Omidenepag Isopropyl (BioDeep_00000837593)
代谢物信息卡片
化学式: C26H28N6O4S (520.1892648)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)OC(=O)CNC1=CC=CC(=N1)CN(CC2=CC=C(C=C2)N3C=CC=N3)S(=O)(=O)C4=CN=CC=C4
InChI: InChI=1S/C26H28N6O4S/c1-20(2)36-26(33)17-28-25-8-3-6-22(30-25)19-31(37(34,35)24-7-4-13-27-16-24)18-21-9-11-23(12-10-21)32-15-5-14-29-32/h3-16,20H,17-19H2,1-2H3,(H,28,30)
描述信息
C78283 - Agent Affecting Organs of Special Senses > C29705 - Anti-glaucoma Agent
同义名列表
1 个代谢物同义名
数据库引用编号
5 个数据库交叉引用编号
- KEGGdrug: D10966
- PubChem: 44230999
- DrugBank: DB15071
- ChEMBL: CHEMBL4297666
- CAS: 1187451-19-9
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yosuke Ida, Megumi Watanabe, Araya Umetsu, Hiroshi Ohguro, Fumihito Hikage. Addition of EP2 agonists to an FP agonist additively and synergistically modulates adipogenesis and the physical properties of 3D 3T3-L1 sphenoids.
Prostaglandins, leukotrienes, and essential fatty acids.
2021 08; 171(?):102315. doi:
10.1016/j.plefa.2021.102315. [PMID: 34246925] - Yosuke Ida, Megumi Watanabe, Hiroshi Ohguro, Fumihito Hikage. Simultaneous Use of ROCK Inhibitors and EP2 Agonists Induces Unexpected Effects on Adipogenesis and the Physical Properties of 3T3-L1 Preadipocytes.
International journal of molecular sciences.
2021 Apr; 22(9):. doi:
10.3390/ijms22094648. [PMID: 33925005] - Yosuke Ida, Fumihito Hikage, Araya Umetsu, Haruka Ida, Hiroshi Ohguro. Omidenepag, a non-prostanoid EP2 receptor agonist, induces enlargement of the 3D organoid of 3T3-L1 cells.
Scientific reports.
2020 09; 10(1):16018. doi:
10.1038/s41598-020-72538-x. [PMID: 32994409] - Yasuko Yamamoto, Takazumi Taniguchi, Tomoaki Inazumi, Ryo Iwamura, Kenji Yoneda, Noriko Odani-Kawabata, Takeshi Matsugi, Yukihiko Sugimoto, Naveed K Shams. Effects of the Selective EP2 Receptor Agonist Omidenepag on Adipocyte Differentiation in 3T3-L1 Cells.
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.
2020 04; 36(3):162-169. doi:
10.1089/jop.2019.0079. [PMID: 31934812] - Makoto Aihara, Fenghe Lu, Hisashi Kawata, Yuki Tanaka, Kenzo Yamamura, Noriko Odani-Kawabata, Naveed K Shams. Pharmacokinetics, Safety, and Intraocular Pressure-Lowering Profile of Omidenepag Isopropyl, a Selective, Nonprostaglandin, Prostanoid EP2 Receptor Agonist, in Healthy Japanese and Caucasian Volunteers (Phase I Study).
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.
2019 12; 35(10):542-550. doi:
10.1089/jop.2019.0044. [PMID: 31674861]