Prasterone acetate (BioDeep_00000832322)
代谢物信息卡片
化学式: C21H30O3 (330.2195)
中文名称: 醋酸去氢表雄酮
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)OC1CCC2(C3CCC4(C(C3CC=C2C1)CCC4=O)C)C
InChI: InChI=1S/C21H30O3/c1-13(22)24-15-8-10-20(2)14(12-15)4-5-16-17-6-7-19(23)21(17,3)11-9-18(16)20/h4,15-18H,5-12H2,1-3H3/t15-,16-,17-,18-,20-,21-/m0/s1
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
同义名列表
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Saurabh Aggarwal, Suresh Thareja, T R Bhardwaj, Jörg Haupenthal, R W Hartmann, Manoj Kumar. Synthesis and biological evaluation of novel unsaturated carboxysteroids as human 5α-reductase inhibitors: a legitimate approach.
European journal of medicinal chemistry.
2012 Aug; 54(?):728-39. doi:
10.1016/j.ejmech.2012.06.026. [PMID: 22776417] - A Takeuchi, S Masuda, H Saito, T Abe, K Inui. Multispecific substrate recognition of kidney-specific organic anion transporters OAT-K1 and OAT-K2.
The Journal of pharmacology and experimental therapeutics.
2001 Oct; 299(1):261-7. doi:
NULL. [PMID: 11561088] - H Goto, S Yamashita, T Makita. Preventive effects of dehydroepiandrosterone acetate on the fatty liver induced by orotic acid in male rats.
Experimental animals.
1998 Oct; 47(4):257-60. doi:
10.1538/expanim.47.257. [PMID: 10067169] - M A Graf, P Bielfeld, W Distler, C Weiers, W N Kühn-Velten. Pulsatile luteinizing hormone secretion pattern in hyperandrogenemic women.
Fertility and sterility.
1993 Apr; 59(4):761-7. doi:
10.1016/s0015-0282(16)55856-7. [PMID: 8458493] - D C Cumming. Androgenesis and androdynamics in normal women.
Cleveland Clinic journal of medicine.
1990 Mar; 57(2):161-6. doi:
10.3949/ccjm.57.2.161. [PMID: 2157560] - M K McIntosh, C D Berdanier. Differential effects of adrenalectomy and starvation-refeeding on hepatic lipogenic responses to dehydroepiandrosterone and glucocorticoid in BHE and Sprague-Dawley rats.
The Journal of nutrition.
1988 Aug; 118(8):1011-7. doi:
10.1093/jn/118.8.1011. [PMID: 2969962] - L Markiewicz, E Gurpide. C19 adrenal steroids enhance prostaglandin F2 alpha output by human endometrium in vitro.
American journal of obstetrics and gynecology.
1988 Aug; 159(2):500-4. doi:
10.1016/s0002-9378(88)80117-0. [PMID: 2970223] - B Leighton, A R Tagliaferro, E A Newsholme. The effect of dehydroepiandrosterone acetate on liver peroxisomal enzyme activities of male and female rats.
The Journal of nutrition.
1987 Jul; 117(7):1287-90. doi:
10.1093/jn/117.7.1287. [PMID: 2956380] - A R Tagliaferro, J R Davis, S Truchon, N Van Hamont. Effects of dehydroepiandrosterone acetate on metabolism, body weight and composition of male and female rats.
The Journal of nutrition.
1986 Oct; 116(10):1977-83. doi:
10.1093/jn/116.10.1977. [PMID: 2945908] - L JACOBSSON. Hamburger's 'micro' method for neutral 17-ketosteroids. The recovery of dehydroisoandrosterone acetate added to water and urine.
Scandinavian journal of clinical and laboratory investigation.
1951; 3(3):250-1. doi:
10.3109/00365515109060610. [PMID: 14900977]
