2-(Chloromethyl)oxirane; prop-2-en-1-amine (BioDeep_00000837601)
代谢物信息卡片
化学式: C6H12ClNO (149.0607)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C=CCN.C1C(O1)CCl
InChI: 2H,1,3-4H2
描述信息
V - Various > V03 - All other therapeutic products > V03A - All other therapeutic products > V03AE - Drugs for treatment of hyperkalemia and hyperphosphatemia
D064449 - Sequestering Agents > D002614 - Chelating Agents
同义名列表
数据库引用编号
7 个数据库交叉引用编号
- KEGGdrug: D08512
- PubChem: 3085017
- DrugBank: DB00658
- ChEMBL: CHEMBL1201798
- MeSH: Sevelamer
- CAS: 1392212-84-8
- CAS: 52757-95-6
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
亚细胞结构定位 | 关联基因列表 |
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文献列表
- Anja Pfau, Felix Knauf. Authors' Reply: Calcium-Based Phosphate Binders and Plasma Oxalate Concentration in Dialysis Patients.
Journal of the American Society of Nephrology : JASN.
2022 Jul; 33(7):1428. doi:
10.1681/asn.2022030359
. [PMID: 35500939] - Yoshinari Oka, Masashi Miyazaki, Shigeko Takatsu, Hiroaki Matsuda. Calcium-Based Phosphate Binders and Plasma Oxalate Concentration in Dialysis Patients.
Journal of the American Society of Nephrology : JASN.
2022 Jul; 33(7):1427. doi:
10.1681/asn.2022030248
. [PMID: 35500940] - Xiaojun Wang, Yanping Xu, Xiaohong Yu, Asim Dey, Hong Y Zhang, Charity M Zink, Derek Wodka, Gina Porter, William F Matter, Leah Porras, Charles A Reidy, Jeffrey A Peterson, Brian E Mattioni, Joseph V Haas, Mark C Kowala, John R Wetterau. Effects of pharmacological inhibition of the sodium-dependent phosphate cotransporter 2b (NPT2b) on intestinal phosphate absorption in mouse and rat models.
Pharmacology research & perspectives.
2022 04; 10(2):e00938. doi:
10.1002/prp2.938
. [PMID: 35194979] - I R F van Berlo-van de Laar, I Prins-Can, C C M Schuiling-Veninga, K Taxis, F G A Jansman. Exploring co-dispensed drug use in patients on sevelamer or polystyrene sulfonate to identify potential novel binding interactions: a cross sectional in silico study : Potential novel binding interactions with resins.
International journal of clinical pharmacy.
2022 Apr; 44(2):389-398. doi:
10.1007/s11096-021-01355-7
. [PMID: 34850339] - Roopa Satyanarayan Basutkar, Resia Varghese, Nina Kallanthanath Mathew, Prithika Sankar Indira, Balasubramaniam Viswanathan, Ponnusankar Sivasankaran. Systematic review and meta-analysis of potential pleiotropic effects of sevelamer in chronic kidney disease: Beyond phosphate control.
Nephrology (Carlton, Vic.).
2022 Apr; 27(4):337-354. doi:
10.1111/nep.14011
. [PMID: 34882904] - Jeerath Phannajit, Natthaphon Wonghakaeo, Kullaya Takkavatakarn, Thanin Asawavichienjinda, Kearkiat Praditpornsilpa, Somchai Eiam-Ong, Paweena Susantitaphong. The impact of phosphate lowering agents on clinical and laboratory outcomes in chronic kidney disease patients: a systematic review and meta-analysis of randomized controlled trials.
Journal of nephrology.
2022 Mar; 35(2):473-491. doi:
10.1007/s40620-021-01065-3
. [PMID: 34061337] - Darius L Mason, Kavitha Godugu, Daryl Nnani, Shaker A Mousa. Effects of sevelamer carbonate versus calcium acetate on vascular calcification, inflammation, and endothelial dysfunction in chronic kidney disease.
Clinical and translational science.
2022 02; 15(2):353-360. doi:
10.1111/cts.13151
. [PMID: 34599865] - Nicole M Lioufas, Elaine M Pascoe, Carmel M Hawley, Grahame J Elder, Sunil V Badve, Geoffrey A Block, David W Johnson, Nigel D Toussaint. Systematic Review and Meta-Analyses of the Effects of Phosphate-Lowering Agents in Nondialysis CKD.
Journal of the American Society of Nephrology : JASN.
2022 01; 33(1):59-76. doi:
10.1681/asn.2021040554
. [PMID: 34645696] - Lijuan Zhao, An Liu, Guoshuang Xu. Safety and effectiveness of lanthanum carbonate for hyperphosphatemia in chronic kidney disease (CKD) patients: a meta-analysis.
Renal failure.
2021 Dec; 43(1):1378-1393. doi:
10.1080/0886022x.2021.1986068
. [PMID: 34602015] - Kullaya Takkavatakarn, Pongpratch Puapatanakul, Jeerath Phannajit, Warumphon Sukkumme, Pajaree Chariyavilaskul, Patita Sitticharoenchai, Asada Leelahavanichkul, Pisut Katavetin, Kearkiat Praditpornsilpa, Somchai Eiam-Ong, Paweena Susantitaphong. Protein-Bound Uremic Toxins Lowering Effect of Sevelamer in Pre-Dialysis Chronic Kidney Disease Patients with Hyperphosphatemia: A Randomized Controlled Trial.
Toxins.
2021 09; 13(10):. doi:
10.3390/toxins13100688
. [PMID: 34678981] - Jin Hee Lee, Sang Hyoung Park, Jin Ho Shin, Seung-Mo Hong, Jin Hwa Park, Sung Wook Hwang, Dong-Hoon Yang, Jeong-Sik Byeon, Seung-Jae Myung, Byong Duk Ye, Suk-Kyun Yang. [Colonic Mass Secondary to Sevelamer-associated Rectal Ulcer].
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi.
2021 06; 77(6):305-308. doi:
10.4166/kjg.2021.037
. [PMID: 34158451] - Dorien Groenendaal-van de Meent, Virginie Kerbusch, Begona Barroso-Fernandez, Martin den Adel, Jan van Dijk, Georg Golor, Marloes Schaddelee. Effect of the Phosphate Binders Sevelamer Carbonate and Calcium Acetate on the Pharmacokinetics of Roxadustat After Concomitant or Time-separated Administration in Healthy Individuals.
Clinical therapeutics.
2021 06; 43(6):1079-1091. doi:
10.1016/j.clinthera.2021.03.025
. [PMID: 33962762] - Pablo E Pergola, David P Rosenbaum, Yang Yang, Glenn M Chertow. A Randomized Trial of Tenapanor and Phosphate Binders as a Dual-Mechanism Treatment for Hyperphosphatemia in Patients on Maintenance Dialysis (AMPLIFY).
Journal of the American Society of Nephrology : JASN.
2021 06; 32(6):1465-1473. doi:
10.1681/asn.2020101398
. [PMID: 33766811] - Aurelie Lenglet, Mohamad Ali Rahali, François-Ludovic Sauvage, Sophie Liabeuf, Gabriel Choukroun, Marie Essig, Souleiman El Balkhi, Ziad A Massy. Effect of Sevelamer and Nicotinamide on Albumin Carbamylation in Patients with End-Stage Kidney Disease.
Drugs in R&D.
2021 Jun; 21(2):231-238. doi:
10.1007/s40268-021-00350-7
. [PMID: 34101139] - Kathleen M Hill Gallant, Elizabeth R Stremke, Laurie L Trevino, Ranjani N Moorthi, Simit Doshi, Meryl E Wastney, Nozomi Hisada, Jotaro Sato, Yoshitaka Ogita, Naohisa Fujii, Yuya Matsuda, Takei Kake, Sharon M Moe. EOS789, a broad-spectrum inhibitor of phosphate transport, is safe with an indication of efficacy in a phase 1b randomized crossover trial in hemodialysis patients.
Kidney international.
2021 05; 99(5):1225-1233. doi:
10.1016/j.kint.2020.09.035
. [PMID: 33137340] - Maria Spilios, Jerry Altshuler, Sara Radparvar. Safety and feasibility of crushing sevelamer tablets for enteral feeding tube administration.
Journal of clinical pharmacy and therapeutics.
2021 Apr; 46(2):369-372. doi:
10.1111/jcpt.13290
. [PMID: 33037822] - Maria Fusaro, Mario Cozzolino, Mario Plebani, Giorgio Iervasi, Markus Ketteler, Maurizio Gallieni, Andrea Aghi, Francesco Locatelli, John Cunningham, Syazrah Salam, Martina Zaninotto, Maura Ravera, Domenico Russo, Maria Cristina Mereu, Sandro Giannini, Maria Luisa Brandi, Serge Ferrari, Stefania Sella, Colin Gerard Egan, Antonio Bellasi, Luca Di Lullo, Giovanni Tripepi, Thomas Nickolas. Sevelamer Use, Vitamin K Levels, Vascular Calcifications, and Vertebral Fractures in Hemodialysis Patients: Results from the VIKI Study.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
2021 03; 36(3):500-509. doi:
10.1002/jbmr.4214
. [PMID: 33188702] - Nikolina Basic-Jukic, Vesna Furic-Cunko, Ivana Juric, Lea Katalinic. Suicide attempt with sevelamer in a hemodialysis patient.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.
2021 02; 25(1):127-128. doi:
10.1111/1744-9987.13503
. [PMID: 32310338] - Andrew J King, Jill Kohler, Cyra Fung, Zhengfeng Jiang, Allison Quach, Padmapriya Kumaraswamy, Glenn M Chertow, David P Rosenbaum. Combination treatment with tenapanor and sevelamer synergistically reduces urinary phosphorus excretion in rats.
American journal of physiology. Renal physiology.
2021 01; 320(1):F133-F144. doi:
10.1152/ajprenal.00137.2020
. [PMID: 33283643] - Robert Gosik, Krzysztof Danel. The Rising Risk of Chronic Kidney Disease (CKD) and How it is Dealt with: A Review of Current and Potential Phosphate Binders (PB).
Mini reviews in medicinal chemistry.
2021; 21(19):3052-3061. doi:
10.2174/1389557521666210616161728
. [PMID: 34137362] - Peter A McCullough. Phosphate Control: The Next Frontier in Dialysis Cardiovascular Mortality.
Cardiorenal medicine.
2021; 11(3):123-132. doi:
10.1159/000516286
. [PMID: 34120113] - Jürgen Floege. Phosphate binders in chronic kidney disease: an updated narrative review of recent data.
Journal of nephrology.
2020 Jun; 33(3):497-508. doi:
10.1007/s40620-019-00689-w
. [PMID: 31865608] - Lu Dai, Björn K Meijers, Bert Bammens, Henriette de Loor, Leon J Schurgers, Abdul Rashid Qureshi, Peter Stenvinkel, Pieter Evenepoel. Sevelamer Use in End-Stage Kidney Disease (ESKD) Patients Associates with Poor Vitamin K Status and High Levels of Gut-Derived Uremic Toxins: A Drug-Bug Interaction?.
Toxins.
2020 05; 12(6):. doi:
10.3390/toxins12060351
. [PMID: 32471179] - Hui Zheng, Zhinan Liu. Effect of calcitriol combined with sevelamer carbonate on serum parathyroid hormone in patients with chronic renal failure.
Cellular and molecular biology (Noisy-le-Grand, France).
2020 May; 66(2):31-35. doi:
10.14715/cmb/2020.66.2.4
. [PMID: 32415923] - Shogo Takahashi, Yuhuan Luo, Suman Ranjit, Cen Xie, Andrew E Libby, David J Orlicky, Alexander Dvornikov, Xiaoxin X Wang, Komuraiah Myakala, Bryce A Jones, Kanchan Bhasin, Dong Wang, James L McManaman, Kristopher W Krausz, Enrico Gratton, Diana Ir, Charles E Robertson, Daniel N Frank, Frank J Gonzalez, Moshe Levi. Bile acid sequestration reverses liver injury and prevents progression of nonalcoholic steatohepatitis in Western diet-fed mice.
The Journal of biological chemistry.
2020 04; 295(14):4733-4747. doi:
10.1074/jbc.ra119.011913
. [PMID: 32075905] - Charles Ginsberg, Leila R Zelnick, Geoffrey A Block, Glenn M Chertow, Michel Chonchol, Andrew Hoofnagle, Bryan Kestenbaum, Ian H de Boer. Differential effects of phosphate binders on vitamin D metabolism in chronic kidney disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2020 04; 35(4):616-623. doi:
10.1093/ndt/gfaa010
. [PMID: 32160298] - Andreas Brønden, Emil List Larsen, Kristian Karstoft, Trine Henriksen, Tina Vilsbøll, Henrik Enghusen Poulsen, Filip Krag Knop. Changes in oxidative nucleic acid modifications and inflammation following one-week treatment with the bile acid sequestrant sevelamer: Two randomised, placebo-controlled trials.
Journal of diabetes and its complications.
2020 02; 34(2):107446. doi:
10.1016/j.jdiacomp.2019.107446
. [PMID: 31672458] - Annabel Biruete, Kathleen M Hill Gallant, Stephen R Lindemann, Gretchen N Wiese, Neal X Chen, Sharon M Moe. Phosphate Binders and Nonphosphate Effects in the Gastrointestinal Tract.
Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation.
2020 01; 30(1):4-10. doi:
10.1053/j.jrn.2019.01.004
. [PMID: 30846238] - Adrian C Covic, Stuart M Sprague, Anjay Rastogi, Markus Ketteler, Sebastian Walpen, Amandine Perrin, Jürgen Floege. Characteristics of Patients Who Achieve Serum Phosphorus Control on Sucroferric Oxyhydroxide or Sevelamer Carbonate: A post hoc Analysis of a Phase 3 Study.
Nephron.
2020; 144(9):428-439. doi:
10.1159/000507258
. [PMID: 32585670] - Vincent M Brandenburg, Alexander Schuh, Rafael Kramann. Valvular Calcification in Chronic Kidney Disease.
Advances in chronic kidney disease.
2019 11; 26(6):464-471. doi:
10.1053/j.ackd.2019.10.004
. [PMID: 31831124] - David S Wald, John Chambers, Jonathan P Bestwick, Nicholas J Wald. Randomized Crossover Trial of Phosphate-binding Medication on Serum Phosphate Levels in Patients With Aortic Stenosis.
Clinical therapeutics.
2019 10; 41(10):2066-2072.e2. doi:
10.1016/j.clinthera.2019.08.004
. [PMID: 31500854] - Barbara Ruggiero, Matias Trillini, Lida Tartaglione, Silverio Rotondi, Elena Perticucci, Rocco Tripepi, Carolina Aparicio, Veruska Lecchi, Annalisa Perna, Francesco Peraro, Davide Villa, Silvia Ferrari, Antonio Cannata, Sandro Mazzaferro, Francesca Mallamaci, Carmine Zoccali, Antonio Bellasi, Mario Cozzolino, Giuseppe Remuzzi, Piero Ruggenenti, Donald E Kohan. Effects of Sevelamer Carbonate in Patients With CKD and Proteinuria: The ANSWER Randomized Trial.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2019 09; 74(3):338-350. doi:
10.1053/j.ajkd.2019.01.029
. [PMID: 31027883] - Markus Ketteler, Stuart M Sprague, Adrian C Covic, Anjay Rastogi, Bruce Spinowitz, Viatcheslav Rakov, Sebastian Walpen, Jürgen Floege. Effects of sucroferric oxyhydroxide and sevelamer carbonate on chronic kidney disease-mineral bone disorder parameters in dialysis patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2019 07; 34(7):1163-1170. doi:
10.1093/ndt/gfy127
. [PMID: 29846719] - Aurelie Lenglet, Nicolas Fabresse, Méline Taupin, Cathy Gomila, Sophie Liabeuf, Said Kamel, Jean Claude Alvarez, Tilman B Drueke, Ziad A Massy. Does the Administration of Sevelamer or Nicotinamide Modify Uremic Toxins or Endotoxemia in Chronic Hemodialysis Patients?.
Drugs.
2019 Jun; 79(8):855-862. doi:
10.1007/s40265-019-01118-9
. [PMID: 31062264] - Panagiotis Petrou. A systematic review of the economic evaluations of non-calcium-containing phosphate binders, sevelamer and Lanthanum, in end-stage renal disease patients with hyperphosphatemia.
Expert review of pharmacoeconomics & outcomes research.
2019 06; 19(3):287-298. doi:
10.1080/14737167.2019.1567336
. [PMID: 30664365] - Youssef Bennis, Yan Cluet, Dimitri Titeca-Beauport, Najeh El Esper, Pablo Ureña, Sandra Bodeau, Christian Combe, Bertrand Dussol, Denis Fouque, Gabriel Choukroun, Sophie Liabeuf. The Effect of Sevelamer on Serum Levels of Gut-Derived Uremic Toxins: Results from In Vitro Experiments and A Multicenter, Double-Blind, Placebo-Controlled, Randomized Clinical Trial.
Toxins.
2019 05; 11(5):. doi:
10.3390/toxins11050279
. [PMID: 31109001] - Aníbal Ferreira, Bruno Pinto, David Navarro, João Aniceto, Pedro L Neves, Pedro Ponce. Effectiveness of sucroferric oxyhydroxide in patients on on-line hemodiafiltration in real-world clinical practice: A retrospective study.
Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia.
2019 Apr; 41(2):224-230. doi:
10.1590/2175-8239-jbn-2018-0142
. [PMID: 30742699] - Ramya Bhargava, Philip A Kalra, Mark Hann, Paul Brenchley, Helen Hurst, Alastair J Hutchison. A randomized controlled trial of different serum phosphate ranges in subjects on hemodialysis.
BMC nephrology.
2019 02; 20(1):37. doi:
10.1186/s12882-019-1216-2
. [PMID: 30717691] - Akira Maeda, Naoshi Fukushima, Naoshi Horiba, Hiroko Segawa, Ken-Ichi Miyamoto. The Role of Extracellular Phosphate Levels on Kidney Disease Progression in a Podocyte Injury Mouse Model.
Nephron.
2019; 142(2):135-146. doi:
10.1159/000497118
. [PMID: 30731452] - Smiley Annie George, Issam Francis. Pathology of Resin-Induced Gastrointestinal Damage: Report of 15 Cases and Review of Literature.
Turk patoloji dergisi.
2019; 35(3):221-227. doi:
10.5146/tjpath.2018.01458
. [PMID: 31026044] - Xiao Xiao, Yan Liu, Xiaoshi Zhong, Yun Liu, Daoyuan Zhou, Xuan Xiong, Jianmin Ran. Sevelamer hydrochloride suppresses proliferation of parathyroid cells during the early phase of chronic renal failure in rats.
Nephrology (Carlton, Vic.).
2019 Jan; 24(1):127-133. doi:
10.1111/nep.13215
. [PMID: 29278442] - Nobuo Nagano, Ayako Minegishi, Kyoko Ito, Tetsuo Ando, Takaaki Tsutsui, Tetsuya Ogawa. Phosphate Binders Derived from Natural Ores Contain Many Kinds of Metallic Elements Besides Their Active Ingredient Metals.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.
2018 Dec; 22(6):630-634. doi:
10.1111/1744-9987.12704
. [PMID: 29989312] - Allison B Reiss, Nobuyuki Miyawaki, Jane Moon, Lora J Kasselman, Iryna Voloshyna, Robert D'Avino, Joshua De Leon. CKD, arterial calcification, atherosclerosis and bone health: Inter-relationships and controversies.
Atherosclerosis.
2018 11; 278(?):49-59. doi:
10.1016/j.atherosclerosis.2018.08.046
. [PMID: 30253289] - Chinemerem J Okwara, Rishabh Gulati, Tarun Rustagi, Aleksandr Birg, Joshua Hanson, Denis McCarthy. Upper Gastrointestinal Bleeding of Unusual Causation.
Digestive diseases and sciences.
2018 10; 63(10):2541-2546. doi:
10.1007/s10620-018-5260-8
. [PMID: 30178284] - Zahra Golmohamadi, Hassan Argani, Amir Ghorbanihaghjo, Nadereh Rashtchizadeh, Nasrin Bargahi, Mehran Mesgari, Davoud Sanajou. Effect of Sevelamer on Serum Levels of Klotho and Soluble Tumor Necrosis Factor-like Weak Inducer of Apoptosis in Rats With Adenine-induced Chronic Kidney Disease.
Iranian journal of kidney diseases.
2018 Oct; 12(5):281-287. doi:
NULL
. [PMID: 30367019] - Tianbiao Zhou, Hongyan Li, Weiji Xie, Zhijun Lin. A meta-analysis of phosphate binders lanthanum carbonate versus sevelamer hydrochloride in patients with end-stage renal disease undergoing hemodialysis.
African health sciences.
2018 Sep; 18(3):689-696. doi:
10.4314/ahs.v18i3.27
. [PMID: 30603002] - Marinella Ruospo, Suetonia C Palmer, Patrizia Natale, Jonathan C Craig, Mariacristina Vecchio, Grahame J Elder, Giovanni Fm Strippoli. Phosphate binders for preventing and treating chronic kidney disease-mineral and bone disorder (CKD-MBD).
The Cochrane database of systematic reviews.
2018 08; 8(?):CD006023. doi:
10.1002/14651858.cd006023.pub3
. [PMID: 30132304] - Andreas Brønden, Kristian Mikkelsen, David P Sonne, Morten Hansen, Christoffer Våben, Maria N Gabe, Mette Rosenkilde, Valentina Tremaroli, Hao Wu, Fredrik Bäckhed, Jens F Rehfeld, Jens J Holst, Tina Vilsbøll, Filip K Knop. Glucose-lowering effects and mechanisms of the bile acid-sequestering resin sevelamer.
Diabetes, obesity & metabolism.
2018 07; 20(7):1623-1631. doi:
10.1111/dom.13272
. [PMID: 29493868] - Catherine F Roy, Simon F Roy, Lara Richer, Richard Fraser, Sean Gilman. Sevelamer Aspiration.
Journal of bronchology & interventional pulmonology.
2018 07; 25(3):e36-e37. doi:
10.1097/lbr.0000000000000467
. [PMID: 29944594] - Fabio Carfagna, Lucia Del Vecchio, Giuseppe Pontoriero, Francesco Locatelli. Current and potential treatment options for hyperphosphatemia.
Expert opinion on drug safety.
2018 06; 17(6):597-607. doi:
10.1080/14740338.2018.1476487
. [PMID: 29783873] - Eleonora Riccio, Massimo Sabbatini, Dario Bruzzese, Lucia Grumetto, Cristina Marchetiello, Maria Amicone, Michele Andreucci, Bruna Guida, Davide Passaretti, Giacomo Russo, Antonio Pisani. Plasma p-cresol lowering effect of sevelamer in non-dialysis CKD patients: evidence from a randomized controlled trial.
Clinical and experimental nephrology.
2018 Jun; 22(3):529-538. doi:
10.1007/s10157-017-1504-8
. [PMID: 29159529] - Aileen Grace P Arriola, Niels D Martin, Rashmi Tondon. Crystals in Perforated Bowel: Culprits or Innocent Bystanders.
International journal of surgical pathology.
2018 May; 26(3):238-239. doi:
10.1177/1066896917735172
. [PMID: 28982290] - Dengpiao Xie, Naijing Ye, Mingquan Li. A systematic review on the efficacy and safety of PA21 versus sevelamer in dialysis patients.
International urology and nephrology.
2018 May; 50(5):905-909. doi:
10.1007/s11255-017-1774-9
. [PMID: 29294216] - Susana Pastor, Elisabeth Coll, Lara Rodríguez-Ribera, Elitsa Stoyanova, Zuray F Corredor, Ricard Marcos. Influence of Carnicor, Venofer, and Sevelamer on the levels of genotoxic damage in end-stage renal disease patients.
Environmental and molecular mutagenesis.
2018 05; 59(4):302-311. doi:
10.1002/em.22170
. [PMID: 29359355] - Steven Habbous, Sebastian Przech, Janet Martin, Amit X Garg, Sisira Sarma. Cost-Effectiveness of First-Line Sevelamer and Lanthanum versus Calcium-Based Binders for Hyperphosphatemia of Chronic Kidney Disease.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research.
2018 03; 21(3):318-325. doi:
10.1016/j.jval.2017.08.3020
. [PMID: 29566839] - Wendy L St Peter, Lori D Wazny, Eric D Weinhandl. Phosphate-Binder Use in US Dialysis Patients: Prevalence, Costs, Evidence, and Policies.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2018 02; 71(2):246-253. doi:
10.1053/j.ajkd.2017.09.007
. [PMID: 29195858] - Andreas Brønden, Anders Albér, Ulrich Rohde, Laerke S Gasbjerg, Jens F Rehfeld, Jens J Holst, Tina Vilsbøll, Filip K Knop. The bile acid-sequestering resin sevelamer eliminates the acute GLP-1 stimulatory effect of endogenously released bile acids in patients with type 2 diabetes.
Diabetes, obesity & metabolism.
2018 02; 20(2):362-369. doi:
10.1111/dom.13080
. [PMID: 28786523] - Bryan Kestenbaum, Bruce M Psaty. Stuck in a Bind With Phosphate Binders.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2018 02; 71(2):254-256. doi:
10.1053/j.ajkd.2017.08.029
. [PMID: 29224957] - Sahar Fathallah-Shaykh, Dorota Drozdz, Joseph Flynn, Randall Jenkins, Katherine Wesseling-Perry, Sarah J Swartz, Craig Wong, Beverly Accomando, Gerald F Cox, Bradley A Warady. Efficacy and safety of sevelamer carbonate in hyperphosphatemic pediatric patients with chronic kidney disease.
Pediatric nephrology (Berlin, Germany).
2018 02; 33(2):325-333. doi:
10.1007/s00467-017-3787-0
. [PMID: 28900759] - Satoru Mitsuboshi, Hitoshi Yamada, Kazuhiko Nagai, Hideo Okajima. [Low Continuity Rate of Sucroferric Oxyhydroxide among Japanese Hemodialysis Patients with High Phosphate Binder Pill Burden].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
2018; 138(1):135-139. doi:
10.1248/yakushi.17-00180
. [PMID: 29311459] - Thijs T Jansz, Aegida Neradova, Adriana J van Ballegooijen, Marianne C Verhaar, Marc G Vervloet, Leon J Schurgers, Brigit C van Jaarsveld. The role of kidney transplantation and phosphate binder use in vitamin K status.
PloS one.
2018; 13(8):e0203157. doi:
10.1371/journal.pone.0203157
. [PMID: 30161193] - Jang-Hee Cho, Hye Min Jang, Hee-Yeon Jung, Ji-Young Choi, Sun-Hee Park, Chan-Duck Kim, Chul Woo Yang, Dong-Chan Jin, Yong-Lim Kim. A Real-world Cost-effectiveness Analysis of Sevelamer Versus Calcium Acetate in Korean Dialysis Patients.
Clinical therapeutics.
2018 01; 40(1):123-134. doi:
10.1016/j.clinthera.2017.02.005
. [PMID: 28291581] - Sophie Liabeuf, Jean-Philippe Ryckelynck, Najeh El Esper, Pablo Ureña, Christian Combe, Bertrand Dussol, Denis Fouque, Philippe Vanhille, Luc Frimat, Eric Thervet, Romuald Mentaverri, Dominique Prié, Gabriel Choukroun. Randomized Clinical Trial of Sevelamer Carbonate on Serum Klotho and Fibroblast Growth Factor 23 in CKD.
Clinical journal of the American Society of Nephrology : CJASN.
2017 Dec; 12(12):1930-1940. doi:
10.2215/cjn.03030317
. [PMID: 29074818] - Hirotaka Komaba, Mia Wang, Masatomo Taniguchi, Suguru Yamamoto, Takanobu Nomura, Douglas E Schaubel, Abigail R Smith, Jarcy Zee, Angelo Karaboyas, Brian Bieber, Masafumi Fukagawa, Francesca Tentori. Initiation of Sevelamer and Mortality among Hemodialysis Patients Treated with Calcium-Based Phosphate Binders.
Clinical journal of the American Society of Nephrology : CJASN.
2017 Sep; 12(9):1489-1497. doi:
10.2215/cjn.13091216
. [PMID: 28724618] - Susanne Johansson, Maria Leonsson-Zachrisson, Mikael Knutsson, Andrew G Spencer, Eric D Labonté, Desiree Deshpande, Jill Kohler, Kenji Kozuka, Dominique Charmot, David P Rosenbaum. Preclinical and Healthy Volunteer Studies of Potential Drug-Drug Interactions Between Tenapanor and Phosphate Binders.
Clinical pharmacology in drug development.
2017 Sep; 6(5):448-456. doi:
10.1002/cpdd.307
. [PMID: 27654985] - Wendy L St. Peter, Lori D Wazny, Eric Weinhandl, Katie E Cardone, Joanna Q Hudson. A Review of Phosphate Binders in Chronic Kidney Disease: Incremental Progress or Just Higher Costs?.
Drugs.
2017 07; 77(11):1155-1186. doi:
10.1007/s40265-017-0758-5
. [PMID: 28584909] - Gonzalo A Bravo-Soto, Trinidad Madrid. Sevelamer versus calcium-based phosphate binders for chronic kidney disease.
Medwave.
2017 May; 17(Suppl2):e6942. doi:
10.5867/medwave.2017.6942
. [PMID: 28525528] - Aurélie Lenglet, Sophie Liabeuf, Najeh El Esper, Sandrine Brisset, Janette Mansour, Anne-Sophie Lemaire-Hurtel, Aurelien Mary, Michel Brazier, Said Kamel, Romuald Mentaverri, Gabriel Choukroun, Albert Fournier, Ziad A Massy. Efficacy and safety of nicotinamide in haemodialysis patients: the NICOREN study.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2017 May; 32(5):870-879. doi:
10.1093/ndt/gfw042
. [PMID: 27190329] - Pablo Antonio Ureña Torres. [Strategies aiming to control hyperphosphatemia in chronic kidney disease].
Nephrologie & therapeutique.
2017 Apr; 13 Suppl 1(?):S95-S101. doi:
10.1016/j.nephro.2017.01.002
. [PMID: 28577750] - Pierre Bataille, Vincent Delattre, Maité Daroux. [Sucroferric oxyhydroxide, a novel iron-based phosphate binder. Which current use in dialysis patients?].
Nephrologie & therapeutique.
2017 Apr; 13 Suppl 1(?):S103-S108. doi:
10.1016/j.nephro.2017.01.004
. [PMID: 28577730] - Fumihiko Koiwa, Keitaro Yokoyama, Masafumi Fukagawa, Akira Terao, Tadao Akizawa. Efficacy and safety of sucroferric oxyhydroxide compared with sevelamer hydrochloride in Japanese haemodialysis patients with hyperphosphataemia: A randomized, open-label, multicentre, 12-week phase III study.
Nephrology (Carlton, Vic.).
2017 Apr; 22(4):293-300. doi:
10.1111/nep.12891
. [PMID: 27496336] - Indranil Dasgupta, Rukshana Shroff. Phosphate Binders and Mortality: There Is a Need for More Evidence.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2017 03; 69(3):481. doi:
10.1053/j.ajkd.2016.10.038
. [PMID: 28236882] - Maurizio Gallieni, Piergiorgio Messa. A Survival Benefit With Phosphate-Binder Treatment in CKD Patients Cannot Be Excluded.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2017 03; 69(3):481-482. doi:
10.1053/j.ajkd.2016.10.041
. [PMID: 28236881] - Rohan M Modi, Benjamin Swanson, Vijay Duggirala. Long-Standing Diarrhea Associated With Sevelamer Crystalopathy in Colonic Mucosa.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
2017 02; 15(2):A26-A27. doi:
10.1016/j.cgh.2016.10.025
. [PMID: 27989850] - Atsushi Yaguchi, Satoshi Tatemichi, Hiroo Takeda, Mamoru Kobayashi. PA21, a novel phosphate binder, improves renal osteodystrophy in rats with chronic renal failure.
PloS one.
2017; 12(7):e0180430. doi:
10.1371/journal.pone.0180430
. [PMID: 28704404] - Joanna Matuszkiewicz-Rowińska, Małgorzata Kościelska. [Current approaches in the treatment of hyperphosphatemia in chronic kidney disease].
Wiadomosci lekarskie (Warsaw, Poland : 1960).
2017 ; 70(6 pt 2):1161-1165. doi:
NULL
. [PMID: 29533905] - Steven Habbous, Sebastian Przech, Rey Acedillo, Sisira Sarma, Amit X Garg, Janet Martin. The efficacy and safety of sevelamer and lanthanum versus calcium-containing and iron-based binders in treating hyperphosphatemia in patients with chronic kidney disease: a systematic review and meta-analysis.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2017 01; 32(1):111-125. doi:
10.1093/ndt/gfw312
. [PMID: 27651467] - Ellen Neven, Britt Opdebeeck, Annelies De Maré, Rida Bashir-Dar, Geert Dams, Rita Marynissen, Geert J Behets, Anja Verhulst, Bruce L Riser, Patrick C D'Haese. Can Intestinal Phosphate Binding or Inhibition of Hydroxyapatite Growth in the Vascular Wall Halt the Progression of Established Aortic Calcification in Chronic Kidney Disease?.
Calcified tissue international.
2016 11; 99(5):525-534. doi:
10.1007/s00223-016-0178-7
. [PMID: 27461215] - Li Yang, Seng Chuen Tan, Can Chen, Xingzhi Wang, Xinya Li, Xiaoyan Yang. Economic Evaluation of Sevelamer versus Calcium-based Binders in Treating Hyperphosphatemia among Patients with End-stage Renal Disease in China.
Clinical therapeutics.
2016 Nov; 38(11):2459-2467.e1. doi:
10.1016/j.clinthera.2016.09.012
. [PMID: 27751671] - Michael Copland, Paul Komenda, Eric D Weinhandl, Peter A McCullough, Jose A Morfin. Intensive Hemodialysis, Mineral and Bone Disorder, and Phosphate Binder Use.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2016 Nov; 68(5S1):S24-S32. doi:
10.1053/j.ajkd.2016.05.024
. [PMID: 27772640] - Suetonia C Palmer, Sharon Gardner, Marcello Tonelli, Dimitris Mavridis, David W Johnson, Jonathan C Craig, Richard French, Marinella Ruospo, Giovanni F M Strippoli. Phosphate-Binding Agents in Adults With CKD: A Network Meta-analysis of Randomized Trials.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2016 Nov; 68(5):691-702. doi:
10.1053/j.ajkd.2016.05.015
. [PMID: 27461851] - Medha Airy, Wolfgang C Winkelmayer, Sankar D Navaneethan. Phosphate Binders: The Evidence Gap Persists.
American journal of kidney diseases : the official journal of the National Kidney Foundation.
2016 11; 68(5):667-670. doi:
10.1053/j.ajkd.2016.08.008
. [PMID: 27772629] - Sung Min Ko, Chao Zhang, Zhengjia Chen, Luis D'Marco, Antonio Bellasi, Arthur E Stillman, Geoffrey Block, Paolo Raggi. Epicardial adipose tissue volume increase in hemodialysis patients treated with sevelamer or calcium-based phosphate binders: a substudy of the Renagel in new dialysis trial.
Journal of nephrology.
2016 Oct; 29(5):683-90. doi:
10.1007/s40620-016-0310-9
. [PMID: 27102490] - Antonio Bellasi, Mario Cozzolino, Domenico Russo, Donald Molony, Biagio Di Iorio. Cinacalcet but not vitamin D use modulates the survival benefit associated with sevelamer in the INDEPENDENT study.
Clinical nephrology.
2016 Sep; 86(9):113-24. doi:
10.5414/cn108827
. [PMID: 27443567] - Timothy Nguyen, Trung Pham, Tommy Huynh. Phosphate binder choices used in ESRD patients.
Nephrology news & issues.
2016 Aug; 30(8):37-38. doi:
NULL
. [PMID: 30513170] - Rana Rizk. Cost-effectiveness of phosphate binders among patients with chronic kidney disease not yet on dialysis: a long way to go.
BMC nephrology.
2016 07; 17(1):75. doi:
10.1186/s12882-016-0286-7
. [PMID: 27393192] - Pilar Monge Rafael, Manuel Arias, Gema Fernández-Fresnedo. Severe hypocalcemia following denosumab injection in patient with chronic kidney disease.
Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia.
2016 Jul; 36(4):446-8. doi:
10.1016/j.nefro.2016.02.007
. [PMID: 27012438] - Jürgen Floege. Phosphate binders in chronic kidney disease: a systematic review of recent data.
Journal of nephrology.
2016 Jun; 29(3):329-340. doi:
10.1007/s40620-016-0266-9
. [PMID: 26800972] - A Yaguchi, S Yonekubo, I Maruyama, S Tatemichi, K Maruyama, M Kobayashi. Comparison of Phosphate Binding Capacities of PA21, A Novel Phosphate Binder, with those of other Phosphate Binders in vitro and in vivo.
Drug research.
2016 May; 66(5):262-9. doi:
10.1055/s-0035-1569328
. [PMID: 26761712] - Benjamin Seront, Liliane Marot, Nathalie Demoulin, Michel Jadoul, Johann Morelle. The Case Subcutaneous abdominal calcified nodules and severe hyperphosphatemia.
Kidney international.
2016 May; 89(5):1171-1172. doi:
10.1016/j.kint.2015.10.017
. [PMID: 27083299] - Hai V Nguyen, Saideep Bose, Eric Finkelstein. Incremental cost-utility of sevelamer relative to calcium carbonate for treatment of hyperphosphatemia among pre-dialysis chronic kidney disease patients.
BMC nephrology.
2016 04; 17(1):45. doi:
10.1186/s12882-016-0256-0
. [PMID: 27121505] - Ryota Ikee, Takayuki Toyoyama, Toko Endo, Masataka Tsunoda, Nobuo Hashimoto. Impact of sevelamer hydrochloride on serum magnesium concentrations in hemodialysis patients.
Magnesium research.
2016 Apr; 29(4):184-190. doi:
10.1684/mrh.2016.0410
. [PMID: 27965186] - Hsin-Hung Lin, Hung-Hsiang Liou, Ming-Shiou Wu, Chiu-Ching Huang. Factors associated with serum fetuin-A concentrations after long-term use of different phosphate binders in hemodialysis patients.
BMC nephrology.
2016 Mar; 17(?):33. doi:
10.1186/s12882-016-0245-3
. [PMID: 27007989] - Christina Tieu, Roger K Moreira, Louis M Wong Kee Song, Shounak Majumder, Konstantinos A Papadakis, Marie C Hogan. A case report of sevelamer-associated recto-sigmoid ulcers.
BMC gastroenterology.
2016 Feb; 16(?):20. doi:
10.1186/s12876-016-0441-4
. [PMID: 26911806] - Leena Patel, Lisa M Bernard, Grahame J Elder. Sevelamer Versus Calcium-Based Binders for Treatment of Hyperphosphatemia in CKD: A Meta-Analysis of Randomized Controlled Trials.
Clinical journal of the American Society of Nephrology : CJASN.
2016 Feb; 11(2):232-44. doi:
10.2215/cjn.06800615
. [PMID: 26668024] - Joseph Kim, Kristin Olson, Lavjay Butani. Sevelamer crystals in the mucosa of the gastrointestinal tract in a teenager with end-stage renal disease.
Pediatric nephrology (Berlin, Germany).
2016 Feb; 31(2):339-41. doi:
10.1007/s00467-015-3269-1
. [PMID: 26563116] - Yuko Iwashita, Yu Iwashita, Takafumi Ito, Takashi Shigematsu. [Treatment for CKD-MBD(Chronic Kidney Disease-Mineral and Bone Disorder)].
Clinical calcium.
2016 Feb; 26(2):259-67. doi:
clica1602259267
. [PMID: 26813506] - Yongsheng Yang, Adil Mohammad, Robert T Berendt, Alan Carlin, Mansoor A Khan, Patrick J Faustino. Evaluation of the In Vitro Efficacy of Sevelamer Hydrochloride and Sevelamer Carbonate.
Journal of pharmaceutical sciences.
2016 Feb; 105(2):864-875. doi:
10.1002/jps.24572
. [PMID: 26219932] - Carmine Zoccali, Francesca Mallamaci. Moderator's view: Phosphate binders in chronic kidney disease patients: a clear 'No' at the moment, but stay tuned.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
2016 Feb; 31(2):196-9. doi:
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