EMIGLITATE (BioDeep_00000831222)
代谢物信息卡片
化学式: C17H25NO7 (355.1631)
中文名称: 乙格列酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCOC(=O)C1=CC=C(C=C1)OCCN2CC(C(C(C2CO)O)O)O
InChI: InChI=1S/C17H25NO7/c1-2-24-17(23)11-3-5-12(6-4-11)25-8-7-18-9-14(20)16(22)15(21)13(18)10-19/h3-6,13-16,19-22H,2,7-10H2,1H3/t13-,14+,15-,16-/m1/s1
描述信息
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
C471 - Enzyme Inhibitor
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- B Lembcke, U R Fölsch, W Gatzemeier, B Lücke, R Ebert, E Siegel, W Creutzfeldt. Inhibition of sucrose- and starch-induced glycaemic and hormonal responses by the alpha-glucosidase inhibitor emiglitate (BAY o 1248) in healthy volunteers.
European journal of clinical pharmacology.
1991; 41(6):561-7. doi:
10.1007/bf00314985. [PMID: 1815967] - M Serrano-Rios, J Sabán, I Navascués, J F Cañizo, I Hillebrand. Effect of two new alpha-glucosidase inhibitors in insulin-dependent diabetic patients.
Diabetes research and clinical practice.
1988 Jan; 4(2):111-6. doi:
10.1016/s0168-8227(88)80005-6. [PMID: 3277827] - J Gerard, I Hillebrand, P J Lefèbvre. Assessment of the clinical efficacy and tolerance of two new alpha-glucosidase inhibitors in insulin-treated diabetics.
International journal of clinical pharmacology, therapy, and toxicology.
1987 Sep; 25(9):483-8. doi:
. [PMID: 3316059] - F P Kennedy, J M Miles, V Heiling, J E Gerich. The effect of two new alpha-glucosidase inhibitors on metabolic responses to a mixed meal in normal volunteers.
Clinical and experimental pharmacology & physiology.
1987 Aug; 14(8):633-40. doi:
10.1111/j.1440-1681.1987.tb01884.x. [PMID: 3326689] - K F Federlin, L Mehlburger, I Hillebrand, H Laube. The effect of two new glucosidase inhibitors on blood glucose in healthy volunteers and in type II diabetics.
Acta diabetologica latina.
1987 Jul; 24(3):213-21. doi:
10.1007/bf02732040. [PMID: 3687313] - S M Lee, S Bustamante, C Flores, J Bezerra, T Goda, O Koldovský. Chronic effects of an alpha-glucosidase inhibitor (Bay o 1248) on intestinal disaccharidase activity in normal and diabetic mice.
The Journal of pharmacology and experimental therapeutics.
1987 Jan; 240(1):132-7. doi:
NULL. [PMID: 3100764] - B Göke, H C Fehmann, E G Siegel, U R Fölsch, W Creutzfeldt. Influence of an absorbable alpha-glucosidase inhibitor (Bay o 1248) on the endocrine and exocrine pancreas of the rat.
Zeitschrift fur Gastroenterologie.
1986 Dec; 24(12):758-66. doi:
NULL. [PMID: 2435069] - Z Madar, J Olefsky. Effect of the alpha-glucosidase inhibitor Bay-O-1248 on the metabolic response of nondiabetic and diabetic rats to a high-carbohydrate diet.
The American journal of clinical nutrition.
1986 Aug; 44(2):206-11. doi:
10.1093/ajcn/44.2.206. [PMID: 3728357] - M Cauderay, L Tappy, E Temler, E Jéquier, I Hillebrand, J P Felber. Effect of alpha-glycohydrolase inhibitors (Bay m1099 and Bay o1248) on sucrose metabolism in normal men.
Metabolism: clinical and experimental.
1986 May; 35(5):472-7. doi:
10.1016/0026-0495(86)90140-x. [PMID: 3517560] - I Hillebrand, K Boehme, K H Graefe, K Wehling. The effect of new alpha-glucosidase inhibitors (BAY m 1099 and BAY o 1248) on meal-stimulated increases in glucose and insulin levels in man.
Klinische Wochenschrift.
1986 Apr; 64(8):393-6. doi:
10.1007/bf01728191. [PMID: 3517475]
