choline magnesium trisalicylate (BioDeep_00000831203)
代谢物信息卡片
化学式: C26H29MgNO10 (539.1641874000001)
中文名称: 三水杨酸胆碱镁
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C[N+](C)(C)CCO.C1=CC=C(C(=C1)C(=O)O)[O-].C1=CC=C(C(=C1)C(=O)O)[O-].C1=CC=C(C(=C1)C(=O)O)[O-].[Mg+2]
InChI: +1
描述信息
D000893 - Anti-Inflammatory Agents > D000894 - Anti-Inflammatory Agents, Non-Steroidal > D012459 - Salicylates
C78272 - Agent Affecting Nervous System > C241 - Analgesic Agent > C2198 - Nonnarcotic Analgesic
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
D018501 - Antirheumatic Agents
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- T S Tracy, K Krohn, D R Jones, J D Bradley, S D Hall, D C Brater. The effects of a salicylate, ibuprofen, and naproxen on the disposition of methotrexate in patients with rheumatoid arthritis.
European journal of clinical pharmacology.
1992; 42(2):121-5. doi:
10.1007/bf00278469. [PMID: 1618240] - E Nizankowska, R Dworski, J Soja, A Szczeklik. Salicylate pre-treatment attenuates intensity of bronchial and nasal symptoms precipitated by aspirin in aspirin-intolerant patients.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.
1990 Nov; 20(6):647-52. doi:
10.1111/j.1365-2222.1990.tb02703.x. [PMID: 2083404] - A Szczeklik, E Nizankowska, R Dworski. Choline magnesium trisalicylate in patients with aspirin-induced asthma.
The European respiratory journal.
1990 May; 3(5):535-9. doi:
NULL. [PMID: 2198165] - B J Danesh, M McLaren, R I Russell, G D Lowe, C D Forbes. Comparison of the effect of aspirin and choline magnesium trisalicylate on thromboxane biosynthesis in human platelets: role of the acetyl moiety.
Haemostasis.
1989; 19(3):169-73. doi:
10.1159/000215911. [PMID: 2744633] - B J Danesh, M McLaren, R I Russell, G D Lowe, C D Forbes. Does non-acetylated salicylate inhibit thromboxane biosynthesis in human platelets?.
Scottish medical journal.
1988 Aug; 33(4):315-6. doi:
10.1177/003693308803300416. [PMID: 3187504] - D E Furst, E Sarkissian, K Blocka, S Cassell, S Dromgoole, E R Harris, J M Hirschberg, N Josephson, H E Paulus. Serum concentrations of salicylate and naproxen during concurrent therapy in patients with rheumatoid arthritis.
Arthritis and rheumatism.
1987 Oct; 30(10):1157-61. doi:
10.1002/art.1780301011. [PMID: 3675660] - R J Cersosimo, S J Matthews. Hepatotoxicity associated with choline magnesium trisalicylate: case report and review of salicylate-induced hepatotoxicity.
Drug intelligence & clinical pharmacy.
1987 Jul; 21(7-8):621-5. doi:
10.1177/1060028087021007-810. [PMID: 3301251] - D E Furst, K Blocka, S Cassell, E R Harris, J M Hirschberg, N Josephson, P A Lachenbruch, R B Trimble, H E Paulus. A controlled study of concurrent therapy with a nonacetylated salicylate and naproxen in rheumatoid arthritis.
Arthritis and rheumatism.
1987 Feb; 30(2):146-54. doi:
10.1002/art.1780300204. [PMID: 3548732] - B J Danesh, L M Nelson, R I Russell, C Docherty. Replacing the acetyl linkage in aspirin with choline and magnesium moieties reduces the occurrence of gastric mucosal injury.
Alimentary pharmacology & therapeutics.
1987 Feb; 1(1):51-6. doi:
10.1111/j.1365-2036.1987.tb00606.x. [PMID: 2979212] - M Helliwell, T Gibson, D Berry, G Volans. A pharmacokinetic comparison of choline magnesium trisalicylate and soluble aspirin.
British journal of rheumatology.
1984 Nov; 23(4):288-91. doi:
10.1093/rheumatology/23.4.288. [PMID: 6487934] - M J Levitt, J Kann. Choline magnesium trisalicylate: comparative pharmacokinetic study of once-daily and twice-daily dosages.
Journal of pharmaceutical sciences.
1984 Jul; 73(7):977-9. doi:
10.1002/jps.2600730729. [PMID: 6470965] - K G Mitchell, J Hearns, G P Crean. The effect of the non-steroidal anti-inflammatory drug choline magnesium trisalicylate on gastric mucosal cell exfoliation.
British journal of clinical pharmacology.
1984 Jan; 17(1):27-30. doi:
10.1111/j.1365-2125.1984.tb04994.x. [PMID: 6691886] - A Kilander, G Dotevall. Endoscopic evaluation of the comparative effects of acetylsalicylic acid and choline magnesium trisalicylate on human gastric and duodenal mucosa.
British journal of rheumatology.
1983 Feb; 22(1):36-40. doi:
10.1093/rheumatology/22.1.36. [PMID: 6337663] - M H Binus, J A Lyon, J L Nicholas. Comparable serum salicylate concentrations from choline magnesium trisalicylate, aspirin, and buffered aspirin in rheumatoid arthritis.
Arthritis and rheumatism.
1982 Apr; 25(4):464-6. doi:
10.1002/art.1780250418. [PMID: 7073776] - W D Mason. Comparative plasma salicylate and urine salicylurate levels following administration of aspirin, magnesium salicylate, and choline magnesium trisalicylate.
Journal of pharmaceutical sciences.
1980 Nov; 69(11):1355-6. doi:
10.1002/jps.2600691133. [PMID: 7452472]