi:
10.1007/s11604-006-0047-9. [PMID: 16958430] - Hayato Kaida, Masatoshi Ishibashi, Hidemi Nishida, Kenkichi Baba, Naofumi Hayabuchi. Rhabdomyolysis induced by psychotropic drugs.
Clinical nuclear medicine.
2005 Aug; 30(8):569-70. doi:
10.1097/01.rlu.0000170057.35145.f4. [PMID: 16024959] - Hayato Kaida, Masatoshi Ishibashi, Hidemi Nishida, Kenkichi Baba, Yuji Hiromatsu, Seiya Okuda, Naofumi Hayabuchi. Usefulness of whole PTH assay in patients with renal osteodystrophy--correlation with bone scintigraphy.
Annals of nuclear medicine.
2005 May; 19(3):179-84. doi:
10.1007/bf02984602. [PMID: 15981669] - Hidemi Nishida, Hayato Kaida, Masatoshi Ishibashi, Yuji Hiromatsu, Kenkichi Baba, Shuji Iida, Seiya Okuda. Usefulness of bone uptake ratio of bone scintigraphy in hemodialysis patients.
Annals of nuclear medicine.
2005 Apr; 19(2):91-4. doi:
10.1007/bf03027386. [PMID: 15909487] - Koichiro Abe, Masayuki Sasaki, Yasuo Kuwabara, Hirofumi Koga, Shingo Baba, Koichiro Kaneko, Kazutaka Hayashi, Yoshiyuki Shioyama, Tatsuro Tajiri, Sachiyo Suita, Hiroshi Honda. Extraosseous accumulation of (99m)Tc-HMDP to radiation nephropathy, mimicking recurrent neuroblastoma.
Annals of nuclear medicine.
2005 Feb; 19(1):35-40. doi:
10.1007/bf02986333. [PMID: 15770971] - Jeffrey M Gremmels, Gerald A Kirk. Two patients with abnormal skeletal muscle uptake of Tc-99m hydroxymethylene diphosphonate following liver transplant: nephrogenic fibrosing dermopathy and graft vs host disease.
Clinical nuclear medicine.
2004 Nov; 29(11):694-7. doi:
10.1097/00003072-200411000-00004. [PMID: 15483480] - Seiji Kurata, Masatoshi Ishibashi, Hidemi Nishida, Yuji Hiromatsu, Naofumi Hayabuchi. A clinical assessment of the relationship between bone scintigraphy and serum biochemical markers in hemodialysis patients.
Annals of nuclear medicine.
2004 Sep; 18(6):513-8. doi:
10.1007/bf02984569. [PMID: 15515752] - Mehmet Onur Demirkol, Hülya Seymen, Alev Kadoğlu. Visceral calcification diagnosed by bone scintigraphy.
Clinical nuclear medicine.
2004 May; 29(5):332-4. doi:
10.1097/01.rlu.0000123326.07954.2a. [PMID: 15069340] - Maria del Sol Pérez-Lago, M C De Vírgala, R Siurana, M J Ferrando, M Danús, V Izquierdo, A Pujol. Altered biodistribution of bone seeking agents in the presence of iron-overload.
Clinical nuclear medicine.
2004 Mar; 29(3):214-6. doi:
10.1097/01.rlu.0000114019.52713.e3. [PMID: 15162998] - G M Blake, A E B Moore, S J Park-Holohan, I Fogelman. A direct in vivo measurement of 99mTc-methylene diphosphonate protein binding.
Nuclear medicine communications.
2003 Jul; 24(7):829-35. doi:
10.1097/00006231-200307000-00014. [PMID: 12813203] - Winfried Brenner, Willm Uwe Kampen, Corinna Brümmer, Corinna von Forstner, Maaz Zuhayra, Norbert Czech, Claus Muhle, Eberhard Henze. Bone uptake studies in rabbits before and after high-dose treatment with 153Sm-EDTMP or 186Re-HEDP.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2003 Feb; 44(2):247-51. doi:
NULL. [PMID: 12571217] - V M Poblete García, S Rodado Marina, A García Vicente, A Soriano Castrejón. [Benign myocardial uptake of 99mTc-HMDP in prostate carcinoma: based on three cases].
Revista espanola de medicina nuclear.
2003 Jan; 22(1):35-9. doi:
10.1016/s0212-6982(03)72139-9. [PMID: 12550032] - F Jamar, F A Houssiau, J-P Devogelaer, P T Chapman, D O Haskard, V Beaujean, C Beckers, D-H Manicourt, A M Peters. Scintigraphy using a technetium 99m-labelled anti-E-selectin Fab fragment in rheumatoid arthritis.
Rheumatology (Oxford, England).
2002 Jan; 41(1):53-61. doi:
10.1093/rheumatology/41.1.53. [PMID: 11792880] - T Kubota, Y Ushijima, C Okuyama, T Kubo, T Nishimura. Tracer accumulation in femoral head during early phase of bone scintigraphy after renal transplantation.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2001 Dec; 42(12):1789-94. doi:
NULL. [PMID: 11752074] - K Sueyoshi, I Narabayashi, T Aratani, K Doi, T Komori, Y Ogura, K Utsunomiya, T Shimidzu. Utility of Tc-99m GSA whole-body scintigraphy in detecting bone metastases from hepatocellular carcinoma.
Clinical nuclear medicine.
2001 Mar; 26(3):221-4. doi:
10.1097/00003072-200103000-00008. [PMID: 11245114] - H Ohta. Liver uptake and increased renal uptake of Tc-99m HMDP in a patient with iron overload.
Clinical nuclear medicine.
2001 Feb; 26(2):164-5. doi:
10.1097/00003072-200102000-00024. [PMID: 11201486] - J Frendin, B Funkquist, K Hansson, M Lönnemark, J Carlsten. Diagnostic imaging of foreign body reactions in dogs with diffuse back pain.
The Journal of small animal practice.
1999 Jun; 40(6):278-85. doi:
10.1111/j.1748-5827.1999.tb03080.x. [PMID: 10404489] - F Pons, L Alvarez, P Peris, N Guañabens, S Vidal-Sicart, A Monegal, J Pavía, A M Ballesta, J Muños-Gómez, R Herranz. Quantitative evaluation of bone scintigraphy in the assessment of Paget's disease activity.
Nuclear medicine communications.
1999 Jun; 20(6):525-8. doi:
10.1097/00006231-199906000-00006. [PMID: 10451864] - W J Shih, J K Han, S Brandenburge, S Magoun, L Mostowycz. Localization of a bone imaging agent in a calcified hematoma.
Journal of nuclear medicine technology.
1999 Mar; 27(1):45-7. doi:
NULL. [PMID: 10322576] - M Sarwar, T Higuchi, K Tomiyoshi, T Inoue, N Oriuchi, A Kbalil, S Alyafei, H Sakahara, J K Chung, K Endo. 99mTc-labeled chimeric anti-NCA 95 antigranulocyte monoclonal antibody for bone marrow imaging.
Radiation medicine.
1998 Sep; 16(5):391-7. doi:
NULL. [PMID: 9862166] - L G Flores, S Nagamachi, S Jinnouchi, T Ohnishi, S Futami, H Nakahara, S Tamura. Relationship between extraosseous accumulation in bone scintigraphy with 99Tcm-HMDP and histopathology.
Nuclear medicine communications.
1998 Apr; 19(4):347-54. doi:
10.1097/00006231-199804000-00009. [PMID: 9853325] - T Higuchi, T Hirano, T Inoue, J Aoki, K Ueki, R Wakamatsu, S Yano, T Naruse, K Endo. Pentavalent technetium-99m-dimercaptosuccinic acid scintigraphy in renal osteodystrophy.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
1998 Mar; 39(3):541-3. doi:
NULL. [PMID: 9529307] - B Agren, U Rudberg, K Måre, P Aspelin. Bone marrow imaging of bone marrow transplanted multiple myeloma patients.
Clinical nuclear medicine.
1997 Feb; 22(2):80-92. doi:
10.1097/00003072-199702000-00003. [PMID: 9031764] - M A MacLeod, A S Houston. Functional bone imaging in the detection of ischemic osteopathies.
Clinical nuclear medicine.
1997 Jan; 22(1):1-5. doi:
10.1097/00003072-199701000-00001. [PMID: 8993864] - A S Lam, M R Puncher, P J Blower. In vitro and in vivo studies with pentavalent technetium-99m dimercaptosuccinic acid.
European journal of nuclear medicine.
1996 Dec; 23(12):1575-82. doi:
10.1007/bf01249619. [PMID: 8929310] - S Kinuya, J Taki, M Fujioka, T Michigishi, N Tonami. Metastatic calcification: accumulation of a bone tracer during dynamic data acquisition.
Annals of nuclear medicine.
1996 Nov; 10(4):433-5. doi:
10.1007/bf03164806. [PMID: 9006730] - T Ota, I Yamamoto, H Ohnishi, I Yuh, Y Kigami, T Suzuki, Y Yamamura, K Murata, R Morita. Three-dimensional bone scintigraphy using volume-rendering technique and SPECT.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
1996 Sep; 37(9):1567-70. doi:
NULL. [PMID: 8790220] - Y Kigami, I Yamamoto, H Ohnishi, H Miura, Y Ohnaka, T Ota, I Yuu, K Masuda, R Morita. Age-related change of technetium-99m-HMDP distribution in the skeleton.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
1996 May; 37(5):815-8. doi:
NULL. [PMID: 8965151] - B Chandramouly, R Sacchi, V Bhide. Extensive nonosseous Tc-99m HDP accumulation in B-cell malignant lymphoma. Correlation with Ga-67 scintigraphy.
Clinical nuclear medicine.
1996 May; 21(5):424-5. doi:
10.1097/00003072-199605000-00027. [PMID: 8732853] - G Galli, A Bagnato, M Galli. A simple method for estimating the skeletal uptake of diphosphonates.
Nuclear medicine communications.
1995 Sep; 16(9):773-8. doi:
10.1097/00006231-199509000-00008. [PMID: 7478410] - T Hirano, H Otake, K Ichikawa, Y Ohmori, K Kunitomo. Metastatic calcification. Difference of uptake between Tc-99m HMDP and Ga-67 citrate.
Clinical nuclear medicine.
1995 Sep; 20(9):849-50. doi:
10.1097/00003072-199509000-00026. [PMID: 8521674] - I Ricordel, E Bussy. [Necessity of radiopharmaceutical control and vigilance].
Annales pharmaceutiques francaises.
1995; 53(1):8-12. doi:
NULL. [PMID: 7741426] - S Weismüller, R P Baum, A Zöller, G Hör. [Intestinal accumulation of 99mTc-HMDP: an unusual finding in bone scintigraphy].
Nuklearmedizin. Nuclear medicine.
1994 Apr; 33(2):142-4. doi:
NULL. [PMID: 8177758] - F Tenenbaum, M Schlumberger, F Bonnin, J Lumbroso, B Aubert, H Benali, C Parmentier. Usefulness of technetium-99m hydroxymethylene diphosphonate scans in localizing bone metastases of differentiated thyroid carcinoma.
European journal of nuclear medicine.
1993 Dec; 20(12):1168-74. doi:
10.1007/bf00171015. [PMID: 8299652] - M J Fordyce, L Solomon. Early detection of avascular necrosis of the femoral head by MRI.
The Journal of bone and joint surgery. British volume.
1993 May; 75(3):365-7. doi:
10.1302/0301-620x.75b3.8496201. [PMID: 8496201] - T Mochizuki, H Kawai, T Nishimura, M Kaneko, Y Takehara, K Ichijo, M Nakamura. Uriposia after intravenous administration of technetium-99m HMDP.
Clinical nuclear medicine.
1993 May; 18(5):435-6. doi:
10.1097/00003072-199305000-00014. [PMID: 8508582] - K Binnur, G Firat, T Sukran, E Metin. Tc-99m HMDP uptake by the kidney in sickle cell disease.
Clinical nuclear medicine.
1992 Mar; 17(3):236. doi:
10.1097/00003072-199203000-00018. [PMID: 1611798] - M D Stone, D H Marshall, D J Hosking, A C Perkins, A J Evans, M L Wastie. Bisphosphonate space measurement in Paget's disease of bone treated with APD.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
1992 Mar; 7(3):295-301. doi:
10.1002/jbmr.5650070308. [PMID: 1316715] - U Karayalcin, B Karayalcin, G Yakupoglu, A Yildiz, M Erkilic. Tc-99m-HMDP bone uptake quantification and plasma osteocalcin levels in hemodialysis patients--a preliminary study.
Annals of nuclear medicine.
1992 Feb; 6(1):9-12. doi:
10.1007/bf03164636. [PMID: 1520575] - W J Shih, J Collins, B Wierzbinski, S Magoun, U Y Ryo. Tc-99m HMDP bone scintigraphic findings in association with concurrent serum osteocalcin measurements.
Radiation medicine.
1991 Jul; 9(4):162-6. doi:
NULL. [PMID: 1961943] - A Evans, A Perkins, M Wastie, M Stone, D Hosking. The diphosphonate space: a useful quantitative index of disease activity in patients undergoing hydroxy methylene diphosphonate (HMDP) bone imaging for Paget's disease [corrected].
European journal of nuclear medicine.
1991; 18(9):757-9. doi:
10.1007/bf00956717. [PMID: 1809266] - F A de Jonge, E K Pauwels, N A Hamdy. Scintigraphy in the clinical evaluation of disorders of mineral and skeletal metabolism in renal failure.
European journal of nuclear medicine.
1991; 18(10):839-55. doi:
10.1007/bf00175066. [PMID: 1743208] - M S Bernard, M Hayward, C Hayward, L Mundy. Evaluation of intense renal parenchymal activity ('hot kidneys') on bone scintigraphy.
Clinical nuclear medicine.
1990 Apr; 15(4):254-6. doi:
10.1097/00003072-199004000-00010. [PMID: 2340659] - K Torizumi, H Aibata, S Kiji, A Ueyoshi, Y Kiura, Y Okamoto, T Tuda, K Ota. [Accumulation velocity of 99mTc-HMDP in hip joint diseases].
Radioisotopes.
1988 Jul; 37(7):398-401. doi:
10.3769/radioisotopes.37.7_398. [PMID: 3262888] - W J Shih, C Riley, S Magoun, U Y Ryo. Intense bone imaging agent uptake in the soft tissues of the lower legs and feet relating to ischemia and cold exposure.
European journal of nuclear medicine.
1988; 14(7-8):419-21. doi:
10.1007/bf00254397. [PMID: 3181193] - L Mosekilde, C Hasling, P C Tågehøj Jensen, F Tågehøj Jensen. Bisphosphonate whole body retention test: relations to bone mineralization rate, renal function and bone mineral content in osteoporosis and metabolic bone disorders.
European journal of clinical investigation.
1987 Dec; 17(6):530-7. doi:
10.1111/j.1365-2362.1987.tb01153.x. [PMID: 3123252] - W J Shih, F H DeLand, P A Domstad, M Purcell. Ring-like uptake pattern of a skeletal imaging agent in a huge renal cell carcinoma.
Clinical nuclear medicine.
1986 May; 11(5):319-21. doi:
10.1097/00003072-198605000-00005. [PMID: 3698427] - W J Shih, P A Domstad, A Lieber, F H DeLand, J J Coupal. Localization of 99mTc-HMDP in hepatic metastases from colonic carcinoma.
AJR. American journal of roentgenology.
1986 Feb; 146(2):333-6. doi:
10.2214/ajr.146.2.333. [PMID: 3484584] - A Taylor, R Bedont, R Raabe. Prolonged half-life following diuretic radionuclide urography as evidence of ureteral obstruction.
Clinical nuclear medicine.
1985 Nov; 10(11):796-8. doi:
10.1097/00003072-198511000-00010. [PMID: 4075673] - H M Dey, M K Karimeddini, R P Spencer, J J Sziklas. Evaluation of renal-skeleton ratio of technetium-99m phosphonate in multiple myeloma.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
1985 Nov; 26(11):1270-4. doi:
NULL. [PMID: 4056922] - J A Orzel, T G Rudd. Heterotopic bone formation: clinical, laboratory, and imaging correlation.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
1985 Feb; 26(2):125-32. doi:
NULL. [PMID: 3918147] - H L Atkins, Z H Oster. Myocardial uptake of a bone tracer associated with hypercalcemia.
Clinical nuclear medicine.
1984 Nov; 9(11):613-5. doi:
10.1097/00003072-198411000-00001. [PMID: 6509834] - Z Salimi, W Vas, P Tang-Barton, P Suresh, B Carlin. Increased renal parenchymal accumulation of Tc-99m HDP in kidney contusion.
Clinical nuclear medicine.
1984 Oct; 9(10):574-6. doi:
10.1097/00003072-198410000-00008. [PMID: 6488654] - N Tonami, K Koizumi, K Hisada. [Clinical study of diffusely increased 99mTc phosphonate compounds uptake in both kidneys].
Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica.
1982 Jun; 42(6):576-81. doi:
NULL. [PMID: 7145618]