Fluciclovine (18F) (BioDeep_00000837603)
代谢物信息卡片
化学式: C5H8FNO2 (133.053904)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C(CC1(C(=O)O)N)F
InChI: InChI=1S/C5H8FNO2/c6-3-1-5(7,2-3)4(8)9/h3H,1-2,7H2,(H,8,9)/i6-1
描述信息
V - Various > V09 - Diagnostic radiopharmaceuticals > V09I - Tumour detection
C1446 - Radiopharmaceutical Compound > C2124 - Radioconjugate
同义名列表
1 个代谢物同义名
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:134703
- KEGGdrug: D10860
- PubChem: 450601
- DrugBank: DB13146
- ChEMBL: CHEMBL447701
- ChEMBL: CHEMBL254468
- CAS: 222727-39-1
- MetaboLights: MTBLC134703
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Chenxi Wu, Charles Marcus, Yoram Baum, Omer Kucuk, David M Schuster. Treatment Response to Lycopene in Recurrent Prostate Cancer Confirmed on 18F-Fluciclovine PET/CT.
Clinical nuclear medicine.
2023 Jan; ?(?):. doi:
10.1097/rlu.0000000000004547
. [PMID: 36728146] - Bital Savir-Baruch, Peter L Choyke, Steven P Rowe, David M Schuster, Rathan M Subramaniam, Hossein Jadvar. Role of 18F-Fluciclovine and Prostate-Specific Membrane Antigen PET/CT in Guiding Management of Oligometastatic Prostate Cancer: AJR Expert Panel Narrative Review.
AJR. American journal of roentgenology.
2021 04; 216(4):851-859. doi:
10.2214/ajr.20.24711
. [PMID: 33206564] - Ali Baiomy, Lucia Martiniova, Eleni Efstathiou, David M Schuster, Gregory Ravizzini. Prostate Cancer Liver Metastases Presenting as Relatively Photopenic Lesions on 18F-Fluciclovine PET/CT.
Clinical nuclear medicine.
2021 Apr; 46(4):e240-e241. doi:
10.1097/rlu.0000000000003377
. [PMID: 33208612] - Kesav Raghavan, Robert R Flavell, Antonio C Westphalen, Spencer C Behr. Gastrointestinal Stromal Tumor Incidentally Detected on 18F-Fluciclovine PET/CT.
Clinical nuclear medicine.
2021 Apr; 46(4):345-347. doi:
10.1097/rlu.0000000000003426
. [PMID: 33234933] - Petra Lovrec, David M Schuster, Robert H Wagner, Medhat Gabriel, Bital Savir-Baruch. Characterizing and Mitigating Bladder Radioactivity on 18F-Fluciclovine PET/CT.
Journal of nuclear medicine technology.
2020 Mar; 48(1):24-29. doi:
10.2967/jnmt.119.230581
. [PMID: 31604898] - Joseph R England, Jeremy Paluch, Leslie K Ballas, Hossein Jadvar. 18F-Fluciclovine PET/CT Detection of Recurrent Prostate Carcinoma in Patients With Serum PSA ≤ 1 ng/mL After Definitive Primary Treatment.
Clinical nuclear medicine.
2019 Mar; 44(3):e128-e132. doi:
10.1097/rlu.0000000000002432
. [PMID: 30589673] - Bital Savir-Baruch, Lucia Zanoni, David M Schuster. Imaging of Prostate Cancer Using Fluciclovine.
The Urologic clinics of North America.
2018 Aug; 45(3):489-502. doi:
10.1016/j.ucl.2018.03.015
. [PMID: 30031468] - Masahiro Ono, Atsumi Baden, Hiroyuki Okudaira, Masato Kobayashi, Keiichi Kawai, Shuntaro Oka, Hirokatsu Yoshimura. Assessment of Amino Acid/Drug Transporters for Renal Transport of [18F]Fluciclovine (anti-[18F]FACBC) in Vitro.
International journal of molecular sciences.
2016 Oct; 17(10):. doi:
10.3390/ijms17101730
. [PMID: 27754421] - Masaru Kanagawa, Yoshihiro Doi, Shuntaro Oka, Ryohei Kobayashi, Norihito Nakata, Masahito Toyama, Yoshifumi Shirakami. Comparison of trans-1-amino-3-[18F]fluorocyclobutanecarboxylic acid (anti-[18F]FACBC) accumulation in lymph node prostate cancer metastasis and lymphadenitis in rats.
Nuclear medicine and biology.
2014 Aug; 41(7):545-51. doi:
10.1016/j.nucmedbio.2014.04.004
. [PMID: 24816330] - Brian J McParland, Anders Wall, Silvia Johansson, Jens Sørensen. The clinical safety, biodistribution and internal radiation dosimetry of [¹⁸F]fluciclovine in healthy adult volunteers.
European journal of nuclear medicine and molecular imaging.
2013 Aug; 40(8):1256-64. doi:
10.1007/s00259-013-2403-1
. [PMID: 23613104] - Jens Sörensen, Rikard Owenius, Michelle Lax, Silvia Johansson. Regional distribution and kinetics of [18F]fluciclovine (anti-[18F]FACBC), a tracer of amino acid transport, in subjects with primary prostate cancer.
European journal of nuclear medicine and molecular imaging.
2013 Feb; 40(3):394-402. doi:
10.1007/s00259-012-2291-9
. [PMID: 23208700] - Yuji Asano, Yusuke Inoue, Yasuhiko Ikeda, Kei Kikuchi, Toshimasa Hara, Chikako Taguchi, Takanori Tokushige, Hideki Maruo, Tohoru Takeda, Tomomi Nakamura, Tomoe Fujita, Yuji Kumagai, Kazushige Hayakawa. Phase I clinical study of NMK36: a new PET tracer with the synthetic amino acid analogue anti-[18F]FACBC.
Annals of nuclear medicine.
2011 Jul; 25(6):414-8. doi:
10.1007/s12149-011-0477-z
. [PMID: 21409348] - Timothy R DeGrado, Sandi A Kwee, Marc N Coel, R Edward Coleman. The impact of urinary excretion of (18)F-labeled choline analogs.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2007 Jul; 48(7):1225. doi:
10.2967/jnumed.107.040667
. [PMID: 17607041] - Jonathon A Nye, David M Schuster, Weiping Yu, Vernon M Camp, Mark M Goodman, John R Votaw. Biodistribution and radiation dosimetry of the synthetic nonmetabolized amino acid analogue anti-18F-FACBC in humans.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
2007 Jun; 48(6):1017-20. doi:
10.2967/jnumed.107.040097
. [PMID: 17504867]